Eldar Abdurakhmanov

Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

Rajkovic, Andrei; Kanchugal, Sandesh; Abdurakhmanov, Eldar; Howard, Rebecca et al.

Ingår i PLOS ONE, 2023

• DOI för Amino acid substitutions in human growth hormone affect secondary structure and receptor binding
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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Ingår i Nature Cancer, s. 156, 2022

• DOI för Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
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Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Ingår i Science, s. 442-445, 2022

• DOI för Sequence specificity in DNA binding is mainly governed by association
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Ingår i Nucleic Acids Research, 2022

• DOI för Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
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Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Ingår i Analytical Chemistry, s. 10054-10061, 2022

• DOI för Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents
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Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

Rajkovic, Andrei; Kanchugal, Sandesh; Abdurakhmanov, Eldar; Howard, Rebecca et al.

Ingår i PLOS ONE, 2023

• DOI för Amino acid substitutions in human growth hormone affect secondary structure and receptor binding
• Ladda ner fulltext (pdf) av Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Ingår i Nature Cancer, s. 156, 2022

• DOI för Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
• Ladda ner fulltext (pdf) av Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Ingår i Science, s. 442-445, 2022

• DOI för Sequence specificity in DNA binding is mainly governed by association
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Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Ingår i Nucleic Acids Research, 2022

• DOI för Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
• Ladda ner fulltext (pdf) av Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Ingår i Analytical Chemistry, s. 10054-10061, 2022

• DOI för Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents
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Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Luttens, Andreas; Gullberg, Hjalmar; Abdurakhmanov, Eldar; Vo, Duy Duc et al.

Ingår i Journal of the American Chemical Society, s. 2905-2920, 2022

• DOI för Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
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Estimating Detection Limits of Potentiometric DNA sensors Using Surface Plasmon Resonance Analyses

Xu, Xingxing; Makaraviciute, Asta; Abdurakhmanov, Eldar; Werneling, Fredrik et al.

Ingår i ACS Sensors, s. 217-224, 2020

• DOI för Estimating Detection Limits of Potentiometric DNA sensors Using Surface Plasmon Resonance Analyses

Structural Changes of Mercaptohexanol Self-assembled Monolayers on Gold and their Influence on Impedimetric Aptamer Sensors

Xu, Xingxing; Makaraviciute, Asta; Kumar, Shalen; Wen, Chenyu et al.

Ingår i Analytical Chemistry, s. 14697-14704, 2019

• DOI för Structural Changes of Mercaptohexanol Self-assembled Monolayers on Gold and their Influence on Impedimetric Aptamer Sensors

Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Ingår i European Journal of Medicinal Chemistry, s. 453-464, 2018

• DOI för Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase

Abdurakhmanov, Eldar; Solbak, Sara Oie; Danielson, U. Helena

Ingår i Viruses, 2017

• DOI för Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase
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Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition

Solbak, Sara M.Ø.; Abdurakhmanov, Eldar; Vedeler, Anni; Danielson, U. Helena

Ingår i Virology Journal, 2017

• DOI för Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition
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Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 2603-2620, 2016

• DOI för Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Resolution of the Interaction Mechanisms and Characteristics of Non-nucleoside Inhibitors of Hepatitis C Virus Polymerase - Laying the Foundation for Discovery of Allosteric HCV Drugs

Winquist, Johan; Abdurakhmanov, Eldar; Baraznenok, Vera; Henderson, Ian et al.

Ingår i Antiviral Research, s. 356-368, 2013

• DOI för Resolution of the Interaction Mechanisms and Characteristics of Non-nucleoside Inhibitors of Hepatitis C Virus Polymerase - Laying the Foundation for Discovery of Allosteric HCV Drugs

Discovery and evaluation of direct acting antivirals against hepatitis C virus

Abdurakhmanov, Eldar

2015

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Target Engagement-Mediated Amplification for Monitoring Drug-Target Interactions in Situ

Al-Amin, Rasel A.; Johansson, Lars; Landegren, Nils; Löf, Liza et al.