Aleksei Kabedev

Lipid packing contributes to the confinement of caveolae to the plasma membrane

Larsson, Elin; Kabedev, Aleksei; Pace, Hudson; Lindwall, Jakob et al.

Ingår i eLIFE, 2026

• DOI för Lipid packing contributes to the confinement of caveolae to the plasma membrane
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Indomethacin forms elusive nanoparticles with calcium in situ causing enhanced permeation across a biomimetic barrier

Tonning, Mikkel Hojmark; Bauer-Brandl, Annette; Brandl, Martin; Kabedev, Aleksei et al.

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Indomethacin forms elusive nanoparticles with calcium in situ causing enhanced permeation across a biomimetic barrier
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Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach

Kabedev, Aleksei; Højmark Tønning, Mikkel; Teleki, Alexandra; Bauer-Brandl, Annette et al.

Ingår i Colloids and Surfaces B, 2025

• DOI för Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach
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Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations

Parrow, Albin; Kabedev, Aleksei; Larsson, Per; Johansson, Pernilla et al.

Ingår i Journal of Controlled Release, 2024

• DOI för Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
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Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Kabedev, Aleksei; Bergström, Christel A. S.; Larsson, Per

Ingår i Journal of Computer-Aided Molecular Design, 2024

• DOI för Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
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Lipid packing contributes to the confinement of caveolae to the plasma membrane

Larsson, Elin; Kabedev, Aleksei; Pace, Hudson; Lindwall, Jakob et al.

Ingår i eLIFE, 2026

• DOI för Lipid packing contributes to the confinement of caveolae to the plasma membrane
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Indomethacin forms elusive nanoparticles with calcium in situ causing enhanced permeation across a biomimetic barrier

Tonning, Mikkel Hojmark; Bauer-Brandl, Annette; Brandl, Martin; Kabedev, Aleksei et al.

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Indomethacin forms elusive nanoparticles with calcium in situ causing enhanced permeation across a biomimetic barrier
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Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach

Kabedev, Aleksei; Højmark Tønning, Mikkel; Teleki, Alexandra; Bauer-Brandl, Annette et al.

Ingår i Colloids and Surfaces B, 2025

• DOI för Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach
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Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations

Parrow, Albin; Kabedev, Aleksei; Larsson, Per; Johansson, Pernilla et al.

Ingår i Journal of Controlled Release, 2024

• DOI för Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
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Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Kabedev, Aleksei; Bergström, Christel A. S.; Larsson, Per

Ingår i Journal of Computer-Aided Molecular Design, 2024

• DOI för Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
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Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

Zhuo, Xuezhi; Foderà, Vito; Larsson, Per; Schaal, Zarah et al.

Ingår i European Journal of Pharmaceutical Sciences, 2024

• DOI för Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
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Intrinsic lipolysis rate for systematic design of lipid-based formulations

Jacobsen, Ann-Christin; Kabedev, Aleksei; Sinko, Patrick D.; Palm, Johan E. et al.

Ingår i Drug Delivery and Translational Research, s. 1288-1304, 2023

• DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations
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Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

Zhuo, Xuezhi; Sener, Zeyneb; Kabedev, Aleksei; Zhao, Min et al.

Ingår i Molecular Pharmaceutics, s. 5206-5213, 2023

• DOI för Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers

Hossain, Md Shakhawath; Parrow, Albin; Kabedev, Aleksei; Kneiszl, Rosita C. et al.

Ingår i Processes, s. 29, 2022

• DOI för Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers
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Membrane insertion mechanism of the caveola coat protein Cavin1

Liu, Kang-Cheng; Pace, Hudson; Larsson, Elin; Hossain, Md Shakhawath et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI för Membrane insertion mechanism of the caveola coat protein Cavin1
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Endothelial glycocalyx permeability for nanoscale solutes

Kabedev, Aleksei; Lobaskin, Vladimir

Ingår i Nanomedicine, s. 979-996, 2022

• DOI för Endothelial glycocalyx permeability for nanoscale solutes
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Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

Kabedev, Aleksei; Zhuo, Xuezhi; Leng, Donglei; Foderà, Vito et al.

Ingår i Molecular Pharmaceutics, s. 3922-3933, 2022

• DOI för Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
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Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation

Kabedev, Aleksei; Hossain, Shakhawath; Hubert, Madlen; Larsson, Per et al.

Ingår i Journal of Pharmaceutical Sciences, s. 176-185, 2021

• DOI för Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
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Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations

Edueng, Khadijah; Kabedev, Aleksei; Ekdahl, Alyssa; Mahlin, Denny et al.

Ingår i International Journal of Pharmaceutics, 2021

• DOI för Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations

Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development

Salo-Ahen, Outi M. H.; Alanko, Ida; Bhadane, Rajendra; Bonvin, Alexandre M. J. J. et al.

Ingår i Processes, 2021

• DOI för Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development
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Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning

Hossain, Md Shakhawath; Kabedev, Aleksei; Parrow, Albin; Bergström, Christel et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 46-55, 2019

• DOI för Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
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Molecular Dynamics Simulations as a Tool to Understand Drug Solubilization in Pharmaceutical Systems

Kabedev, Aleksei; Hossain, Shakhawath; Larsson, Per

Ingår i Comprehensive Computational Chemistry, Elsevier, 2023

• DOI för Molecular Dynamics Simulations as a Tool to Understand Drug Solubilization in Pharmaceutical Systems

The influence of drug loading and drug-polymer interactions on physical stability and supersaturation of spray-dried solid dispersions

Edueng, Khadijah; Kabedev, Aleksei; Ekdahl, Alyssa; Mahlin, Denny et al.