Theodosia Vallianatou

Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Vallianatou, Theodosia; Ilic Balestri, Lorenzo Jacopo; Nilsson, Anna; Zhang, Xiaoqun et al.

Ingår i Chemistry-Methods, 2025

• DOI för Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging
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Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease

Kaya, Ibrahim; Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik et al.

Ingår i npj Parkinson's Disease, 2025

• DOI för Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
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Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI

Bjärterot, Patrik; Nilsson, Anna; Shariatgorji, Reza; Vallianatou, Theodosia et al.

Ingår i Analytical Chemistry, s. 9033-9041, 2025

• DOI för Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI
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Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models

Vallianatou, Theodosia; Tsopelas, Fotios; Tsantili-Kakoulidou, Anna

Ingår i Journal of Chromatography A, 2025

• DOI för Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models
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Inquiry-based Learning of Proteomics and Metabolomics

Nezhyva, Mariya; Aerts, Jordan; Sandbaumhüter, Friederike A.; Vallianatou, Theodosia et al.

Ingår i Journal of Chemical Education, s. 521-529, 2024

• DOI för Inquiry-based Learning of Proteomics and Metabolomics
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Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Vallianatou, Theodosia; Ilic Balestri, Lorenzo Jacopo; Nilsson, Anna; Zhang, Xiaoqun et al.

Ingår i Chemistry-Methods, 2025

• DOI för Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging
• Ladda ner fulltext (pdf) av Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease

Kaya, Ibrahim; Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik et al.

Ingår i npj Parkinson's Disease, 2025

• DOI för Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
• Ladda ner fulltext (pdf) av Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease

Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI

Bjärterot, Patrik; Nilsson, Anna; Shariatgorji, Reza; Vallianatou, Theodosia et al.

Ingår i Analytical Chemistry, s. 9033-9041, 2025

• DOI för Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI
• Ladda ner fulltext (pdf) av Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI

Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models

Vallianatou, Theodosia; Tsopelas, Fotios; Tsantili-Kakoulidou, Anna

Ingår i Journal of Chromatography A, 2025

• DOI för Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models
• Ladda ner fulltext (pdf) av Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models

Inquiry-based Learning of Proteomics and Metabolomics

Nezhyva, Mariya; Aerts, Jordan; Sandbaumhüter, Friederike A.; Vallianatou, Theodosia et al.

Ingår i Journal of Chemical Education, s. 521-529, 2024

• DOI för Inquiry-based Learning of Proteomics and Metabolomics
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Untargeted metabolomics and quantitative analysis of tryptophan metabolites in myalgic encephalomyelitis patients and healthy volunteers: a comparative study using high resolution mass spectrometry

Abujrais, Sandy; Vallianatou, Theodosia; Bergquist, Jonas

2024

• DOI för Untargeted metabolomics and quantitative analysis of tryptophan metabolites in myalgic encephalomyelitis patients and healthy volunteers: a comparative study using high resolution mass spectrometry
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes

Vallianatou, Theodosia; Angerer, Tina B.; Kaya, Ibrahim; Nilsson, Anna et al.

Ingår i ACS Chemical Neuroscience, s. 2822-2829, 2024

• DOI för Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
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Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain

Vallianatou, Theodosia; de Souza Anselmo, Carina; Tsiara, Ioanna; Bechet, Nicholas B. et al.

Ingår i ACS Chemical Neuroscience, s. 1335-1341, 2024

• DOI för Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain
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Rapid Metabolic Profiling of 1 ÎŒL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson's Disease

Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik; Shariatgorji, Reza et al.

Ingår i Analytical Chemistry, s. 18352-18360, 2023

• DOI för Rapid Metabolic Profiling of 1 ÎŒL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson's Disease
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Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model

Kaya, Ibrahim; Nilsson, Anna; Luptakova, Dominika; He, Yachao et al.

Ingår i npj Parkinson's Disease, 2023

• DOI för Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model
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Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data

Vallianatou, Theodosia; Tsopelas, Fotios; Tsantili-Kakoulidou, Anna

Ingår i Molecules, 2022

• DOI för Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data
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Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle

Vallianatou, Theodosia; Bechet, Nicholas B.; Correia, Mario S. P.; Lundgaard, Iben et al.

Ingår i Metabolites, 2022

• DOI för Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle
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Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia

Hulme, Heather; Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Reza et al.

Ingår i npj Parkinson's Disease, 2022

• DOI för Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia
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Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

Fridjonsdottir, Elva; Vallianatou, Theodosia; Mantas, Ioannis; Shariatgorji, Reza et al.

Ingår i ACS Chemical Biology, s. 147-158, 2022

• DOI för Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems
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TAAR1-Dependent and-Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition

Mantas, Ioannis; Vallianatou, Theodosia; Yang, Yunting; Shariatgorji, Mohammadreza et al.

Ingår i Biological Psychiatry, s. 16-27, 2021

• DOI för TAAR1-Dependent and-Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition
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Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain

Vallianatou, Theodosia; Shariatgorji, Reza; Nilsson, Anna; Karlgren, Maria et al.

Ingår i ACS Chemical Neuroscience, s. 1811-1823, 2021

• DOI för Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain
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Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep

Vallianatou, Theodosia; Lin, Weifeng; Bèchet, Nicholas B; Correia, Mario SP et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 3324-3338, 2021

• DOI för Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep
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Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

Ingår i Science Advances, 2021

• DOI för Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia
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Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Luptáková, Dominika; Vallianatou, Theodosia; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i Molecular Psychiatry, s. 7732-7745, 2021

• DOI för Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.
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Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

Ingår i Neurobiology of Disease, 2020

• DOI för Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy
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Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds

Shariatgorji, Mohammadreza; Nilsson, Anna; Strittmatter, Nicole; Vallianatou, Theodosia et al.

Ingår i Journal of the American Society for Mass Spectrometry, s. 2553-2557, 2020

• DOI för Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers

Källback, Patrik; Vallianatou, Theodosia; Nilsson, Anna; Shariatgorji, Mohammadreza et al.

Ingår i Analytical Chemistry, s. 14676-14684, 2020

• DOI för Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers
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Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

Shariatgorji, Mohammadreza; Nilsson, Anna; Fridjonsdottir, Elva; Vallianatou, Theodosia et al.

Ingår i Nature Methods, s. 1021-1028, 2019

• DOI för Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition

Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna; Fridjonsdottir, Elva et al.

Ingår i Neuropsychopharmacology, s. 2091-2098, 2019

• DOI för Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition
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A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability

Vallianatou, Theodosia; Strittmatter, Nicole; Nilsson, Anna; Shariatgorji, Mohammadreza et al.

Ingår i NeuroImage, s. 808-816, 2018

• DOI för A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability

Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

Shariatgorji, Mohammadreza; Strittmatter, Nicole; Nilsson, Anna; Kallbäck, Patrik et al.

Ingår i NeuroImage, s. 129-138, 2016

• DOI för Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

Recent developments in the application of immobilized artificial membrane (IAM) chromatography to drug discovery

Tsopelas, Fotios; Vallianatou, Theodosia; Tsantili-Kakoulidou, Anna

Ingår i Expert Opinion on Drug Discovery, s. 1087-1098, 2024

• DOI för Recent developments in the application of immobilized artificial membrane (IAM) chromatography to drug discovery

Mass Spectrometry Imaging in Drug Development

Nilsson, Anna; Goodwin, Richard J. A.; Shariatgorji, Mohammadreza; Vallianatou, Theodosia et al.

Ingår i Analytical Chemistry, s. 1437-1455, 2015

• DOI för Mass Spectrometry Imaging in Drug Development

Advanced Mass Spectrometry Imaging in Neuropharmacology

Vallianatou, Theodosia

2019

• Ladda ner fulltext (pdf) av Advanced Mass Spectrometry Imaging in Neuropharmacology

Imaging age-induced perturbations of mitochondrial function, neurotransmission and lipid signaling in specific brain regions

Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna; Karlgren, Maria et al.

Imaging aging effects on the catecholamine, serotonin, and histamine neurotransmitter systems in specific brain regions

Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna et al.

Mass spectrometry imaging of multiple basal ganglia neuropeptides shows abnormal neuropeptide processing associated with L-DOPA-induced dyskinesia in a primate model of Parkinson’s disease

Hulme, Heather; Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Mohammadreza et al.

Rapid metabolic profiling of one microliter crude CSF by MALDI MS can differentiate de novo Parkinson’s disease

Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik; Shariatgorji, Reza et al.

Mass spectrometry imaging reveals brain-region specific changes in metabolism and acetylcholine levels in experimental Parkinson’s disease and L-DOPA-induced dyskinesia

Fridjonsdottir, Elva; Vallianatou, Theodosia; Aerts, Jordan T.; Mantas, Ioannis et al.

Met-ID 2.0: High Confidence Annotation with Collision Cross Section Predictions

Bjärterot, Patrik; Vallianatou, Theodosia; Nilsson, Anna; Shariatgorji, Reza et al.