Maria Norlin

Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik; Söderberg, Ola et al.

Ingår i Journal of Steroid Biochemistry and Molecular Biology, 2024

• DOI för Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D
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Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI för Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
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Enzymatic activation in vitamin D signaling: Past, present and future

Norlin, Maria; Wikvall, Kjell

Ingår i Archives of Biochemistry and Biophysics, 2023

• DOI för Enzymatic activation in vitamin D signaling: Past, present and future
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Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

Olsson, Frida; Sarri, Niki; Papadopoulos, Natalia; Lennartsson, Johan et al.

Ingår i Biochemistry and Biophysics Reports, 2022

• DOI för Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells
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A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Ingår i Nature Communications, 2022

• DOI för A method for Boolean analysis of protein interactions at a molecular level
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Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik; Söderberg, Ola et al.

Ingår i Journal of Steroid Biochemistry and Molecular Biology, 2024

• DOI för Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D
• Ladda ner fulltext (pdf) av Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI för Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
• Ladda ner fulltext (pdf) av Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

Olsson, Frida; Sarri, Niki; Papadopoulos, Natalia; Lennartsson, Johan et al.

Ingår i Biochemistry and Biophysics Reports, 2022

• DOI för Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells
• Ladda ner fulltext (pdf) av Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Ingår i Nature Communications, 2022

• DOI för A method for Boolean analysis of protein interactions at a molecular level
• Ladda ner fulltext (pdf) av A method for Boolean analysis of protein interactions at a molecular level

Effects of glucocorticoids on vitamin D₃-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Zayny, Ahmad; Almokhtar, Mokhtar; Wikvall, Kjell; Ljunggren, Östen et al.

Ingår i Molecular and Cellular Endocrinology, 2019

• DOI för Effects of glucocorticoids on vitamin D₃-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Vitamin D Analogues Tacalcitol and Calcipotriol Inhibit Proliferation and Migration of T98G Human Glioblastoma Cells

Emanuelsson, Ida; Wikvall, Kjell; Friman, Tomas; Norlin, Maria

Ingår i Neuroscience, s. 130-136, 2018

• DOI för Vitamin D Analogues Tacalcitol and Calcipotriol Inhibit Proliferation and Migration of T98G Human Glioblastoma Cells

Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: potential effects of vitamin D on brain steroidogenesis

Emanuelsson, Ida; Almokhtar, Mokhtar; Wikvall, Kjell; Gröndbladh, Alfhild et al.

Ingår i Neurochemistry International, s. 46-55, 2018

• DOI för Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: potential effects of vitamin D on brain steroidogenesis

Drug-mediated gene regulation of vitamin D₃ metabolism in primary human dermal fibroblasts

Norlin, Maria; Lundqvist, Johan; Ellfolk, Maria; Hellström Pigg, Maritta et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 59-63, 2017

• DOI för Drug-mediated gene regulation of vitamin D₃ metabolism in primary human dermal fibroblasts

Effects of osteoporosis-inducing drugs on vitamin D-related gene transcription and mineralization in MG-63 and Saos-2 cells

Wegler, Christine; Wikvall, Kjell; Norlin, Maria

Ingår i Basic & Clinical Pharmacology & Toxicology, 2016

• DOI för Effects of osteoporosis-inducing drugs on vitamin D-related gene transcription and mineralization in MG-63 and Saos-2 cells

Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Almokhtar, Mokhtar; Wikvall, Kjell; Ubhayasekera, S. J. Kumari A.; Bergquist, Jonas et al.

Ingår i Journal of Steroid Biochemistry and Molecular Biology, s. 178-188, 2016

• DOI för Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

Wicher, Grzegorz; Norlin, Maria

Ingår i Journal of Steroid Biochemistry and Molecular Biology, s. 21-27, 2015

• DOI för Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

Vitamin D-mediated regulation of CYP21A2 transcription – a novel mechanism for vitamin D action

Lundqvist, Johan; Wikvall, Kjell; Norlin, Maria

Ingår i Biochimica et Biophysica Acta - General Subjects, s. 1553-1559, 2012

• DOI för Vitamin D-mediated regulation of CYP21A2 transcription – a novel mechanism for vitamin D action

Effects of CYP7B1-related steroids on androgen receptor activation in different cell lines

Lundqvist, Johan; Norlin, Maria

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 973-979, 2012

• DOI för Effects of CYP7B1-related steroids on androgen receptor activation in different cell lines

Protective effects of 27-and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells

Emanuelsson, Ida; Norlin, Maria

Ingår i Neuroscience Letters, s. 44-48, 2012

• DOI för Protective effects of 27-and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells

Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism

Svenningsen, Åsa Fex; Wicher, Grzegorz; Lundqvist, Johan; Pettersson, Hanna et al.

Ingår i Neurochemistry International, s. 620-624, 2011

• DOI för Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism

Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway

Norlin, Maria; Pettersson, Hanna; Tang, Wanjin; Wikvall, Kjell

Ingår i Archives of Biochemistry and Biophysics, s. 236-241, 2011

• DOI för Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway

1α,25-Dihydroxyvitamin D₃ exerts tissue-specific effects on estrogen and androgen metabolism

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 263-270, 2011

• DOI för 1α,25-Dihydroxyvitamin D₃ exerts tissue-specific effects on estrogen and androgen metabolism

CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)

Norlin, Maria; Wikvall, Kjell

Ingår i Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2010

Effects of CYP7B1-mediated catalysis on estrogen receptor activation.

Pettersson, Hanna; Lundqvist, Johan; Norlin, Maria

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1090-1097, 2010

• DOI för Effects of CYP7B1-mediated catalysis on estrogen receptor activation.

1α,25-Dihydroxyvitamin D₃ affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1056-1062, 2010

• DOI för 1α,25-Dihydroxyvitamin D₃ affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells

CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1)

Norlin, Maria

Ingår i Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2009

Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells

Ellfolk, Maria; Norlin, Maria; Gyllensten, Katarina; Wikvall, Kjell

Ingår i Molecular Pharmacology, s. 1392-1399, 2009

• DOI för Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells

CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Pettersson, Hanna; Lundqvist, Johan; Oliw, Ernst; Norlin, Maria

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1206-1215, 2009

• DOI för CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 718-723, 2008

• DOI för Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme

Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling

Tang, Wanjin; Pettersson, Hanna; Norlin, Maria

Ingår i Journal of Steroid Biochemistry and Molecular Biology, s. 63-73, 2008

• DOI för Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling

Metabolism of a novel side chain modified Delta 8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1

Pettersson, Hanna; Norlin, Maria; Andersson, Ulla; Pikuleva, Irina et al.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 383-390, 2008

• DOI för Metabolism of a novel side chain modified Delta 8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1

CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling

Pettersson, Hanna; Holmberg, Lisa; Axelson, Magnus; Norlin, Maria

Ingår i The FEBS Journal, s. 1778-1789, 2008

• DOI för CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling

Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Hosseinpour, Fardin; Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 603-607, 2007

• DOI för Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Regulation of human CYP27A1 by estrogens and androgens in HepG2 and prostate cells

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Ingår i Archives of Biochemistry and Biophysics, s. 13-20, 2007

• DOI för Regulation of human CYP27A1 by estrogens and androgens in HepG2 and prostate cells

Isolation and properties of the CYP2D25 promoter: Transcriptional regulation by vitamin D3 metabolites

Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 568-572, 2006

• DOI för Isolation and properties of the CYP2D25 promoter: Transcriptional regulation by vitamin D3 metabolites

Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues

Tang, Wanjin; Eggertsen, Gösta; Chiang, John Y.L.; Norlin, Maria

Ingår i Journal of Steroid Biochemistry and Molecular Biology, s. 42-51, 2006

• DOI för Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues

Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 540-546, 2006

• DOI för Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 540-546, 2006

• DOI för Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells

Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Lennernäs, Hans; Jönsson, Mats; Norlin, Maria et al.

Ingår i Drug Metab Dispos, s. 984-92, 2006

Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein

Norlin, Maria; Chiang, John Y. L.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 158-164, 2004

• DOI för Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein

On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation

Norlin, Maria; von Bahr, Sara; Björkhem, Ingemar; Wikvall, Kjell

Ingår i Journal of Lipid Research, s. 1515-1522, 2003

• DOI för On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation

Metabolism of 4 beta -hydroxycholesterol in humans

Bodin, Karl; Andersson, Ulla; Rystedt, Eva; Ellis, Eva et al.

Ingår i Journal of Biological Chemistry, s. 31534-31540, 2002

• DOI för Metabolism of 4 beta -hydroxycholesterol in humans

Enzymatic activation in vitamin D signaling: Past, present and future

Norlin, Maria; Wikvall, Kjell

Ingår i Archives of Biochemistry and Biophysics, 2023

• DOI för Enzymatic activation in vitamin D signaling: Past, present and future
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Effects of vitamin D in the nervous system: Special focus on interaction with steroid hormone signalling and a possible role in the treatment of brain cancer

Norlin, Maria

Ingår i Journal of neuroendocrinology, 2020

• DOI för Effects of vitamin D in the nervous system: Special focus on interaction with steroid hormone signalling and a possible role in the treatment of brain cancer

Regulation of cellular steroid levels with special focus on oxysterol and estrogen metabolism

Norlin, Maria

Ingår i Future Lipidology, s. 337-346, 2008

• DOI för Regulation of cellular steroid levels with special focus on oxysterol and estrogen metabolism

Enzymes in the conversion of cholesterol into bile acids

Norlin, Maria; Wikvall, Kjell

Ingår i Current molecular medicine, s. 199-218, 2007

• DOI för Enzymes in the conversion of cholesterol into bile acids

Tissue-specific regulation of sex hormone biosynthesis and metabolism: novel aspects on hormonal signalling and maintenance of cellular steroid levels

Norlin, Maria; Wikvall, Kjell

Ingår i Sex Hormones, INTECH, 2011

Regulation of CYP enzymes in steroidogenesis with particular focus on cholesterol metabolism and vitamin D-related processes

Wikvall, Kjell; Ellfolk, Maria; Tang, Wanjin; Lundqvist, Johan et al.

Ingår i Proceedings of the 16th International Conference on Cytochrome P450, Nago, Okinawa, Japan, June 21-25, s. 177-182, 2009

Effects of glucocorticoids on vitamin D3 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Zayny, Ahmad; Almokhtar, Mokhtar; Wikvall, Kjell; Ljunggren, Östen et al.

Vitamin D metabolism in the nervous system: potential effects of glucocorticoids

Almokhtar, Mokhtar; Wikvall, Kjell; Norlin, Maria