Richard Marsell
Specialistläkare vid Institutionen för kirurgiska vetenskaper; Ortopedi och Handkirurgi
- Mobiltelefon:
- 070-584 02 47
- E-post:
- richard.marsell@uu.se
- Besöksadress:
- Akademiska sjukhuset, ingång 61, 6 tr
751 85 UPPSALA - Postadress:
- Akademiska sjukhuset, ingång 61, 6 tr
751 85 UPPSALA
- Akademiska meriter:
- MD, PhD
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Kort presentation
Denna text finns inte på svenska, därför visas den engelska versionen.
Richard Marsell is an appreciated orthopedic surgeon, researcher and lecturer. His main focus is pediatric orthopedics, bone lengthening surgery and bone regeneration techniques and he is engaged in both clinical and pre-clinical research.
Biografi
Denna text finns inte på svenska, därför visas den engelska versionen.
Dr. Marsell is an active clinical orthopedic surgeon, and a clinical and preclinical researcher in orthopedics. He is affiliated with Uppsala University Hospital (Akademiska Sjukhuset) and Uppsala University. He is born in Östersund, Sweden, in 1975 and moved to Uppsala for medical school in 1997 where he earned his medical degree in 2003. In medical school he had several international rotations, such as the Royal Perth Hospital, Western Australia University and Academisch Medisch Centrum, Amsterdam University.
He performed his internship at Uppsala University Hospital followed by a residency at the Orthopedic Unit. Parallel with his other commitments, he underwent a PhD-program and defended his thesis on phosphate regulation and genetic bone disease (XLH, ADHR and TIO) in 2008. With his work he was part of discovering the phosphate regulating hormone FGF23, and awarded with both “The best medical thesis of the year at Uppsala University” and “The best endocrine thesis of the year in Sweden” in 2008. Part of his PhD-studies was performed at Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Between 2008 and 2010 he did a Post Doc on bone regeneration in Dr. Thomas A. Einhorn and Louis C. Gerstenfeld’s Orthopedic Laboratory, Boston Medical Center, Boston University. During his stay he also had the opportunity to attend weekly clinical rounds and lectures led by Dr. Paul Tornetta or Dr. Einhorn. The stay in Boston earned him both original articles, reviews, a book chapter, invaluable clinical discussions and international connections.
Back in Sweden in 2010 he finished his residency by 2011, followed by a combined position in adult trauma and pediatric orthopedics. From 2012 and onwards, he is a consultant orthopedic surgeon at the Pediatric Orthopedic Department at Uppsala University Children’s Hospital (Akademiska Barnsjukhuset). He currently works with both orthopedic trauma surgery and reconstructive surgery with a main focus on bone lengthening. His ongoing research is focused on optimization of osteodistraction and bone regeneration.
As a clinically active surgeon and researcher, Dr. Marsell always promote and defend evidence based medicine and high pedagogic standards, and holds a prominent position as a lecturer and course leader on different programs at Uppsala University.
Publikationer
Senaste publikationer
- Epidemiology of proximal and diaphyseal humeral fractures in children (2022)
- Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration (2018)
- Successful treatment of a humeral capitulum osteonecrosis with bone morphogenetic protein-7 combined with autologous bone grafting (2014)
- Bisphosphonate-Linked Hyaluronic Acid Hydrogel Sequesters and Enzymatically Releases Active Bone Morphogenetic Protein-2 for Induction of Osteogenic Differentiation (2013)
- In vivo performance of a BP-linked hyaluronan-based hydrogel as carrier of bone morphogenetic protein-2 (2013)
Alla publikationer
Artiklar
- Epidemiology of proximal and diaphyseal humeral fractures in children (2022)
- Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration (2018)
- Successful treatment of a humeral capitulum osteonecrosis with bone morphogenetic protein-7 combined with autologous bone grafting (2014)
- Bisphosphonate-Linked Hyaluronic Acid Hydrogel Sequesters and Enzymatically Releases Active Bone Morphogenetic Protein-2 for Induction of Osteogenic Differentiation (2013)
- Rats treated with AZD2858, a GSK3 inhibitor, heal fractures rapidly without endochondral bone formation (2013)
- GSK-3 inhibition by an orally active small molecule increases bone mass in rats (2012)
- The biology of fracture healing (2011)
- Circulating fibroblast growth factor-23 is associated with fat mass and dyslipidemia in two independent cohorts of elderly individuals (2011)
- Emerging bone healing therapies (2010)
- The phosphate regulating hormone fibroblast growth factor-23 (2010)
- Relation between fibroblast growth factor-23, body weight and bone mineral density in elderly men (2009)
- Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23 (2008)
- Osteoclast polarization is not required for degradation of bone matrix in rachitic FGF23 transgenic mice (2008)
- Fibroblast growth factor-23 is associated with parathyroid hormone and renal function in a population-based cohort of elderly men (2008)
- Gene Expression Analysis of Kidneys From Transgenic Mice Expressing Fibroblast Growth Factor-23 (2008)
- Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells (2007)
- Mice expressing a constitutively active PTH/PTHrP receptor in osteoblasts show reduced callus size but normal callus morphology during fracture healing (2007)
- Transgenic mice expressing Fibroblast Growth Factor-23 under the control of the α1 (I) collagen promoter exhibit growth retardation, Osteomalacia and disturbed phosphate homeostasis (2004)
- Non-invasive tri-modal visualisation of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept.
- Association of FGF23 to bone mineral density is dependent on total body fat mass