Niccoló De Berardinis

Magnesium-based alloys have gained considerable attention in the scientific field for their potential orthopaedic applications due to their unique combination of properties.

One of the key advantages of magnesium-based alloys is their biodegradability. Unlike traditional metallic implants such as stainless steel or titanium, magnesium alloys degrade over time in the body, eliminating the need for a second surgery for implant removal. This property is particularly beneficial in orthopedic applications where temporary support is needed, such as fracture fixation. Moreover, magnesium-based alloys exhibit: excellent mechanical properties closely resembling those of natural bone and good corrosion resistance in physiological environments, ensuring the long-term stability of implants. Additionally, magnesium is an essential element for biological functions, making magnesium-based alloys compatible with the body's physiological environment. They have been found to promote osteogenesis and angiogenesis, further enhancing the bone healing process.

However, challenges such as rapid degradation rates, potential hydrogen gas evolution during degradation and material biocompatibility need to be addressed to ensure the long-term performance of magnesium-based orthopedic implants. Nevertheless, ongoing research and advancements in alloy design hold promise for the continued development and optimization of magnesium-based alloys for orthopedic applications.