Biomedical Engineering
The Division of Biomedical Engineering is part of the Department of Materials Science and Engineering with research focused on understanding interactions between materials and biological systems.
Welcome to the Division of Biomedical Engineering
The Division of Biomedical Engineering is part of the Department of Materials Science and Technology at the Ångström Laboratory. Our ambition is to foster a dynamic teaching and research environment that is internationally recognized for its excellence in connecting basic research with clinical applications. We conduct research in the development and evaluation of new materials in interaction with biological systems to understand the underlying principles. For us, it is equally important to study the impact of materials on biological processes as well as the impact of biological processes on materials.
Research Themes
Precision Medicine
We realize patient-specific implants through additive manufacturing and research organ-on-chip devices for drug development and basic medical research.
Antimicrobial resistance
We develop methods for rapid diagnostics of antibiotic sensitivity, biomaterials with antibacterial properties and tools to decipher the underlying biological processes for the development of antimicrobial resistance.
Sustainability
We develop resource-efficient manufacturing methods and new advanced analysis tools with a reduced environmental footprint.
Data driven life science
We are developing high-throughput microfluidic systems capable of generating large data sets from single-cell assays and using other large data sets obtained from multimodal monitoring of the parameter space to optimize material fabrication processes and component design.
Research Groups
Research Projects
SciLifeLab UU Local Unit
Customized Microfluidics
ERC Consolidator Grant PHOENIX
Novel microfluidic tools for high-throughput and fully controlled organoid generation
Wallenberg Academy Fellowship
Building a platform to grow “minibrains” in the lab
Wallenberg Foundation "FATE"
Revealing the mechanisms behind the fate of plant cells
FORMAS
On-site diagnostic tools to determine antibiotic susceptibility
Wallenberg Initiative Materials Science for Sustainability (WISE)
Additive Manufacturing. Link coming soon!
Vinnova - Emerging technology solutions in synthetic biology
Droplet microfluidics toolbox for resistance development in bacteria
Biomedical Engineering Seminar Series at the Ångström Laboratory
This seminar series is brought to you by the Division of Biomedical Engineering, Dept. Materials Science and Engineering and MedTech Science & Innovation Centre, with the aim of bringing together people at UU and beyond with an interest in biomedical engineering and to share news on the research that is going on across the university in this area.
Education in Biomedical Engineering
Biomedical Engineering is a rapidly evolving, interdisciplinary field of research. At the Division, we offer a comprehensive scientific education, with courses at the bachelor’s, master’s and doctoral level.
Information about courses in the department can be found in the student entrance
PhD Courses
- Acoustofluidics, FTN0189
Credits: 3.5 hp
Contact: Maria Tenje
- Biological characterization of biomaterials
Credits: 5 hp
Contact: Natalia Ferraz
- Electrical measurements for biomedical applications
Credits: 4 hp
Contact: Sofia Johansson
- Introduction to BioMEMS, FTN0027
Credits: 5 hp
Contact: Maria Tenje
- Review Article Writing
Credits: 2.5/5 hp
Contact: Maria Tenje
- Writing and Reviewing in Biomedical Engineering, FTN0385/FTN0386
Credits: 1.5/3 hp
Contact: Maria Tenje and Sofia Johansson
Master's Projects
If you are interested in doing your Master's thesis with us, please send your CV and a short email listing your research interests to: cecilia.persson@angstrom.uu.se or maria.tenje@angstrom.uu.se.
Group Members
Professors
Project Coordinators
Researchers
Shashank Ramesh Babu
Postdoc (BMS)
- Shashank's profile
PhD Students
Publications
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2024
Part of Journal of materials science. Materials in medicine, 2024
Advanced materials provide solutions towards a sustainable world
Part of Nature Materials, p. 160-161, 2024
Part of Advanced Materials Technologies, 2024
- DOI for A perfusable multi-hydrogel vasculature on-chip engineered by 2-photon 3D printing and scaffold molding to improve microfabrication fidelity in hydrogels
- Download full text (pdf) of A perfusable multi-hydrogel vasculature on-chip engineered by 2-photon 3D printing and scaffold molding to improve microfabrication fidelity in hydrogels
Part of Computer Methods and Programs in Biomedicine, 2024
Part of Materials Today Communications, 2024
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2024
Size-related variability of oxygen consumption rates in individual human hepatic cells
Part of Lab on a Chip, 2024
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2024
Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial properties
Part of Journal of the European Ceramic Society, p. 4260-4271, 2024
Part of Ceramics International, p. 30690-30698, 2024
Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis
Part of Advanced Functional Materials, 2024
Part of MICROSYSTEMS & NANOENGINEERING, 2024
- DOI for Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system
- Download full text (pdf) of Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system
Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity
Part of Advanced Materials Interfaces, 2023
2023
An improved trabecular bone model based on Voronoi tessellation
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2023
Round-robin testing of commercial two-photon polymerization 3D printers
Part of Additive Manufacturing, 2023
Technology platform for facile handling of 3D hydrogel cell culture scaffolds
Part of Scientific Reports, 2023
Effects of N/Si ratio on mechanical properties of amorphous silicon nitride coating
Part of Materials Research Express, 2023
Fully 3D-printed PVDF-TrFE based piezoelectric devices with PVDF-TrFE-rGO composites as electrodes
Part of Micro and Nano Engineering, 2023
Part of Mathematical Biosciences and Engineering, p. 6273-6293, 2023
- DOI for The porous cantilever beam as a model for spinal implants: Experimental, analytical and finite element analysis of dynamic properties
- Download full text (pdf) of The porous cantilever beam as a model for spinal implants: Experimental, analytical and finite element analysis of dynamic properties
Quasi-static and dynamic mechanical properties of a low-modulus bone cement for spinal applications
Part of Open Research Europe, 2023
Part of Biomaterials Science, p. 3144-3158, 2023
- DOI for Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
- Download full text (pdf) of Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
SiNx Coating Deposition on CoCr by Plasma-Enhanced Chemical Vapor Deposition
Part of Biomedical Materials & Devices, p. 376-383, 2023
Photophysiological response of Symbiodiniaceae single cells to temperature stress
Part of The ISME Journal, p. 2060-2064, 2022
Confocal imaging dataset to assess endothelial cell orientation during extreme glucose conditions
Part of Scientific Data, 2022
Composite poly(L-lactic acid) - ceramic structures for fully degradable cranial implants
Part of Transactions on Additive Manufacturing Meets Medicine, 2022
Part of Materials Today Bio, 2022
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2022
Part of RSC Advances, p. 30135-30144, 2022
Biocompatibility of a Zr-Based Metallic Glass Enabled by Additive Manufacturing
Part of ACS Applied Bio Materials, p. 5741-5753, 2022
Part of ACS Omega, p. 908-920, 2022
Microfluidics platform for studies of peptide - polyelectrolyte interaction
Part of International Journal of Pharmaceutics, 2022
Part of Materials Today Bio, 2022
- DOI for A microfluidic-based approach to investigate the inflammatory response of macrophages to pristine and drug-loaded nanostructured hydroxyapatite
- Download full text (pdf) of A microfluidic-based approach to investigate the inflammatory response of macrophages to pristine and drug-loaded nanostructured hydroxyapatite
Part of Ceramics International, p. 31449-31460, 2022
An ex-vivo model for the biomechanical assessment of cement discoplasty
Part of Frontiers in Bioengineering and Biotechnology, 2022
Part of Injury, p. 1858-1866, 2022
- DOI for A new bone adhesive candidate- does it work in human bone?: An ex-vivo preclinical evaluation in fresh human osteoporotic femoral head bone
- Download full text (pdf) of A new bone adhesive candidate- does it work in human bone?: An ex-vivo preclinical evaluation in fresh human osteoporotic femoral head bone
A combined experimental and numerical method to estimate the elastic modulus of single trabeculae
Part of Journal of The Mechanical Behavior of Biomedical Materials, 2022
Part of Frontiers in Bioengineering and Biotechnology, 2022
Part of Polymers, 2022
Bioactive Silicon Nitride Implant Surfaces with Maintained Antibacterial Properties
Part of Journal of Functional Biomaterials, 2022
Part of Biomaterials Science, p. 3757-3769, 2022
- DOI for Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium
- Download full text (pdf) of Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium
Self-Assembly of Nanodiamonds and Plasmonic Nanoparticles for Nanoscopy
Part of Biosensors, 2022
Integrated cooling system for microfluidic PDMS devices used in biological microscopy studies
Part of Journal of Micromechanics and Microengineering, 2022
Low-Modulus PMMA Has the Potential to Reduce Stresses on Endplates after Cement Discoplasty
Part of Journal of Functional Biomaterials, 2022
Part of Materials, 2022
- DOI for An Enhanced Understanding of the Powder Bed Fusion-Laser Beam Processing of Mg-Y-3.9wt%-Nd-3wt%-Zr-0.5wt% (WE43) Alloy through Thermodynamic Modeling and Experimental Characterization
- Download full text (pdf) of An Enhanced Understanding of the Powder Bed Fusion-Laser Beam Processing of Mg-Y-3.9wt%-Nd-3wt%-Zr-0.5wt% (WE43) Alloy through Thermodynamic Modeling and Experimental Characterization
Part of Scientific Reports, 2021
Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases
Part of Cardiovascular Research, p. 2742-2754, 2021
Part of ACS Biomaterials Science & Engineering, p. 2926-2948, 2021
Binary acoustic trapping in a glass capillary
Part of Journal of Physics D, 2021
Theses
- Federico Cantoni, PhD, 2023, "Fabrication advances of microvasculature models on-chip"
- Lulu Wu, PhD, 2023, "Development of Nanocellulose Materials for Nano-filtration and Microfluidic Cell Culture"
- Abdul Raouf Atif, PhD, 2023, "Evaluation of Biological Biomaterial Properties using Microfluidic Systems"
- Sarah-Sophia Carter, PhD, 2022 "Exploring microfluidics as a tool to study cell-biomaterial interactions"
- Ana María Porras Hernández, PhD, 2022 "Micropatterning of hyaluronic acid hydrogels for in vitro models"
- Zhenhua Liu, PhD, 2022, "Droplet acoustofluidics for biochemical applications"
- Charlotte Skjöldebrand, PhD, 2022 "Silicon nitride based coatings for biomedical implants"
- Ana María Porras Hernández, Licentiate, 2022 "Chemical micropatterning of hyaluronic acid hydrogels for brain endothelial in vitro cell studies"
Contact Us
You are welcome to visit us at the Ångström laboratory, Lägerhyddsvägen 1, Uppsala. We are situated on Floor 2, Houses 2 & 3
- Maria Tenje, Head of Division & EMBLA Group Leader
- Cecilia Persson, Deputy Head of Division & BMS Leader
- Karin Magnusson, Division & EMBLA group Project Coordinator
- Alexandra Davydova, BMS group Project Coordinator
- Sara Rudqwist, Financial Administrator
Contact Us
You're welcome to contact the Division of Biomedical Engineering
You are welcome to visit us at the Ångström laboratory, Lägerhyddsvägen 1, Uppsala. We are situated on Floor 2, Houses 2 & 3.
- Maria Tenje, Head of Division & EMBLA Group Leader
- Cecilia Persson, Deputy Head of Division & BMS Leader
- Karin Magnusson, Division & EMBLA group Project Coordinator
- Alexandra Davydova, BMS group Project Coordinator
- Sara Rudqwist, Financial Administrator