Lindberg group
Metabolic engineering of cyanobacteria
Our research
Our research is focused on genetically modifying the metabolism of cyanobacteria to achieve efficient, carbon-neutral production of fuels and other useful substances.
A particular focus is hydrocarbons produced from cyanobacterial terpenoid biosynthesis. We are working to introduce new genetic constructs into the bacteria using genetic engineering and synthetic biology, and are also investigating the natural metabolism of our model organisms, particularly the pathways that may be useful for the production of hydrocarbons.
Group members
Publications
Tailoring regulatory components for metabolic engineering in cyanobacteria
Part of Physiologia Plantarum, 2024
Metabolic engineering of Synechocystis sp. PCC 6803 for the improved production of phenylpropanoids
Part of Microbial Cell Factories, 2024
Laboratory evolution of Synechocystis sp. PCC 6803 for phenylpropanoid production
Part of Metabolic engineering, p. 27-37, 2023
Part of Microbial Cell Factories, 2023
Part of Bioresource Technology, 2023
Part of Microbial Cell Factories, 2022
- DOI for Expression of phenylalanine ammonia lyases in Synechocystis sp. PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids
- Download full text (pdf) of Expression of phenylalanine ammonia lyases in Synechocystis sp. PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids
Part of Green Chemistry, p. 9602-9619, 2022
Part of Microbial Cell Factories, 2021
- DOI for Production of succinate by engineered strains of Synechocystis PCC 6803 overexpressing phosphoenolpyruvate carboxylase and a glyoxylate shunt
- Download full text (pdf) of Production of succinate by engineered strains of Synechocystis PCC 6803 overexpressing phosphoenolpyruvate carboxylase and a glyoxylate shunt
Part of Physiologia Plantarum, p. 579-590, 2021
- DOI for Photoautotrophic production of renewable ethylene by engineered cyanobacteria: Steering the cell metabolism towards biotechnological use
- Download full text (pdf) of Photoautotrophic production of renewable ethylene by engineered cyanobacteria: Steering the cell metabolism towards biotechnological use
Metabolic engineering of Synechocystis sp. PCC 6803 for improved bisabolene production
Part of Metabolic Engineering Communications, 2021
Doing synthetic biology with photosynthetic microorganisms
Part of Physiologia Plantarum, p. 624-638, 2021
High density cultivation for efficient sesquiterpenoid biosynthesis in Synechocystis sp. PCC 6803
Part of Scientific Reports, 2020
Part of Biotechnology for Biofuels, 2020
Part of Current opinion in chemical biology, p. 69-76, 2020
- DOI for Current processes and future challenges of photoautotrophic production of acetyl-CoA-derived solar fuels and chemicals in cyanobacteria
- Download full text (pdf) of Current processes and future challenges of photoautotrophic production of acetyl-CoA-derived solar fuels and chemicals in cyanobacteria
Part of METABOLIC ENGINEERING COMMUNICATIONS, 2020
Modular engineering for efficient photosynthetic biosynthesis of 1-butanol from CO2 in cyanobacteria
Part of Energy & Environmental Science, p. 2765-2777, 2019
Part of Metabolic engineering, p. 164-177, 2018
- DOI for Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound.
- Download full text (pdf) of Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound.
Part of Metabolic engineering, p. 51-59, 2018
Engineering photoautotrophic carbon fixation for enhanced growth and productivity
Part of Sustainable Energy & Fuels, p. 2583-2600, 2018
Part of Metabolic Engineering Communications, p. 45-53, 2017
Part of Physiologia Plantarum, p. 182-195, 2017
Part of Scientific Reports, 2016
- DOI for Evaluation of promoters and ribosome binding sites for biotechnological applications in the unicellular cyanobacterium Synechocystis sp. PCC 6803
- Download full text (pdf) of Evaluation of promoters and ribosome binding sites for biotechnological applications in the unicellular cyanobacterium Synechocystis sp. PCC 6803
Part of Journal of Biotechnology, p. 1-5, 2016
Part of ACS Synthetic Biology, p. 1270-1278, 2015
Terpenoids and their biosynthesis in cyanobacteria.
Part of Life, p. 269-93, 2015
Production of Squalene in Synechocystis sp. PCC 6803
Part of PLoS ONE, 2014
Part of Applied and Environmental Microbiology, p. 273-276, 2012
Part of Ambio, p. 163-168, 2012
Synthetic Biology in Cyanobacteria: Engineering and Analyzing Novel Functions
Part of Methods in Enzymology, p. 539-579, 2011
Part of Metabolic engineering, p. 70-9, 2010
Part of Plant Physiology, p. 88-99, 2009
Characterization of the hupSL promoter activity in Nostoc punctiforme ATCC 29133
Part of BMC Microbiology, p. 54, 2009
The chloroplast sulfate transport system in the green alga Chlamydomonas reinhardtii.
Part of Planta, p. 951-61, 2008
Part of BMC Biotechnology, p. 73, 2008
Part of Applied and Environmental Microbiology, p. 2137-2145, 2004
A hydrogen-producing, hydrogenase-free mutant strain of Nostoc punctiforme ATCC 29133
Part of International Journal of Hydrogen Energy, p. 1291-1296, 2002
Part of International Journal of Hydrogen Energy, p. 1271-1281, 2002
Hydrogenases and Hydrogen Metabolism of Cyanobacteria
Part of Microbiology and Molecular Biology Reviews, p. 1-20, 2002
Part of FEMS Microbiology Letters, p. 59-64, 2001
hupS and hupL constitute a transcription unit in the cyanobacterium Nostoc sp. PCC 73102
Part of Archives of Microbiology, p. 129-133, 2000