Michael Landreh

Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Ingår i Journal of Biological Chemistry, 2026

• DOI för Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
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Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Ingår i Communications Materials, 2026

• DOI för Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
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Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Ingår i Communications Materials, 2026

• DOI för Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
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Unravelling the hidden complexities of R-phycoerythrins with a 3D-analytical chemistry approach

Niroda, Andres; Tuvikene, Rando; Landreh, Michael; Saluri, Mihkel

Ingår i Algal Research, 2026

• DOI för Unravelling the hidden complexities of R-phycoerythrins with a 3D-analytical chemistry approach

Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Ingår i Journal of the American Chemical Society, s. 23504-23518, 2025

• DOI för Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
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Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Ingår i Journal of Biological Chemistry, 2026

• DOI för Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
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Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Ingår i Communications Materials, 2026

• DOI för Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
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Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Ingår i Communications Materials, 2026

• DOI för Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
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Unravelling the hidden complexities of R-phycoerythrins with a 3D-analytical chemistry approach

Niroda, Andres; Tuvikene, Rando; Landreh, Michael; Saluri, Mihkel

Ingår i Algal Research, 2026

• DOI för Unravelling the hidden complexities of R-phycoerythrins with a 3D-analytical chemistry approach

Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Ingår i Journal of the American Chemical Society, s. 23504-23518, 2025

• DOI för Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
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Engineered Peptide Coacervates Enable Efficient Intracellular Delivery of the MYC Inhibitor omoMYC

Cerrato, Carmine P.; Krkoska, Martin; Sun, Yue; Liaño-Pons, Judit et al.

Ingår i Molecular Pharmaceutics, s. 3479-3490, 2025

• DOI för Engineered Peptide Coacervates Enable Efficient Intracellular Delivery of the MYC Inhibitor omoMYC
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Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor

Jin, Zhen; Pallisgaard Olsen, William; Mörman, Cecilia; Leppert, Axel et al.

Ingår i Science Advances, 2025

• DOI för Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor
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Stabilization of Protein Interactions through Electrospray Additives in Negative Ion Mode Native Mass Spectrometry

Stevens, Alexander; Abramsson, Mia L.; Agasid, Mark T.; Allison, Timothy M. et al.

Ingår i Analytical Chemistry, s. 10738-10744, 2025

• DOI för Stabilization of Protein Interactions through Electrospray Additives in Negative Ion Mode Native Mass Spectrometry
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Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

Abramsson, Mia L.; Corey, Robin A.; Skerle, Jan L.; Persson, Louise et al.

Ingår i eLIFE, 2025

• DOI för Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Ingår i JACS Au, s. 281-290, 2025

• DOI för Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
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High-Performance Molecular Dynamics Simulations for Native Mass Spectrometry of Large Protein Complexes with the Fast Multipole Method

Persson, Louise; Sahin, Cagla; Landreh, Michael; Marklund, Erik

Ingår i Analytical Chemistry, s. 15023-15030, 2024

• DOI för High-Performance Molecular Dynamics Simulations for Native Mass Spectrometry of Large Protein Complexes with the Fast Multipole Method
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A druggable conformational switch in the c-MYC transactivation domain

Lama, Dilraj; Vosselman, Thibault; Sahin, Cagla; Liaño-Pons, Judit et al.

Ingår i Nature Communications, 2024

• DOI för A druggable conformational switch in the c-MYC transactivation domain
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ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat

Nishio, Shunsuke; Emori, Chihiro; Wiseman, Benjamin; Fahrenkamp, Dirk et al.

Ingår i Cell, s. 1440-1.459e+27, 2024

• DOI för ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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Charging of DNA Complexes in Positive-Mode Native Electrospray Ionization Mass Spectrometry

Abramsson, Mia L.; Persson, Louise J.; Sobott, Frank; Marklund, Erik et al.

Ingår i Journal of the American Society for Mass Spectrometry, s. 3157-3162, 2024

• DOI för Charging of DNA Complexes in Positive-Mode Native Electrospray Ionization Mass Spectrometry
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AlphaFold with conformational sampling reveals the structural landscape of homorepeats

Bonet, Authors David Fernandez; Ranyai, Shahrayar; Aswad, Luay; Lane, David P. et al.

Ingår i Structure, s. 2160-2167, 2024

• DOI för AlphaFold with conformational sampling reveals the structural landscape of homorepeats
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Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions

Leppert, Axel; Feng, Jianhui; Railaite, Vaida; Pessatti, Tomas Bohn et al.

Ingår i Journal of the American Chemical Society, s. 19555-19565, 2024

• DOI för Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
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Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain

Leppert, Axel; Chen, Gefei; Lama, Dilraj; Sahin, Cagla et al.

Ingår i Nano Letters, s. 5836-5841, 2023

• DOI för Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain
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The heat shock protein LarA activates the Lon protease in response to proteotoxic stress

Omnus, Deike J.; Fink, Matthias J.; Kallazhi, Aswathy; Xandri Zaragoza, Maria et al.

Ingår i Nature Communications, 2023

• DOI för The heat shock protein LarA activates the Lon protease in response to proteotoxic stress
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Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures

Sahin, Cagla; Motso, Aikaterini; Gu, Xinyu; Feyrer, Hannes et al.

Ingår i Journal of the American Chemical Society, s. 10659-10668, 2023

• DOI för Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures
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Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry

Cerrato, Carmine P. P.; Leppert, Axel; Sun, Yue; Lane, David P. P. et al.

Ingår i Analytical Chemistry, s. 10869-10872, 2023

• DOI för Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry
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Advances in mass spectrometry to unravel the structure and function of protein condensates

Sahin, Cagla; Leppert, Axel; Landreh, Michael

Ingår i Nature Protocols, s. 3653-3661, 2023

• DOI för Advances in mass spectrometry to unravel the structure and function of protein condensates

Conformational modulation of intrinsically disordered transactivation domains for cancer therapy

Vosselman, Thibault; Sahin, Cagla; Lane, David P.; Henriksson, Marie Arsenian et al.

Ingår i PNAS Nexus, 2025

• DOI för Conformational modulation of intrinsically disordered transactivation domains for cancer therapy
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Liquid-liquid crystalline phase separation of spider silk proteins

Landreh, Michael; Osterholz, Hannah; Chen, Gefei; Knight, Stefan D. et al.

Ingår i Communications Chemistry, 2024

• DOI för Liquid-liquid crystalline phase separation of spider silk proteins
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Moving Past One-Size-Fits-All: Making the Right Choices in Molecular Dynamics Simulations for Native Mass Spectrometry

Persson, Louise; Landreh, Michael; Marklund, Erik

Activation of Protein Complexes in the Gas Phase: Insights from Molecular Dynamics Simulations and Ion Mobility Experiments

Persson, Louise; Naseeb, Noor; De Schepper, Stijn; Sen, Navoneel et al.