Pawel Baranczewski

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

Hansson, Mats G.; Björkgren, Ida; Svedenkrans, Jenny; Backman, Helena et al.

Ingår i British Journal of Clinical Pharmacology, 2025

• DOI för Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

Melander, Erik; Nielsen, Elisabet I.; Lindqvist, Annika; Hovd, Markus et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, 2025

• DOI för Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project
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AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Ingår i Science Advances, 2024

• DOI för AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project

Nordeng, Hedvig; Wegler, Christine; Lindqvist, Annika; Melander, Erik et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 153-164, 2024

• DOI för Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
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Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

Hansson, Mats G.; Björkgren, Ida; Svedenkrans, Jenny; Backman, Helena et al.

Ingår i British Journal of Clinical Pharmacology, 2025

• DOI för Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

Melander, Erik; Nielsen, Elisabet I.; Lindqvist, Annika; Hovd, Markus et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, 2025

• DOI för Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project
• Ladda ner fulltext (pdf) av Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Ingår i Science Advances, 2024

• DOI för AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
• Ladda ner fulltext (pdf) av AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
• Ladda ner fulltext (pdf) av Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project

Nordeng, Hedvig; Wegler, Christine; Lindqvist, Annika; Melander, Erik et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 153-164, 2024

• DOI för Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
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Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Wegler, Christine; Saleh, Aljona; Lindqvist, Annika; Nordeng, Hedvig et al.

Ingår i Journal of chromatography. B, 2022

• DOI för Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Brem, Jürgen; Panduwawala, Tharindi; Hansen, Jon Ulf; Hewitt, Joanne et al.

Ingår i Nature Chemistry, s. 15-24, 2022

• DOI för Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

ENABLE: an engine for European antibacterial drug discovery and development

Olliver, Marie; Griestop, Laura; Hughes, Diarmaid; Belfrage, Anna Karin et al.

Ingår i Nature reviews. Drug discovery, s. 407-408, 2021

• DOI för ENABLE: an engine for European antibacterial drug discovery and development

A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

Matsson, Pär; Baranczewski, Pawel; Giacomini, Kathleen M.; Andersson, Tommy B. et al.

Ingår i Journal of Pharmaceutical Sciences, s. 2-11, 2021

• DOI för A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

Filppula, Anne M.; Parvizi, Rezvan; Mateus, André; Baranczewski, Pawel et al.

Ingår i Scientific Reports, 2019

• DOI för Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Page, Brent D. G.; Valerie, Nicholas C. K.; Wright, Roni H. G.; Wallner, Olov et al.

Ingår i Nature Communications, 2018

• DOI för Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
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Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound

Islam, Md. Koushikul; Strand, Mårten; Saleeb, Michael; Svensson, Richard et al.

Ingår i Scientific Reports, 2018

• DOI för Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Visnes, Torkild; Cazares-Korner, Armando; Hao, Wenjing; Wallner, Olov et al.

Ingår i Science, s. 834-839, 2018

• DOI för Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

Llona-Minguez, Sabin; Ghassemian, Artin; Baranczewski, Pawel; Desroses, Matthieu et al.

Ingår i MedChemComm, s. 1553-1560, 2017

• DOI för Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Llona-Minguez, Sabin; Höglund, Andreas; Wiita, Elisee; Almlof, Ingrid et al.

Ingår i Journal of Medicinal Chemistry, s. 2148-2154, 2017

• DOI för Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Llona-Minguez, Sabin; Höglund, Andreas; Ghassemian, Artin; Desroses, Matthieu et al.

Ingår i Journal of Medicinal Chemistry, s. 4279-4292, 2017

• DOI för Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Validation and development of MTH1 inhibitors for treatment of cancer

Berglund, U. Warpman; Sanjiv, K.; Gad, H.; Kalderen, C. et al.

Ingår i Annals of Oncology, s. 2275-2283, 2016

• DOI för Validation and development of MTH1 inhibitors for treatment of cancer
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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

Llona-Minguez, Sabin; Höglund, Andreas; Jacques, Sylvain A.; Johanson, Lars et al.

Ingår i Journal of Medicinal Chemistry, s. 1140-1148, 2016

• DOI för Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge; Koolmeister, Tobias; Jemth, Ann-Sofie; Eshtad, Saeed et al.

Ingår i Nature, s. 215-221, 2014

• DOI för MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data

Nordmark, Anna; Andersson, Anita; Baranczewski, Pawel; Wanag, Ewa et al.

Ingår i European Journal of Clinical Pharmacology, s. 167-178, 2014

• DOI för Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data