Dag Leonard

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Hedenstedt, Anna; Reid, Sarah; Sayadi, Ahmed; Eloranta, Maija-Leena et al.

Ingår i Lupus Science and Medicine, 2023

• DOI för B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Reid, Sarah; Hagberg, Niklas; Sandling, Johanna K.; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1183-1189, 2021

• DOI för Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Ingår i Annals of the Rheumatic Diseases, s. 363-369, 2020

• DOI för High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Interferon pathway in SLE: one key to unlocking the mystery of the disease

Rönnblom, Lars; Leonard, Dag

Ingår i Lupus Science and Medicine, 2019

• DOI för Interferon pathway in SLE: one key to unlocking the mystery of the disease
• Ladda ner fulltext (pdf) av Interferon pathway in SLE: one key to unlocking the mystery of the disease

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1063-1069, 2018

• DOI för Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
• Ladda ner fulltext (pdf) av Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 1728-1734, 2016

• DOI för Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Epidemiology of patients with moderate-to-severe SLE in Sweden

Frodlund, Martina; Leonard, Dag; Haugli-Stephens, Thomas; Remkus, Lauren et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Epidemiology of patients with moderate-to-severe SLE in Sweden
• Ladda ner fulltext (pdf) av Epidemiology of patients with moderate-to-severe SLE in Sweden

A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Fugmann, Cecilia; Reid, Sarah; Pucholt, Pascal; Kvarnström, Marika et al.

Ingår i Rheumatology, s. 4341-4346, 2025

• DOI för A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease
• Ladda ner fulltext (pdf) av A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Badrising, U. A.; Henderson, R.; Reddel, S.; Corbett, A. et al.

Ingår i Clinical and Experimental Rheumatology, s. 316-325, 2025

• DOI för Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, s. 212-225, 2025

• DOI för Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Stockfelt, Marit; Torell, Agnes; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Rheumatology, s. 1469-1475, 2024

• DOI för Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Epidemiology of patients with moderate-to-severe SLE in Sweden

Frodlund, Martina; Leonard, Dag; Haugli-Stephens, Thomas; Remkus, Lauren et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Epidemiology of patients with moderate-to-severe SLE in Sweden
• Ladda ner fulltext (pdf) av Epidemiology of patients with moderate-to-severe SLE in Sweden

A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Fugmann, Cecilia; Reid, Sarah; Pucholt, Pascal; Kvarnström, Marika et al.

Ingår i Rheumatology, s. 4341-4346, 2025

• DOI för A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease
• Ladda ner fulltext (pdf) av A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Badrising, U. A.; Henderson, R.; Reddel, S.; Corbett, A. et al.

Ingår i Clinical and Experimental Rheumatology, s. 316-325, 2025

• DOI för Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, s. 212-225, 2025

• DOI för Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Stockfelt, Marit; Torell, Agnes; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Rheumatology, s. 1469-1475, 2024

• DOI för Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study

Frodlund, Martina; Jonsen, Andreas; Remkus, Lauren; Telg, Gunilla et al.

Ingår i Rheumatology, s. 1104-1112, 2024

• DOI för Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study
• Ladda ner fulltext (pdf) av Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study

Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Torell, Agnes; Stockfelt, Marit; Blennow, Kaj; Zetterberg, Henrik et al.

Ingår i Arthritis Research & Therapy, 2024

• DOI för Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy
• Ladda ner fulltext (pdf) av Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study

Lodin, Karin; Espinosa-Ortega, Fabricio; Dastmalchi, Maryam; Vencovsky, Jiri et al.

Ingår i Seminars in Arthritis & Rheumatism, 2024

• DOI för Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study
• Ladda ner fulltext (pdf) av Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study

A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Ingår i Journal of Autoimmunity, 2024

• DOI för A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
• Ladda ner fulltext (pdf) av A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Hedenstedt, Anna; Reid, Sarah; Sayadi, Ahmed; Eloranta, Maija-Leena et al.

Ingår i Lupus Science and Medicine, 2023

• DOI för B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

Torell, Agnes; Stockfelt, Marit; Larsson, Gunilla; Blennow, Kaj et al.

Ingår i Arthritis Research & Therapy, 2023

• DOI för Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022

• DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Yavuz, Sule; Pucholt, Pascal; Sandling, Johanna K.; Bianchi, Matteo et al.

Ingår i Lupus Science and Medicine, 2022

• DOI för Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
• Ladda ner fulltext (pdf) av Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Diaz-Gallo, Lina-Marcela; Oke, Vilija; Lundström, Emeli; Elvin, Kerstin et al.

Ingår i ACR Open Rheumatology, s. 27-39, 2022

• DOI för Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations
• Ladda ner fulltext (pdf) av Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Lundtoft, Christian; Sjöwall, Christopher; Rantapää‐Dahlqvist, Solbritt; Bengtsson, Anders A. et al.

Ingår i Arthritis & Rheumatology, s. 1842-1850, 2022

• DOI för Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
• Ladda ner fulltext (pdf) av Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Quick Systemic Lupus Activity Questionnaire (Q-SLAQ): a simplified version of SLAQ for patient-reported disease activity

Svenungsson, Elisabet; Gunnarsson, Iva; Illescas-Backelin, Vera; Trysberg, Estelle et al.

Ingår i Lupus Science and Medicine, 2021

• DOI för Quick Systemic Lupus Activity Questionnaire (Q-SLAQ): a simplified version of SLAQ for patient-reported disease activity
• Ladda ner fulltext (pdf) av Quick Systemic Lupus Activity Questionnaire (Q-SLAQ): a simplified version of SLAQ for patient-reported disease activity

Variants in BANK1 are associated with lupus nephritis of European ancestry.

Bolin, Karin; Imgenberg-Kreuz, Juliana; Leonard, Dag; Sandling, Johanna K. et al.

Ingår i Genes and Immunity, s. 194-202, 2021

• DOI för Variants in BANK1 are associated with lupus nephritis of European ancestry.
• Ladda ner fulltext (pdf) av Variants in BANK1 are associated with lupus nephritis of European ancestry.

De novo lupus nephritis during treatment with belimumab

Parodis, Ioannis; Vital, Edward M.; Hassan, Sabih-Ul; Jönsen, Andreas et al.

Ingår i Rheumatology, s. 4348-4354, 2021

• DOI för De novo lupus nephritis during treatment with belimumab
• Ladda ner fulltext (pdf) av De novo lupus nephritis during treatment with belimumab

Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

Walhelm, Tomas; Gunnarsson, Iva; Heijke, Rebecca; Leonard, Dag et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study
• Ladda ner fulltext (pdf) av Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Reid, Sarah; Hagberg, Niklas; Sandling, Johanna K.; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1183-1189, 2021

• DOI för Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis

Yavuz, Sule; Bianchi, Matteo; Kozyrev, Sergey; Bolin, Karin et al.

Ingår i Annals of the Rheumatic Diseases, s. 404-406, 2021

• DOI för Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis
• Ladda ner fulltext (pdf) av Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis

Contributions of de novo variants to systemic lupus erythematosus

Carlsson Almlöf, Jonas; Nystedt, Sara; Mechtidou, Aikaterini; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 184-193, 2021

• DOI för Contributions of de novo variants to systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Contributions of de novo variants to systemic lupus erythematosus

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Sandling, Johanna K.; Pucholt, Pascal; Hultin-Rosenberg, Lina; Farias, Fabiana H. G. et al.

Ingår i Annals of the Rheumatic Diseases, s. 109-117, 2021

• DOI för Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
• Ladda ner fulltext (pdf) av Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Enocsson, Helena; Gullstrand, Birgitta; Eloranta, Maija-Leena; Wetterö, Jonas et al.

Ingår i Frontiers in Immunology, 2021

• DOI för C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
• Ladda ner fulltext (pdf) av C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Ingår i Annals of the Rheumatic Diseases, s. 363-369, 2020

• DOI för High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Linge, Petrus; Arve, Sabine; Olsson, Lina M.; Leonard, Dag et al.

Ingår i Annals of the Rheumatic Diseases, s. 254-261, 2020

• DOI för NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

Yavuz, Sule; Cansu, Dondu U.; Nikolopoulos, Dionysis; Crisafulli, Francesca et al.

Ingår i Seminars in Arthritis & Rheumatism, s. 1387-1393, 2020

• DOI för Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

Sex differences in clinical presentation of systemic lupus erythematosus

Ramírez Sepúlveda, Jorge I; Bolin, Karin; Mofors, Johannes; Leonard, Dag et al.

Ingår i Biology of Sex Differences, 2019

• DOI för Sex differences in clinical presentation of systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Sex differences in clinical presentation of systemic lupus erythematosus

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, Lina; Jevnikar, Zala; Riise, Rebecca; Oberg, Lisa et al.

Ingår i Annals of the Rheumatic Diseases, s. 1363-1370, 2019

• DOI för Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness

Segerberg, Filip; Lundtoft, Christian; Reid, Sarah; Hjorton, Karin et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness
• Ladda ner fulltext (pdf) av Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness

The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts

Frodlund, M.; Reid, Sarah; Wettero, J.; Dahlstrom, O. et al.

Ingår i Lupus, s. 1261-1272, 2019

• DOI för The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts
• Ladda ner fulltext (pdf) av The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts

Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas; Leonard, Dag; Sjöwall, Christopher et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome
• Ladda ner fulltext (pdf) av Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome

Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

Almlöf, Jonas Carlsson; Nystedt, Sara; Leonard, Dag; Eloranta, Maija-Leena et al.

Ingår i Human Genetics, s. 141-150, 2019

• DOI för Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Farias, Fabiana H. G.; Dahlqvist, Johanna; Kozyrev, Sergey V.; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 432-441, 2019

• DOI för A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
• Ladda ner fulltext (pdf) av A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Shared and unique patterns of DNA methylation in primary Sjogren's syndrome and systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Leonard, Dag; Carlsson Almlöf, Jonas; Rantapaa-Dahlqvist, S. et al.

Ingår i Scandinavian Journal of Rheumatology, s. 3-3, 2018

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1063-1069, 2018

• DOI för Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
• Ladda ner fulltext (pdf) av Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 736-743, 2018

• DOI för DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

Hagberg, Niklas; Joelsson, Martin; Leonard, Dag; Reid, Sarah et al.

Ingår i Annals of the Rheumatic Diseases, s. 1070-1077, 2018

• DOI för The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
• Ladda ner fulltext (pdf) av The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

The risk allele A of rs200395694 associated with SLE in Swedish patients affects on MEF2D gene regulation and alternative splicing

Abramov, Sergei; Kozyrev, Sergey V.; Farias, Fabiana H. G.; Dahlqvist, Johanna et al.

Ingår i Human Gene Therapy, 2018

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Bremer, Hanna D.; Landegren, Nils; Sjöberg, Ronald; Hallgren, Åsa et al.

Ingår i Scientific Reports, 2018

• DOI för ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
• Ladda ner fulltext (pdf) av ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Carlsson Almlöf, Jonas; Alexsson, Andrei; Imgenberg-Kreuz, Juliana; Sylwan, Lina et al.

Ingår i Scientific Reports, 2017

• DOI för Novel risk genes for systemic lupus erythematosus predicted by random forest classification
• Ladda ner fulltext (pdf) av Novel risk genes for systemic lupus erythematosus predicted by random forest classification

High Genetic Risk Score Is Associated with Increased Organ Damage in SLE

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, 2017

Treatment-Associated DNA Methylation Patterns in Systemic Lupus Erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Nordmark, Gunnel et al.

Ingår i Arthritis & Rheumatology, 2017

SLE Comprises Four Immune-Phenotypes, Which Differ Regarding HLA-DRB1 and Clinical Associations

Gallo, Lina Marcela Diaz; Lundstrom, Emeli; Oke, Vilija; Elvin, Kerstin et al.

Ingår i Arthritis & Rheumatology, 2017

A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Olsson, Lina M.; Johansson, Asa C.; Gullstrand, Birgitta; Jonsen, Andreas et al.

Ingår i Annals of the Rheumatic Diseases, s. 1607-1613, 2017

• DOI för A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 1728-1734, 2016

• DOI för Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Early B Cell Factor 1 is Associated to Clinical Manifestations in Primary Sjogren's Syndrome and SLE

Bolin, Karin; Leonard, Dag; Gunnarsson, I.; Sjowall, C. et al.

Ingår i Scandinavian Journal of Immunology, s. 416-416, 2015

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Scandinavian Journal of Rheumatology, s. 88-89, 2014

High-Throughput Sequencing of 219 Candidate Genes for Identification of SLE-Associated Risk Variants

Farias, Fabiana; Wilbe, Maria; Dahlqvist, Johanna; Leonard, Dag et al.

Ingår i Arthritis & Rheumatology, 2014

Activated SLE-T Cells Enhance the Interferon-Alpha Production By Plasmacytoid Dendritic Cells Stimulated By RNA-IC

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Arthritis & Rheumatology, 2014

Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

Vikerfors, Anna; Johansson, Anna-Britta; Gustafsson, Johanna T; Jönsen, Andreas et al.

Ingår i Rheumatology, s. 345-353, 2013

• DOI för Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Lundström, Emeli; Gustafsson, Johanna T; Jönsen, Andreas; Leonard, Dag et al.

Ingår i Annals of the Rheumatic Diseases, s. 1018-1025, 2013

• DOI för HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Leonard, Dag; Svenungsson, Elisabet; Sandling, Johanna K; Berggren, Olof et al.

Ingår i Circulation, s. 255-263, 2013

• DOI för Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Direct and Indirect Costs For Patients With Systemic Lupus Erythematosus In National Cohorts In Sweden

Jonsen, Andreas; Bengtsson, Anders A.; Bengtsson, Christine; Gunnarsson, Iva et al.

Ingår i Arthritis and Rheumatism, 2013

Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Leonard, Dag; Svenungsson, E.; Sandling, J. K.; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 270-270, 2013

• DOI för Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Ischemic vascular disease and antiphospholipid antibodies are associated with HLA-DRB1 *04/*13 alleles in systemic lupus erythematosus

Svenungsson, Elisabet; Lundström, Emeli; Gustafsson, Johanna; Jonsen, Andreas et al.

Ingår i Annals of the Rheumatic Diseases, 2012

• DOI för Ischemic vascular disease and antiphospholipid antibodies are associated with HLA-DRB1 *04/*13 alleles in systemic lupus erythematosus

Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

Leonard, Dag; Akhter, Tansim; Nordmark, Gunnel; Rönnblom, Lars et al.

Ingår i Scandinavian Journal of Rheumatology, s. 279-282, 2011

• DOI för Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Hagberg, Niklas; Berggren, Olof; Leonard, Dag; Weber, Gert et al.

Ingår i Journal of Immunology, s. 5085-5094, 2011

• DOI för IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna; Leonard, Dag; Sandling, Johanna et al.

Ingår i Annals of the Rheumatic Diseases, s. 834-840, 2010

• DOI för A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

Interferon pathway in SLE: one key to unlocking the mystery of the disease

Rönnblom, Lars; Leonard, Dag

Ingår i Lupus Science and Medicine, 2019

• DOI för Interferon pathway in SLE: one key to unlocking the mystery of the disease
• Ladda ner fulltext (pdf) av Interferon pathway in SLE: one key to unlocking the mystery of the disease

Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Jönsen, Andreas; Hjalte, Frida; Willim, Minna; Carlsson, Katarina Steen et al.

Ingår i Seminars in Arthritis & Rheumatism, s. 684-690, 2016

• DOI för Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Cardiovascular Disease and Immune Mechanisms in Systemic Lupus Erythematosus

Leonard, Dag

2014

• Ladda ner fulltext (pdf) av Cardiovascular Disease and Immune Mechanisms in Systemic Lupus Erythematosus

Variants in BANK1 are associated with lupus nephritis

Bolin, Karin; Leonard, Dag; Sandling, Johanna K.; Imgenberg-Kreuz, Juliana et al.

From genetic predisposition to clinical outcome in systemic lupus erythematosus: construction and validation of sub-phenotype-specific genetic risk scores

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.