Entry requirements

The overview course Chemical Principles I, 10 credits or equivalent.

Learning outcomes

After a pass mark on course, the student should be able to:

• name organic compounds from the major classes, use stereochemical terminology to describe the three-dimensional structure of organic compounds and correlate chemical and physical properties or organic compounds to their structure
• account for basic organic reactions such as proton transfer, addition, substitution, elimination, oxidation and reduction in organic chemistry
• explain and account for technical production and industrial use of some important organic compounds and carry out basic economical and environmental assessments in connection thereby
• describe the structure of commonly occurring biomolecules and synthetic macromolecules and be familiar with spectroscopic methods routinely used by organic chemists
• plan and carry out laboratory work in a correct and safe manner, carry out simple risk and security assessments, document laboratory work in a lab log and account for the results of the laboratory session orally and in writing

Content

Chemical bonds, Lewis structures, formal charge, functional groups. Conformations of molecules. Physical properties (melting, boiling, solubility) in relation to structure. Stereochemistry, stereochemical concepts. Acids and bases, pKa, the relation between structure and acid/base strength. Alkenes, alkynes conjugated systems, arenas, aromaticity, absorption of light. Electrophiles, nucleophiles. Addition, substitution and elimination reactions. Reactions classifications (SN1, SN2, E1, E2). Reactions of alcohols, amines, ethers, epoxides. Carboxylic acids and derivatives (esters, amides) and their reactions. Reactions of aldehydes and ketones. Radicals and reactions involving radicals. Reactions of arenes. Carbohydrates, amino acids, peptides, proteins, lipids. Bulk polymers, addition polymers, condensation polymers. Laboratory work: Organic syntheses that illustrate both theory and different laboratory technologies that are used for preparation, workup and characterisation of organic compounds.

Instruction

The teaching is given as lectures, lessons and laboratory sessions. Laboratory sessions and connected overviews and presentations are compulsory. Communication training and profile according to chosen specialisation integrated with other course parts.

Assessment

Written examination at the end of the course corresponds to 5 credits. Passed laboratory work equivalent to 4 credits is required passed chemistry profile/assignment, 1 credit, to pass the course. The final grade of the course is based on both the written examination and the laboratory assignments.