Syllabus for Molecular Cell Biology

Molekylär cellbiologi

A revised version of the syllabus is available.

Syllabus

  • 15 credits
  • Course code: 1BG320
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Biology A1N

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle
    G1N: has only upper-secondary level entry requirements
    G1F: has less than 60 credits in first-cycle course/s as entry requirements
    G1E: contains specially designed degree project for Higher Education Diploma
    G2F: has at least 60 credits in first-cycle course/s as entry requirements
    G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    GXX: in-depth level of the course cannot be classified.

    Second cycle
    A1N: has only first-cycle course/s as entry requirements
    A1F: has second-cycle course/s as entry requirements
    A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    AXX: in-depth level of the course cannot be classified.

  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2007-03-15
  • Established by: The Faculty Board of Science and Technology
  • Revised: 2010-04-15
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 31, 2010
  • Entry requirements:
  • Responsible department: Biology Education Centre

Content

In the course, the following part is included

Signal transduction: The principles for chemical communication between cells; signal molecules and receptors, components in intracellular signal paths and their function

The cytoskeleton: The architecture and the dynamics at the three cytoskeleton systems and their motor proteins

Adhesion: Proteins in the extracellular matrix and the cellular adhesions proteins and their interactions; various types of adhesions complexes; the nerve synapse as examples of a specialised cell contact

The cell cycle: Regulation and mechanisms for cell replication in prokaryotes and eukaryotes; the importance of molecular mechanisms for origin of cancer growth

Transcription: The roles of general and specific transcription factors for the initiation of the transcription, protein-DNA interaction, the mRNA processing

Translation and protein targeting: Mechanisms for regulation of initiation of the translation, mechanisms for the peptide synthesis and the control of the precision in the synthesis, the protein processing and quality control in endoplasmic reticulum, the vesicle carried protein transport

Computer exercises: The mechanistic details of different processes are studied in a number of computer exercises, where the detailed macro molecules and their interactions are analysed

Laboratory work: Cultivation of mammal cells, fluorescence microscopy, immunoprecipitering of protein, gels of the SDS-PAGE and silver staining.

Project: The students work in groups with a chosen current research field within the subject. The results are presented as a posts and a short oral presentation.

Reading list

Reading list

Applies from: week 32, 2010

  • Lodish, Harvey F. Molecular cell biology

    6. ed.: New York: W.H. Freeman, cop. 2008

    Find in the library

  • Lodish, Harvey F. Molecular cell biology

    5. ed.: New York: W. H. Freeman and Co., 2003

    Find in the library