Göran Frenning

Effect of amino acids on the compaction behavior and stability of spray-dried trypsin/lactose powder

Zhang, Chengqian; Frenning, Göran; Van De Weert, Marco; Bjerregaard, Simon et al.

Part of European Journal of Pharmaceutical Sciences, 2026

DOI for Effect of amino acids on the compaction behavior and stability of spray-dried trypsin/lactose powder
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Complex carrier particles for respiratory drug delivery analysed with sequentially built DEM-simulation models

Wostry, Melvin; Frenning, Göran; Scherliess, Regina

Part of International Journal of Pharmaceutics, 2025

The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering

Gråsjö, Johan; Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran et al.

Part of Powder Technology, 2025

Compaction behavior of freeze-dried and spray-dried trypsin/lactose particulate systems

Zhang, Chengqian; Frenning, Göran; Radeke, Carmen; Lind, Johan Ulrik et al.

Part of Powder Technology, 2024

A mean-strain estimate for plastic particles intended for distinct-particle simulations at high relative density

Frenning, Göran

Part of Computer Methods in Applied Mechanics and Engineering, 2024

Mechanical characterization of tablets using post compression in-die cyclic loading

Marinaki, Marilena; Persson, Ann-Sofie; Frenning, Göran

Part of Powder Technology, 2024

Influence of particle diameter on aerosolization performance and release of budesonide loaded mesoporous silica particles

van der Zwaan, Ires; Pilkington, Georgia A.; Frenning, Göran; Ekström, Mikael et al.

Part of European Journal of Pharmaceutical Sciences, 2024

Single-particle fabric tensors for assemblies of spherical particles

Frenning, Göran

Part of Computer Methods in Applied Mechanics and Engineering, 2024

Segregation in inhalable powders: Quantification of the effect of vibration on adhesive mixtures

Sarangi, Sohan; Simonsson, Anna; Frenning, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 107-119, 2023

On the thermodynamic consistency of the Drucker-Prager Cap model: Modification of the plastic potential and analysis of unloading

Frenning, Göran

Part of Powder Technology, 2023

Engineered microparticles of hyaluronic acid hydrogel for controlled pulmonary release of salbutamol sulphate

Nikjoo, Dariush; van der Zwaan, Ires; Rudén, Jonas; Frenning, Göran

Part of International Journal of Pharmaceutics, 2023

A Voronoi strain-based method for granular materials and continua

Frenning, Göran

Part of Computational particle mechanics, p. 427-443, 2023

A new modelling approach for dissolution of polydisperse powders

van der Zwaan, Ires; Frenning, Göran

Part of International Journal of Pharmaceutics, 2023

Effective friction in adhesive mixtures intended for inhalation: Simulation of oblique impact of adhesive units

Sarangi, Sohan; Frenning, Göran

Part of Powder Technology, 2023

Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran; Gråsjö, Johan

Part of European journal of pharmaceutics and biopharmaceutics, p. 1-10, 2022

Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, 2022

Characterization of Membrane-Type Dissolution Profiles of Clinically Available Orally Inhaled Products Using a Weibull Fit and a Mechanistic Model

van der Zwaan, Irès; Franek, Frans; Fransson, Rebecca; Tehler, Ulrika et al.

Part of Molecular Pharmaceutics, p. 3114-3124, 2022

Towards a macroscopically consistent discrete method for granular materials: Delaunay strain-based formulation

Frenning, Göran

Part of COMPUTATIONAL PARTICLE MECHANICS, p. 1105-1118, 2022

Hyaluronic Acid Hydrogels for Controlled Pulmonary Drug Delivery-A Particle Engineering Approach

Nikjoo, Dariush; van der Zwaan, Ires; Brülls, Mikael; Tehler, Ulrika et al.

Part of Pharmaceutics, 2021

Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran

Part of Pharmaceutics, 2021

Effect of carrier size and mechanical properties on adhesive unit stability for inhalation: A numerical study

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Part of Powder Technology, p. 230-239, 2021

Effect of fine particle shape on the stability and performance of adhesive mixtures intended for inhalation

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Part of Powder Technology, p. 299-305, 2021

On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, 2021

Model for the Analysis of Membrane-Type Dissolution Tests for Inhaled Drugs

Frenning, Göran; van der Zwaan, Ires; Franek, Frans; Fransson, Rebecca et al.

Part of Molecular Pharmaceutics, p. 2426-2434, 2020

Numerical modeling of collision of adhesive units: Stability and mechanical properties during handling

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Part of Chemical Engineering Science: X, 2020

Nanoscale characterization of PEGylated phospholipid coatings formed by spray drying on silica microparticles

An, Junxue; Forchheimer, Daniel; Savmarker, Jonas; Brulls, Mikael et al.

Part of Journal of Colloid and Interface Science, p. 92-100, 2020

Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 148-160, 2019

Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Jonsson, Henrik; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 74-81, 2019

DOI for Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Jonsson, Henrik; Öhman-Mägi, Caroline; Alderborn, Göran; Isaksson, Per et al.

Part of International Journal of Pharmaceutics, p. 130-137, 2019

DOI for Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Nordström, Josefina; Alderborn, Göran; Frenning, Göran

Part of International Journal of Pharmaceutics, p. 120-131, 2018

DOI for Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 143-156, 2018

DOI for Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

Frenning, Göran; Ahnfelt, Emelie; Sjögren, Erik; Lennernäs, Hans

Part of International Journal of Pharmaceutics, p. 274-281, 2017

Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions

Jonsson, Henrik; Gråsjö, Johan; Frenning, Göran

Part of Powder Technology, p. 347-355, 2017

Peptide loaded microgels as antimicrobial surface coatings

Nyström, Lina; Nordström, Randi; Frenning, Göran; Saunders, Brian et al.

Part of Abstracts of Papers of the American Chemical Society, 2017

Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression

Jonsson, Henrik; Frenning, Göran

Part of Powder Technology, p. 79-87, 2016

Electrostatic Swelling Transitions in Surface-Bound Microgels

Nyström, Lina; Alvarez-Asencio, Ruben; Frenning, Göran; Saunders, Brian R. et al.

Part of ACS Applied Materials and Interfaces, p. 27129-27139, 2016

DOI for Electrostatic Swelling Transitions in Surface-Bound Microgels

Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Persson, Ann-Sofie; Nordström, Josefina; Frenning, Göran; Alderborn, Göran

Part of Chemical engineering research & design, p. 183-191, 2016

DOI for Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Towards a mechanistic contact model for elastoplastic particles at high relative densities

Frenning, Göran

Part of Finite elements in analysis and design (Print), p. 56-60, 2015

An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model

Persson, Ann-Sofie; Frenning, Göran

Part of Powder Technology, p. 257-264, 2015

An apparatus for confined triaxial testing of single particles

Jonsson, Henrik; Gråsjö, Johan; Nordström, Josefina; Johansson, Niklas et al.

Part of Powder Technology, p. 121-127, 2015

Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions

Frenning, Göran

Part of MethodsX, p. 79-90, 2015

Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

Widenbring, Ronja; Frenning, Göran; Malmsten, Martin

Part of Biomacromolecules, p. 3671-3678, 2014

DOI for Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Mahmoodi, Foad; Klevan, Ingvild; Nordström, Josefina; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 295-299, 2013

Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis

Frenning, Göran

Part of Materials letters (General ed.), p. 365-368, 2013

Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

Mansson, Ronja; Frenning, Göran; Malmsten, Martin

Part of Biomacromolecules, p. 2317-2325, 2013

DOI for Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation

Persson, Ann-Sofie; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 241-250, 2013

The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Part of International Journal of Pharmaceutics, p. 3-12, 2013

An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method

Persson, Ann-Sofie; Frenning, Göran

Part of Powder Technology, p. 249-256, 2012

An experimental evaluation of an effective medium based compaction equation

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 49-55, 2012

Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 283-290, 2011

Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices

Jämstorp, Erik; Strømme, Maria; Frenning, Göran

Part of Journal of Pharmaceutical Sciences, p. 4338-4348, 2011

Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 199-209, 2011

The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis

Frenning, Göran; Gråsjö, Johan; Hansson, Per

Part of AIChE Journal, p. 1402-1408, 2011

A model describing the internal structure of core/shell hydrogels

Gernandt, Jonas; Frenning, Göran; Richtering, Walter; Hansson, Per

Part of Soft Matter, p. 10327-10338, 2011

DOI for A model describing the internal structure of core/shell hydrogels

Effect of lubrication on the distribution of force between spherical agglomerates during compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 69-74, 2010

Compression mechanics of granule beds: A combined finite/discrete element study

Frenning, Göran

Part of Chemical Engineering Science, p. 2464-2471, 2010

Effective Kawakita parameters for binary mixtures

Frenning, Göran; Nordström, Josefina; Alderborn, Göran

Part of Powder Technology, p. 270-275, 2009

DOI for Effective Kawakita parameters for binary mixtures

Implications of regular solution theory on the release mechanism of catanionic mixtures from gels

Bramer, Tobias; Frenning, Göran; Gråsjö, Johan; Edsman, Katarina et al.

Part of Colloids and Surfaces B, p. 214-225, 2009

DOI for Implications of regular solution theory on the release mechanism of catanionic mixtures from gels

An effective-medium analysis of confined compression of granular materials

Frenning, Göran; Mahmoodi, Foad; Nordström, Josefina; Alderborn, Göran

Part of Powder Technology, p. 228-232, 2009

DOI for An effective-medium analysis of confined compression of granular materials

Order and disorder in powder mixtures: Spatial distribution functions as tools to assess powder homogeneity

Mihranyan, Albert; Frenning, Göran; Fransén, Nelly; Welch, Ken et al.

Part of Particle & particle systems characterization, p. 397-405, 2009

DOI for Order and disorder in powder mixtures: Spatial distribution functions as tools to assess powder homogeneity

Ionic motion in polypyrrole-cellulose composites: Trap release mechanism during potentiostatic reduction

Strömme, Maria; Frenning, Göran; Razaq, Aamir; Gelin, Kristina et al.

Part of Journal of Physical Chemistry B, p. 4582-4589, 2009

Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions

Unga, Johan; Tajarobi, Farhad; Norder, Ove; Frenning, Göran et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 260-268, 2009

DOI for Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions

Proton Absorption in As-Synthesized Mesoporous Silica Nanoparticles as a Structure-Function Relationship Probing Mechanism

Strømme, Maria; Atluri, Rambabu; Brohede, Ulrika; Frenning, Göran et al.

Part of Langmuir, p. 4306-4310, 2009

DOI for Proton Absorption in As-Synthesized Mesoporous Silica Nanoparticles as a Structure-Function Relationship Probing Mechanism

Spectral analysis of force fluctuations during probe penetration into cohesive powders

Frenning, Göran; Alderborn, Göran; Kish, Laszlo B.; Mahlin, Denny

Part of Powder Technology, p. 62-67, 2008

DOI for Spectral analysis of force fluctuations during probe penetration into cohesive powders

On the physical interpretation of the Kawakita and Adams parameters derived from confined compression of granular solids

Nordström, Josefina; Welch, Ken; Frenning, Göran; Alderborn, Göran

Part of Powder Technology, p. 424-435, 2008

DOI for On the physical interpretation of the Kawakita and Adams parameters derived from confined compression of granular solids

On the role of granule yield strength for the compactibility of granular solids

Nordström, Josefina; Welch, Ken; Frenning, Göran; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 4807-4814, 2008

DOI for On the role of granule yield strength for the compactibility of granular solids

An efficient finite/discrete element procedure for simulating compression of 3D particle assemblies

Frenning, Göran

Part of Computer methods in applied mechanics and engineering, p. 4266-4272, 2008

DOI for An efficient finite/discrete element procedure for simulating compression of 3D particle assemblies

Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries

Brohede, Ulrika; Valizadeh, Sima; Strømme, Maria; Frenning, Göran

Part of Journal of Pharmaceutical Sciences, p. 3087-3099, 2007

DOI for Percolative drug diffusion from cylindrical matrix systems with unsealed boundaries

Drug release from compacted single inert matrix agglomerates

Fichtner, Frauke; Frenning, Göran; Alderborn, Göran

Part of Journal of Drug Delivery Science and Technology, p. 273-277, 2007

The use of extragranular disintegrants in multiple-unit tablet formulations: effect on compressibility, compactibility and disintegration

Adane, M.; Gebre-Mariam, T; Alderborn, Göran; Frenning, Göran

Part of Journal of drug delivery science and technology, p. 279-284, 2007

Analysis of pharmaceutical powder compaction using multiplicative hyperelasto-plastic theory

Frenning, Göran

Part of Powder Technology, p. 103-112, 2007

DOI for Analysis of pharmaceutical powder compaction using multiplicative hyperelasto-plastic theory

Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

Nilsson, Martin; Frenning, Göran; Gråsjö, Johan; Alderborn, Göran et al.

Part of Journal of Physical Chemistry B, p. 20502-20506, 2006

DOI for Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

A new method for characterizing the release of drugs from single agglomerates

Frenning, Göran; Fichtner, Frauke; Alderborn, Göran

Part of Chemical Engineering Science, p. 3909-3918, 2005

DOI for A new method for characterizing the release of drugs from single agglomerates

Finite element analysis of the release of slowly dissolving drugs from cylindrical matrix systems

Frenning, Göran; Brohede, Ulrika; Strømme, Maria

Part of Journal of Controlled Release, p. 320-329, 2005

DOI for Finite element analysis of the release of slowly dissolving drugs from cylindrical matrix systems

Influence of polymer molecular weight on the solid-state structure of PEG/Monoolein mixtures

Mahlin, D; Unga, J; Ridell, A; Frenning, G et al.

Part of Polymer, p. 12210, 2005

Evolution of distributions and spatial correlations of single-particle forces and stresses during compression of ductile granular materials.

Frenning, Göran; Alderborn, Göran

Part of Phys Rev E Stat Nonlin Soft Matter Phys, 2005

Characterization of the drug release process by investigation of its temperature dependence

Brohede, Ulrika; Frenning, Göran; Strömme, Maria

Part of Journal of Pharmaceutical Sciences, p. 1796-1803, 2004

DOI for Characterization of the drug release process by investigation of its temperature dependence

Solid-state characterisation of PEG 4000/monoolein mixtures

Mahlin, Denny; Ridell, Annika; Frenning, Göran; Engström, Sven

Part of Macromolecules, p. 2665-2667, 2004

DOI for Solid-state characterisation of PEG 4000/monoolein mixtures

A generalized regular singular-point description of low-frequency dielectric responses

Frenning, Göran; Nilsson, Martin; Strømme, Maria

Part of Phys. Rev. B, 2004

Compression behaviour and tablet-forming ability of spray-dried amorphous composite particles.

Berggren, Jonas; Frenning, Göran; Alderborn, Göran

Part of Eur J Pharm Sci, p. 191-200, 2004

Theoretical analysis of the release of slowly dissolving drugs from spherical matrix systems.

Frenning, Göran

Part of J Control Release, p. 109-17, 2004

Theoretical investigation of ion conduction in three-layered ion-conductor systems: Derivation of the isothermal transient ionic current and frequency-dependent impedance

Frenning, Göran; Jonsson, AnnaKarin; Larsson, A.-L.; Strömme, Maria

Part of Journal of Applied Physics, p. 1629, 2003

DOI for Theoretical investigation of ion conduction in three-layered ion-conductor systems: Derivation of the isothermal transient ionic current and frequency-dependent impedance

Drug release modeled by dissolution, diffusion, and immobilization

Frenning, Göran; Strømme, Maria

Part of International Journal of Pharmaceutics, p. 137-145, 2003

DOI for Drug release modeled by dissolution, diffusion, and immobilization

A new method for characterizing the release of drugs from tablets in low liquid surroundings

Frenning, Göran; Ek, Ragnar; Strømme, Maria

Part of Journal of Pharmaceutical Sciences, p. 776-784, 2002

DOI for A new method for characterizing the release of drugs from tablets in low liquid surroundings

Theoretical derivation of the isothermal transient ionic current in an ion conductor: Migration, diffusion, and space-charge effects

Frenning, Göran; Strömme, Maria

Part of Journal of Applied Physics, p. 5570-5575, 2001

DOI for Theoretical derivation of the isothermal transient ionic current in an ion conductor: Migration, diffusion, and space-charge effects

Dielectric study of thin films of Ta2O5 and ZrO2

Jonsson, AnnaKarin; Frenning, Göran; Nilsson, M; Strømme Mattsson, Maria et al.

Part of IEEE transactions on dielectrics and electrical insulation, p. 648-651, 2001

DOI for Dielectric study of thin films of Ta2O5 and ZrO2

Dielectric and Li transport properties of electron conducting and non-conducting sputtered amorphous Ta2O5 films

Frenning, Göran; Nilsson, M; Westlinder, Jörgen; Niklasson, Gunnar A et al.

Part of Electrochimica Acta, p. 2041-2046, 2001

DOI for Dielectric and Li transport properties of electron conducting and non-conducting sputtered amorphous Ta2O5 films

Li conduction in sputtered amorphous Ta2O5

Frenning, Göran; Engelmark, Fredrik; Niklasson, Gunnar A; Strømme, Maria

Part of Journal of the Electrochemical Society, 2001

DOI for Li conduction in sputtered amorphous Ta2O5

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