Xiaomei Chen

Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

Hamdan, Alzahra; Traschütz, Andreas; Beichert, Lukas; Chen, Xiaomei et al.

Ingår i CPT, s. 1857-1868, 2025

• DOI för Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases
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A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Ryeznik, Yevgen; Hilgers, Ralf-Dieter; Heussen, Nicole; Comets, Emmanuelle et al.

Ingår i CPT, s. 1705-1714, 2025

• DOI för A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders
• Ladda ner fulltext (pdf) av A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Bjugård Nyberg, Henrik; Chen, Xiaomei; Donnelly, Mark; Fang, Lanyan et al.

Ingår i CPT, s. 1748-1761, 2024

• DOI för Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods
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A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Ingår i CPT, s. 1784-1797, 2024

• DOI för A fully automatic tool for development of population pharmacokinetic models
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Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Hamdan, Alzahra; Hendrickx, Niels; Hooker, Andrew C.; Chen, Xiaomei et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 1593-1605, 2024

• DOI för Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory
• Ladda ner fulltext (pdf) av Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

Hamdan, Alzahra; Traschütz, Andreas; Beichert, Lukas; Chen, Xiaomei et al.

Ingår i CPT, s. 1857-1868, 2025

• DOI för Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases
• Ladda ner fulltext (pdf) av Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases

A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Ryeznik, Yevgen; Hilgers, Ralf-Dieter; Heussen, Nicole; Comets, Emmanuelle et al.

Ingår i CPT, s. 1705-1714, 2025

• DOI för A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders
• Ladda ner fulltext (pdf) av A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Bjugård Nyberg, Henrik; Chen, Xiaomei; Donnelly, Mark; Fang, Lanyan et al.

Ingår i CPT, s. 1748-1761, 2024

• DOI för Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods
• Ladda ner fulltext (pdf) av Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Ingår i CPT, s. 1784-1797, 2024

• DOI för A fully automatic tool for development of population pharmacokinetic models
• Ladda ner fulltext (pdf) av A fully automatic tool for development of population pharmacokinetic models

Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Hamdan, Alzahra; Hendrickx, Niels; Hooker, Andrew C.; Chen, Xiaomei et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 1593-1605, 2024

• DOI för Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory
• Ladda ner fulltext (pdf) av Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

Chen, Xiaomei; Bjugård Nyberg, Henrik; Donnelly, Mark; Zhao, Liang et al.

Ingår i CPT, s. 1734-1747, 2024

• DOI för Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points
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Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias

Hamdan, Alzahra; Hooker, Andrew C.; Chen, Xiaomei; Traschütz, Andreas et al.

Ingår i CPT, s. 1327-1340, 2024

• DOI för Item performance of the scale for the assessment and rating of ataxia in rare and ultra-rare genetic ataxias
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Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

Sharan, Satish; Fang, Lanyan; Lukacova, Viera; Chen, Xiaomei et al.

Ingår i Clinical Pharmacology in Drug Development, s. 220-228, 2021

• DOI för Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

Revisiting atenolol as a low passive permeability marker

Chen, Xiaomei; Slättengren, Tim; de Lange, Elizabeth C. M.; Smith, David E. et al.

Ingår i Fluids and Barriers of the CNS, 2017

• DOI för Revisiting atenolol as a low passive permeability marker
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Effect of transporter inhibitioin on the distribution of cefadroxil in rat brain

Chen, Xiaomei; Loryan, Irena; Payan, Maryam; Keep, Richard F. et al.

Ingår i Fluids and Barriers of the CNS, 2014

• DOI för Effect of transporter inhibitioin on the distribution of cefadroxil in rat brain
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Effect of transporter inhibition on the distribution of cefadroxil in rat brain

Chen, Xiaomei; Loryan, Irena; Payan, Maryam; Keep, Richard et al.

Ingår i Fluids and Barriers of the CNS, 2014

• DOI för Effect of transporter inhibition on the distribution of cefadroxil in rat brain
• Ladda ner fulltext (pdf) av Effect of transporter inhibition on the distribution of cefadroxil in rat brain