Ulf Bondesson

Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Sjolund, Marie; Rosendal, Thomas; Wallgren, Per; Pringle, Maerit et al.

Ingår i Acta Veterinaria Scandinavica, 2025

• DOI för Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs
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Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI för Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
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A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of chromatography. B, 2023

• DOI för A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
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Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Ferrari, Desiree; Lundgren, Sandra; Holmberg, Johanna; Edner, Anna et al.

Ingår i Theriogenology, s. 59-68, 2022

• DOI för Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Metabolites, 2021

• DOI för Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control
• Ladda ner fulltext (pdf) av Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Sjolund, Marie; Rosendal, Thomas; Wallgren, Per; Pringle, Maerit et al.

Ingår i Acta Veterinaria Scandinavica, 2025

• DOI för Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs
• Ladda ner fulltext (pdf) av Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI för Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
• Ladda ner fulltext (pdf) av Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Journal of chromatography. B, 2023

• DOI för A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
• Ladda ner fulltext (pdf) av A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Ferrari, Desiree; Lundgren, Sandra; Holmberg, Johanna; Edner, Anna et al.

Ingår i Theriogenology, s. 59-68, 2022

• DOI för Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions

Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Ingår i Metabolites, 2021

• DOI för Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control
• Ladda ner fulltext (pdf) av Investigation of Equine In Vivo and In Vitro Derived Metabolites of the Selective Androgen Receptor Modulator (SARM) ACP-105 for Improved Doping Control

Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study

Akhter, Tansim; Wikström, Gerhard; Larsson, Marita; Bondesson, Ulf et al.

Ingår i European Journal of Obstetrics, Gynecology, and Reproductive Biology, s. 288-293, 2021

• DOI för Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with/without preeclampsia: A group comparative study
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Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

Strom, L.; Dalin, F.; Domberg, M.; Stenlund, C. et al.

Ingår i BMC Veterinary Research, 2021

• DOI för Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility
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Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

Askar, Raad; Fredriksson, Elin; Manell, Elin; Hedeland, Mikael et al.

Ingår i BMC Veterinary Research, 2020

• DOI för Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits
• Ladda ner fulltext (pdf) av Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis

Ekstrand, Carl; Bondesson, Ulf; Giving, Ellen; Hedeland, Mikael et al.

Ingår i Acta Veterinaria Scandinavica, 2019

• DOI för Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis
• Ladda ner fulltext (pdf) av Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis

Plasma l-arginine levels distinguish pulmonary arterial hypertension from left ventricular systolic dysfunction

Sandqvist, Anna; Schneede, Jörn; Kylhammar, David; Henrohn, D et al.

Ingår i Heart and Vessels, s. 255-263, 2018

• DOI för Plasma l-arginine levels distinguish pulmonary arterial hypertension from left ventricular systolic dysfunction
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Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation

Lundgren, Jakob; Sandqvist, Anna; Hedeland, Mikael; Bondesson, Ulf et al.

Ingår i Scandinavian Cardiovascular Journal, s. 196-204, 2018

• DOI för Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation

Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with and without preeclampsia

Akhter, Tansim; Wikström, Gerhard; Larsson, Margareta; Bondesson, Ulf et al.

Ingår i Atherosclerosis, 2018

• DOI för Dimethylarginines correlate to common carotid artery wall layer dimensions and cardiovascular risk factors in pregnant women with and without preeclampsia

Cetirizine per os: exposure and antihistamine effect in the dog

Ekstrand, Carl; Ingvast-Larsson, Carina; Bondesson, Ulf; Hedeland, Mikael et al.

Ingår i Acta Veterinaria Scandinavica, 2018

• DOI för Cetirizine per os: exposure and antihistamine effect in the dog
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Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Hansson, Annelie; Knych, Heather; Stanley, Scott; Berndtson, Emma et al.

Ingår i Journal of chromatography. B, s. 91-98, 2018

• DOI för Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'"

Dubbelboer, Ilse R; Lilienberg, Elsa; Karalli, Amar; Axelsson, Rimma et al.

Ingår i Molecular Pharmaceutics, s. 336-340, 2018

• DOI för Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'"

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Garg, Neeraj; Hansson, Annelie; Knych, Heather K.; Stanley, Scott D. et al.

Ingår i Organic and biomolecular chemistry, s. 698-702, 2018

• DOI för Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry

Hansson, Annelie; Thevis, Mario; Cox, Holly; Miller, Geoff et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, s. 228-236, 2017

• DOI för Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses

Knych, Heather K.; Stanley, Scott D.; McKemie, Dan S.; Arthur, Rick M. et al.

Ingår i Drug Testing and Analysis, s. 1392-1399, 2017

• DOI för Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses

Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS

Salomonsson, Matilda L.; Bondesson, Ulf; Hedeland, Mikael

Ingår i Drug Testing and Analysis, s. 935-941, 2017

• DOI för Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS

Nickel in equine sports drug testing - pilot study results on urinary nickel concentrations

Thevis, M.; Machnik, M.; Schenk, I.; Krug, O. et al.

Ingår i Rapid Communications in Mass Spectrometry, s. 982-984, 2016

• DOI för Nickel in equine sports drug testing - pilot study results on urinary nickel concentrations

Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

Ingår i Rapid Communications in Mass Spectrometry, s. 833-842, 2016

• DOI för Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry

A quantitative approach to analysing cortisol response in the horse

Ekstrand, C.; Ingvast-Larsson, C.; Olsen, L.; Hedeland, Mikael et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 255-263, 2016

• DOI för A quantitative approach to analysing cortisol response in the horse

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization

Salomonsson, Matilda Lampinen; Fredriksson, Elisabeth; Alfjorden, Anders; Hedeland, Mikael et al.

Ingår i Toxicology reports, s. 1473-1481, 2015

• DOI för Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization

Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension

Sandqvist, Anna; Henrohn, Dan; Egeröd, Hanna; Hedeland, Mikael et al.

Ingår i European Journal of Clinical Pharmacology, s. 1165-1173, 2015

• DOI för Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension

A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry

Rydevik, Axel; Hansson, Annelie; Hellqvist, Anna; Bondesson, Ulf et al.

Ingår i Drug Testing and Analysis, s. 626-633, 2015

• DOI för A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry

Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

Ingår i Drug Testing and Analysis, s. 673-683, 2015

• DOI för Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes

Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate

Ekstrand, C.; Bondesson, Ulf; Gabrielsson, J.; Hedeland, Mikael et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 235-242, 2015

• DOI för Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate

Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing

Thevis, Mario; Lagojda, Andreas; Kuehne, Dirk; Thomas, Andreas et al.

Ingår i Rapid Communications in Mass Spectrometry, s. 991-999, 2015

• DOI för Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing

Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum

Bjornstad, Kristian; Åberg, Annica Tevell; Kalb, Suzanne R.; Wang, Dongxia et al.

Ingår i Analytical and Bioanalytical Chemistry, s. 7149-7161, 2014

• DOI för Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum

Isolation and characterization of a beta-glucuronide of hydroxylated SARM S1 produced using a combination of biotransformation and chemical oxidation

Rydevik, Axel; Lagojda, Andreas; Thevis, Mario; Bondesson, Ulf et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, s. 36-39, 2014

• DOI för Isolation and characterization of a beta-glucuronide of hydroxylated SARM S1 produced using a combination of biotransformation and chemical oxidation

The Effects of Lipiodol and Cyclosporin A on the Hepatobiliary Disposition of Doxorubicin in Pigs

Dubbelboer, Ilse R; Lilienberg, Elsa; Hedeland, Mikael; Bondesson, Ulf et al.

Ingår i Molecular Pharmaceutics, s. 1301-1313, 2014

• DOI för The Effects of Lipiodol and Cyclosporin A on the Hepatobiliary Disposition of Doxorubicin in Pigs

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

Sjögren, Erik; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Ingår i European Journal of Pharmaceutical Sciences, s. 214-223, 2014

• DOI för Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile

Lundahl, Anna; Åberg, Annica Tevell; Bondesson, Ulf; Lennernäs, Hans et al.

Ingår i Xenobiotica, s. 498-510, 2014

• DOI för High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile

Investigation of Hepatobiliary Disposition of Doxorubicin Following Intrahepatic Delivery of Different Dosage Forms

Lilienberg, Elsa; Ebeling-Barbier, Charlotte; Nyman, Rickard; Hedeland, Mikael et al.

Ingår i Molecular Pharmaceutics, s. 131-144, 2014

• DOI för Investigation of Hepatobiliary Disposition of Doxorubicin Following Intrahepatic Delivery of Different Dosage Forms

The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs)

Rydevik, Axel; Thevis, Mario; Krug, Oliver; Bondesson, Ulf et al.

Ingår i Xenobiotica, s. 409-420, 2013

• DOI för The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs)

Development and in-house validation of a method for quantification of BMAA in mussels using dansyl chloride derivatization and ultra performance liquid chromatography tandem mass spectrometry

Salomonsson, Matilda Lampinen; Hansson, Annelie; Bondesson, Ulf

Ingår i Analytical Methods, s. 4865-4874, 2013

• DOI för Development and in-house validation of a method for quantification of BMAA in mussels using dansyl chloride derivatization and ultra performance liquid chromatography tandem mass spectrometry

Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

Ingår i Journal of Pharmaceutical and Biomedical Analysis, s. 278-284, 2013

• DOI för Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO

High inter-individual variability of vardenafil pharmacokinetics in patients with pulmonary hypertension

Sandqvist, A. M.; Henrohn, Dan; Schneede, J.; Hedeland, Mikael et al.

Ingår i European Journal of Clinical Pharmacology, s. 197-207, 2013

• DOI för High inter-individual variability of vardenafil pharmacokinetics in patients with pulmonary hypertension

Methadone in healthy goats: Pharmacokinetics, behaviour and blood pressure

Olsen, L.; Olsson, K.; Hydbring-Sandberg, E.; Bondesson, Ulf et al.

Ingår i Research in Veterinary Science, s. 231-237, 2013

• DOI för Methadone in healthy goats: Pharmacokinetics, behaviour and blood pressure

Intramuscular administration of sodium benzylpenicillin in horses as an alternative to procaine benzylpenicillin

Olsen, Lena; Bremer, Hanna; Olofsson, Karin; Brojer, Johan et al.

Ingår i Research in Veterinary Science, s. 212-218, 2013

• DOI för Intramuscular administration of sodium benzylpenicillin in horses as an alternative to procaine benzylpenicillin

Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing

Guddat, S.; Fusshoeller, G.; Beuck, S.; Thomas, A. et al.

Ingår i Analytical and Bioanalytical Chemistry, s. 8285-8294, 2013

• DOI för Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing

Development and in-house validation of an LC-MS/MS method for the quantification of the mycotoxins deoxynivalenol, zearalenone, T-2 and HT-2 toxin, ochratoxin A and fumonisin B1 and B2 in vegetable animal feed

Tevell Åberg, Annica; Solyakov, Alexey; Bondesson, Ulf

Ingår i Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, s. 541-549, 2013

• DOI för Development and in-house validation of an LC-MS/MS method for the quantification of the mycotoxins deoxynivalenol, zearalenone, T-2 and HT-2 toxin, ochratoxin A and fumonisin B1 and B2 in vegetable animal feed

Acute haemodynamic response in relation to plasma vardenafil concentrations in patients with pulmonary hypertension

Henrohn, Dan; Sandqvist, Anna; Hedeland, Mikael; Egeröd, Hanna et al.

Ingår i British Journal of Clinical Pharmacology, s. 990-998, 2012

• DOI för Acute haemodynamic response in relation to plasma vardenafil concentrations in patients with pulmonary hypertension

Structural elucidation of phase I and II metabolites of bupivacaine in horse urine and fungi of the Cunninghamella species using liquid chromatography/multi-stage mass spectrometry

Rydevik, Axel; Bondesson, Ulf; Mikael, Hedeland

Ingår i Rapid Communications in Mass Spectrometry, s. 1338-1346, 2012

• DOI för Structural elucidation of phase I and II metabolites of bupivacaine in horse urine and fungi of the Cunninghamella species using liquid chromatography/multi-stage mass spectrometry

Characterization of In Vitro Synthesized Equine Metabolites of the Selective Androgen Receptor Modulators S24 and S4

Krug, Oliver; Thomas, Andreas; Beuck, Simon; Schenk, Ina et al.

Ingår i Journal of Equine Veterinary Science, s. 562-568, 2012

• DOI för Characterization of In Vitro Synthesized Equine Metabolites of the Selective Androgen Receptor Modulators S24 and S4

Detection of recombinant human EPO administered to horses using MAIIA lateral flow isoform test

Lönnberg, Maria; Bondesson, Ulf; Cormant, Florence; Garcia, Patrice et al.

Ingår i Analytical and Bioanalytical Chemistry, s. 1619-1628, 2012

• DOI för Detection of recombinant human EPO administered to horses using MAIIA lateral flow isoform test

Pharmacokinetics and effects of cetirizine in horses with insect bite hypersensitivity

Olsén, Lena; Bondesson, Ulf; Broström, Hans; Olsson, Ulf et al.

Ingår i The Veterinary Journal, s. 347-351, 2011

• DOI för Pharmacokinetics and effects of cetirizine in horses with insect bite hypersensitivity

Confirmation of botulism in birds and cattle by the mouse bioassay and Endopep-MS

Hedeland, Mikael; Moura, Hercules; Båverud, Viveca; Woolfitt, Adrian R et al.

Ingår i Journal of Medical Microbiology, s. 1299-1305, 2011

• DOI för Confirmation of botulism in birds and cattle by the mouse bioassay and Endopep-MS

Pharmacokinetics of meloxicam in adult goats and its analgesic effect in disbudded kids

Ingvast-Larsson, C.; Högberg, M.; Mengistu, U.; Olsén, L. et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 64-69, 2011

• DOI för Pharmacokinetics of meloxicam in adult goats and its analgesic effect in disbudded kids

In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5 alpha-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole

Lundahl, Anna; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Ingår i Drug Metabolism And Disposition, s. 847-857, 2011

• DOI för In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5 alpha-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole

Clinical pharmacology of methadone in dogs

Ingvast-Larsson, Carina; Holgersson, Anja; Bondesson, Ulf; Lagerstedt, Anne-Sofie et al.

Ingår i Veterinary Anaesthesia and Analgesia, s. 48-56, 2010

• DOI för Clinical pharmacology of methadone in dogs

Structural elucidation of N-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use of Cunninghamella elegans to facilitate drug metabolite identification

Tevell Åberg, Annica; Löfgren, Helena; Bondesson, Ulf; Hedeland, Mikael

Ingår i Rapid Communications in Mass Spectrometry, s. 1447-1456, 2010

• DOI för Structural elucidation of N-oxidized clemastine metabolites by liquid chromatography/tandem mass spectrometry and the use of Cunninghamella elegans to facilitate drug metabolite identification

Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers

Bergman, Ebba; Matsson, Elin M; Hedeland, Mikael; Bondesson, Ulf et al.

Ingår i Journal of clinical pharmacology, s. 1039-1049, 2010

• DOI för Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers

The Effect of Acute Administration of Rifampicin and Imatinib on the Enterohepatic Transport of Rosuvastatin In Vivo

Bergman, Ebba; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, Hans

Ingår i Xenobiotica, s. 558-568, 2010

• DOI för The Effect of Acute Administration of Rifampicin and Imatinib on the Enterohepatic Transport of Rosuvastatin In Vivo

A mass spectromeric study on meloxicam metabolism in horses and the fungus Cunninghamella elegans, and the relevance of this microbial system as a model of drug metabolism in the horse

Tevell Åberg, Annica; Olsson, Charlotte; Bondesson, Ulf; Hedeland, Mikael

Ingår i Journal of Mass Spectrometry, s. 1026-1037, 2009

• DOI för A mass spectromeric study on meloxicam metabolism in horses and the fungus Cunninghamella elegans, and the relevance of this microbial system as a model of drug metabolism in the horse

In vitro formation of phase I and II metabolites of propranolol and determination of their structures using chemical derivatization and liquid chromatography tandem mass spectrometry

Lampinen Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

Ingår i Journal of Mass Spectrometry, s. 742-754, 2009

• DOI för In vitro formation of phase I and II metabolites of propranolol and determination of their structures using chemical derivatization and liquid chromatography tandem mass spectrometry

The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

Lundahl, Anna; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 433-443, 2009

• DOI för The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

The Enterohepatic Disposition of Rosuvastatin in Pigs and The Impact of Concomitant Dosing with Cyclosporine and Gemfibrozil

Bergman, Ebba; Lundahl, Anna; Fridblom, Patrik; Hedeland, Mikael et al.

Ingår i Drug Metabolism And Disposition, s. 2349-2358, 2009

• DOI för The Enterohepatic Disposition of Rosuvastatin in Pigs and The Impact of Concomitant Dosing with Cyclosporine and Gemfibrozil

Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions

Thörn, Helena Anna; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars et al.

Ingår i Drug Metabolism And Disposition, s. 2186-2196, 2009

• DOI för Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions

Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry

Lundahl, Anna; Lennernäs, Hans; Knutson, Lars; Bondesson, Ulf et al.

Ingår i Drug Metabolism And Disposition, s. 2008-2017, 2009

• DOI för Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry

Cetirizine in horses: Pharmacokinetics and pharmacodynamics following repeated oral administration

Olsén, Lena; Bondesson, Ulf; Broström, Hans; Tjälve, Hans et al.

Ingår i The Veterinary Journal, s. 242-249, 2008

• DOI för Cetirizine in horses: Pharmacokinetics and pharmacodynamics following repeated oral administration

Structural evaluation of the glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and liquid chromatography/ion trap mass spectrometry

Lampinen Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

Ingår i Rapid Communications in Mass Spectrometry, s. 2685-2697, 2008

• DOI för Structural evaluation of the glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and liquid chromatography/ion trap mass spectrometry

Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment

Olsén, L.; Ingvast-Larsson, C.; Bondesson, Ulf; Broström, H. et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 194-200, 2007

• DOI för Cetirizine in horses: pharmacokinetics and effect of ivermectin pretreatment

Clinical pharmacology of buprenorphine in healthy, lactating goats

Ingvast-Larsson, C.; Svartberg, K.; Hydbring-Sandberg, E.; Bondesson, Ulf et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 249-256, 2007

• DOI för Clinical pharmacology of buprenorphine in healthy, lactating goats

Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase.

Bergman, Ebba; Forsell, Patrik; Tevell, Annica; Persson, Eva M et al.

Ingår i Eur J Pharm Sci, s. 205-14, 2006

First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

Petri, Niclas; Bergman, Ebba; Forsell, Patrik; Hedeland, Mikael et al.

Ingår i Drug Metab Dispos, s. 1182-9, 2006

Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

Petri, N; Borga, O; Nyberg, L; Hedeland, M et al.

Ingår i Int J Clin Pharmacol Ther, s. 71-9, 2006

Detection of altrenogest and its metabolites in post administration horse urine using liquid chromatography tandem mass spectrometry-increased sensitivity by chemical derivatisation of the glucuronic acid conjugate.

Lampinen-Salomonsson, Matilda; Beckman, Elin; Bondesson, Ulf; Hedeland, Mikael

Ingår i J Chromatogr B Analyt Technol Biomed Life Sci, s. 245-56, 2006

Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.

Olsén, L; Ingvast-Larsson, C; Larsson, P; Broström, H et al.

Ingår i J Vet Pharmacol Ther, s. 129-35, 2006

Differentiation of estriol glucuronide isomers by chemical derivatization and electrospray tandem mass spectrometry

Lampinen-Salomonsson, Matilda; Bondesson, Ulf; Petersson, Carl; Hedeland, Mikael

Ingår i Rapid Commun Mass Spectrom, s. 1429-40, 2006

Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Lennernäs, Hans; Jönsson, Mats; Norlin, Maria et al.

Ingår i Drug Metab Dispos, s. 984-92, 2006

St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism

Tannergren, Christer; Engman, Helena; Knutson, Lars; Hedeland, Mikael et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 298-309, 2004

• DOI för St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism

Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry

Hedeland, Mikael; Fredriksson, Elisabeth; Lennernäs, Hans; Bondesson, Ulf

Ingår i Journal of chromatography. B, s. 303-311, 2004

• DOI för Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry

Identification of some new clemastine metabolites in dog, horse, and human urine with liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Bondesson, Ulf; Törneke, Karolina; Hedeland, Mikael

Ingår i Rapid Commun Mass Spectrom, s. 2267-72, 2004

Clinical pharmacology of clemastine in healthy dogs.

Hansson, H; Bergvall, K; Bondesson, U; Hedeland, M et al.

Ingår i Vet Dermatol, s. 152-8, 2004

Development of a chiral non-aqueous capillary electrophoretic system using the partial filling technique with UV and mass spectrometric detection

Lodén, Henrik; Hedeland, Ylva; Hedeland, Mikael; Bondesson, Ulf et al.

Ingår i Journal of Chromatography A, s. 143-152, 2003

• DOI för Development of a chiral non-aqueous capillary electrophoretic system using the partial filling technique with UV and mass spectrometric detection

Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte

Hedeland, Ylva; Hedeland, Mikael; Bondesson, Ulf; Pettersson, Curt

Ingår i Journal of Chromatography A, s. 261-271, 2003

• DOI för Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte

Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

Tannergren, Christer; Petri, Niclas; Knutson, Lars; Hedeland, Mikael et al.

Ingår i Clin Pharmacol Ther, s. 423-36, 2003

Non-aquoeus capillary electrophoretic separation of enantiomeric amines with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiral counter ion

Carlsson, Ylva; Hedeland, Mikael; Bondesson, Ulf; Pettersson, Curt

Ingår i Journal of Chromatography A, s. 303-311, 2001

• DOI för Non-aquoeus capillary electrophoretic separation of enantiomeric amines with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiral counter ion

Non-aqueous capillary electrophoretic separation of enantiomeric amineswith (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid as chiralcounter ion.

Carlsson, Y; Hedeland, M; Bondesson, U; Pettersson, C

Ingår i J Chromatogr A, s. 303, 2001

Characterization of a Selective Androgen Receptor Modulator Drug Candidate and Identification of In Vitro Generated Metabolites for Sports Drug Testing

Hansson, Annelie; Thevis, Mario; Lagodja, Andreas; Thomas, Andreas et al.

2015

Antihistamine effect of cetirizine after oral administrator in the dog

Ekstrand, Carl; Ingvast-Larsson, Carina; Bondesson, Ulf; Hedeland, Mikael et al.

2015

A quantitative approach to analysing hydrocortisone response in the horse

Ekstrand, Carl; Ingvast-Larsson, Carina; Olsén, Lena; Hedeland, Mikael et al.

2015

Quantification of SARMs S1, S4 and S22 and detection of their metabolites in equine plasma usning UHPLC-Q-TOF

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

2015

Quantification of SARMs S1, S4 and S22 and detection of their metabolites in equine plasma using UHPLC-Q-TOF

Hansson, Annelie; Knych, Heather; Stanley, Scott; Thevis, Mario et al.

2015

Charactierization of a selective androgen receptor modulator drug candidate and identification of in vitro generated metabolites for sports drug testing

Thevis, Mario; Lagojda, Andreas; Thomas, Andreas; Dib, Josef et al.

2015

In vivo metabolism of selective androgen receptor modulators (SARMs) in the horse

Hedeland, Mikael; Hansson, Annelie; Rydevik, Axel; Krug, Oliver et al.

2014

In vivo metabolism of Selective Androgen Receptor Modulators (SARMs) in the horse

Hedeland, Mikael; Hansson, Annelie; Rydevik, Axel; Krug, Oliver et al.

2014

Validation of the endopep-MS method for qualitative detection of active botulinum neurotoxins in human or chicken serum

Björnstad, Kristian; Tevell Åberg, Annica; Kalb, Suzanne; Wang, Dongxia et al.

2014

Additional evidence for dexamethasone screening limits

Ekstrand, Carl; Bondesson, Ulf; Falkenö, Ulrika; Gabrielsson, Johan et al.

2014

Drug glucuronides synthesized using a new concept combining Cunninghamella elegans with TEMPO

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

2013

Turning drug glucosides into glucuronides - making fungal incubations work together with chemical derivatization

Rydevik, Axel; Bondesson, Ulf; Thevis, Mario; Hedeland, Mikael

2013

Evaluation of the fungus Cunninghamella elegans as a model for the formation of reactive metabolites using glutathione trapping and UHPLCC/HRMS

Rydevik, Axel; Hellqvist, Anna; Bondesson, Ulf; Hedeland, Mikael

2013

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

A mass spectrometric study of bupivacaine metabolites found in fungi and horse

Rydevik, Axel; Bondesson, Ulf; Hedeland, Mikael

2012

Improved Pharmacokinetic Understanding of Two Formulations for Intra-arterial Injection

Lilienberg, E; Ebeling Barbier, C; Nyman, R; Hedeland, Mikael et al.

2012

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

Comparison of vardenafil and adenosine for vasoreactivity testing in patients with pulmonary hypertension

Sandqvist, A; Henrohn, D; Schneede, J; Egerod, H et al.

2012

Verapamil Affects the Pharmacokinetics and the Hepatic Disposition of Fexofenadine in Pigs

Sjögren, E; Hedeland, Mikael; Bondesson, Ulf; Lennernäs, H

2012

A mass spectrometric study of bupivacaine metabolites found in fungi and horse

Rydevik, Axel; Hedeland, Mikael; Bondesson, Ulf

2012

Mass spectrometric study of the metabolism of Selective Androgen Receptor Modulators (SARMs) in the fungus Cunninghamella elegans

Hedeland, Mikael; Rydevik, Axel; Krug, O; Thevis, M et al.

2012

Improved Pharmacokinetic Understanding of Two Formulations for Intra-arterial Injection

Lilienberg, E; Ebeling Barbier, C; Nyman, R; Hedeland, Mikael et al.

2012

Local and sustained release in the treatment of primary liver cancer? Pharmacokinetic understanding of two formulations for intra arterial injection

Lilienberg, E; Ebeling Barbier, C; Nyman, C; Hedeland, Mikael et al.

2012

The relevance of using a fungus as a model of equine metabolism

Hedeland, Mikael; Tevell Åberg, Annica; Bondesson, Ulf

2010

Metabolite identification by mass spectrometry of the 5α-reductase inhibitor finasteride in vitro and in vivo

Lundahl, A; Tevell Åberg, Annica; Bondesson, Ulf; Hedeland, Mikael et al.

2009

Metabolitidentifiering av finasterid i human galla och urin

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2009

Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver

Thörn, H; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2009

The effect of gemfibrozil on the biliary excretion of rosuvastatin in pig and man

Bergman, E; Lundahl, A; Forsell, P; Hedeland, Mikael et al.

2009

Identification of hydroxylated and glucuronidated metabolites of finasteride in human bile and urine

Lundahl, A; Lennernäs, H; Knutson, L; Bondesson, Ulf et al.

2009

The hepatobiliary disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine.

Bergman, E; Lundahl, A; Forsell, P; Hedeland, Mikael et al.

2009

Characterization of C- and N-oxidized Clemastine Metabolites using LC-MSⁿ

Tevell Åberg, Annica; Bondesson, Ulf; Hedeland, Mikael

2008

Structural evaluation of glucuronides of morphine and formoterol using chemical derivatization with 1,2-dimethylimidazole-4-sulfonyl chloride and LC-MSⁿ

Salomonsson, Matilda; Bondesson, Ulf; Hedeland, Mikael

2008

Intestinal and liver CYP3A4-mediated metabolism of R/S-verapamil in pigs

Eriksson, H; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The effect of St John's Wort on the pharmacokinetics and metabolism of finasteride in healthy men

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutsson, L et al.

2008

The effect of St John’s wort on the pharmacokinetics and metabolism of finasteride in man

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The effect of St. John’s wort treatment on finasteride pharmacokinetics and identification of new phase I and phase II metabolites in humans

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The biliary excretion of rosuvastatin and gemfibrozil in healthy humans

Bergman, E; Sjödin, E; Forsell, P; Hedeland, Mikael et al.

2008

The effect of St John’s Wort treatment on finasteride metabolism and identification of new finasteride metabolites in humans

Lundahl, A; Hedeland, Mikael; Bondesson, Ulf; Knutson, L et al.

2008

The biliary excretion of rosuvastatin and gemfibrozil in healthy humans

Bergman, E; Sjödin, E; Forsell, P; Hedeland, Mikael et al.

2008

Optimization of In Vitro Microsome Incubations for Improved Drug Metabolite Yield Utilizing Experimental Design

Nilsson Broberg, Malin; Haglöf, Jakob; Bondesson, Ulf; Pettersson, Curt et al.