Taj Muhammad
Forskare vid Institutionen för farmaceutisk biovetenskap; Forskning; Farmakognosi
- E-post:
- taj.muhammad@uu.se
- Besöksadress:
- BMC, Husargatan 3
75124 Uppsala - Postadress:
- Box 591
75124 Uppsala
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Forskning
Denna text finns inte på svenska, därför visas den engelska versionen.
My PhD work focus on the design and development of peptide antibiotics (based on human host defence peptide, LL-37) and different ways of creating them. In particular, I am interested to make these molecules protease resistant and to characterise structure as well as mode of killing.
Publikationer
Urval av publikationer
Senaste publikationer
- Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity (2024)
- Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation (2024)
- KR-12 derivatives endow nanocellulose with antibacterial and anti-inflammatory properties (2023)
- Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies (2023)
- A Synthetic Cyclized Antimicrobial Peptide with Potent Effects against Drug-Resistant Skin Pathogens (2023)
Alla publikationer
Artiklar
- Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity (2024)
- Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation (2024)
- KR-12 derivatives endow nanocellulose with antibacterial and anti-inflammatory properties (2023)
- Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies (2023)
- A Synthetic Cyclized Antimicrobial Peptide with Potent Effects against Drug-Resistant Skin Pathogens (2023)
- Exploring the limits of cyanobactin macrocyclase PatGmac (2023)
- Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads (2023)
- Screening for Cyclotides in Sri Lankan Medicinal Plants (2023)
- A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens (2022)
- Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides (2021)
- Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability (2020)
- Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens (2020)
- Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity (2018)
- Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins (2017)
- Single-step purification of cyclotides using affinity chromatography (2017)
- Fungi as a source for antibacterial compounds (2016)
- A bioactivity-guided screening of Sri Lankan plants in the search for novel antibacterial and anticancer agents (2016)
- Engineering Of A Minimalized Domain Derived From Human Host Defense Peptide LL-37 Into A Stable And Potent Antimicrobial Drug Lead (2016)
- Engineering of KR-12 (2016)
- Backbone-Cyclized Peptide Dimers Derived from Human Cathelicidin Peptide LL-37 Mediate Potent Antimicrobial Activity (2014)
- Ga-68-Labeling of RGD peptides and biodistribution (2012)
- Exploring the biological safety and the potential application of nemertide alpha-1 as a biopesticide on green peach aphids Myzus persicae.
- Immobilisation of semi-pure butelase 1 and its applications to produce head-to-tail cyclic peptides
- Transformation of KR-12 derived cross-linked cyclic dimers into stable and potent antimicrobial drug leads
Böcker
Konferenser
