Research news
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Promising treatment for rectal cancer
A new treatment for locally advanced rectal cancer shows favourable results in that surgery can sometimes be avoided completely. It also reduces the risk of recurrence. The method has been confirmed as effective in a comprehensive study conducted at IGP and published in eClinicalMedicine. Läs mer -
Genetic signatures provide prognostic information in colorectal cancer
Using a unique collection of genetic and clinical data for colorectal cancer, researchers at IGP revealed genetic new alterations and developed of a new molecular classifier of tumour variants. The finding could lead to improved possibilities for individualised therapies. This is shown in study recently published in the journal Nature. Läs mer -
Lymphoma patients at high risk of infections after diagnosis
Every year, around 100 people are affected by mantle cell lymphoma. A study from IGP shows that these patients are more vulnerable to other diseases and that the risk of infection for this type of patient should therefore be carefully evaluated. The results of have been published in the journal Hemasphere. Läs mer -
Modified cold virus could provide new weapon against cancer
Injections with a genetically modified virus have shown promise against pancreatic cancer in a new study conducted by researchers at IGP, Baylor College of Medicine in Houston, Texas, and Lokon Pharma. In almost all patients, the tumours shrank. Läs mer -
Achilles’ heel for immunotherapy identified in triple-negative breast cancer
In a recent study published in the journal Nature Communications, researchers from IGP show that the gene NEDD8 affects the capacity of cancer cells to develop resistance against immunotherapy. The findings could be used to develop more effective immunotherapies for the cancer form triple-negative breast cancer. Läs mer -
Lower survival for women than men with germ cell tumours
Women who suffer from the ovarian cancer known as germ cell tumours have a worse prognosis than men with the corresponding tumours, i.e. testicular cancer. After five years with the disease, 98 per cent of men were alive, but survival for women was only 85 per cent. This is shown in a new study from IGP and Uppsala University Hospital published in the journal Journal of Internal Medicine. Läs mer -
Quiescent cancer cells potential target for colorectal cancer therapy
For patients with colorectal cancer the tumour often recurs since quiescent cancer cells can escape therapy and start growing again. In a study from IGP, the researchers have discovered a protein that identifies such quiescent cancer cells. This could improve the possibilities to eliminate also these cells and ultimately lead to more effective therapy. Läs mer -
Patients with precursor stage of malignant melanoma show better survival than people in general
Malignant melanoma is the cancer type that shows the largest increase in Sweden. A study from IGP shows that patients with a precursor stage of malignant melanoma have a significantly better survival than the population in general, despite an increased risk of being diagnosed with malignant melanoma. The results have been published in the journal eClinicalMedicine/The Lancet. Läs mer