Jonatan Halvardson

Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hussain, Sultana Monira; Bjurling, Josefin; Yu, Chenglong; Tonkin, Andrew M. et al.

Ingår i Journal of the American College of Cardiology, s. 36-45, 2026

• DOI för Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Arai, Yohei; Chavkin, Nicholas W.; Arai, Yuka; Halvardson, Jonatan et al.

Ingår i Science Translational Medicine, 2025

• DOI för Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Bjurling, Josefin; Chavkin, Nicholas W.; Halvardson, Jonatan; Thel, Mark C. et al.

Ingår i Communications Medicine, 2025

• DOI för Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis
• Ladda ner fulltext (pdf) av Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Loss of chromosome Y in regulatory T cells

Mattisson, Jonas; Halvardson, Jonatan; Davies, Hanna; Bruhn-Olszewska, Bozena et al.

Ingår i BMC Genomics, 2024

• DOI för Loss of chromosome Y in regulatory T cells
• Ladda ner fulltext (pdf) av Loss of chromosome Y in regulatory T cells

Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Ingår i Leukemia, s. 889-891, 2022

• DOI för Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
• Ladda ner fulltext (pdf) av Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hussain, Sultana Monira; Bjurling, Josefin; Yu, Chenglong; Tonkin, Andrew M. et al.

Ingår i Journal of the American College of Cardiology, s. 36-45, 2026

• DOI för Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Arai, Yohei; Chavkin, Nicholas W.; Arai, Yuka; Halvardson, Jonatan et al.

Ingår i Science Translational Medicine, 2025

• DOI för Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Bjurling, Josefin; Chavkin, Nicholas W.; Halvardson, Jonatan; Thel, Mark C. et al.

Ingår i Communications Medicine, 2025

• DOI för Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis
• Ladda ner fulltext (pdf) av Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Loss of chromosome Y in regulatory T cells

Mattisson, Jonas; Halvardson, Jonatan; Davies, Hanna; Bruhn-Olszewska, Bozena et al.

Ingår i BMC Genomics, 2024

• DOI för Loss of chromosome Y in regulatory T cells
• Ladda ner fulltext (pdf) av Loss of chromosome Y in regulatory T cells

Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Ingår i Leukemia, s. 889-891, 2022

• DOI för Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
• Ladda ner fulltext (pdf) av Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan et al.

Ingår i Science, s. 292-297, 2022

• DOI för Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

Dumanski, Jan P.; Halvardson, Jonatan; Davies, Hanna; Rychlicka-Buniowska, Edyta et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 4019-4033, 2021

• DOI för Immune cells lacking Y chromosome show dysregulation of autosomal gene expression
• Ladda ner fulltext (pdf) av Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

Reply to Veitia

Danielsson, Marcus; Halvardson, Jonatan; Mattisson, Jonas; Forsberg, Lars A.

Ingår i European Journal of Human Genetics, s. 1323-1324, 2021

• DOI för Reply to Veitia
• Ladda ner fulltext (pdf) av Reply to Veitia

Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Mattisson, Jonas; Danielsson, Marcus; Hammond, Maria; Davies, Hanna et al.

Ingår i Scientific Reports, 2021

• DOI för Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99
• Ladda ner fulltext (pdf) av Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

Riaz, Moeen; Mattisson, Jonas; Polekhina, Galina; Bakshi, Andrew et al.

Ingår i Cell & Bioscience, 2021

• DOI för A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
• Ladda ner fulltext (pdf) av A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Lindholm Carlström, Eva; Niazi, Adnan; Etemadikhah, Mitra; Halvardson, Jonatan et al.

Ingår i Genes, 2021

• DOI för Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients
• Ladda ner fulltext (pdf) av Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder

Ramos, Jillian; Proven, Melissa; Halvardson, Jonatan; Hagelskamp, Felix et al.

Ingår i RNA, s. 1654-1666, 2020

• DOI för Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder
• Ladda ner fulltext (pdf) av Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder

Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

Danielsson, Marcus; Halvardson, Jonatan; Davies, Hanna; Moghadam, Behrooz Torabi et al.

Ingår i European Journal of Human Genetics, s. 349-357, 2020

• DOI för Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals
• Ladda ner fulltext (pdf) av Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family

Lindholm Carlström, Eva; Halvardson, Jonatan; Etemadikhah, Mitra; Wetterberg, Lennart et al.

Ingår i BMC Medical Genomics, 2019

• DOI för Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family
• Ladda ner fulltext (pdf) av Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family

Genetic predisposition to mosaic Y chromosome loss in blood

Thompson, Deborah J; Genovese, Giulio; Halvardson, Jonatan; Ulirsch, Jacob C et al.

Ingår i Nature, s. 652-657, 2019

• DOI för Genetic predisposition to mosaic Y chromosome loss in blood

Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development

Johansson, Martin M.; Pottmeier, Philipp; Suciu, Pascalina; Ahmed, Tauseef et al.

Ingår i Frontiers in Genetics, 2019

• DOI för Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development
• Ladda ner fulltext (pdf) av Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development

Mosaic loss of chromosome Y in leukocytes matters

Forsberg, Lars A.; Halvardson, Jonatan; Rychlicka-Buniowska, Edyta; Danielsson, Marcus et al.

Ingår i Nature Genetics, s. 4-7, 2019

• DOI för Mosaic loss of chromosome Y in leukocytes matters

Whole genome sequencing of consanguineous families reveals novel pathogenic variants in intellectual disability

Thuresson, Ann-Charlotte; Zander, Cecilia; Zhao, Jin James; Halvardson, Jonatan et al.

Ingår i Clinical Genetics, s. 436-439, 2019

• DOI för Whole genome sequencing of consanguineous families reveals novel pathogenic variants in intellectual disability
• Ladda ner fulltext (pdf) av Whole genome sequencing of consanguineous families reveals novel pathogenic variants in intellectual disability

Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability

Zhao, Jin James; Halvardson, Jonatan; Zander, Cecilia; Zaghlool, Ammar et al.

Ingår i American Journal of Medical Genetics Part B, s. 10-20, 2018

• DOI för Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability
• Ladda ner fulltext (pdf) av Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability

Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function

Zhao, Jin James; Halvardson, Jonatan; Knaus, Alexej; Georgii-Hemming, Patrik et al.

Ingår i Human Mutation, s. 1394-1401, 2017

• DOI för Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function
• Ladda ner fulltext (pdf) av Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function

Mutations in HECW2 are associated with intellectual disability and epilepsy

Halvardson, Jonatan; Zhao, Jin J.; Zaghlool, Ammar; Wentzel, Christian et al.

Ingår i Journal of Medical Genetics, s. 697-704, 2016

• DOI för Mutations in HECW2 are associated with intellectual disability and epilepsy
• Ladda ner fulltext (pdf) av Mutations in HECW2 are associated with intellectual disability and epilepsy

Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development

Johansson, Martin; Lundin, Elin; Qian, Xiaoyan; Mirzazadeh, Mohammadreza et al.

Ingår i Biology of Sex Differences, 2016

• DOI för Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development
• Ladda ner fulltext (pdf) av Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development

A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment

Zaghlool, Ammar; Halvardson, Jonatan; Zhao, Jin J.; Etemadikhah, Mitra et al.

Ingår i Human Mutation, s. 964-975, 2016

• DOI för A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment
• Ladda ner fulltext (pdf) av A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment

Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling

Schuster, Jens; Halvardson, Jonatan; Lorenzo, Laureanne Pilar; Ameur, Adam et al.

Ingår i Cellular Reprogramming, s. 327-337, 2015

• DOI för Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling

Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy

Spiegel, Ronen; Saada, Ann; Halvardson, Jonatan; Soiferman, Devorah et al.

Ingår i European Journal of Human Genetics, s. 902-906, 2014

• DOI för Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy

Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues

Zaghlool, Ammar; Ameur, Adam; Nyberg, Linnea; Halvardson, Jonatan et al.

Ingår i BMC Biotechnology, s. 99, 2013

• DOI för Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues
• Ladda ner fulltext (pdf) av Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues

Exome RNA sequencing reveals rare and novel alternative transcripts

Halvardson, Jonatan; Zaghlool, Ammar; Feuk, Lars

Ingår i Nucleic Acids Research, 2013

• DOI för Exome RNA sequencing reveals rare and novel alternative transcripts

RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes

Radomska, Katarzyna J.; Halvardson, Jonatan; Reinius, Björn; Carlström, Eva Lindholm et al.

Ingår i Human Molecular Genetics, s. 1373-1382, 2013

• DOI för RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes

Intractable epilepsy of infancy due to homozygous mutation in the EFHC1 gene

Berger, Itai; Dor, Talya; Halvardson, Jonatan; Edvardson, Simon et al.

Ingår i Epilepsia, s. 1436-1440, 2012

• DOI för Intractable epilepsy of infancy due to homozygous mutation in the EFHC1 gene

Infantile Cerebellar-Retinal Degeneration Associated with a Mutation in Mitochondrial Aconitase, ACO2

Spiegel, Konen; Pines, Ophry; Ta-Shma, Asaf; Burak, Efrat et al.

Ingår i American Journal of Human Genetics, s. 518-523, 2012

• DOI för Infantile Cerebellar-Retinal Degeneration Associated with a Mutation in Mitochondrial Aconitase, ACO2

Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain

Ameur, Adam; Zaghlool, Ammar; Halvardson, Jonatan; Wetterbom, Anna et al.

Ingår i Nature Structural & Molecular Biology, s. 1435-1440, 2011

• DOI för Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain

Sequence based analysis of neurodevelopmental disorders

Halvardson, Jonatan

2016

• Ladda ner fulltext (pdf) av Sequence based analysis of neurodevelopmental disorders

Mutation in the chromatin-remodeling factor BAZ1A is associated with intellectual disability

Zaghlool, Ammar; Halvardson, Jonatan; Zhao, Jin; Kalushkova, Antonia et al.