Protein Biotechnology

10 credits

Syllabus, Master's level, 1KB768

A revised version of the syllabus is available.
Code
1KB768
Education cycle
Second cycle
Main field(s) of study and in-depth level
Applied Biotechnology A1N, Chemistry A1N, Technology A1N
Grading system
Pass with distinction, Pass with credit, Pass, Fail
Finalised by
The Faculty Board of Science and Technology, 9 March 2017
Responsible department
Department of Chemistry - Ångström

Entry requirements

120 credits including Methods in Biotechnology. Technology of Process Modelling is recommended.

Learning outcomes

The aim of this course is advanced knowledge about protein production on different scales, especially large-scale production, in the biotechnology industry.

After completing this course the student should be able to:

  • Describe from start to finish the entire process of of protein production on different scales, including large-scale industrial production, that fulfils the quality requirements from both industry and regulations from governmental agencies (GLP,GMP)
  • Use a bioreactor in different ways to produce proteins
  • Perform of protein purification with regard to molecular properties and demands placed on product purity
  • Design purification methods for protiens with respect to starting material and production scale
  • Master and rationally select different methods for characterisation of proteins, with consideration to product requirements
  • Critically examine large scale industrial protein production processesand present the results orally.

Content

Cell culturing bioreactors. Preparative scale protein purification and analysis . Protein characterisation by modern bioanalytical tools. GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice). Laws and regulations.Examination of large scale industrial protein production processes. Site visit at a biotechnology company.

Instruction

Instructions are in the form of lectures, seminars, laboratory practicals and a group assignment with oral presentations. Communication training within selected profile areas is integrated with the course components.

Assessment

A written test at the end of the course, and/or during the course, corresponding to 5 credits. Laboratory practicals and demonstrations, oral and written presentations of laboratory reports, and oral presentationof the group assignment t correspond to 5 credits in total. The final grade represents a weighted total of these components.

Other directives

Cannot be counted towards the degree together with 1MB572 Protein biotechnology I, 1MB573 Protein biotechnology II, 1KB761 Protein biotechnology and 1KB762 Protein biotechnology.

No reading list found.

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