Entry requirements

The overview course Chemical Principles IN/Basic chemistry, 10 credit or equivalent.

Learning outcomes

After the course, the student should be able to:

• describe the principlal organisation of prokaryotic and eukaryotic cells.
• identify different classes of biomolecules and explain fundamental relationships between their structure and function.
• describe the principles for the catalytic ability of enzymes and basic experimentally analyse enzyme kinetics.
• describe the structure of biological membranes and explain their role in signal transduction and transport.
• report in general terms for how energy is turned over in living systems.
• describe the most common methods for purifying and analysis of proteins and plan and carry out a protein purification where the most common methods are utilised.
• plan and carry out laboratory work in a correct and safe manner and carry out simpler risk judgements.
• document laboratory work in laboratory session records and account for the results of the laboratory session in writing and orally
• explain the chemical/biological background to everyday biological phenomena and describe how the course content has importance for man, the environment and the society.
• exemplify industrial use of enzymes.

Content

The structure of prokaryotic and eukaryotic cells. Bioenergetics. Biomolecules. The central dogma. Enzyme mechanisms, kinetics and industrial usage. Biological membranes. Signal transduction. Overview of energy metabolism. Methods for purifying and analysis of biomolecules (gel chromatography, ion exchange chromatography. affinity chromatography,electrophoresis).

Instruction

Lectures, problem solving sessions and laboratory work.

Assessment

Written examinations are organised at the end of the course and/or during the course and corresponds to 3 credits. The laboratory sessions including chemistry profile/assignments correspond to 2 credits. To pass final grades it is required that all parts have been assessed passed. The final grade corresponds to a weighted average of the results from the written examination and the laboratory work.