Jakob Haglöf

Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Haglöf, Jakob; Nilsson, Jenny M.; Ludvigsson, Jufang Wu

Ingår i Journal of Separation Science, 2025

• DOI för Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
• Ladda ner fulltext (pdf) av Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

Haglöf, Jakob; Bivehed, Erik; Sänger-van de Griend, Cari

Ingår i Talanta, 2025

• DOI för Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
• Ladda ner fulltext (pdf) av Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob et al.

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, 2023

• DOI för DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
• Ladda ner fulltext (pdf) av DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

Steffen, Karin; Indraningrat, Anak Agung Gede; Erngren, Ida; Haglöf, Jakob et al.

Ingår i Scientific Reports, 2022

• DOI för Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
• Ladda ner fulltext (pdf) av Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Nylund, Patrick; Atienza Párraga, Alba; Haglöf, Jakob; De Bruyne, Elke et al.

Ingår i Cell Death and Disease, 2021

• DOI för A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
• Ladda ner fulltext (pdf) av A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Haglöf, Jakob; Nilsson, Jenny M.; Ludvigsson, Jufang Wu

Ingår i Journal of Separation Science, 2025

• DOI för Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
• Ladda ner fulltext (pdf) av Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

Haglöf, Jakob; Bivehed, Erik; Sänger-van de Griend, Cari

Ingår i Talanta, 2025

• DOI för Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
• Ladda ner fulltext (pdf) av Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob et al.

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, 2023

• DOI för DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
• Ladda ner fulltext (pdf) av DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

Steffen, Karin; Indraningrat, Anak Agung Gede; Erngren, Ida; Haglöf, Jakob et al.

Ingår i Scientific Reports, 2022

• DOI för Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
• Ladda ner fulltext (pdf) av Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges

A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Nylund, Patrick; Atienza Párraga, Alba; Haglöf, Jakob; De Bruyne, Elke et al.

Ingår i Cell Death and Disease, 2021

• DOI för A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
• Ladda ner fulltext (pdf) av A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

Lindell Jonsson, Eva; Erngren, Ida; Engskog, Mikael; Haglöf, Jakob et al.

Ingår i Frontiers in Oncology, 2019

• DOI för Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
• Ladda ner fulltext (pdf) av Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

Pirttilä, Kristian; Pierre, Pernilla Videhult; Haglöf, Jakob; Engskog, Mikael et al.

Ingår i Metabolomics, 2019

• DOI för An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs
• Ladda ner fulltext (pdf) av An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Erngren, Ida; Haglöf, Jakob; Engskog, Mikael K R; Nestor, Marika et al.

Ingår i Journal of Chromatography A, s. 174-182, 2019

• DOI för Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K R; Erngren, Ida et al.

Ingår i Journal of Chromatography A, s. 49-56, 2018

• DOI för Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Häggblad Sahlberg, Sara; Mortensen, Anja C.; Haglöf, Jakob; Engskog, Mikael K. R. et al.

Ingår i International Journal of Oncology, s. 5-14, 2017

• DOI för Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells
• Ladda ner fulltext (pdf) av Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling

Engskog, Mikael K. R.; Ersson, Lisa; Haglöf, Jakob; Arvidsson, Torbjörn et al.

Ingår i Amino Acids, s. 905-919, 2017

• DOI för β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
• Ladda ner fulltext (pdf) av β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling

Cisplatin-induced metabolome changes in serum: an experimental approach to identify markers for ototoxicity

Pierre, Pernilla Videhult; Haglöf, Jakob; Linder, Birgitta; Engskog, Mikael K R et al.

Ingår i Acta Oto-Laryngologica, s. 1024-1030, 2017

• DOI för Cisplatin-induced metabolome changes in serum: an experimental approach to identify markers for ototoxicity

The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K. R.; Nestor, Marika et al.

Ingår i Analytica Chimica Acta, s. 40-47, 2017

• DOI för The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

TAp73 is a marker of glutamine addiction in medulloblastoma

Niklison-Chirou, Maria Victoria; Erngren, Ida; Engskog, Mikael K R; Haglöf, Jakob et al.

Ingår i Genes & Development, s. 1738-1753, 2017

• DOI för TAp73 is a marker of glutamine addiction in medulloblastoma
• Ladda ner fulltext (pdf) av TAp73 is a marker of glutamine addiction in medulloblastoma

NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.

Elmsjö, Albert; Rosqvist, Fredrik; Engskog, Mikael K R; Haglöf, Jakob et al.

Ingår i Nutrition & Diabetes, 2015

• DOI för NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
• Ladda ner fulltext (pdf) av NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.

Metabolic profiling of epithelial ovarian cancer cell lines: evaluation of harvesting protocols for profiling using NMR spectroscopy

Engskog, Mikael K R; Björklund, My; Haglöf, Jakob; Arvidsson, Torbjörn et al.

Ingår i Bioanalysis, s. 157-166, 2015

• DOI för Metabolic profiling of epithelial ovarian cancer cell lines: evaluation of harvesting protocols for profiling using NMR spectroscopy

Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation

Colombo, Stefano; Brisander, Magnus; Haglöf, Jakob; Sjövall, Peter et al.

Ingår i International Journal of Pharmaceutics, s. 205-217, 2015

• DOI för Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation

NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

Aftab, Obaid; Engskog, Mikael; Haglöf, Jakob; Elmsjö, Albert et al.

Ingår i Journal of chemical information and modeling, s. 3251-3258, 2014

• DOI för NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

The cyanobacterial amino acid beta-N-methylamino-L-alanine perturbs the intermediary metabolism in neonatal rats

Engskog, Mikael K R; Karlsson, Oskar; Haglöf, Jakob; Elmsjö, Albert et al.

Ingår i Amino Acids, s. 905-919, 2013

• DOI för The cyanobacterial amino acid beta-N-methylamino-L-alanine perturbs the intermediary metabolism in neonatal rats

Separation of amino alcohols using divalent dipeptides as counter ions in aqueous CE

Haglöf, Jakob; Pettersson, Curt

Ingår i Electrophoresis, s. 1706-1712, 2010

• DOI för Separation of amino alcohols using divalent dipeptides as counter ions in aqueous CE

Effect of alkali metal hydroxides on the enantioseparation of amines using di-O-isopropylidene-keto-L-gulonic acid as the selector in NACE

Hedeland, Ylva; Haglöf, Jakob; Beronius, Per; Pettersson, Curt

Ingår i Electrophoresis, s. 4469-4479, 2006

• DOI för Effect of alkali metal hydroxides on the enantioseparation of amines using di-O-isopropylidene-keto-L-gulonic acid as the selector in NACE

LC-MS based global metabolite profiling: the necessity of high data quality

Engskog, Mikael K. R.; Haglöf, Jakob; Arvidsson, Torbjörn; Pettersson, Curt

Ingår i Metabolomics, 2016

• DOI för LC-MS based global metabolite profiling: the necessity of high data quality

Enantiomeric Separations using Chiral Counter-Ions

Haglöf, Jakob

2010

• Ladda ner fulltext (pdf) av Enantiomeric Separations using Chiral Counter-Ions

Evaluation of harvesting protocols for metabolic profiling of epithelial ovarian cancer cells

Engskog, Mikael K R; Haglöf, Jakob; Arvidsson, Torbjörn; Pettersson, Curt

2014

• Ladda ner fulltext (pdf) av Evaluation of harvesting protocols for metabolic profiling of epithelial ovarian cancer cells

Ototoxicity of Cisplatin Correlates with Changes in Blood Antioxidant Status

Videhult Pierre, Pernilla; Haglöf, Jakob; Linder, Birgitta; Engskog, Mikael K R et al.

2014

Multivariate analysis of enantiomeric separation of amino alcohols using N-derivatized dipeptides as chiral selectors in HPLC

Haglöf, Jakob; Karlsson, Anders

2010

Capillary electrophoretic studies of ion pairing in aqueous solution using N-derivatized dipeptides

Haglöf, Jakob; Pettersson, Curt

2008

Enantiomeric separation of amines using divalent N-derivatized dipeptides as chiral selectors in non-aqueous capillary electrophoresis

Haglöf, Jakob; Pettersson, Curt

2008

Enantiomeric separation of amines using divalent dipeptides as chiral counter-ions in non-aqueous CE

Haglöf, Jakob; Pettersson, Curt

Multivariate data analysis of a chiral separation system using N-derivatized dipeptides as chiral counter-ions on porous graphitic carbon stationary phase

Haglöf, Jakob; Karlsson, Anders

Optimization of In Vitro Microsome Incubations for Improved Drug Metabolite Yield Utilizing Experimental Design

Nilsson Broberg, Malin; Haglöf, Jakob; Bondesson, Ulf; Pettersson, Curt et al.