Computational Biology and Bioinformatics
What kind of research are we doing?
Research in this programme focuses on computational biology, with an emphasis on structural biology, biochemistry, and bioinformatics. We carry out computational simulation and prediction of macromolecular functions and interactions, as well as the development of novel methods.
Key research areas include biological catalysis, molecular recognition, structure-based drug design, and force field development using machine learning. The programme is recognized as world-leading in several fields and maintains extensive national and international collaborations, including the development of widely used simulation tools and computational models of protein function. We also collaborate closely with the pharmaceutical industry on applied research projects.
Research groups
- Johan Åqvist: (program director): Beräkningsstrukturbiologi och biokemi
- Bengt Persson: (Head of department, delegated FUAP): Medical Bioinformatics
- David van der Spoel: Method development in computational biology, in particular, development of force fields for molecular simulations
- Hugo Gutierrez de Teran: Protein-ligand binding, Membrane receptors
- Jan Komorowski: (senior professor): Bioinformatics
- Jens Carlsson: Structure-based drug design
About us
Head of the programme: Johan Åqvist
Visiting address: Husargatan 3, 752 37 Uppsala
Postal address: Box 596, 751 24 Uppsala, Sweden