Biophysics with X-ray Lasers with X-ray Lasers
The research in biophysics revolves around X-ray free-electron lasers, which provide extremely intense and ultrashort X-ray pulses. This opens new possibilities to determine structural information of biomolecules with atomic resolution, using diffraction before destruction. We are studying the ultrafast dynamics, fragmentation and non-thermal heating induced by X-ray free electron lasers.
We use Molecular Dynamics, Quantum Chemistry and Plasma Simulations to study ultrafast dynamics in biomolecules. We are interested in the atomic dynamics and study how to improve single particle imaging using information from fragmentation and orientation. We are working on model development in photon-matter interaction at high X-ray field strengths, complemented with performing experiments at X-ray facilities.
In close collaboration with experiments, we investigate liquid surfaces using synchrotron radiation as well as Molecular Dynamics simulations. We study the solvation properties of inorganic salts close to the water/vapor interface.
The group consists of researchers of varying backgrounds involved in a number of different projects. We are one of the founders of the Biophysics Network at Uppsala University and the Master’s Programme in Biophysics.
Members of the group
Carl Caleman, Nicusor Timneanu, Thomas Mandl, Sebastian Cardoch, Pamela Svensson, Gösta Huldt, Tomas André