Moritz Senger
Researcher at Department of Chemistry - BMC; Biochemistry; Senger Group
- E-mail:
- moritz.senger@kemi.uu.se
- Visiting address:
- Husargatan 3
752 37 Uppsala - Postal address:
- Box 576
75123 Uppsala
Visiting researcher at Department of Chemistry - Ångström Laboratory; Molecular Biomimetics; Biophysical and Bioinorganic Chemistry
- E-mail:
- moritz.senger@kemi.uu.se
- Visiting address:
- Ångströmlaboratoriet, Lägerhyddsvägen 1
75120 Uppsala - Postal address:
- Box 523
75120 Uppsala
- CV:
- Download CV
- ORCID:
- 0000-0001-9225-4910
Short presentation
Enzymatic catalysis investigated by time-resolved spectroscopy and crystallography for sustainable energy solutions
Google Scholar: scholar.google.com/citations?hl=en&user=WQkHnkMAAAAJ
ORCID iD: orcid.org/0000-0001-9225-4910
Linkedin: https://www.linkedin.com/in/moritz-senger-0859a42b1/
Bluesky: @moritzsenger.bsky.social
Twitter: twitter.com/MoritzSenger
Research Gate: researchgate.net/profile/Moritz_Senger
Keywords
- catalysis
- photocatalysis
- hydrogenase
- nitrogenase
- time resolved spectroscopy and structure determination
- infrared spectroscopy spectroscopy
Biography
2024 Principal Investigator
Biochemistry, Department of Chemistry, Bio Medical Centre (BMC), Uppsala Universitet, Sweden
2022 – 2024 Postdoctoral Researcher
Biophysical and Bioinorganic Chemistry, Molecular Biomimetics (Prof. Berggren), Department of Chemistry, Ångström Laboratory, Uppsala Universitet, Sweden
2020 –2022 Postdoctoral Researcher
Physical Chemistry (Prof. Hammarström), Department of Chemistry, Ångström, Uppsala Universitet, Sweden
2018 – 2019 Postdoctoral Researcher
Molecular Biophysics, Department of Physics, Freie Universität Berlin, Germany
2018 PhD in Physics
Molecular Biophysics (Prof. Heberle), Department of Physics, Freie Universität Berlin, Germany
Research
Time-resolved spectroscopy and structure determination of [FeFe]-hydrogenases and nitrogenases inspiring green hydrogen and sustainable fertilizer production
Media
https://blogs.rsc.org/cc/2024/09/13/chemcomm-milestones-moritz-senger/
Publications
Selection of publications
Part of Physical Chemistry, Chemical Physics - PCCP, p. 9864-9875, 2025
- DOI for Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Download full text (pdf) of Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Part of Chemical Communications, p. 10914-10917, 2024
- DOI for Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
- Download full text (pdf) of Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Minimal and hybrid hydrogenases are active from archaea
Part of Cell, 2024
- DOI for Minimal and hybrid hydrogenases are active from archaea
- Download full text (pdf) of Minimal and hybrid hydrogenases are active from archaea
Part of ACS Catalysis, p. 10435-10446, 2023
- DOI for Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
- Download full text (pdf) of Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
Structural basis for bacterial energy extraction from atmospheric hydrogen
Part of Nature, p. 541-547, 2023
- DOI for Structural basis for bacterial energy extraction from atmospheric hydrogen
- Download full text (pdf) of Structural basis for bacterial energy extraction from atmospheric hydrogen
Part of ACS Sustainable Chemistry and Engineering, p. 10760-10767, 2022
- DOI for Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
- Download full text (pdf) of Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
Part of Chemical Communications, p. 7184-7187, 2022
- DOI for Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
- Download full text (pdf) of Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
Recent publications
Part of Physical Chemistry, Chemical Physics - PCCP, p. 9864-9875, 2025
- DOI for Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Download full text (pdf) of Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
Part of Journal of the American Chemical Society, p. 4654-4666, 2025
- DOI for Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
- Download full text (pdf) of Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Part of Chemical Communications, p. 10914-10917, 2024
- DOI for Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
- Download full text (pdf) of Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Minimal and hybrid hydrogenases are active from archaea
Part of Cell, 2024
- DOI for Minimal and hybrid hydrogenases are active from archaea
- Download full text (pdf) of Minimal and hybrid hydrogenases are active from archaea
Part of ACS Catalysis, p. 9476-9486, 2023
- DOI for Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
- Download full text (pdf) of Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
All publications
Articles in journal
Part of Physical Chemistry, Chemical Physics - PCCP, p. 9864-9875, 2025
- DOI for Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Download full text (pdf) of Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
Part of Journal of the American Chemical Society, p. 4654-4666, 2025
- DOI for Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
- Download full text (pdf) of Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Part of Chemical Communications, p. 10914-10917, 2024
- DOI for Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
- Download full text (pdf) of Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Minimal and hybrid hydrogenases are active from archaea
Part of Cell, 2024
- DOI for Minimal and hybrid hydrogenases are active from archaea
- Download full text (pdf) of Minimal and hybrid hydrogenases are active from archaea
Part of ACS Catalysis, p. 9476-9486, 2023
- DOI for Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
- Download full text (pdf) of Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
Part of ACS Catalysis, p. 10435-10446, 2023
- DOI for Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
- Download full text (pdf) of Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
Structural basis for bacterial energy extraction from atmospheric hydrogen
Part of Nature, p. 541-547, 2023
- DOI for Structural basis for bacterial energy extraction from atmospheric hydrogen
- Download full text (pdf) of Structural basis for bacterial energy extraction from atmospheric hydrogen
Part of ACS Sustainable Chemistry and Engineering, p. 10760-10767, 2022
- DOI for Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
- Download full text (pdf) of Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
Part of Chemical Science, p. 11058-11064, 2022
- DOI for Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
- Download full text (pdf) of Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
Part of Chemical Communications, p. 7184-7187, 2022
- DOI for Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
- Download full text (pdf) of Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
Part of Inorganic Chemistry, p. 10036-10042, 2022
Part of Journal of the American Chemical Society, p. 13600-13611, 2022
- DOI for Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
- Download full text (pdf) of Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
Part of Physiologia Plantarum, p. 555-567, 2021
- DOI for Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
- Download full text (pdf) of Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
Part of Dalton Transactions, p. 3641-3650, 2021
- DOI for Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
- Download full text (pdf) of Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
Part of Chemical Science, p. 12789-12801, 2020
- DOI for Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
- Download full text (pdf) of Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
Part of Journal of Biological Inorganic Chemistry, p. 777-788, 2020
- DOI for [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
- Download full text (pdf) of [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
Current State of [FeFe]-Hydrogenase Research: Biodiversity and Spectroscopic Investigations
Part of ACS Catalysis, p. 7069-7086, 2020