Stefan Gustafsson

Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms

Gustafson Hedov, Emelie; Nyberg, Fredrik; Gustafsson, Stefan; Li, Huiqi et al.

Ingår i JMIR Formative Research, 2024

• DOI för Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms
• Ladda ner fulltext (pdf) av Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms

Markers of imminent myocardial infarction

Gustafsson, Stefan; Lampa, Erik; Jensevik Eriksson, Karin; Butterworth, Adam S. et al.

Ingår i Nature Cardiovascular Research, s. 130-139, 2024

• DOI för Markers of imminent myocardial infarction
• Ladda ner fulltext (pdf) av Markers of imminent myocardial infarction

Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals

Sundström, Johan; Gustafsson, Stefan; Cars, Thomas; Lindholm, Daniel P

Ingår i European Journal of Heart Failure, s. 2443-2450, 2024

• DOI för Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals
• Ladda ner fulltext (pdf) av Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals

Evaluating regression and probabilistic methods for ECG-based electrolyte prediction

von Bachmann, Philipp; Gedon, Daniel; Gustafsson, Fredrik K.; Ribeiro, Antônio H. et al.

Ingår i Scientific Reports, 2024

• DOI för Evaluating regression and probabilistic methods for ECG-based electrolyte prediction
• Ladda ner fulltext (pdf) av Evaluating regression and probabilistic methods for ECG-based electrolyte prediction

Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation

Lind, Lars; Titova, Olga; Zeng, Rui; Zanetti, Daniela et al.

Ingår i CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2023

• DOI för Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation
• Ladda ner fulltext (pdf) av Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation

Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms

Gustafson Hedov, Emelie; Nyberg, Fredrik; Gustafsson, Stefan; Li, Huiqi et al.

Ingår i JMIR Formative Research, 2024

• DOI för Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms
• Ladda ner fulltext (pdf) av Person-Centered Web-Based Mobile Health System (Symptoms) for Reporting Symptoms in COVID-19 Vaccinated Individuals: Observational Study of System, Users, and Symptoms

Markers of imminent myocardial infarction

Gustafsson, Stefan; Lampa, Erik; Jensevik Eriksson, Karin; Butterworth, Adam S. et al.

Ingår i Nature Cardiovascular Research, s. 130-139, 2024

• DOI för Markers of imminent myocardial infarction
• Ladda ner fulltext (pdf) av Markers of imminent myocardial infarction

Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals

Sundström, Johan; Gustafsson, Stefan; Cars, Thomas; Lindholm, Daniel P

Ingår i European Journal of Heart Failure, s. 2443-2450, 2024

• DOI för Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals
• Ladda ner fulltext (pdf) av Heart failure treatment in the last years of life: A nationwide study of 364 000 individuals

Evaluating regression and probabilistic methods for ECG-based electrolyte prediction

von Bachmann, Philipp; Gedon, Daniel; Gustafsson, Fredrik K.; Ribeiro, Antônio H. et al.

Ingår i Scientific Reports, 2024

• DOI för Evaluating regression and probabilistic methods for ECG-based electrolyte prediction
• Ladda ner fulltext (pdf) av Evaluating regression and probabilistic methods for ECG-based electrolyte prediction

Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation

Lind, Lars; Titova, Olga; Zeng, Rui; Zanetti, Daniela et al.

Ingår i CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2023

• DOI för Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation
• Ladda ner fulltext (pdf) av Plasma Protein Profiling of Incident Cardiovascular Diseases: A Multisample Evaluation

Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases A Mendelian Randomization Study

Donovan, Killian; Herrington, William G.; Pare, Guillaume; Pigeyre, Marie et al.

Ingår i American Society of Nephrology. Clinical Journal, s. 17-27, 2023

• DOI för Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases A Mendelian Randomization Study
• Ladda ner fulltext (pdf) av Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases A Mendelian Randomization Study

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

Carland, Corinne; Png, Grace; Malarstig, Anders; Kho, Pik Fang et al.

Ingår i Clinical Proteomics, 2023

• DOI för Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
• Ladda ner fulltext (pdf) av Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Williamson, Alice; Norris, Dougall M; Yin, Xianyong; Broadaway, K Alaine et al.

Ingår i Nature Genetics, s. 973-983, 2023

• DOI för Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts

Zanetti, Daniela; Stell, Laurel; Gustafsson, Stefan; Abbasi, Fahim et al.

Ingår i Diabetologia, s. 1643-1654, 2023

• DOI för Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts
• Ladda ner fulltext (pdf) av Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts

Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

Li, Jiehan; Jin, Christopher; Gustafsson, Stefan; Rao, Abhiram et al.

Ingår i Scientific Data, 2023

• DOI för Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
• Ladda ner fulltext (pdf) av Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

Broadaway, K Alaine; Yin, Xianyong; Williamson, Alice; Parsons, Victoria A et al.

Ingår i American Journal of Human Genetics, s. 284-299, 2023

• DOI för Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Ramdas, Shweta; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Ingår i American Journal of Human Genetics, s. 1366-1387, 2022

• DOI för A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

A saturated map of common genetic variants associated with human height

Yengo, Loic; Gustafsson, Stefan; Lind, Lars; Hirschhorn, Joel N.

Ingår i Nature, s. 704-712, 2022

• DOI för A saturated map of common genetic variants associated with human height
• Ladda ner fulltext (pdf) av A saturated map of common genetic variants associated with human height

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni, Stavroula; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Ingår i Genome Biology, 2022

• DOI för Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
• Ladda ner fulltext (pdf) av Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stroke genetics informs drug discovery and risk prediction across ancestries

Mishra, Aniket; den Hoed, Marcel; Gustafsson, Stefan; Ingelsson, Erik et al.

Ingår i Nature, s. 115-+, 2022

• DOI för Stroke genetics informs drug discovery and risk prediction across ancestries
• Ladda ner fulltext (pdf) av Stroke genetics informs drug discovery and risk prediction across ancestries

Development and validation of deep learning ECG-based prediction of myocardial infarction in emergency department patients

Gustafsson, Stefan; Gedon, Daniel; Lampa, Erik; Horta Ribeiro, Antônio et al.

Ingår i Scientific Reports, 2022

• DOI för Development and validation of deep learning ECG-based prediction of myocardial infarction in emergency department patients
• Ladda ner fulltext (pdf) av Development and validation of deep learning ECG-based prediction of myocardial infarction in emergency department patients

Genetic Landscape of the ACE2 Coronavirus Receptor

Yang, Zhijian; Macdonald-Dunlop, Erin; Chen, Jiantao; Zhai, Ranran et al.

Ingår i Circulation, s. 1398-1411, 2022

• DOI för Genetic Landscape of the ACE2 Coronavirus Receptor
• Ladda ner fulltext (pdf) av Genetic Landscape of the ACE2 Coronavirus Receptor

A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections

Tängdén, Thomas; Gustafsson, Stefan; Rao, Abhiram S.; Ingelsson, Erik

Ingår i Scientific Reports, 2022

• DOI för A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections
• Ladda ner fulltext (pdf) av A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections

Renin-Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID-19

Loader, Jordan; Lampa, Erik; Gustafsson, Stefan; Cars, Thomas et al.

Ingår i Journal of the American Heart Association, 2021

• DOI för Renin-Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID-19
• Ladda ner fulltext (pdf) av Renin-Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID-19

A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

Jhun, Mina-A; Mendelson, Michael; Wilson, Rory; Gondalia, Rahul et al.

Ingår i Nature Communications, 2021

• DOI för A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
• Ladda ner fulltext (pdf) av A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

The trans-ancestral genomic architecture of glycemic traits

Chen, Ji; Gustafsson, Stefan; Sennblad, Bengt; Lind, Lars et al.

Ingår i Nature Genetics, s. 840-860, 2021

• DOI för The trans-ancestral genomic architecture of glycemic traits

Large-Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure

Lind, Lars; Zanetti, Daniela; Ingelsson, Martin; Gustafsson, Stefan et al.

Ingår i Journal of the American Heart Association, 2021

• DOI för Large-Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure
• Ladda ner fulltext (pdf) av Large-Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure

The power of genetic diversity in genome-wide association studies of lipids

Graham, Sarah E.; Gustafsson, Stefan; Lind, Lars; Ingelsson, Erik et al.

Ingår i Nature, s. 675-679, 2021

• DOI för The power of genetic diversity in genome-wide association studies of lipids

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

Klaric, Lucija; Gisby, Jack S; Papadaki, Artemis; Muckian, Marisa D et al.

Ingår i medRxiv : the preprint server for health sciences, s. 1-28, 2021

• DOI för Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Folkersen, Lasse; Gustafsson, Stefan; Wang, Qin; Hvidberg Hansen, Daniel et al.

Ingår i Nature Metabolism, s. 1135-1148, 2020

• DOI för Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events

Zanetti, Daniela; Gustafsson, Stefan; Assimes, Themistocles L.; Ingelsson, Erik

Ingår i Circulation, s. 671-685, 2020

• DOI för Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events

Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion

Zanetti, Daniela; Rao, Abhiram; Gustafsson, Stefan; Assimes, Themistocles L. et al.

Ingår i Kidney International, s. 1197-1208, 2019

• DOI för Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Justice, Anne E.; Giedraitis, Vilmantas; Gustafsson, Stefan; Ingelsson, Erik et al.

Ingår i Nature Genetics, s. 452-469, 2019

• DOI för Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Schmidt, Amand F.; Holmes, Michael V.; Preiss, David; Swerdlow, Daniel I. et al.

Ingår i BMC Cardiovascular Disorders, 2019

• DOI för Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
• Ladda ner fulltext (pdf) av Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

Helle, Emmi; Cordova-Palomera, Aldo; Ojala, Tiina; Saha, Priyanka et al.

Ingår i Genetic Epidemiology, s. 215-226, 2019

• DOI för Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

Body composition and atrial fibrillation: a Mendelian randomization study

Tikkanen, Emmi; Gustafsson, Stefan; Knowles, Joshua W.; Perez, Marco et al.

Ingår i European Heart Journal, s. 1277-1282, 2019

• DOI för Body composition and atrial fibrillation: a Mendelian randomization study

Proteomic Analysis of Longitudinal Changes in Blood Pressure

Yi-Ting, Lin; Fall, Tove; Hammar, Ulf; Gustafsson, Stefan et al.

Ingår i Journal of Clinical Medicine, 2019

• DOI för Proteomic Analysis of Longitudinal Changes in Blood Pressure
• Ladda ner fulltext (pdf) av Proteomic Analysis of Longitudinal Changes in Blood Pressure

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

Dörr, Marcus; Hamburg, Naomi M.; Müller, Christian; Smith, Nicholas L. et al.

Ingår i Circulation, 2019

• DOI för Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation

Harati, Hadi; Zanetti, Daniela; Rao, Abhiram; Gustafsson, Stefan et al.

Ingår i Diabetologia, s. 800-804, 2019

• DOI för No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Pulit, Sara L.; Gustafsson, Stefan; Lind, Lars; Lannfelt, Lars et al.

Ingår i NEUROLOGY-GENETICS, 2018

• DOI för Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
• Ladda ner fulltext (pdf) av Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

Nielsen, Jonas B.; Fritsche, Lars G.; Zhou, Wei; Teslovich, Tanya M. et al.

Ingår i American Journal of Human Genetics, s. 103-115, 2018

• DOI för Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Figarska, Sylwia M.; Gustafsson, Stefan; Sundström, Johan; Ärnlöv, Johan et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2505-2518, 2018

• DOI för Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease Longitudinal Analyses in the UK Biobank Study

Tikkanen, Emmi; Gustafsson, Stefan; Ingelsson, Erik

Ingår i Circulation, s. 2583-2591, 2018

• DOI för Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease Longitudinal Analyses in the UK Biobank Study

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Chen, Xu; Gustafsson, Stefan; Whitington, Thomas; Borne, Yan et al.

Ingår i Human Molecular Genetics, s. 1809-1818, 2018

• DOI för A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Clinical and genetic determinants of varicose veins: a prospective, community-based prospective study of similar to 500,000 individuals

Fukaya, Eri; Flores, Alyssa; Lindholm, Daniel; Gustafsson, Stefan et al.

Ingår i Vascular Medicine, s. 300-300, 2018

Clinical and Genetic Determinants of Varicose Veins Prospective, Community-Based Study of approximate to 500 000 Individuals

Fukaya, Eri; Flores, Alyssa M.; Lindholm, Daniel P; Gustafsson, Stefan et al.

Ingår i Circulation, s. 2869-2880, 2018

• DOI för Clinical and Genetic Determinants of Varicose Veins Prospective, Community-Based Study of approximate to 500 000 Individuals

Use of Proteomics to Investigate Blood Pressure Progress in the Elderly

Yi-Ting, Lin; Fall, Tove; Gustafsson, Stefan; Ingelsson, Erik et al.

Ingår i Journal of Hypertension, 2018

• DOI för Use of Proteomics to Investigate Blood Pressure Progress in the Elderly

Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization

Zanetti, Daniela; Tikkanen, Emmi; Gustafsson, Stefan; Priest, James R. et al.

Ingår i Circulation, 2018

• DOI för Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization
• Ladda ner fulltext (pdf) av Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization

Multi-ethnic genome-wide association study for atrial fibrillation

Roselli, Carolina; Chaffin, Mark D.; Weng, Lu-Chen; Aeschbacher, Stefanie et al.

Ingår i Nature Genetics, s. 1225-1233, 2018

• DOI för Multi-ethnic genome-wide association study for atrial fibrillation

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank

Tikkanen, Emmi; Gustafsson, Stefan; Amar, David; Shcherbina, Anna et al.

Ingår i Scientific Reports, 2018

• DOI för Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank
• Ladda ner fulltext (pdf) av Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, Anubha; Wessel, Jennifer; Willems, Sara M.; Zhao, Wei et al.

Ingår i Nature Genetics, s. 559-571, 2018

• DOI för Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan et al.

Ingår i Nature Genetics, s. 524-537, 2018

• DOI för Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, Valerie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia et al.

Ingår i Nature Genetics, s. 26-+, 2018

• DOI för Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank

Fall, Tove; Gustafsson, Stefan; Orho-Melander, Marju; Ingelsson, Erik

Ingår i Diabetologia, s. 2174-2179, 2018

• DOI för Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank
• Ladda ner fulltext (pdf) av Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank

A DNA methylation biomarker of alcohol consumption.

Liu, C; Marioni, R E; Hedman, Åsa K; Pfeiffer, L et al.

Ingår i Molecular Psychiatry, s. 422-433, 2018

• DOI för A DNA methylation biomarker of alcohol consumption.
• Ladda ner fulltext (pdf) av A DNA methylation biomarker of alcohol consumption.

Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Ingår i Adipocyte, s. 285-296, 2018

• DOI för Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.
• Ladda ner fulltext (pdf) av Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Targeted proteomic analysis of habitual coffee consumption.

Cornelis, M C; Gustafsson, Stefan; Ärnlöv, J; Elmståhl, S et al.

Ingår i Journal of Internal Medicine, s. 200-211, 2018

• DOI för Targeted proteomic analysis of habitual coffee consumption.

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Mendelson, Michael M.; Marioni, Riccardo E.; Joehanes, Roby; Liu, Chunyu et al.

Ingår i PLoS Medicine, 2017

• DOI för Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
• Ladda ner fulltext (pdf) av Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Use of Proteomics To Investigate Kidney Function Decline over 5 Years

Carlsson, Axel C; Ingelsson, Erik; Sundström, Johan; Carrero, Juan Jesus et al.

Ingår i American Society of Nephrology. Clinical Journal, s. 1226-1235, 2017

• DOI för Use of Proteomics To Investigate Kidney Function Decline over 5 Years

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

Strawbridge, Rona J.; Silveira, Angela; den Hoed, Marcel; Gustafsson, Stefan et al.

Ingår i Atherosclerosis, s. 196-204, 2017

• DOI för Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation
• Ladda ner fulltext (pdf) av Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers

Kamble, Prasad G.; Gustafsson, Stefan; Pereira, Maria J; Lundkvist, Per et al.

Ingår i Upsala Journal of Medical Sciences, s. 234-242, 2017

• DOI för Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers
• Ladda ner fulltext (pdf) av Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

Hedman, Åsa K.; Mendelson, Michael M.; Marioni, Riccardo E.; Gustafsson, Stefan et al.

Ingår i Circulation, 2017

• DOI för Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies
• Ladda ner fulltext (pdf) av Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, Ingrid E.; Rienstra, Michiel; Roselli, Carolina; Yin, Xiaoyan et al.

Ingår i Nature Genetics, s. 946-+, 2017

• DOI för Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Rare and low-frequency coding variants alter human adult height

Marouli, Eirini; Graff, Mariaelisa; Medina-Gomez, Carolina; Lo, Ken Sin et al.

Ingår i Nature, s. 186-190, 2017

• DOI för Rare and low-frequency coding variants alter human adult height

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia et al.

Ingår i Diabetes, s. 2888-2902, 2017

• DOI för An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Folkersen, Lasse; Fauman, Eric; Sabater-Lleal, Maria; Strawbridge, Rona J et al.

Ingår i PLOS Genetics, 2017

• DOI för Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
• Ladda ner fulltext (pdf) av Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

Carlsson, Axel C.; Sundström, Johan; Carrero, Juan Jesus; Gustafsson, Stefan et al.

Ingår i European Journal of Preventive Cardiology, s. 340-348, 2017

• DOI för Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

PPARG Pro12Ala variant in relation to adipose tissue metabolism and differentiation: a small genotype-based recall study

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Ingår i Diabetologia, 2017

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Varga, Tibor V.; Kurbasic, Azra; Aine, Mattias; Eriksson, Pontus et al.

Ingår i International Journal of Epidemiology, s. 1211-1222, 2017

• DOI för Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, Amand F.; Swerdlow, Daniel I.; Holmes, Michael V.; Patel, Riyaz S. et al.

Ingår i The Lancet Diabetes and Endocrinology, s. 97-105, 2017

• DOI för PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
• Ladda ner fulltext (pdf) av PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior

Cornelis, Marilyn C; Kacprowski, Tim; Menni, Cristina; Gustafsson, Stefan et al.

Ingår i Human Molecular Genetics, s. 5472-5482, 2016

• DOI för Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Loley, Christina; Alver, Maris; Assimes, Themistocles L.; Bjonnes, Andrew et al.

Ingår i Scientific Reports, 2016

• DOI för No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis
• Ladda ner fulltext (pdf) av No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Kilpeläinen, Tuomas O; Carli, Jayne F Martin; Skowronski, Alicja A; Sun, Qi et al.

Ingår i Nature Communications, 2016

• DOI för Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
• Ladda ner fulltext (pdf) av Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

Ek, Weronica E; Hedman, Åsa K; Enroth, Stefan; Morris, Andrew P et al.

Ingår i Human Molecular Genetics, s. 817-827, 2016

• DOI för Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Yingchang; Day, Felix R; Gustafsson, Stefan; Buchkovich, Martin L et al.

Ingår i Nature Communications, 2016

• DOI för New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
• Ladda ner fulltext (pdf) av New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Walford, Geoffrey A.; Gustafsson, Stefan; Rybin, Denis; Stancakova, Alena et al.

Ingår i Diabetes, s. 3200-3211, 2016

• DOI för Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

Fall, Tove; Salihovic, Samira; Brandmaier, Stefan; Nowak, Christoph et al.

Ingår i Diabetologia, s. 2114-2124, 2016

• DOI för Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts

Nowak, Christoph; Sundström, Johan; Gustafsson, Stefan; Giedraitis, Vilmantas et al.

Ingår i Diabetes, s. 276-284, 2016

• DOI för Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts

Population genetic differentiation of height and body mass index across Europe

Robinson, Matthew R.; Hemani, Gibran; Medina-Gomez, Carolina; Mezzavilla, Massimo et al.

Ingår i Nature Genetics, s. 1357-1362, 2015

• DOI för Population genetic differentiation of height and body mass index across Europe

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

Persson, Jonas; Strawbridge, Rona J.; McLeod, Olga; Gertow, Karl et al.

Ingår i Journal of the American Heart Association, 2015

• DOI för Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease
• Ladda ner fulltext (pdf) av Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Nikpay, Majid; Goel, Anuj; Won, Hong-Hee; Hall, Leanne M. et al.

Ingår i Nature Genetics, s. 1121-1130, 2015

• DOI för A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, Kyle J.; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne et al.

Ingår i Nature Genetics, s. 1415, 2015

• DOI för Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

The impact of low-frequency and rare variants on lipid levels

Surakka, Ida; Horikoshi, Momoko; Magi, Reedik; Sarin, Antti-Pekka et al.

Ingår i Nature Genetics, s. 589-597, 2015

• DOI för The impact of low-frequency and rare variants on lipid levels

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda et al.

Ingår i PLOS Genetics, 2015

• DOI för The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
• Ladda ner fulltext (pdf) av The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

den Hoed, Marcel; Strawbridge, Rona J; Almgren, Peter; Gustafsson, Stefan et al.

Ingår i Atherosclerosis, s. 304-310, 2015

• DOI för GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Wessel, Jennifer; Chu, Audrey Y.; Willems, Sara M.; Wang, Shuai et al.

Ingår i Nature Communications, 2015

• DOI för Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Biological interpretation of genome-wide association studies using predicted gene functions

Pers, Tune H.; Karjalainen, Juha M.; Chan, Yingleong; Westra, Harm-Jan et al.

Ingår i Nature Communications, 2015

• DOI för Biological interpretation of genome-wide association studies using predicted gene functions

New genetic loci link adipose and insulin biology to body fat distribution

Shungin, Dmitry; Winkler, Thomas W; Croteau-Chonka, Damien C; Ferreira, Teresa et al.

Ingår i Nature, s. 187-196, 2015

• DOI för New genetic loci link adipose and insulin biology to body fat distribution

Genetic studies of body mass index yield new insights for obesity biology

Locke, Adam E; Kahali, Bratati; Berndt, Sonja I; Justice, Anne E et al.

Ingår i Nature, s. 197-206, 2015

• DOI för Genetic studies of body mass index yield new insights for obesity biology

Mendelian randomization study of height and risk of colorectal cancer

Thrift, Aaron P.; Gong, Jian; Peters, Ulrike; Chang-Claude, Jenny et al.

Ingår i International Journal of Epidemiology, s. 662-672, 2015

• DOI för Mendelian randomization study of height and risk of colorectal cancer

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood, Andrew R; Esko, Tonu; Yang, Jian; Vedantam, Sailaja et al.

Ingår i Nature Genetics, s. 1173-1186, 2014

• DOI för Defining the role of common variation in the genomic and biological architecture of adult human height

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Arking, Dan E; Pulit, Sara L; Crotti, Lia; van der Harst, Pim et al.

Ingår i Nature Genetics, s. 826-836, 2014

• DOI för Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Quality control and conduct of genome-wide association meta-analyses

Winkler, Thomas W.; Day, Felix R.; Croteau-Chonka, Damien C.; Wood, Andrew R. et al.

Ingår i Nature Protocols, s. 1192-1212, 2014

• DOI för Quality control and conduct of genome-wide association meta-analyses

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, Sonja I.; Gustafsson, Stefan; Maegi, Reedik; Ganna, Andrea et al.

Ingår i Nature Genetics, s. 501-U69, 2013

• DOI för Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
• Ladda ner fulltext (pdf) av Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Discovery and refinement of loci associated with lipid levels

Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti; Peloso, Gina M. et al.

Ingår i Nature Genetics, s. 1274-1283, 2013

• DOI för Discovery and refinement of loci associated with lipid levels

Common variants associated with plasma triglycerides and risk for coronary artery disease

Do, Ron; Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti et al.

Ingår i Nature Genetics, s. 1345-+, 2013

• DOI för Common variants associated with plasma triglycerides and risk for coronary artery disease

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Yaghootkar, Hanieh; Lamina, Claudia; Scott, Robert A.; Dastani, Zari et al.

Ingår i Diabetes, s. 3589-3598, 2013

• DOI för Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics

Hu, Yi-Juan; Berndt, Sonja I.; Gustafsson, Stefan; Ganna, Andrea et al.

Ingår i American Journal of Human Genetics, s. 236-248, 2013

• DOI för Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics

Discovery and replication of new risk markers for 5-year kidney function decline using a targeted multiplex proteomics chip

Ärnlöv, Johan; Ingelsson, Erik; Sundström, Johan; Carrero, J. J. et al.

s. 350-350, 2016