Synthetic Organic Chemistry

5 credits

Syllabus, Bachelor's level, 1KB419

A revised version of the syllabus is available.
Code
1KB419
Education cycle
First cycle
Main field(s) of study and in-depth level
Chemistry G2F, Technology G2F
Grading system
Pass with distinction, Pass with credit, Pass, Fail
Finalised by
The Faculty Board of Science and Technology, 8 March 2016
Responsible department
Department of Chemistry - BMC

Entry requirements

60 credits in science/engineering including 10 credits organic chemistry.

Learning outcomes

After the course, the student should be able to

  • describe synthetical processes relevant to organic-chemical reactions and discuss the mechanism of these reactions
  • discuss stereochemical problems related to chemical transformations
  • correlate the structure of compounds to their reactivity
  • give examples of how the properties of organic compounds , including their reactivity, can influence environmental and economical decisions
  • plan and carry out fundamental organic transformations of significance for organic synthesis, carry out simple risk assessments and in-session laboratory documentation and oral/written presentation of the contents and results of laboratory sessions.

Content

Organic-chemical reactions of industrially and biochemically relevant compound classes: Arenes, esters, alcohols, aldols, carbohydrates, lipids, amino acids, peptides and nucleic acids. Reaction mechanisms to build/degrade carbon compounds. Examples for common reagent within synthetic chemistry (oxidation, reduction, Lewis acids and Lewis bases, Grignard reagents, organolithium reagents). Mechanisms for catalytic reactions: acid-base catalysis, enzymatic catalysis, metal catalysis (also in biological systems). Organic-chemical reactions in water. Comparison between synthesis in biological systems and industrial synthesis. Overview of spectroscopic methods in organic chemistry (UV, IR, MS, NMR).

Instruction

Lectures, problem solving sessions and laboratory work.

Assessment

Written examination (3 credits). The laboratory sessions correspond to 2 credits. The final grade is a weighted sum of the results of the written examination and the laboratory sessions

Other directives

Cannot be included in a degree together with the course Synthetic Organic Chemistry 1KB407

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