Johan Gising

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

De Rosa, Maria; Lu, Lu; Zamaratski, Edouard; Szałaj, Natalia et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 897-911, 2017

• DOI för Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)
• Ladda ner fulltext (pdf) av Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 2603-2620, 2016

• DOI för Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Russo, Francesco; Gising, Johan; Åkerbladh, Linda; Roos, Annette K. et al.

Ingår i ChemistryOpen, s. 342-362, 2015

• DOI för Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents
• Ladda ner fulltext (pdf) av Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Belfrage, Anna Karin; Gising, Johan; Svensson, Fredrik; Åkerblom, Eva et al.

Ingår i European Journal of Organic Chemistry, s. 978-986, 2015

• DOI för Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Gising, Johan; Belfrage, Anna Karin; Alogheli, Hiba; Ehrenberg, Angelica et al.

Ingår i Journal of Medicinal Chemistry, s. 1790-1801, 2014

• DOI för Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

De Rosa, Maria; Gising, Johan; Odell, Luke R; Larhed, Mats

Ingår i Upsala Journal of Medical Sciences, s. 181-191, 2014

• DOI för Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Gising, Johan; Larhed, Mats; Odell, Luke R

Ingår i Microwaves in Drug Discovery and Development, s. 34-54, Future Medicine, 2014

• DOI för Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Nordqvist, Anneli; Nilsson, Mikael T.; Lagerlund, Olof; Muthas, Daniel et al.

Ingår i MedChemComm, s. 620-626, 2012

• DOI för Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Design and Synthesis of Enzyme Inhibitors Against Infectious Diseases: Targeting Hepatitis C Virus NS3 Protease and Mycobacterium tuberculosis Ribonucleotide Reductase

Gising, Johan

2012

• Ladda ner fulltext (pdf) av Design and Synthesis of Enzyme Inhibitors Against Infectious Diseases: Targeting Hepatitis C Virus NS3 Protease and Mycobacterium tuberculosis Ribonucleotide Reductase

Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Sävmarker, Jonas; Rydfjord, Jonas; Gising, Johan; Odell, Luke R. et al.

Ingår i Organic Letters, s. 2394-2397, 2012

• DOI för Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Gising, Johan; Odell, Luke R.; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2713-2729, 2012

• DOI för Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Gising, Johan; Nilsson, Mikael T; Odell, Luke R; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 2894-2898, 2012

• DOI för Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors
• Ladda ner fulltext (pdf) av Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011

• DOI för Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

Örtqvist, Pernilla; Gising, Johan; Ehrenberg, Angelica; Vema, Aparna et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 6512-6525, 2010

• DOI för Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Gising, Johan; Örtqvist, Pernilla; Sandström, Anja; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2809-2815, 2009

• DOI för A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Odell, Luke R.; Nilsson, Mikael T.; Gising, Johan; Lagerlund, Olof et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 4790-4793, 2009

• DOI för Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Ekegren, Jenny; Gising, Johan; Wallberg, Hans; Larhed, Mats et al.

Ingår i Organic and biomolecular chemistry, s. 3040-3043, 2006

• DOI för Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold

Patel, Jayendra Z.; Sandberg, Lars; Wannberg, Johan; Söderström, Marcus et al.

Ingår i Results in Chemistry, 2026

• DOI för From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold
• Ladda ner fulltext (pdf) av From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold

New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold

Gising, Johan; Wannberg, Johan; Isaksson, Rebecka; Sallander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2026

• DOI för New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold
• Ladda ner fulltext (pdf) av New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold

Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B

Bhattacharya, Sayantani; Galkin, Maxim; Åhlén, Michelle; Strømme, Maria et al.

Ingår i ChemSusChem, 2026

• DOI för Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B
• Ladda ner fulltext (pdf) av Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B

Utilization of Polymers for Extracting Rare Earth Elements

Ding, Zixuan; Gising, Johan; Majka, Jarosław; Strömme, Maria et al.

Ingår i SERC 2026, 2026

The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats

Stam, Frida; Lind, Sara Florén; Zelleroth, Sofia; Badrd'din, Sally et al.

Ingår i IBRO Neuroscience Reports, s. 854-861, 2025

• DOI för The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats
• Ladda ner fulltext (pdf) av The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats

From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold

Patel, Jayendra Z.; Sandberg, Lars; Wannberg, Johan; Söderström, Marcus et al.

Ingår i Results in Chemistry, 2026

• DOI för From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold
• Ladda ner fulltext (pdf) av From virtual screening to selective angiotensin II type 2 receptor ligands: discovery of a novel scaffold

New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold

Gising, Johan; Wannberg, Johan; Isaksson, Rebecka; Sallander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2026

• DOI för New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold
• Ladda ner fulltext (pdf) av New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold

Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B

Bhattacharya, Sayantani; Galkin, Maxim; Åhlén, Michelle; Strømme, Maria et al.

Ingår i ChemSusChem, 2026

• DOI för Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B
• Ladda ner fulltext (pdf) av Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B

The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats

Stam, Frida; Lind, Sara Florén; Zelleroth, Sofia; Badrd'din, Sally et al.

Ingår i IBRO Neuroscience Reports, s. 854-861, 2025

• DOI för The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats
• Ladda ner fulltext (pdf) av The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats

Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran Håkansson, Esther et al.

Ingår i Neuroscience Letters, 2025

• DOI för Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures
• Ladda ner fulltext (pdf) av Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures

Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations

Beveridge, Julia; Söderström, Marcus; Balestri, Lorenzo; Prieto-Díaz, Rubén et al.

Ingår i Synlett, s. 2666-2670, 2025

• DOI för Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations
• Ladda ner fulltext (pdf) av Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations

From Phenolated Lignin to Few-Layered Graphene: Laser-Induced Carbonization for Micro-Supercapacitor Application

Iurchenkova, Anna A.; Frasca, Serena; Åhlén, Michelle; Zhu, Yuan et al.

Ingår i ACS Sustainable Chemistry and Engineering, s. 14961-14970, 2025

• DOI för From Phenolated Lignin to Few-Layered Graphene: Laser-Induced Carbonization for Micro-Supercapacitor Application
• Ladda ner fulltext (pdf) av From Phenolated Lignin to Few-Layered Graphene: Laser-Induced Carbonization for Micro-Supercapacitor Application

From Phenolated Lignin to Few-Layered Graphene: Laser-Induced Carbonization for Micro-Supercapacitor Application

Iurchenkova, Anna A.; Frasca, Serena; Åhlén, Michelle; Zhu, Yuan et al.

Ingår i ACS Sustainable Chemistry & Engineering, 2025

• DOI för From Phenolated Lignin to Few-Layered Graphene: Laser-Induced Carbonization for Micro-Supercapacitor Application

A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary

Lindman, Jens; Puthiyaparambath, Sharathna; Gising, Johan; Odell, Luke R. et al.

Ingår i Synlett, s. 2009-2013, 2025

• DOI för A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary
• Ladda ner fulltext (pdf) av A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Ladda ner fulltext (pdf) av N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Compatibility of Kraft Lignin and Phenol-Organosolv Lignin with PLA in 3D Printing and Assessment of Mechanical Recycling

Frasca, Serena; Katsiotis, Christos S.; Henrik-Klemens, Åke; Larsson, Anette et al.

Ingår i ACS Applied Polymer Materials, s. 13574-13584, 2024

• DOI för Compatibility of Kraft Lignin and Phenol-Organosolv Lignin with PLA in 3D Printing and Assessment of Mechanical Recycling
• Ladda ner fulltext (pdf) av Compatibility of Kraft Lignin and Phenol-Organosolv Lignin with PLA in 3D Printing and Assessment of Mechanical Recycling

Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran, Esther et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
• Ladda ner fulltext (pdf) av Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Synthesis of N-Alkenylated Heterocycles via T₃P-Promoted Condensation with Ketones

Balestri, Lorenzo Jacopo Ilic; Beveridge, Julia; Gising, Johan; Odell, Luke R.

Ingår i Journal of Organic Chemistry, s. 11203-11214, 2024

• DOI för Synthesis of N-Alkenylated Heterocycles via T₃P-Promoted Condensation with Ketones
• Ladda ner fulltext (pdf) av Synthesis of N-Alkenylated Heterocycles via T₃P-Promoted Condensation with Ketones

Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Ingår i European Journal of Medicinal Chemistry Reports, 2024

• DOI för Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
• Ladda ner fulltext (pdf) av Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Toward Biomass-Based Organic Electronics: Continuous Flow Synthesis and Electropolymerization of N-Substituted Pyrroles

Frasca, Serena; Galkin, Maxim; Strömme, Maria; Lindh, Jonas et al.

Ingår i ACS Omega, s. 13852-13859, 2024

• DOI för Toward Biomass-Based Organic Electronics: Continuous Flow Synthesis and Electropolymerization of N-Substituted Pyrroles
• Ladda ner fulltext (pdf) av Toward Biomass-Based Organic Electronics: Continuous Flow Synthesis and Electropolymerization of N-Substituted Pyrroles

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Gising, Johan; Honarnejad, Saman; Bras, Maaike; Baillie, Gemma L. et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
• Ladda ner fulltext (pdf) av The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Zelleroth, Sofia; Stam, Frida; Nylander, Erik; Ellinor, Kjellgren et al.

Ingår i Hormones and Behavior, 2024

• DOI för The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat
• Ladda ner fulltext (pdf) av The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Engen, Karin; Lundbäck, Thomas; Yadav, Anubha; Puthiyaparambath, Sharathna et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation
• Ladda ner fulltext (pdf) av Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles

Lindman, Jens; Yadav, Anubha; Gising, Johan; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 12978-12985, 2023

• DOI för Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles
• Ladda ner fulltext (pdf) av Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles

Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Stam, Frida; Lind, Sara Florén; Schroff, Anja; Zelleroth, Sofia et al.

Ingår i Current Issues in Molecular Biology, s. 5000-5012, 2022

• DOI för Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures
• Ladda ner fulltext (pdf) av Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022

• DOI för 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands
• Ladda ner fulltext (pdf) av 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations

Lindman, Jens; Gopalan, Greeshma; Palo-Nieto, Carlos; Brandt, Peter et al.

Ingår i ACS Omega, 2022

• DOI för Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations
• Ladda ner fulltext (pdf) av Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations

ENABLE: an engine for European antibacterial drug discovery and development

Olliver, Marie; Griestop, Laura; Hughes, Diarmaid; Belfrage, Anna Karin et al.

Ingår i Nature reviews. Drug discovery, s. 407-408, 2021

• DOI för ENABLE: an engine for European antibacterial drug discovery and development

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2021

• DOI för N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Ingår i ChemistryOpen, s. 114-125, 2019

• DOI för A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
• Ladda ner fulltext (pdf) av A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

De Rosa, Maria; Lu, Lu; Zamaratski, Edouard; Szałaj, Natalia et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 897-911, 2017

• DOI för Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)
• Ladda ner fulltext (pdf) av Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 2603-2620, 2016

• DOI för Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Russo, Francesco; Gising, Johan; Åkerbladh, Linda; Roos, Annette K. et al.

Ingår i ChemistryOpen, s. 342-362, 2015

• DOI för Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents
• Ladda ner fulltext (pdf) av Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Belfrage, Anna Karin; Gising, Johan; Svensson, Fredrik; Åkerblom, Eva et al.

Ingår i European Journal of Organic Chemistry, s. 978-986, 2015

• DOI för Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Gising, Johan; Belfrage, Anna Karin; Alogheli, Hiba; Ehrenberg, Angelica et al.

Ingår i Journal of Medicinal Chemistry, s. 1790-1801, 2014

• DOI för Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Nordqvist, Anneli; Nilsson, Mikael T.; Lagerlund, Olof; Muthas, Daniel et al.

Ingår i MedChemComm, s. 620-626, 2012

• DOI för Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Sävmarker, Jonas; Rydfjord, Jonas; Gising, Johan; Odell, Luke R. et al.

Ingår i Organic Letters, s. 2394-2397, 2012

• DOI för Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Gising, Johan; Odell, Luke R.; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2713-2729, 2012

• DOI för Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Gising, Johan; Nilsson, Mikael T; Odell, Luke R; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 2894-2898, 2012

• DOI för Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors
• Ladda ner fulltext (pdf) av Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011

• DOI för Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Hepatitis C protease inhibitors based on 2(1H)-pyrazinones

Gising, Johan; Belfrage, Anna Karin; Örtqvist, Pernilla; Larhed, Mats et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2010

Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

Örtqvist, Pernilla; Gising, Johan; Ehrenberg, Angelica; Vema, Aparna et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 6512-6525, 2010

• DOI för Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Gising, Johan; Örtqvist, Pernilla; Sandström, Anja; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2809-2815, 2009

• DOI för A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Odell, Luke R.; Nilsson, Mikael T.; Gising, Johan; Lagerlund, Olof et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 4790-4793, 2009

• DOI för Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Ekegren, Jenny; Gising, Johan; Wallberg, Hans; Larhed, Mats et al.

Ingår i Organic and biomolecular chemistry, s. 3040-3043, 2006

• DOI för Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

De Rosa, Maria; Gising, Johan; Odell, Luke R; Larhed, Mats

Ingår i Upsala Journal of Medical Sciences, s. 181-191, 2014

• DOI för Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

Design and Synthesis of Enzyme Inhibitors Against Infectious Diseases: Targeting Hepatitis C Virus NS3 Protease and Mycobacterium tuberculosis Ribonucleotide Reductase

Gising, Johan

2012

• Ladda ner fulltext (pdf) av Design and Synthesis of Enzyme Inhibitors Against Infectious Diseases: Targeting Hepatitis C Virus NS3 Protease and Mycobacterium tuberculosis Ribonucleotide Reductase

Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Gising, Johan; Larhed, Mats; Odell, Luke R

Ingår i Microwaves in Drug Discovery and Development, s. 34-54, Future Medicine, 2014

• DOI för Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Utilization of Polymers for Extracting Rare Earth Elements

Ding, Zixuan; Gising, Johan; Majka, Jarosław; Strömme, Maria et al.

Ingår i SERC 2026, 2026

Stabilization strategies to tailor-made lignin for materials

Galkin, Maxim; Iurchenkova, Anna; Frasca, Serena; Bhattacharya, Sayantani et al.

2025

One process of biomass fractionation, endless possibilities for tailor-made solutions

Gising, Johan; Galkin, Maxim

Ingår i Nobel Forum Satellite event: Green Chemistry 2025, 2025

Active Lignin Stabilization Pulping for Electrochemical Energy Storage Materials

Galkin, Maxim; Iurchenkova, Anna A.; Fransca, Serena; Gising, Johan

Ingår i Nobel Forum Satellite Event: Green Chemistry 2025., 2025

Active Lignin Stabilization Pulping for Electrochemical Energy Storage Materials

Galkin, Maxim; Iurchenkova, Anna A.; Frasca, Serena; Gising, Johan

Ingår i Nobel Forum Satellite Event: Green Chemistry 2025, 2025

Hållbar materialutveckling med hjälp av avancerad teknologi öppnar möjligheter till helt nya innovationer

Strömme, Maria; Gising, Johan; Cheung, Ocean; Lindh, Jonas

Ingår i FOI-dagen: innovationer för ett effektivare och hållbart infrastrukturunderhåll 2024, 2024

Toward biomass-based organic electronics:: Continuous flow synthesis and electropolymerization of N-substituted pyrroles

Frasca, Serena; Galkin, Maxim; Strömme, Maria; Lindh, Jonas et al.

Ingår i RCS Poster Conference 2024, 2024

Toward biomass-based organic electronics: Continuous flow synthesis and electropolymerization of N-substituted polypyrroles

Frasca, Serena; Galkin, Maxim; Iurchenkova, Anna A.; Strömme, Maria et al.

Ingår i ACS Spring meeting 2023, 2023

Laser-Induced few-layers graphene formation from Phenolated lignin

Frasca, Serena; Iurchenkova, Anna A.; Åhlén, Michelle; Zhu, Yuan et al.

Tailoring Lignin Properties During Biomass Fractionation: Paving the way for functionalized bio-based materials.

Galkin, Maxim; Frasca, Serena; Strömme, Maria; Lindh, Jonas et al.

Free-standing carbon films produced via laser-induced carbonisation for application in Li-ion batteries.

Iurchenkova, Anna A.; Kobets, Anna; Galkin, Maxim; Sjödin, Martin et al.

Functionalized lignin, a method for preparation thereof as well as uses thereof

Gising, Johan; Galkin, Maxim

2024