Xuan Wang

GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine

Ngamjariyawat, Anongnad; Cen, Jing; Wang, Xuan; Welsh, Nils

Ingår i International Journal of Molecular Sciences, 2024

• DOI för GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine
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Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

Dawed, Adem Y.; Mari, Andrea; Brown, Andrew; McDonald, Timothy J. et al.

Ingår i The Lancet Diabetes and Endocrinology, s. 33-41, 2023

• DOI för Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials
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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK

Elksnis, Andris; Schiffer, Tomas A.; Palm, Fredrik; Wang, Yun et al.

Ingår i Clinical Science, s. 2243-2263, 2021

• DOI för Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK

ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation

Wang, Xuan; Younis, Shady; Cen, Jing; Wang, Yun et al.

Ingår i Diabetologia, s. 2292-2305, 2021

• DOI för ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation
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The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells

Younis, Shady; Naboulsi, Rakan; Wang, Xuan; Cao, Xiaofang et al.

Ingår i The FASEB Journal, s. 10250-10266, 2020

• DOI för The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells
• Ladda ner fulltext (pdf) av The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells

GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine

Ngamjariyawat, Anongnad; Cen, Jing; Wang, Xuan; Welsh, Nils

Ingår i International Journal of Molecular Sciences, 2024

• DOI för GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine
• Ladda ner fulltext (pdf) av GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

Dawed, Adem Y.; Mari, Andrea; Brown, Andrew; McDonald, Timothy J. et al.

Ingår i The Lancet Diabetes and Endocrinology, s. 33-41, 2023

• DOI för Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials
• Ladda ner fulltext (pdf) av Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK

Elksnis, Andris; Schiffer, Tomas A.; Palm, Fredrik; Wang, Yun et al.

Ingår i Clinical Science, s. 2243-2263, 2021

• DOI för Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK

ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation

Wang, Xuan; Younis, Shady; Cen, Jing; Wang, Yun et al.

Ingår i Diabetologia, s. 2292-2305, 2021

• DOI för ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation
• Ladda ner fulltext (pdf) av ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation

The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells

Younis, Shady; Naboulsi, Rakan; Wang, Xuan; Cao, Xiaofang et al.

Ingår i The FASEB Journal, s. 10250-10266, 2020

• DOI för The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells
• Ladda ner fulltext (pdf) av The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells

Circulating Tissue Factor-Positive Procoagulant Microparticles in Patients with Type 1 Diabetes

Zhang, Chenghui; Ou, Qing; Gu, Yan; Cheng, Gaiping et al.

Ingår i Diabetes, Metabolic Syndrome and Obesity, s. 2819-2828, 2019

• DOI för Circulating Tissue Factor-Positive Procoagulant Microparticles in Patients with Type 1 Diabetes
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The protein synthesis inhibitor brusatol normalizes high-fat diet-induced glucose intolerance in male C57BL/6 mice: role of translation factor eIF5A hypusination

Turpaev, Kyril; Krizhanovskii, Camilla; Wang, Xuan; Sargsyan, Ernest et al.

Ingår i The FASEB Journal, s. 3510-3522, 2019

• DOI för The protein synthesis inhibitor brusatol normalizes high-fat diet-induced glucose intolerance in male C57BL/6 mice: role of translation factor eIF5A hypusination

A Comparison of Functional Features in Chinese and US Mobile Apps for Diabetes Self-Management: A Systematic Search in App Stores and Content Analysis

Wu, Yuan; Zhou, Yiling; Wang, Xuan; Zhang, Qi et al.

Ingår i JMIR mhealth and uhealth, 2019

• DOI för A Comparison of Functional Features in Chinese and US Mobile Apps for Diabetes Self-Management: A Systematic Search in App Stores and Content Analysis
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ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells

Wang, Xuan; Jiang, Lin; Wallerman, Ola; Younis, Shady et al.

Ingår i The FASEB Journal, s. 88-100, 2019

• DOI för ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells

The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro

Wang, Xuan; Elksnis, Andris; Wikström, Per; Walum, Erik et al.

Ingår i PLOS ONE, 2018

• DOI för The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro
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Determinants of progression of type 2 diabetes, a cross sectional analysis of UK BioBank

Wang, Xuan; Lonergan, M.; Donnelly, L.; Zhou, K. et al.

Ingår i Diabetologia, 2018

Effects of fatty acids on GLP-1-producing cells

Ntika, S.; Thombare, K.; Wang, Xuan; Krizhanovskii, C.

Ingår i Diabetologia, 2017

EndoC-beta H1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium

Krizhanovskii, Camilla; Kristinsson, Hjalti; Elksnis, Andris; Wang, Xuan et al.

Ingår i Islets, s. 43-48, 2017

• DOI för EndoC-beta H1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium

Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro

Wang, Xuan; Xie, Beichen; Qi, Yu; Wallerman, Ola et al.

Ingår i Scientific Reports, 2016

• DOI för Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro
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ZBED6 negatively regulates insulin content, glucose-stimulated insulin secretion, neuronal differentiation and cell aggregation in MIN6 cells

Wang, Xuan; Jiang, L.; Wallerman, Ola; Yu, Qian et al.

Ingår i Diabetologia, 2016

The H1-receptor antagonist cetirizine ameliorates high-fat diet-induced glucose intolerance in male C57BL/6 mice, but not diabetes outcome in female non-obese diabetic (NOD) mice

Anvari, Ebrahim; Wang, Xuan; Sandler, Stellan; Welsh, Nils

Ingår i Upsala Journal of Medical Sciences, s. 40-46, 2015

• DOI för The H1-receptor antagonist cetirizine ameliorates high-fat diet-induced glucose intolerance in male C57BL/6 mice, but not diabetes outcome in female non-obese diabetic (NOD) mice

Bcl-2 maintains the mitochondrial membrane potential, but fails to affect production of reactive oxygen species and endoplasmic reticulum stress, in sodium palmitate-induced beta-cell death

Wang, Xuan; Welsh, Nils

Ingår i Upsala Journal of Medical Sciences, s. 306-315, 2014

• DOI för Bcl-2 maintains the mitochondrial membrane potential, but fails to affect production of reactive oxygen species and endoplasmic reticulum stress, in sodium palmitate-induced beta-cell death
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Transcription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells

Wang, Xuan; Jiang, Lin; Wallerman, Ola; Engström, Ulla et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15997-16002, 2013

• DOI för Transcription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Mokhtari, Dariush; Åkerblom, Björn; Mehmeti, Ilir; Wang, Xuan et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 553-557, 2009

• DOI för Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Study of the Proliferation, Function and Death of Insulin-Producing Beta-Cells in vitro: Role of the Transcription Factor ZBED6

Wang, Xuan

2014

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