Lucia Lazorova

The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Ingår i Powder Technology, 2025

• DOI för The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
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Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Pazesh, Samaneh; Lazorova, Lucia; Berggren, Jonas; Alderborn, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 488-504, 2016

• DOI för Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy
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The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 3-12, 2013

• DOI för The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction
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Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

Matsson, Elin M.; Eriksson, Ulf G.; Palm, Johan E.; Artursson, Per et al.

Ingår i Molecular Pharmaceutics, s. 4252-4262, 2013

• DOI för Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

mRNA expression of drug-transporting proteins along the human intestine and comparison with expression in Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Lazorova, Lucia et al.

2012

The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Ingår i Powder Technology, 2025

• DOI för The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
• Ladda ner fulltext (pdf) av The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Pazesh, Samaneh; Lazorova, Lucia; Berggren, Jonas; Alderborn, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 488-504, 2016

• DOI för Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy
• Ladda ner fulltext (pdf) av Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 3-12, 2013

• DOI för The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction
• Ladda ner fulltext (pdf) av The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

Matsson, Elin M.; Eriksson, Ulf G.; Palm, Johan E.; Artursson, Per et al.

Ingår i Molecular Pharmaceutics, s. 4252-4262, 2013

• DOI för Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

mRNA expression of drug-transporting proteins along the human intestine and comparison with expression in Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Lazorova, Lucia et al.

2012

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011

• DOI för Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

Ahlin, Gustav; Chen, L; Lazorova, Lucia; Chen, Ying et al.

Ingår i The Pharmacogenomics Journal, s. 400-411, 2011

• DOI för Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

CFTR and tight junctions in cultured bronchial epithelial cells

Nilsson, Harriet; Dragomir, Anca; Lazorova, Lucia; Johannesson, Marie et al.

Ingår i Experimental and molecular pathology (Print), s. 118-127, 2010

• DOI för CFTR and tight junctions in cultured bronchial epithelial cells

Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models

Linnankoski, Johanna; Mäkelä, Johanna; Palmgren, Joni; Mauriala, Timo et al.

Ingår i Journal of Pharmaceutical Sciences, s. 2166-2175, 2010

• DOI för Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models

Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Karlbom, Urban et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 269-277, 2006

• DOI för Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells

Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pK flux a method.

Avdeef, Alex; Artursson, Per; Neuhoff, Sibylle; Lazorova, Lucia et al.

Ingår i Eur J Pharm Sci, s. 333-49, 2005

Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium.

Hubatsch, Ina; Lazorova, Lucia; Vahlne, Anders; Artursson, Per

Ingår i Antimicrob Agents Chemother, s. 1087-92, 2005

Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.

Yasar, U; Annas, A; Svensson, J-O; Lazorova, L et al.

Ingår i Xenobiotica, s. 785-96, 2005

Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker ofMDR1-dependent drug efflux activity.

Taipalensuu, J; Tavelin, S; Lazorova, L; Svensson, AC et al.

Ingår i Eur J Pharm Sci, s. 69, 2004

Absorption classification of oral drugs based on molecular surface properties

Bergström, Christel A. S.; Strafford, Melissa; Lazorova, Lucia; Avdeef, Alex et al.

Ingår i Journal of Medicinal Chemistry, s. 558-570, 2003

• DOI för Absorption classification of oral drugs based on molecular surface properties

A New Principle for Tight Junction Modulation Based on Occludin Peptides

Tavelin, Staffan; Hashimoto, Kei; Lazorova, Lucia; Malkinson, John et al.

Ingår i Molecular Pharmacology, s. 1530-1540, 2003

• DOI för A New Principle for Tight Junction Modulation Based on Occludin Peptides

Absorption classification of oral drugs based on molecular surface properties

Bergström, Christel A S; Strafford, M; Lazorova, Lucia; Avdeef, A et al.

Ingår i Journal of Medicinal Chemistry, s. 558-570, 2003

• DOI för Absorption classification of oral drugs based on molecular surface properties

A new principle for tight junction modulation based on occludin peptides

Tavelin, Staffan; Hashimoto, Kei; Malkinson, J; Lazorova, Lucia et al.

Ingår i Molecular Pharmacology, s. 1530-1540, 2003

• DOI för A new principle for tight junction modulation based on occludin peptides

Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

Wong, AK; Ross, BP; Chan, YN; Artursson, Per et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 113-118, 2002

• DOI för Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

Novel lipoamino acid- and liposaccharide-based system for peptide delivery: Application for oral administration of tumor-selective somatostatin analogues

Toth, I; Malkinson, JP; Flinn, NS; Drouillat, B et al.

Ingår i Journal of Medicinal Chemistry, s. 4010-1013, 1999

• DOI för Novel lipoamino acid- and liposaccharide-based system for peptide delivery: Application for oral administration of tumor-selective somatostatin analogues

Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: Assessment of molecular weight dependence and demonstration of transport routes

Lindmark, T; Schipper, N; Lazorová, Lucia; de, Boer AG et al.

Ingår i Journal of drug targeting (Print), s. 215-223, 1998

• DOI för Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: Assessment of molecular weight dependence and demonstration of transport routes

Quantification and imaging of mannitol transport through Caco-2 cell monolayers using a positron-emitting tracer

Lazorova, Lucia; Gråsjö, Johan; Artursson, Per; Bergström, Mats et al.

Ingår i Pharmaceutical research, s. 1141-1144, 1998

• DOI för Quantification and imaging of mannitol transport through Caco-2 cell monolayers using a positron-emitting tracer

Transport of an influenza virus vaccine formulation (iscom) in Caco-2 cells

Lazorova, Lucia; Artursson, Per; Engström, Å; Sjölander, A

Ingår i American Journal of Physiology, 1996

Particle transcytosis across intestinal epithelial cells exposed for Yersinia pseudotuberculosis: gene expression analysis and functional studies

Ragnarsson, Eva GE; Göransson, Hanna; Rydåker, Maria; Magnusson, Karl-Eric et al.

Transcellular delivery of peptide antigens across the intestinal epithelial barrier. In Peptide and protein drug research

Artursson, P; Lazorova, L

1998