Suparna Sanyal

Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel S.D.; Sihlbom Wallem, Carina et al.

Ingår i Nature Communications, 2025

• DOI för Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis
• Ladda ner fulltext (pdf) av Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel; Sihlbom Wallem, Carina et al.

Ingår i Nature Communications, 2025

• DOI för Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

González-López, Adrián; Larsson, Daniel S. D.; Koripella, Ravi Kiran; Cain, Brett N. et al.

Ingår i Scientific Reports, 2024

• DOI för Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
• Ladda ner fulltext (pdf) av Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Pal, Aditya Kumar; Ghorai, Dipankar; Ge, Xueliang; Sarkar, Biplab et al.

Ingår i FEMS Microbiology Letters, 2024

• DOI för Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Seely, Savannah M.; Parajuli, Narayan P.; De Tarafder, Arindam; Ge, Xueliang et al.

Ingår i Nature Communications, 2023

• DOI för Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
• Ladda ner fulltext (pdf) av Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel S.D.; Sihlbom Wallem, Carina et al.

Ingår i Nature Communications, 2025

• DOI för Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis
• Ladda ner fulltext (pdf) av Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel; Sihlbom Wallem, Carina et al.

Ingår i Nature Communications, 2025

• DOI för Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

González-López, Adrián; Larsson, Daniel S. D.; Koripella, Ravi Kiran; Cain, Brett N. et al.

Ingår i Scientific Reports, 2024

• DOI för Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
• Ladda ner fulltext (pdf) av Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Pal, Aditya Kumar; Ghorai, Dipankar; Ge, Xueliang; Sarkar, Biplab et al.

Ingår i FEMS Microbiology Letters, 2024

• DOI för Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Seely, Savannah M.; Parajuli, Narayan P.; De Tarafder, Arindam; Ge, Xueliang et al.

Ingår i Nature Communications, 2023

• DOI för Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
• Ladda ner fulltext (pdf) av Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria

Parajuli, Narayan Prasad; Emmerich, Andrew G; Mandava, Chandra Sekhar; Pavlov, Michael Y. et al.

Ingår i Nature Communications, 2023

• DOI för Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria
• Ladda ner fulltext (pdf) av Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria

Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli

Singh, Sudhir; Lahry, Kuldeep; Mandava, Chandra Sekhar; Singh, Jitendra et al.

Ingår i RNA Biology, s. 681-692, 2023

• DOI för Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
• Ladda ner fulltext (pdf) av Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli

Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Majumdar, Soneya; Emmerich, Andrew G; Krakovka, Sascha; Mandava, Chandra Sekhar et al.

Ingår i Nucleic Acids Research, s. 3436-3451, 2023

• DOI för Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
• Ladda ner fulltext (pdf) av Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Real-time measurements of aminoglycoside effects on protein synthesis in live cells

Aguirre Rivera, Javier; Larsson, Jimmy; Volkov, Ivan; Seefeldt, A. Carolin et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2021

• DOI för Real-time measurements of aminoglycoside effects on protein synthesis in live cells
• Ladda ner fulltext (pdf) av Real-time measurements of aminoglycoside effects on protein synthesis in live cells

Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation

Kim, Changil; Holm, Mikael; Mandava, Chandra Sekhar; Sanyal, Suparna

Ingår i RNA Biology, s. 2363-2375, 2021

• DOI för Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation
• Ladda ner fulltext (pdf) av Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation

Repurposing tRNAs for nonsense suppression

Albers, Suki; Beckert, Bertrand; Matthies, Marco C.; Mandava, Chandra Sekhar et al.

Ingår i Nature Communications, 2021

• DOI för Repurposing tRNAs for nonsense suppression
• Ladda ner fulltext (pdf) av Repurposing tRNAs for nonsense suppression

Kinetic Analysis Suggests Evolution of Ribosome Snecificity in Modern Elongation Factor-Tus from "Generalist" Ancestors

De Tarafder, Arindam; Parajuli, Narayan Prasad; Majumdar, Soneya; Kacar, Betul et al.

Ingår i Molecular biology and evolution, s. 3436-3444, 2021

• DOI för Kinetic Analysis Suggests Evolution of Ribosome Snecificity in Modern Elongation Factor-Tus from "Generalist" Ancestors

Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis

Eaglesfield, Ross; Madsen, Mary Ann; Sanyal, Suparna; Reboud, Julien et al.

Ingår i iScience, 2021

• DOI för Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis
• Ladda ner fulltext (pdf) av Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis

GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors

Pundir, Shreya; Ge, Xueliang; Sanyal, Suparna

Ingår i Journal of Biological Chemistry, 2021

• DOI för GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors
• Ladda ner fulltext (pdf) av GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors

Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin

Parajuli, Narayan Prasad; Mandava, Chandra Sekhar; Pavlov, Michael; Sanyal, Suparna

Ingår i Nucleic Acids Research, s. 6880-6892, 2021

• DOI för Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin

Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s

Pang, Yanhong; Kovachev, Petar Stefanov; Sanyal, Suparna

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s
• Ladda ner fulltext (pdf) av Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s

Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation

Wang, Li; Wanqiu, Li; Ge, Xueliang; Kaige, Yan et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15609-15619, 2020

• DOI för Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation

Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence

Abdalaal, Hind; Pundir, Shreya; Ge, Xueliang; Sanyal, Suparna et al.

Ingår i Molecular biology and evolution, s. 2918-2930, 2020

• DOI för Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence
• Ladda ner fulltext (pdf) av Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence

Selective translation by alternative bacterial ribosomes

Chen, Yu-Xiang; Xu, Zhi-Yu; Ge, Xueliang; Hong, Jia-Yao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 19487-19496, 2020

• DOI för Selective translation by alternative bacterial ribosomes
• Ladda ner fulltext (pdf) av Selective translation by alternative bacterial ribosomes

RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

Kovachev, Petar Stefanov; Gomes, Mariana P. B.; Cordeiro, Yraima; Ferreira, Natalia C. et al.

Ingår i Scientific Reports, 2019

• DOI för RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
• Ladda ner fulltext (pdf) av RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation

Holm, Mikael; Mandava, Chandra Sekhar; Ehrenberg, Måns; Sanyal, Suparna

Ingår i eLIFE, 2019

• DOI för The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation
• Ladda ner fulltext (pdf) av The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation

Inhibition of translation termination by small molecules targeting ribosomal release factors

Ge, Xueliang; Oliveira, Ana; Hjort, Karin; Bergfors, Terese et al.

Ingår i Scientific Reports, 2019

• DOI för Inhibition of translation termination by small molecules targeting ribosomal release factors
• Ladda ner fulltext (pdf) av Inhibition of translation termination by small molecules targeting ribosomal release factors

Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)

Fislage, Marcus; Zhang, Jingji; Brown, Zuben Patrick; Mandava, Chandra Sekhar et al.

Ingår i Nucleic Acids Research, s. 5861-5874, 2018

• DOI för Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)
• Ladda ner fulltext (pdf) av Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)

Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers

Li, Zhifei; Ge, Xueliang; Zhang, Yixiao; Zheng, Lvqin et al.

Ingår i Protein & Cell, s. 384-388, 2018

• DOI för Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers
• Ladda ner fulltext (pdf) av Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers

Binding Characteristics of Anticancer Drug Doxorubicin with Two-Dimensional Graphene and Graphene Oxide: Insights from Density Functional Theory Calculations and Fluorescence Spectroscopy

Vovusha, Hakkim; Banerjee, Debapriya; Yadav, Manoj Kumar; Perrozzi, Francesco et al.

Ingår i The Journal of Physical Chemistry C, s. 21031-21038, 2018

• DOI för Binding Characteristics of Anticancer Drug Doxorubicin with Two-Dimensional Graphene and Graphene Oxide: Insights from Density Functional Theory Calculations and Fluorescence Spectroscopy

Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones

Mishra, Abhishek Kumar; Morgon, Nelson Henrique; Sanyal, Suparna; de Souza, Aguinaldo Robinson et al.

Ingår i Advanced Synthesis and Catalysis, s. 3930-3939, 2018

• DOI för Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones

Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association

Ge, Xueliang; Mandava, Chandra Sekhar; Lind, Christoffer; Åqvist, Johan et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 4649-4654, 2018

• DOI för Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association

Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein

Kacar, Betuel; Ge, Xueliang; Sanyal, Suparna; Gaucher, Eric A.

Ingår i Journal of Molecular Evolution, s. 69-84, 2017

• DOI för Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein
• Ladda ner fulltext (pdf) av Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein

A genetically encoded fluorescent tRNA is active in live-cell protein synthesis

Masuda, Isao; Igarashi, Takao; Sakaguchi, Reiko; Nitharwal, Ram G. et al.

Ingår i Nucleic Acids Research, s. 4081-4093, 2017

• DOI för A genetically encoded fluorescent tRNA is active in live-cell protein synthesis
• Ladda ner fulltext (pdf) av A genetically encoded fluorescent tRNA is active in live-cell protein synthesis

New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.

Qiang, Xiaoling; Liotta, Anthony S; Shiloach, Joseph; Gutierrez, J C et al.

Ingår i npj Biofilms and Microbiomes, 2017

• DOI för New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.
• Ladda ner fulltext (pdf) av New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.

Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

Chan, Sherwin; Frasch, Alejandra; Mandava, Chandra Sekhar; Ch'ng, Jun-Hong et al.

Ingår i Nature Microbiology, 2017

• DOI för Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.

Kovachev, Petar Stefanov; Banerjee, Debapriya; Rangel, Luciana Pereira; Eriksson, Jonny et al.

Ingår i Journal of Biological Chemistry, s. 9345-9357, 2017

• DOI för Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.

R213I mutation in release factor 2 (RF2) is one step forward for engineering an omnipotent release factor in bacteria Escherichia coli

Korkmaz, Gürkan; Sanyal, Suparna

Ingår i Journal of Biological Chemistry, s. 15134-15142, 2017

• DOI för R213I mutation in release factor 2 (RF2) is one step forward for engineering an omnipotent release factor in bacteria Escherichia coli

Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli

Mohapatra, Sonisilpa; Choi, Heejun; Ge, Xueliang; Sanyal, Suparna et al.

Ingår i mBio, 2017

• DOI för Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli
• Ladda ner fulltext (pdf) av Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli

Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis

Degiacomi, Giulia; Personne, Yoann; Mondesert, Guillaume; Ge, Xueliang et al.

Ingår i Tuberculosis, s. 95-101, 2016

• DOI för Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

Holm, Mikael; Borg, Anneli; Ehrenberg, Måns; Sanyal, Suparna

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 978-983, 2016

• DOI för Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

Li, Wen; Liu, Zheng; Koripella, Ravi Kiran; Langlois, Robert et al.

Ingår i Science Advances, 2015

• DOI för Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G
• Ladda ner fulltext (pdf) av Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate

Koripella, Ravi Kiran; Holm, Mikael; Dourado, Daniel; Mandava, Chandra Sekhar et al.

Ingår i Scientific Reports, 2015

• DOI för A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate
• Ladda ner fulltext (pdf) av A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate

Fusidic Acid Targets Elongation Factor G in Several Stages of Translocation on the Bacterial Ribosome

Borg, Anneli; Holm, Mikael; Shiroyama, Ikue; Hauryliuk, Vasili et al.

Ingår i Journal of Biological Chemistry, s. 3440-3454, 2015

• DOI för Fusidic Acid Targets Elongation Factor G in Several Stages of Translocation on the Bacterial Ribosome

Electronic structure and spectroscopic properties of 6-aminophenanthridine and its derivatives: Insights from density functional theory

Vovusha, Hakkim; Banerjee, Debapriya; Oumata, Nassima; Sanyal, Biplab et al.

Ingår i International Journal of Quantum Chemistry, s. 846-852, 2015

• DOI för Electronic structure and spectroscopic properties of 6-aminophenanthridine and its derivatives: Insights from density functional theory

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

Zhang, Yanqing; Mandava, Chandra Sekhar; Cao, Wei; Li, Xiaojing et al.

Ingår i Nature Structural & Molecular Biology, s. 906-913, 2015

• DOI för HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

Characterizing an engineered release factor capable of reading all three stop codons

Korkmaz, Gürkan; Lind, Christoffer; Åqvist, Johan; Sanyal, Suparna

Ingår i The FASEB Journal, 2014

Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase

Feng, Boya; Mandava, Chandra Sekhar; Guo, Qiang; Wang, Jie et al.

Ingår i PLoS biology, 2014

• DOI för Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase
• Ladda ner fulltext (pdf) av Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase

Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence

Chai, Qian; Singh, Bhupender; Peisker, Kristin; Metzendorf, Nicole et al.

Ingår i Journal of Biological Chemistry, s. 11342-11352, 2014

• DOI för Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence

Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

Korkmaz, Gürkan; Holm, Mikael; Wiens, Tobias; Sanyal, Suparna

Ingår i Journal of Biological Chemistry, s. 30334-30342, 2014

• DOI för Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

Structure-Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost alpha 2-Adrenergic Receptor Agonistic Activity

Nguyen, Phu Hai; Hammoud, Hassan; Halliez, Sophie; Pang, Yanhong et al.

Ingår i ACS Chemical Neuroscience, s. 1075-1082, 2014

• DOI för Structure-Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost alpha 2-Adrenergic Receptor Agonistic Activity

Spectroscopic and DFT studies on 6-Aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA

Banerjee, Debapriya; Vovusha, Hakkim; Pang, Yanhong; Oumata, Nassima et al.

Ingår i Biochimie, s. 194-199, 2014

• DOI för Spectroscopic and DFT studies on 6-Aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA

Interaction of Nucleobases and Aromatic Amino Acids with Graphene Oxide and Graphene Flakes

Vovusha, Hakkim; Sanyal, Suparna; Sanyal, Biplab

Ingår i The Journal of Physical Chemistry Letters, s. 3710-3718, 2013

• DOI för Interaction of Nucleobases and Aromatic Amino Acids with Graphene Oxide and Graphene Flakes

The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

Oumata, Nassima; Nguyen, Phu Hai; Beringue, Vincent; Soubigou, Flavie et al.

Ingår i PLOS ONE, 2013

• DOI för The Toll-Like Receptor Agonist Imiquimod Is Active against Prions
• Ladda ner fulltext (pdf) av The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Pang, Yanhong; Kurella, Sriram; Voisset, Cecile; Samanta, Dibyendu et al.

Ingår i Journal of Biological Chemistry, s. 19081-19089, 2013

• DOI för The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1

Pallesen, Jesper; Hashem, Yaser; Korkmaz, Gürkan; Koripella, Ravi Kiran et al.

Ingår i eLife, 2013

• DOI för Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1
• Ladda ner fulltext (pdf) av Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1

Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G

Mandava, Chandra Sekhar; Peisker, Kristin; Ederth, Josefine; Kumar, Ranjeet et al.

Ingår i Nucleic Acids Research, s. 2054-2064, 2012

• DOI för Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G
• Ladda ner fulltext (pdf) av Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G

Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling

Guo, Xiaohu; Peisker, Kristin; Bäckbro, Kristina; Chen, Yang et al.

Ingår i Open Biology, s. 120016, 2012

• DOI för Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling

Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureus

Koripella, Ravi Kiran; Chen, Yang; Peisker, Kristin; Koh, Cha San et al.

Ingår i Journal of Biological Chemistry, s. 30257-30267, 2012

• DOI för Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureus

Mechanism and Rates of Exchange of L7/L12 between Ribosomes and the Effects of Binding EF-G

Deroo, Stephanie; Hyung, Suk-Joon; Marcoux, Julien; Gordiyenko, Yuliya et al.

Ingår i ACS Chemical Biology, s. 1120-1127, 2012

• DOI för Mechanism and Rates of Exchange of L7/L12 between Ribosomes and the Effects of Binding EF-G

Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Dos Reis, Suzana; Pang, Yanhong; Vishnu, Neelanjan; Voisset, Cécile et al.

Ingår i Biochimie, s. 1047-1054, 2011

• DOI för Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Tobin, Christina; Mandava, Chandra Sekhar; Ehrenberg, Måns; Andersson, Dan I et al.

Ingår i Journal of Molecular Biology, s. 767-776, 2010

• DOI för Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

Chen, Yang; Koripella, Ravi Kiran; Sanyal, Suparna; Selmer, Maria

Ingår i The FEBS Journal, s. 3789-3803, 2010

• DOI för Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

The Ribosomal Stalk Plays a Key Role in IF2-Mediated Association of the Ribosomal Subunits

Huang, Chenhui; Mandava, Chandra Sekhar; Sanyal, Suparna

Ingår i Journal of Molecular Biology, s. 145-153, 2010

• DOI för The Ribosomal Stalk Plays a Key Role in IF2-Mediated Association of the Ribosomal Subunits

A single-step method for purification of active His-tagged ribosomes from a genetically engineered Escherichia coli

Ederth, Josefine; Mandava, Chandra Sekhar; Dasgupta, Santanu; Sanyal, Suparna

Ingår i Nucleic Acids Research, 2009

• DOI för A single-step method for purification of active His-tagged ribosomes from a genetically engineered Escherichia coli

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

Li, Wen; Agirrezabala, Xabier; Lei, Jianlin; Bouakaz, Lamine et al.

Ingår i EMBO Journal, s. 3322-3331, 2008

• DOI för Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Tribouillard-Tanvier, Deborah; Dos Reis, Suzana; Gug, Fabienne; Voisset, Cecile et al.

Ingår i PloS one, 2008

• DOI för Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain

Helgstrand, Magnus; Mandava, Chandra S.; Mulder, Frans A. A.; Liljas, Anders et al.

Ingår i Journal of Molecular Biology, s. 468-479, 2007

• DOI för The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

Gao, Haixiao; Zhou, Zhihong; Rawat, Urmila; Huang, Chenhui et al.

Ingår i Cell, s. 929-941, 2007

• DOI för RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

Immobilized β-cyclodextrin polymer coupled to agarose gel properly refolding recombinant Staphylococcus aureus elongation factor-G in combination with detergent micelle

Li, Jing-Jing; Venkataramana, Musturi; Sanyal, Suparna; Janson, Jan-Christer et al.

Ingår i Protein Expression and Purification, s. 72-79, 2006

Synthesis and biological evaluation of photoaffinity labeled fusidic acid analogues.

Riber, Ditte; Venkataramana, Musturi; Sanyal, Suparna; Duvold, Tore

Ingår i J Med Chem, s. 1503-5, 2006

A mild hydrophobic interaction chromatography involving polyethylene glycol immobilized to agarose media refolding recombinant Staphylococcus aureus elongation factor G

Li, Jing-Jing; Venkataramana; Wang, Ai-Qing; Sanyal, Suparna et al.

Ingår i Protein Expression and Purification, s. 327-335, 2005

Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading.

Sörensen, Michael A; Elf, Johan; Bouakaz, Elli; Tenson, Tanel et al.

Ingår i J Mol Biol, s. 16-24, 2005

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure.

Vestergaard, Bente; Sanyal, Suparna; Roessle, Manfred; Mora, Liliana et al.

Ingår i Mol Cell, s. 929-38, 2005

p53 Isoforms as Cancer Biomarkers and Therapeutic Targets

Zhao, Liuqun; Sanyal, Suparna

Ingår i Cancers, 2022

• DOI för p53 Isoforms as Cancer Biomarkers and Therapeutic Targets
• Ladda ner fulltext (pdf) av p53 Isoforms as Cancer Biomarkers and Therapeutic Targets

Modulation of p53 and prion protein aggregation by RNA

Cordeiro, Yraima; Vieira, Tuane; Kovachev, Petar Stefanov; Sanyal, Suparna et al.

Ingår i Biochimica et Biophysica Acta - Proteins and Proteomics, s. 933-940, 2019

• DOI för Modulation of p53 and prion protein aggregation by RNA

The enigmatic ribosomal stalk

Liljas, Anders; Sanyal, Suparna

Ingår i Quarterly reviews of biophysics (Print), 2018

• DOI för The enigmatic ribosomal stalk

p53 Isoforms and Their Implications in Cancer

Vieler, Maximilian; Sanyal, Suparna

Ingår i Cancers, 2018

• DOI för p53 Isoforms and Their Implications in Cancer
• Ladda ner fulltext (pdf) av p53 Isoforms and Their Implications in Cancer

p53 Isoforms and Their Implications in Cancer

Vieler, Maximilian; Sanyal, Suparna

Ingår i Cancers, 2018

• DOI för p53 Isoforms and Their Implications in Cancer
• Ladda ner fulltext (pdf) av p53 Isoforms and Their Implications in Cancer

Protein Folding Activity of the Ribosome (PFAR): A Target for Antiprion Compounds

Banerjee, Debapriya; Sanyal, Suparna

Ingår i Viruses, s. 3907-3924, 2014

• DOI för Protein Folding Activity of the Ribosome (PFAR): A Target for Antiprion Compounds
• Ladda ner fulltext (pdf) av Protein Folding Activity of the Ribosome (PFAR): A Target for Antiprion Compounds

Initiation of bacterial protein synthesis with wild type and novel mutants of initiation factor

Pavlov, Michael Y.; Sanyal, Suparna; Ehrenberg, Måns

Ingår i Ribosomes, s. 129-141, 2011

Distribution of ribosomes in action and at rest in Escherichia coli: involvement of bacterial cytoskeleton

Chai, Qian; Singh, Bhupender; Peisker, Kristin; Dasgupta, Santanu et al.

Essential role of Histidine 92 in elongation factor-G in GTP hydrolysis and inorganic phosphate release during elongation of protein synthesis

Koripella, Ravi Kiran; Holm, Mikael; Sanyal, Suparna

Real-time measurements of aminoglycoside effects on protein synthesis in live cells

Aguirre Rivera, Javier; Larsson, Jimmy; Seefeldt, A. Carolin; Sanyal, Suparna et al.

An extended C-terminal tail of the ribosomal protein S13 modulates the speed of ribosomal translocation.

Kim, Chang-il; Koripella, Ravi Kiran; Aguirre Rivera, Javier; Ge, Xueliang et al.

The compensatory mechanism of a naturally-evolved E167K RF2 counteracting the loss of RF1 in bacteria

Pundir, Shreya; Larsson, Daniel; Selmer, Maria; Sanyal, Suparna

The end of the beginning: structural studies of ribosomal proteins

Chandra Sanyal, S; Liljas, A

Ingår i Curr Opin Struct Biol, s. 633-636, 2000