Jöns Hilborn group

Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space

Rodler, Agnes; Samanta, Ayan; Goh, Wen-Jun; Hilborn, Jöns et al.

Part of European Polymer Journal, 2024

• DOI for Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space
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Technology platform for facile handling of 3D hydrogel cell culture scaffolds

Pohlit, Hannah; Bohlin, Jan; Katiyar, Neeraj; Hilborn, Jöns et al.

Part of Scientific Reports, 2023

• DOI for Technology platform for facile handling of 3D hydrogel cell culture scaffolds
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An Injectable, Shape-Retaining Collagen Hydrogel Cross-linked Using Thiol-Maleimide Click Chemistry for Sealing Corneal Perforations

Rosenquist, Jenny; Folkesson, Matilde; Höglund, Lisa; Pupkaite, Justina et al.

Part of ACS Applied Materials and Interfaces, p. 34407-34418, 2023

• DOI for An Injectable, Shape-Retaining Collagen Hydrogel Cross-linked Using Thiol-Maleimide Click Chemistry for Sealing Corneal Perforations
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Unveiling extracellular matrix assembly: Insights and approaches through bioorthogonal chemistry

Tavakoli, Shima; Evans, Austin; Oommen, Oommen P.; Creemers, Laura et al.

Part of MATERIALS TODAY BIO, 2023

• DOI for Unveiling extracellular matrix assembly: Insights and approaches through bioorthogonal chemistry
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Exploring the Concept of In Vivo Guided Tissue Engineering by a Single-Stage Surgical Procedure in a Rodent Model

Chamorro, Clara Ibel; Zeiai, Said; Juul, Nikolai; Willacy, Oliver et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for Exploring the Concept of In Vivo Guided Tissue Engineering by a Single-Stage Surgical Procedure in a Rodent Model
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Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model

Samanta, Sumanta; Le Joncour, Vadim; Wegrzyniak, Olivia; Rangasami, Vignesh K. et al.

Part of Advanced Therapeutics, 2022

• DOI for Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model
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Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications

Wang, Shujiang; Tavakoli, Shima; Parvathaneni, Rohith Pavan; Nawale, Ganesh N. et al.

Part of Biomaterials Science, p. 6399-6412, 2022

• DOI for Dynamic covalent crosslinked hyaluronic acid hydrogels and nanomaterials for biomedical applications
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Enzymatic Crosslinked Hydrogels for Biomedical Application

Badali, Elham; Hosseini, Mahshid; Mohajer, Maryam; Hassanzadeh, Sajad et al.

Part of Polymer science, 2021

• DOI for Enzymatic Crosslinked Hydrogels for Biomedical Application

ILC1 drive intestinal epithelial and matrix remodelling

Jowett, Geraldine M.; Norman, Michael D. A.; Yu, Tracy T. L.; Rosell Arevalo, Patricia et al.

Part of Nature Materials, p. 250-259, 2021

• DOI for ILC1 drive intestinal epithelial and matrix remodelling

Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery

Kadekar, Sandeep; Nawale, Ganesh N.; Rangasami, Vignesh K.; Le Joncour, Vadim et al.

Part of Biomaterials Science, p. 3939-3944, 2021

• DOI for Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery
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Click chemistry-based biopolymeric hydrogels for regenerative medicine

Li, Ya; Wang, Xiaonan; Han, Yuanyuan; Sun, Hung-Yu et al.

Part of Biomedical Materials, 2021

• DOI for Click chemistry-based biopolymeric hydrogels for regenerative medicine

Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Rangasami, Vignesh K.; Nawale, Ganesh N.; Asawa, Kenta; Kadekar, Sandeep et al.

Part of Biomacromolecules, p. 1980-1989, 2021

• DOI for Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells
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Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Rangasami, Vignesh K.; Samanta, Sumanta; Parihar, Vijay Singh; Asawa, Kenta et al.

Part of Carbohydrate Polymers, 2021

• DOI for Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Functional properties of low-modulus PMMA bone cements containing linoleic acid

Robo, Céline; Wenner, David; Ubhayasekera, S. J. Kumari A.; Hilborn, Jöns et al.

Part of Journal of Functional Biomaterials, 2021

• DOI for Functional properties of low-modulus PMMA bone cements containing linoleic acid
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Hyaluronan derived nanoparticle for simvastatin delivery: evaluation of simvastatin induced myotoxicity in tissue engineered skeletal muscle

Jones, Julia M.; Player, Darren J.; Samanta, Sumanta; Rangasami, Vignesh K. et al.

Part of Biomaterials Science, p. 302-312, 2020

• DOI for Hyaluronan derived nanoparticle for simvastatin delivery: evaluation of simvastatin induced myotoxicity in tissue engineered skeletal muscle
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Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

Kim, Yang-Hee; Yang, Xia; Shi, Liyang; Lanham, Stuart A. et al.

Part of Nature Communications, 2020

• DOI for Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
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Modulating thiol pK_a promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels

Bermejo-Velasco, Daniel; Azémar, Alice; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Biomacromolecules, p. 1412-1420, 2019

• DOI for Modulating thiol pK_a promotes disulfide formation at physiological pH: An elegant strategy to design disulfide cross-linked hyaluronic acid hydrogels

First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

Bermejo-Velasco, Daniel; Kadekar, Sandeep; Tavares da Costa, Marcus Vinicius; Oommen, Oommen P. et al.

Part of ACS Applied Materials and Interfaces, p. 38232-38239, 2019

• DOI for First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification

Han, Yuanyuan; Qiu, Zhen; Nawale, Ganesh N.; Varghese, Oommen P. et al.

Part of Biosensors & bioelectronics, p. 188-193, 2019

• DOI for MicroRNA detection based on duplex-specific nuclease-assisted target recycling and gold nanoparticle/graphene oxide nanocomposite-mediated electrocatalytic amplification

Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2

Paidikondala, Maruthibabu; Wang, Shujiang; Hilborn, Jöns; Larsson, Sune et al.

Part of ACS Applied Bio Materials, 2019

• DOI for Impact of Hydrogel Cross-Linking Chemistry on the in Vitro and in VivoBioactivity of Recombinant Human Bone Morphogenetic Protein-2

Carbon nanotube doped pericardial matrix derived electroconductive biohybrid hydrogel for cardiac tissue engineering

Roshanbinfar, Kaveh; Mohammadi, Zahra; Mesgar, Abdorreza Sheikh-Mandi; Dehghan, Mohammad Mehdi et al.

Part of Biomaterials Science, p. 3906-3917, 2019

• DOI for Carbon nanotube doped pericardial matrix derived electroconductive biohybrid hydrogel for cardiac tissue engineering

Self-Healing Polymeric Hydrogel Formed by Metal-Ligand Coordination Assembly: Design, Fabrication, and Biomedical Applications

Shi, Liyang; Ding, Pinghui; Wang, Yuzhi; Zhang, Yu et al.

Part of Macromolecular rapid communications, 2019

• DOI for Self-Healing Polymeric Hydrogel Formed by Metal-Ligand Coordination Assembly: Design, Fabrication, and Biomedical Applications

Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels

Wang, Shujiang; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Polymer Chemistry, p. 4322-4327, 2019

• DOI for Influence of ions to modulate hydrazone and oxime reaction kinetics to obtain dynamically cross-linked hyaluronic acid hydrogels
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Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder

Ajalloueian, Fatemeh; Lemon, Greg; Hilborn, Jöns; Chronakis, Ioannis S. et al.

Part of Nature reviews. Urology, p. 155-174, 2018

• DOI for Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder

Injectable hyaluronic acid hydrogels with the capacity for magnetic resonance imaging

Bermejo-Velasco, Daniel; Dou, Weiqiang; Heerschap, Arend; Ossipov, Dmitri A. et al.

Part of Carbohydrate Polymers, p. 641-648, 2018

• DOI for Injectable hyaluronic acid hydrogels with the capacity for magnetic resonance imaging

Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH

Bermejo-Velasco, Daniel; Nawale, Ganesh N.; Oommen, Oommen P.; Hilborn, Jöns et al.

Part of Chemical Communications, p. 12507-12510, 2018

• DOI for Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH
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Non-toxic chemically crosslinked collagen hydrogels for cell delivery

Pupkaite, Justina; Griffith, May; Hilborn, Jöns; Suuronen, Erik et al.

Part of Journal of Molecular and Cellular Cardiology, p. 104, 2018

• DOI for Non-toxic chemically crosslinked collagen hydrogels for cell delivery

Moldable Hyaluronan Hydrogel Enabled by Dynamic Metal–Bisphosphonate Coordination Chemistry for Wound Healing

Shi, Liyang; Yannan, Zhao; Qifan, Xie; Caixia, Fan et al.

Part of Advanced Healthcare Materials, 2018

• DOI for Moldable Hyaluronan Hydrogel Enabled by Dynamic Metal–Bisphosphonate Coordination Chemistry for Wound Healing

A new synthetic granular calcium phosphate compound induces new bone in a sinus lift rabbit model

Trbakovic, Amela; Hedenqvist, Patricia; Mellgren, Torbjörn; Ley, Cecilia et al.

Part of Journal of Dentistry, p. 31-39, 2018

• DOI for A new synthetic granular calcium phosphate compound induces new bone in a sinus lift rabbit model

Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH

Wang, Shujiang; Nawale, Ganesh N.; Kadekar, Sandeep; Oommen, Oommen P. et al.

Part of Scientific Reports, 2018

• DOI for Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH
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Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

Yan, Hongji; Casalini, Tommaso; Hulsart Billström, Gry; Wang, Shujiang et al.

Part of Biomaterials, p. 190-202, 2018

• DOI for Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation

Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Ekdahl, Kristina N; Soveri, Inga; Hilborn, Jöns; Fellström, Bengt et al.

Part of Nature Reviews Nephrology, p. 285-296, 2017

• DOI for Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Bioinspired coupled helical coils for soft tissue engineering of tubular structures: Improved mechanical behavior of tubular collagen type I templates

Janke, H. P.; Bohlin, Jan; Lomme, R. M. L. M.; Mihaila, S. M. et al.

Part of Acta Biomaterialia, p. 234-242, 2017

• DOI for Bioinspired coupled helical coils for soft tissue engineering of tubular structures: Improved mechanical behavior of tubular collagen type I templates

Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering

Roshanbinfar, Kaveh; Hilborn, Jöns; Varghese, Oommen P.; Oommen, Oommen P.

Part of RSC Advances, p. 31980-31988, 2017

• DOI for Injectable and thermoresponsive pericardial matrix derived conductive scaffold for cardiac tissue engineering
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Dynamic Coordination Chemistry Enables Free Directional Printing of Biopolymer Hydrogel

Shi, Liyang; Carstensen, Hauke; Hölzl, Katja; Lunzer, Markus et al.

Part of Chemistry of Materials, p. 5816-5823, 2017

• DOI for Dynamic Coordination Chemistry Enables Free Directional Printing of Biopolymer Hydrogel

Self-Healing Silk Fibroin-Based Hydrogel for Bone Regeneration: Dynamic Metal-Ligand Self-Assembly Approach

Shi, Liyang; Wang, Fanlu; Zhu, Wei; Xu, Zongpu et al.

Part of Advanced Functional Materials, 2017

• DOI for Self-Healing Silk Fibroin-Based Hydrogel for Bone Regeneration: Dynamic Metal-Ligand Self-Assembly Approach

Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

Todeschi, Maria R.; El Backly, Rania M.; Varghese, Oommen P.; Hilborn, Jöns et al.

Part of Regenerative Medicine, p. 525-539, 2017

• DOI for Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Gurav, Deepanjali; Varghese, Oommen P.; Hamad, Osama A.; Nilsson, Bo et al.

Part of Chemical Communications, p. 966-969, 2016

• DOI for Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: Results of a multicentre analysis

Hulsart-Billström, Gry; Dawson, J. I.; Hofmann, S.; Müller, R. et al.

Part of European Cells and Materials, p. 312-322, 2016

• DOI for A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: Results of a multicentre analysis
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PDMS-Based Elastomer Tuned Soft, Stretchable, and Sticky for epidermal electronics

Jeong, Seung Hee; Shou, Zhang; Hjort, Klas; Hilborn, Jöns et al.

Part of Advanced Materials, p. 5830-5836, 2016

• DOI for PDMS-Based Elastomer Tuned Soft, Stretchable, and Sticky for epidermal electronics

Control of growth factor binding and release in bisphosphonate functionalized hydrogels guides rapid diff erentiation of precursor cells in vitro

Kootala, Sujit; Zhang, Yu; Ghalib, Sara; Tolmachev, Vladimir et al.

Part of Biomaterials Science, p. 250-254, 2016

• DOI for Control of growth factor binding and release in bisphosphonate functionalized hydrogels guides rapid diff erentiation of precursor cells in vitro

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Oommen, Oommen Podiyan; Duehrkop, Claudia; Nilsson, Bo; Hilborn, Jöns et al.

Part of ACS Applied Materials and Interfaces, p. 20614-20624, 2016

• DOI for Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

The effect of oligo(trimethylene carbonate) addition on the stiffness of acrylic bone cement

Persson, Cecilia; López, Alejandro; Fathali, Hoda; Hoess, Andreas et al.

Part of Biomatter, 2016

• DOI for The effect of oligo(trimethylene carbonate) addition on the stiffness of acrylic bone cement
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Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction

Ranga, Adrian; Lutolf, Matthias P.; Hilborn, Jöns; Ossipov, Dmitri A.

Part of Biomacromolecules, p. 1553-1560, 2016

• DOI for Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction

Functionalised type-I collagen as a hydrogel building block for bio-orthogonal tissue engineering applications

Ravichandran, R.; Islam, M. M.; Alarcon, E. I.; Samanta, Ayan et al.

Part of Journal of materials chemistry. B, p. 318-326, 2016

• DOI for Functionalised type-I collagen as a hydrogel building block for bio-orthogonal tissue engineering applications

“Smart” drug loaded nanoparticle delivery from a self-healing hydrogel enabled by dynamic magnesium–biopolymer chemistry

Shi, Liyang; Han, Yuanyuan; Hilborn, Jöns; Ossipov, Dmitri

Part of Chemical Communications, p. 11151-11154, 2016

• DOI for “Smart” drug loaded nanoparticle delivery from a self-healing hydrogel enabled by dynamic magnesium–biopolymer chemistry

Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Varghese, Oommen P.; Liu, Jianping; Sundaram, Karthi; Hilborn, Jöns et al.

Part of Biomaterials Science, p. 1310-1313, 2016

• DOI for Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Hyaluronic acid-fibrin interpenetrating double network hydrogelprepared in situ by orthogonal disulfide cross-linking reaction forbiomedical applications

ZHANG, YU; Heher, Philipp; Hilborn, Jöns; Redl, Heinz et al.

Part of Acta Biomaterialia, 2016

Hyaluronic acid-fibrin interpenetrating double network hydrogel prepared in situ by orthogonal disulfide cross-linking reaction for biomedical applications

Zhang, Yu; Heher, Philipp; Hilborn, Jöns; Redl, Heinz et al.

Part of Acta Biomaterialia, p. 23-32, 2016

• DOI for Hyaluronic acid-fibrin interpenetrating double network hydrogel prepared in situ by orthogonal disulfide cross-linking reaction for biomedical applications

Non-invasive in vitro and in vivo monitoring of degradation of fluorescently labeled hyaluronan hydrogels for tissue engineering applications

Zhang, Yu; Rossi, Filippo; Papa, Simonetta; Violatto, Martina Bruna et al.

Part of Acta Biomaterialia, p. 188-198, 2016

• DOI for Non-invasive in vitro and in vivo monitoring of degradation of fluorescently labeled hyaluronan hydrogels for tissue engineering applications