Paul Skorup

Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock

Rundgren, Henrik; Sjoholm, Johan; Juric, Sanja; Janson, Pellina et al.

Ingår i Scientific Reports, 2025

• DOI för Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive Care Medicine Experimental, 2025

• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli

Bahnasawy, Salma M.; Skorup, Paul; Hanslin, Katja; Friberg, Lena et al.

Ingår i Cytokine, 2023

• DOI för Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli
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Qdenga®- A promising dengue fever vaccine; can it be recommended to non-immune travelers?

Angelin, Martin; Sjölin, Jan; Kahn, Fredrik; Ljunghill Hedberg, Anna et al.

Ingår i Travel Medicine and Infectious Disease, 2023

• DOI för Qdenga®- A promising dengue fever vaccine; can it be recommended to non-immune travelers?
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Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury

Luther, Tomas; Bülow-Anderberg, Sara; Persson, Patrik; Franzén, Stephanie et al.

Ingår i American Journal of Physiology - Renal Physiology, s. 571-580, 2023

• DOI för Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury
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Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock

Rundgren, Henrik; Sjoholm, Johan; Juric, Sanja; Janson, Pellina et al.

Ingår i Scientific Reports, 2025

• DOI för Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
• Ladda ner fulltext (pdf) av Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock

Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive Care Medicine Experimental, 2025

• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
• Ladda ner fulltext (pdf) av Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli

Bahnasawy, Salma M.; Skorup, Paul; Hanslin, Katja; Friberg, Lena et al.

Ingår i Cytokine, 2023

• DOI för Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli
• Ladda ner fulltext (pdf) av Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli

Qdenga®- A promising dengue fever vaccine; can it be recommended to non-immune travelers?

Angelin, Martin; Sjölin, Jan; Kahn, Fredrik; Ljunghill Hedberg, Anna et al.

Ingår i Travel Medicine and Infectious Disease, 2023

• DOI för Qdenga®- A promising dengue fever vaccine; can it be recommended to non-immune travelers?
• Ladda ner fulltext (pdf) av Qdenga®- A promising dengue fever vaccine; can it be recommended to non-immune travelers?

Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury

Luther, Tomas; Bülow-Anderberg, Sara; Persson, Patrik; Franzén, Stephanie et al.

Ingår i American Journal of Physiology - Renal Physiology, s. 571-580, 2023

• DOI för Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury
• Ladda ner fulltext (pdf) av Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury

Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial

Sundén-Cullberg, Jonas; Chen, Puran; Häbel, Henrike; Skorup, Paul et al.

Ingår i PLOS ONE, 2023

• DOI för Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial
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Enhanced bacterial clearance in early secondary sepsis in a porcine intensive care model.

Wilske, Frida; Skorup, Paul; Hanslin, Katja; Janols, Helena et al.

Ingår i Scientific Reports, 2023

• DOI för Enhanced bacterial clearance in early secondary sepsis in a porcine intensive care model.
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In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

Antoni, Gunnar; Lubberink, Mark; Sörensen, Jens; Lindström, Elin et al.

Ingår i Journal of Nuclear Medicine, s. 145-148, 2023

• DOI för In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES
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Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Skorup, Paul; Maccarana, Marco et al.

Ingår i Intensive Care Medicine Experimental, 2023

• DOI för Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
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The kinetics of SARS-CoV-2 viremia in COVID-19 patients receiving remdesivir

Krifors, Anders; Karlsson, Linda; Ekman, Martin; Lorant, Camilla et al.

Ingår i European Journal of Clinical Microbiology and Infectious Diseases, s. 951-958, 2023

• DOI för The kinetics of SARS-CoV-2 viremia in COVID-19 patients receiving remdesivir
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High molecular weight hyaluronan: a potential adjuvant to fluid resuscitation in abdominal sepsis?

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Dogné, Sophie; Flamion, Bruno et al.

Ingår i Shock, s. 763-770, 2023

• DOI för High molecular weight hyaluronan: a potential adjuvant to fluid resuscitation in abdominal sepsis?
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Evaluation of an extracorporeal ozone-based bactericide system for the treatment of Escherichia coli sepsis

Skorup, Paul; Fransson, Anette; Gustavsson, Jenny; Sjoholm, Johan et al.

Ingår i Intensive Care Medicine Experimental, 2022

• DOI för Evaluation of an extracorporeal ozone-based bactericide system for the treatment of Escherichia coli sepsis
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Intravenous anti-P. aeruginosa IgY-antibodies do not decrease pulmonary bacterial concentrations in a porcine model of ventilator-associated pneumonia

Otterbeck, Alexander; Skorup, Paul; Hanslin, Katja; Larsson, Anders et al.

Ingår i Innate Immunity, s. 224-234, 2022

• DOI för Intravenous anti-P. aeruginosa IgY-antibodies do not decrease pulmonary bacterial concentrations in a porcine model of ventilator-associated pneumonia
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Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial

Rosén, Jacob; von Oelreich, Erik; Fors, Diddi; Fagerlund, Malin Jonsson et al.

Ingår i Critical Care, 2021

• DOI för Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial
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Bronchially instilled IgY-antibodies did not decrease pulmonary p. aeruginosa concentration in experimental porcine pneumonia

Otterbeck, Alexander; Skorup, Paul; Hanslin, Katja; Larsson, Anders et al.

Ingår i Acta Anaesthesiologica Scandinavica, s. 656-663, 2021

• DOI för Bronchially instilled IgY-antibodies did not decrease pulmonary p. aeruginosa concentration in experimental porcine pneumonia
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Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

van der Heijden, Jaap; Kolliopoulos, Constantinos; Skorup, Paul; Sallisalmi, Marko et al.

Ingår i Intensive Care Medicine Experimental, 2021

• DOI för Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study
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Pre-exposure to mechanical ventilation and endotoxemia increases Pseudomonas aeruginosa growth in lung tissue during experimental porcine pneumonia

Sperber, Jesper; Nyberg, Axel; Krifors, Anders; Skorup, Paul et al.

Ingår i PLOS ONE, 2020

• DOI för Pre-exposure to mechanical ventilation and endotoxemia increases Pseudomonas aeruginosa growth in lung tissue during experimental porcine pneumonia
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Mode of Bacterial Killing Affects the Inflammatory Response and Associated Organ Dysfunctions in a Porcine E. coli Intensive Care Sepsis Model

Skorup, Paul; Maudsdotter, Lisa; Lipcsey, Miklós; Larsson, Anders et al.

Ingår i Critical care, 2020

• DOI för Mode of Bacterial Killing Affects the Inflammatory Response and Associated Organ Dysfunctions in a Porcine E. coli Intensive Care Sepsis Model

The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis

Hanslin, Katja; Sjölin, Jan; Skorup, Paul; Wilske, Frida et al.

Ingår i Intensive Care Medicine Experimental, 2019

• DOI för The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis
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Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model

Skorup, Paul; Maudsdotter, Lisa; Tano, Eva; Lipcsey, Miklós et al.

Ingår i Critical Care Medicine, 2018

• DOI för Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model

Pre-existing systemic inflammation attenuates bacterial clearance by the liver in porcine abdominal sepsis

Hanslin, Katja; Sjölin, Jan; Skorup, Paul; Wilske, Frida et al.

Ingår i Intensive Care Medicine Experimental, 2016

• DOI för Pre-existing systemic inflammation attenuates bacterial clearance by the liver in porcine abdominal sepsis

Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model.

Skorup, Paul; Maudsdotter, Lisa; Lipcsey, Miklós; Castegren, Markus et al.

Ingår i PLOS ONE, 2014

• DOI för Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model.
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Endotoxin tolerance variation over 24 h during porcine endotoxemia: association to changes in circulation and organ dysfunction

Castegren, Markus; Skorup, Paul; Lipcsey, Miklós; Larsson, Anders et al.

Ingår i PLOS ONE, 2013

• DOI för Endotoxin tolerance variation over 24 h during porcine endotoxemia: association to changes in circulation and organ dysfunction
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Differences in Organ Dysfunction in Endotoxin Tolerant Pigs Under Intensive Care Exposed to a Second Hit of Endotoxin

Castegren, Markus; Lipcsey, Miklós; Söderberg, Ewa; Skorup, Paul et al.

Ingår i Shock, s. 501-510, 2012

• DOI för Differences in Organ Dysfunction in Endotoxin Tolerant Pigs Under Intensive Care Exposed to a Second Hit of Endotoxin

Asthma management and asthma control in Sao Paulo, Brazil and Uppsala, Sweden: a questionnaire-based comparison

Skorup, Paul; Rizzo, Luiz Vicente; Machado-Boman, Lavinia; Janson, Christer

Ingår i The Clinical Respiratory Journal, s. 22-28, 2009

• DOI för Asthma management and asthma control in Sao Paulo, Brazil and Uppsala, Sweden: a questionnaire-based comparison

Antibacterial Effect and Inflammatory Response in Relation to Antibiotic Treatment of Sepsis

Skorup, Paul

2019

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Enhanced Bacterial Clearance at a Secondary Sepsis Challenge in an Endotoxin-tolerant Porcine Intensive Care Model

Skorup, Paul; Wilske, Frida; Hanslin, Katja; Larsson, Anders et al.

Mode of Bacterial Killing Affects the Inflammatory Response and Associated Organ Dysfunctions in a Porcine E. coli Intensive Care Sepsis Model

Skorup, Paul; Maudsdotter, Lisa; Lipcsey, Miklós; Larsson, Anders et al.

Intravenous anti-P. aeruginosa IgY antibodies increase bacterial concentration in porcine septic shock with bacteremia

Otterbeck, Alexander; Skorup, Paul; Larsson, Anders; Stålberg, Johan et al.