Gabriela Rosen

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Rahmanto, Aldwin Suryo; Savov, Vasil; Brunner, Andrä; Bolin, Sara et al.

Ingår i EMBO Journal, s. 2192-2212, 2016

• DOI för FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
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Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Ingår i Molecular Oncology, s. 333-346, 2012

• DOI för Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
• Ladda ner fulltext (pdf) av Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Ingår i BMC Immunology, s. 3, 2011

• DOI för Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
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Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Ingår i Cancer Research, s. 2141-2148, 2009

• DOI för Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies

Gudenas, Brian L.; Ahmad, Shiekh Tanveer; Englinger, Bernhard; Liu, Anthony P. Y. et al.

Ingår i Cancer Cell, s. 831-845, 2026

• DOI för A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies
• Ladda ner fulltext (pdf) av A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Ingår i Cell Death and Differentiation, s. 1915-1929, 2025

• DOI för The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
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ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Mainwaring, Oliver; Weishaupt, Holger; Zhao, Miao; Rosén, Gabriela et al.

Ingår i Nature Communications, 2023

• DOI för ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
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Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Weishaupt, Holger; Čančer, Matko; Rosén, Gabriela; Holmberg, Karl O. et al.

Ingår i Neuro-Oncology, s. 97-107, 2023

• DOI för Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas
• Ladda ner fulltext (pdf) av Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies

Gudenas, Brian L.; Ahmad, Shiekh Tanveer; Englinger, Bernhard; Liu, Anthony P. Y. et al.

Ingår i Cancer Cell, s. 831-845, 2026

• DOI för A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies
• Ladda ner fulltext (pdf) av A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Ingår i Cell Death and Differentiation, s. 1915-1929, 2025

• DOI för The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
• Ladda ner fulltext (pdf) av The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Mainwaring, Oliver; Weishaupt, Holger; Zhao, Miao; Rosén, Gabriela et al.

Ingår i Nature Communications, 2023

• DOI för ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
• Ladda ner fulltext (pdf) av ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Weishaupt, Holger; Čančer, Matko; Rosén, Gabriela; Holmberg, Karl O. et al.

Ingår i Neuro-Oncology, s. 97-107, 2023

• DOI för Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas
• Ladda ner fulltext (pdf) av Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Zhang, Hua; Polavarapu, Vamsi Krishna; Xing, Pengwei; Zhao, Miao et al.

Ingår i Genome Research, s. 150-161, 2022

• DOI för Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
• Ladda ner fulltext (pdf) av Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Ingår i Cell Death and Disease, 2019

• DOI för BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
• Ladda ner fulltext (pdf) av BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Ingår i Cell Stem Cell, s. 855-870, 2019

• DOI för Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
• Ladda ner fulltext (pdf) av Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

Weishaupt, Holger; Mainwaring, Oliver; Hutter, Sonja; Kalushkova, Antonia et al.

Ingår i Neuro-Oncology, s. 137-137, 2018

• DOI för GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Rahmanto, Aldwin Suryo; Savov, Vasil; Brunner, Andrä; Bolin, Sara et al.

Ingår i EMBO Journal, s. 2192-2212, 2016

• DOI för FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
• Ladda ner fulltext (pdf) av FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Ingår i Molecular Oncology, s. 333-346, 2012

• DOI för Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
• Ladda ner fulltext (pdf) av Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Ingår i BMC Immunology, s. 3, 2011

• DOI för Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
• Ladda ner fulltext (pdf) av Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Calounova, Gabriela; Livera, Gabriel; Zhang, X-Q; Liu, Kui et al.

Ingår i PLOS ONE, 2010

• DOI för The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Ingår i Cancer Research, s. 2141-2148, 2009

• DOI för Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Impaired glucose homeostasis in Shb-/- mice

Åkerblom, Björn; Barg, Sebastian; Calounova, Gabriela; Mokhtari, Dariush et al.

Ingår i Journal of Endocrinology, s. 271-279, 2009

• DOI för Impaired glucose homeostasis in Shb-/- mice

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Kriz, Vitezslav; Mares, Jaroslav; Wentzel, Parri; Funa, Nina S. et al.

Ingår i Developmental Dynamics, s. 2485-2492, 2007

• DOI för Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

CDK2 as a therapeutic target in MYC-driven medulloblastoma

Borgenvik, Anna; Rosén, Gabriela; Holmberg Olausson, Karl; Larsson, Lars-Gunnar et al.

Photoreceptor-positive cells of tumor origin in MYC-driven Group 3 medulloblastoma

Zhao, Miao; Mainwaring, Oliver; Rosén, Gabriela; Rijpkema, Sanne et al.

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.