Molecular Biology and Genetics
Syllabus, Bachelor's level, 1BG113
- Code
- 1BG113
- Education cycle
- First cycle
- Main field(s) of study and in-depth level
- Biology G1F
- Grading system
- Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
- Finalised by
- The Faculty Board of Science and Technology, 10 April 2015
- Responsible department
- Biology Education Centre
Entry requirements
Evolution and Diversity of Organisms, 10 credits, and Professional Qualifications in Biology and the Scientific Method, 5 credits.
Learning outcomes
After the course, the student should be able to:
- account for structure, formation and function of DNA, RNA and proteins
- describe the principles of gene regulation in prokaryotic and eukaryotic cells
- describe the consequences of different types of mutations and DNA-repair systems
- describe the cell cycle, Mendelian genetics, family trees, recombination, restriction enzymes, molecular cloning, DNA-sequencing, and PCR
- use some and understand several modern molecular methods to elucidate molecular and genetic questions
- critically analyse, evaluate and compile results from laboratory exercises
- reason about ethical aspects of genetics.
Content
The course is an introduction to molecular biology and genetics and methods used within these fields. The subject content is the following.
The structure of the genome: chromosomes, chromosomal structure, and extrachromosomal inheritance. The molecular basis of transmission of genetic information: nucleic acids and proteins. DNA replication, DNA repair, mutations, recombination, transposition, transcription, and translation. Examples of gene regulation. Inheritance of genetic information : meiosis, sexual reproduction and classical genetics and transfer of DNA between bacteria. Gene technology: restriction mapping, genetic libraries, cloning, gene expressions to overproduce proteins of interest, DNA/RNA-sequencing, PCR.
The possibilities, limitations and ethics of gene technology are discussed.
Instruction
The teaching is in the form of lectures, laboratory practicals, and exercises in problem solving.
Participation in the laboratory exercises and some other sessions is compulsory.
Assessment
Two written tests: Molecular Biology (4 credits), Genetics (4 credits) and practical parts (laboratory exercises and reports) 2 credits.
Other directives
The course is part of a course package and can only be taken concurrently with the course 1BG112 Microbiology with Infection Biology 5 credits. Students cannot simultaneously be credited with 1BG101 Genetics and Genetic Engineering 15 credits or 1BG111 Genetics and Genetic Engineering 10 credits.
Reading list
- Reading list valid from Autumn 2021
- Reading list valid from Autumn 2020, version 2
- Reading list valid from Autumn 2020, version 1
- Reading list valid from Autumn 2019
- Reading list valid from Autumn 2015
- Reading list valid from Autumn 2014
- Reading list valid from Autumn 2013, version 2
- Reading list valid from Autumn 2013, version 1