Ana Godec

Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment

Metzendorf, Nicole G.; Godec, Ana; Petrovic, Alex; Chourlia, Aikaterini et al.

Ingår i Biomedicine and Pharmacotherapy, 2025

• DOI för Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment
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Updated transient gene expression protocol in Expi293F cells using PEI

Hederoth, Gustaf; de la Rosa, Andrés; Godec, Ana; Aguilar, Ximena et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Updated transient gene expression protocol in Expi293F cells using PEI
• Ladda ner fulltext (pdf) av Updated transient gene expression protocol in Expi293F cells using PEI

Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration

de la Rosa, Andrés; Metzendorf, Nicole G.; Efverström, Jonathan; Godec, Ana et al.

Ingår i Neurotherapeutics, 2025

• DOI för Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration
• Ladda ner fulltext (pdf) av Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration

A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

Petersen, Inga; Morrison, Jamie I.; Petrovic, Alex; Babic, Neira et al.

Ingår i Scientific Reports, 2024

• DOI för A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro
• Ladda ner fulltext (pdf) av A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Petersen, Inga; Godec, Ana; Ranjbarian, Farahnaz; Hofer, Anders et al.

Ingår i PLOS ONE, 2024

• DOI för A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils
• Ladda ner fulltext (pdf) av A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment

Metzendorf, Nicole G.; Godec, Ana; Petrovic, Alex; Chourlia, Aikaterini et al.

Ingår i Biomedicine and Pharmacotherapy, 2025

• DOI för Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment
• Ladda ner fulltext (pdf) av Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment

Updated transient gene expression protocol in Expi293F cells using PEI

Hederoth, Gustaf; de la Rosa, Andrés; Godec, Ana; Aguilar, Ximena et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Updated transient gene expression protocol in Expi293F cells using PEI
• Ladda ner fulltext (pdf) av Updated transient gene expression protocol in Expi293F cells using PEI

Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration

de la Rosa, Andrés; Metzendorf, Nicole G.; Efverström, Jonathan; Godec, Ana et al.

Ingår i Neurotherapeutics, 2025

• DOI för Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration
• Ladda ner fulltext (pdf) av Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration

A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

Petersen, Inga; Morrison, Jamie I.; Petrovic, Alex; Babic, Neira et al.

Ingår i Scientific Reports, 2024

• DOI för A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro
• Ladda ner fulltext (pdf) av A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Petersen, Inga; Godec, Ana; Ranjbarian, Farahnaz; Hofer, Anders et al.

Ingår i PLOS ONE, 2024

• DOI för A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils
• Ladda ner fulltext (pdf) av A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Blood-brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer’s disease

Rofo, Fadi; Metzendorf, Nicole; Saubi, Cristina; Suominen, Laura et al.

Ingår i Alzheimer's Research & Therapy, 2022

• DOI för Blood-brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer’s disease
• Ladda ner fulltext (pdf) av Blood-brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer’s disease

Updated transient gene expression (TGE) protocol and the development of a small-scale TGE protocol: evaluated by testing longevity molecules as potential protein expression enhancers

de la Rosa, Andrés; Petrovic, Alex; Godec, Ana; Napoleone, Antonino et al.