Otto Cars

Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

Årdal, Christine; Baraldi, Enrico; Busse, Reinhard; Castro, Rosa et al.

Ingår i The Lancet, 2024

• DOI för Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

The language of antimicrobial and antibiotic resistance is blocking global collective action

Karvanen, Matti; Cars, Otto

Ingår i Infectious Diseases, s. 487-495, 2024

• DOI för The language of antimicrobial and antibiotic resistance is blocking global collective action
• Ladda ner fulltext (pdf) av The language of antimicrobial and antibiotic resistance is blocking global collective action

The 2024 political declaration on antimicrobial resistance needs bold targets

Tangcharoensathien, Viroj; Cars, Otto; Lekagul, Angkana

Ingår i BMJ. British Medical Journal, 2024

• DOI för The 2024 political declaration on antimicrobial resistance needs bold targets

Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Ingår i Scientific Reports, 2024

• DOI för Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
• Ladda ner fulltext (pdf) av Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response

Ren, Mengying; So, Anthony D.; Chandy, Sujith J.; Mpundu, Mirfin et al.

Ingår i Journal of Law, Medicine & Ethics, s. 34-39, 2022

• DOI för Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response
• Ladda ner fulltext (pdf) av Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response

Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

Årdal, Christine; Baraldi, Enrico; Busse, Reinhard; Castro, Rosa et al.

Ingår i The Lancet, 2024

• DOI för Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

The language of antimicrobial and antibiotic resistance is blocking global collective action

Karvanen, Matti; Cars, Otto

Ingår i Infectious Diseases, s. 487-495, 2024

• DOI för The language of antimicrobial and antibiotic resistance is blocking global collective action
• Ladda ner fulltext (pdf) av The language of antimicrobial and antibiotic resistance is blocking global collective action

The 2024 political declaration on antimicrobial resistance needs bold targets

Tangcharoensathien, Viroj; Cars, Otto; Lekagul, Angkana

Ingår i BMJ. British Medical Journal, 2024

• DOI för The 2024 political declaration on antimicrobial resistance needs bold targets

Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Ingår i Scientific Reports, 2024

• DOI för Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
• Ladda ner fulltext (pdf) av Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response

Ren, Mengying; So, Anthony D.; Chandy, Sujith J.; Mpundu, Mirfin et al.

Ingår i Journal of Law, Medicine & Ethics, s. 34-39, 2022

• DOI för Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response
• Ladda ner fulltext (pdf) av Equitable Access to Antibiotics: A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response

Unavailability of old antibiotics threatens effective treatment for common bacterial infections

Tängdén, Thomas; Pulcini, Céline; Aagaard, Helle; Balasegaram, Manica et al.

Ingår i The Lancet - Infectious diseases, s. 242-244, 2018

• DOI för Unavailability of old antibiotics threatens effective treatment for common bacterial infections

Global governance of antimicrobial resistance

Rochford, Connor; Sridhar, Devi; Woods, Ngaire; Saleh, Zia et al.

Ingår i The Lancet, s. 1976-1978, 2018

• DOI för Global governance of antimicrobial resistance

Reply to Prim et al., "Is Colistin Susceptibility Testing Finally on the Right Track?"

Karvanen, Matti; Malmberg, Christer; Lagerbäck, Pernilla; Friberg, Lena E et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2018

• DOI för Reply to Prim et al., "Is Colistin Susceptibility Testing Finally on the Right Track?"

Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Khan, David; Lagerbäck, Pernilla; Malmberg, Christer; Kristoffersson, Anders et al.

Ingår i International Journal of Antimicrobial Agents, s. 399-406, 2018

• DOI för Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Colistin is Extensively Lost during Standard in Vitro Experimental Conditions

Karvanen, Matti; Malmberg, Christer; Lagerbäck, Pernilla; Friberg, Lena E et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2017

• DOI för Colistin is Extensively Lost during Standard in Vitro Experimental Conditions

Evaluation of automated time-lapse microscopy for assessment of in vitro activity of antibiotics

Ungphakorn, Wanchana; Malmberg, Christer; Lagerbäck, Pernilla; Cars, Otto et al.

Ingår i Journal of Microbiological Methods, s. 69-75, 2017

• DOI för Evaluation of automated time-lapse microscopy for assessment of in vitro activity of antibiotics

Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia

Pulcini, Celine; Mohrs, Simone; Beovic, Bojana; Gyssens, Inge et al.

Ingår i International Journal of Antimicrobial Agents, s. 98-101, 2017

• DOI för Forgotten antibiotics: a follow-up inventory study in Europe, the USA, Canada and Australia

Ensuring universal access to old antibiotics: a critical but neglected priority

Pulcini, C.; Beovic, B.; Beraud, G.; Carlet, J. et al.

Ingår i Clinical Microbiology and Infection, s. 590-592, 2017

• DOI för Ensuring universal access to old antibiotics: a critical but neglected priority

Assessment of early combination effects of colistin and meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii in dynamic time-kill experiments

Tängdén, Thomas; Karvanen, Matti; Friberg, Lena E.; Odenholt, Inga et al.

Ingår i Infectious Diseases, s. 521-527, 2017

• DOI för Assessment of early combination effects of colistin and meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii in dynamic time-kill experiments

Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK/PD model

Mohamed, Ami F; Kristoffersson, Anders; Karvanen, Matti; Nielsen, Elisabet et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1279-1290, 2016

• DOI för Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK/PD model

A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures

Malmberg, Christer; Yuen, Pikkei; Spaak, Johanna; Cars, Otto et al.

Ingår i PLOS ONE, 2016

• DOI för A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures
• Ladda ner fulltext (pdf) av A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures

UN High-Level Meeting on antimicrobials-what do we need?

Laxminarayan, Ramanan; Amabile-Cuevas, Carlos F.; Cars, Otto; Evans, Timothy et al.

Ingår i The Lancet, s. 218-220, 2016

• DOI för UN High-Level Meeting on antimicrobials-what do we need?

Prevalence of hypermutators among clinical Acinetobacter baumannii isolates

Komp Lindgren, Patricia; Higgins, Paul G; Seifert, Harald; Cars, Otto

Ingår i Journal of Antimicrobial Chemotherapy, s. 661-665, 2016

• DOI för Prevalence of hypermutators among clinical Acinetobacter baumannii isolates
• Ladda ner fulltext (pdf) av Prevalence of hypermutators among clinical Acinetobacter baumannii isolates

An international legal framework to address antimicrobial resistance

Hoffman, Steven J.; Outterson, Kevin; Rottingen, John-Arne; Cars, Otto et al.

Ingår i Bulletin of the World Health Organization, s. 66-66, 2015

• DOI för An international legal framework to address antimicrobial resistance

In Memoriam: William A. Craig

Theuretzbacher, Ursula; Ambrose, Paul G.; MacGowan, Alasdair P.; Andes, David R. et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 2971-2971, 2015

Changes in patterns of antibiotic use in Chinese public hospitals (2005-2012) and a benchmark comparison with Sweden in 2012

Sun, Jing; Shen, Xiao; Li, Meng; He, Liu et al.

Ingår i JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, s. 95-102, 2015

• DOI för Changes in patterns of antibiotic use in Chinese public hospitals (2005-2012) and a benchmark comparison with Sweden in 2012

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Khan, David D.; Lagerbäck, Pernilla; Cao, Sha; Lustig, Ulrika et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 3051-3060, 2015

• DOI för A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Antibiotic resistance: An ethical challenge

Littmann, Jasper; Buyx, Alena; Cars, Otto

Ingår i International Journal of Antimicrobial Agents, s. 359-361, 2015

• DOI för Antibiotic resistance: An ethical challenge

Pharmacodynamic studies of nitrofurantoin against common uropathogens

Komp Lindgren, Patricia; Klockars, Oscar; Malmberg, Christer; Cars, Otto

Ingår i Journal of Antimicrobial Chemotherapy, s. 1076-1082, 2015

• DOI för Pharmacodynamic studies of nitrofurantoin against common uropathogens

Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance

Daulaire, Nils; Bang, Abhay; Tomson, Goran; Kalyango, Joan N. et al.

Ingår i Journal of Law, Medicine & Ethics, s. 17-21, 2015

• DOI för Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance

Antibiotic use worldwide

Högberg, Liselotte Diaz; Muller, Arno; Zorzet, Anna; Monnet, Dominique L. et al.

Ingår i The Lancet - Infectious diseases, s. 1179-1180, 2014

• DOI för Antibiotic use worldwide

A pharmacokinetic/pharmacodynamic model developed for the effect of colistin on Pseudomonas aeruginosa in vitro with evaluation of population pharmacokinetic variability on simulated bacterial killing

Mohamed, Ami F; Cars, Otto; Friberg, Lena E

Ingår i Journal of Antimicrobial Chemotherapy, s. 1350-1361, 2014

• DOI för A pharmacokinetic/pharmacodynamic model developed for the effect of colistin on Pseudomonas aeruginosa in vitro with evaluation of population pharmacokinetic variability on simulated bacterial killing

Evaluation of Double- and Triple-Antibiotic Combinations for VIM- and NDM-Producing Klebsiella pneumoniae by In Vitro Time-Kill Experiment

Tängdén, Thomas; Hickman, Rachel A.; Forsberg, Petter; Lagerbäck, Pernilla et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 1757-1762, 2014

• DOI för Evaluation of Double- and Triple-Antibiotic Combinations for VIM- and NDM-Producing Klebsiella pneumoniae by In Vitro Time-Kill Experiment

Securing access to effective antibiotics for current and future generations. Whose responsibility?

Cars, Otto

Ingår i Upsala Journal of Medical Sciences, s. 209-214, 2014

• DOI för Securing access to effective antibiotics for current and future generations. Whose responsibility?

Mutant prevention concentrations of pradofloxacin for susceptible and mutant strains of Escherichia coli with reduced fluoroquinolone susceptibility

Marcusson, Linda L.; Lindgren, Patricia Komp; Olofsson, Sara K.; Hughes, Diarmaid et al.

Ingår i International Journal of Antimicrobial Agents, s. 354-357, 2014

• DOI för Mutant prevention concentrations of pradofloxacin for susceptible and mutant strains of Escherichia coli with reduced fluoroquinolone susceptibility

Consistent Global Approach on Reporting of Colistin Doses to Promote Safe and Effective Use

Nation, Roger L.; Li, Jian; Cars, Otto; Couet, William et al.

Ingår i Clinical Infectious Diseases, s. 139-+, 2014

• DOI för Consistent Global Approach on Reporting of Colistin Doses to Promote Safe and Effective Use

Cell-wall-inhibiting antibiotic combinations with activity against multidrug-resistant Klebsiella pneumoniae and Escherichia coli

Hickman, Rachel A.; Hughes, Diarmaid; Cars, Thomas; Malmberg, Christer et al.

Ingår i Clinical Microbiology and Infection, 2014

• DOI för Cell-wall-inhibiting antibiotic combinations with activity against multidrug-resistant Klebsiella pneumoniae and Escherichia coli

Antibiotic resistance: problems, progress, and prospects

Nathan, Carl; Cars, Otto

Ingår i New England Journal of Medicine, s. 1761-1763, 2014

• DOI för Antibiotic resistance: problems, progress, and prospects

Antibiotic resistance-the need for global solutions

Laxminarayan, Ramanan; Duse, Adriano; Wattal, Chand; Zaidi, Anita K. M. et al.

Ingår i The Lancet - Infectious diseases, s. 1057-1098, 2013

• DOI för Antibiotic resistance-the need for global solutions

Global survey of polymyxin use: A call for international guidelines

Wertheim, Heiman; Nguyen, Kinh Van; Levy Hara, Gabriel; Gelband, Hellen et al.

Ingår i JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, s. 131-134, 2013

• DOI för Global survey of polymyxin use: A call for international guidelines
• Ladda ner fulltext (pdf) av Global survey of polymyxin use: A call for international guidelines

Frequent emergence of porin-deficient subpopulations with reduced carbapenem susceptibility in ESBL-producing Escherichia coli during exposure to ertapenem in an in vitro pharmacokinetic model

Tängdén, Thomas; Adler, Marlen; Cars, Otto; Sandegren, Linus et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1319-1326, 2013

• DOI för Frequent emergence of porin-deficient subpopulations with reduced carbapenem susceptibility in ESBL-producing Escherichia coli during exposure to ertapenem in an in vitro pharmacokinetic model

Colistin methanesulfonate and colistin pharmacokinetics in critically ill patients receiving continuous venovenous hemodiafiltration

Karvanen, Matti; Plachouras, Diamantis; Friberg, Lena E; Paramythiotou, Elisabeth et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 668-671, 2013

• DOI för Colistin methanesulfonate and colistin pharmacokinetics in critically ill patients receiving continuous venovenous hemodiafiltration

3Rs for innovating novel antibiotics: sharing resources, risks, and rewards

So, Anthony D.; Ruiz-Esparza, Quentin; Gupta, Neha; Cars, Otto

Ingår i The BMJ, 2012

• DOI för 3Rs for innovating novel antibiotics: sharing resources, risks, and rewards

Pharmacokinetic-pharmacodynamic model for gentamicin and its adaptive resistance with predictions of dosing schedules in newborn infants

Mohamed, Ami F; Nielsen, Elisabet I; Cars, Otto; Friberg, Lena E

Ingår i Antimicrobial Agents and Chemotherapy, s. 179-188, 2012

• DOI för Pharmacokinetic-pharmacodynamic model for gentamicin and its adaptive resistance with predictions of dosing schedules in newborn infants

Application of a Loading Dose of Colistin Methanesulfonate in Critically Ill Patients: Population Pharmacokinetics, Protein Binding, and Prediction of Bacterial Kill

Mohamed, Ami Fazlin Syed; Karaiskos, Ilias; Plachouras, Diamantis; Karvanen, Matti et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 4241-4249, 2012

• DOI för Application of a Loading Dose of Colistin Methanesulfonate in Critically Ill Patients: Population Pharmacokinetics, Protein Binding, and Prediction of Bacterial Kill

Replik från Smittskyddsinstitutet och Strama-rådet: Nationella rekommendationer för behandling av faryngotonsillit gäller

Cars, Otto; Mölstad, Sigvard; Norman, Christer; Ternhag, Anders et al.

Ingår i Läkartidningen, s. 108-109, 2012

Radical reduction of cephalosporin use at a tertiary hospital after educational antibiotic intervention during an outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae

Tängdén, Thomas; Eriksson, Britt-Marie; Melhus, Åsa; Svennblad, Bodil et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1161-1167, 2011

• DOI för Radical reduction of cephalosporin use at a tertiary hospital after educational antibiotic intervention during an outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae

Fighting bacterial resistance at the root: need for adapted EMEA guidelines

Andremont, Antoine; Bonten, Marc; Kluytmans, Jan; Carmeli, Yehuda et al.

Ingår i The Lancet - Infectious diseases, s. 6-8, 2011

• DOI för Fighting bacterial resistance at the root: need for adapted EMEA guidelines

Pharmacokinetic/Pharmacodynamic (PK/PD) indices of antibiotics predicted by a semi-mechanistic PKPD model: a step toward model-based dose optimization

Nielsen, Elisabet I; Cars, Otto; Friberg, Lena E

Ingår i Antimicrobial Agents and Chemotherapy, s. 4619-4630, 2011

• DOI för Pharmacokinetic/Pharmacodynamic (PK/PD) indices of antibiotics predicted by a semi-mechanistic PKPD model: a step toward model-based dose optimization

Voriconazole-induced inhibition of the fungicidal activity of amphotericin B in Candida strains with reduced susceptibility to voriconazole: an Effect Not Predicted by the MIC Value Alone

Lignell, Anders; Löwdin, Elisabeth; Cars, Otto; Sanglard, Dominique et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 1629-1637, 2011

• DOI för Voriconazole-induced inhibition of the fungicidal activity of amphotericin B in Candida strains with reduced susceptibility to voriconazole: an Effect Not Predicted by the MIC Value Alone

Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model

Nielsen, Elisabet I.; Cars, Otto; Friberg, Lena E.

Ingår i Antimicrobial Agents and Chemotherapy, s. 1571-1579, 2011

• DOI för Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model

Posaconazole in human serum: A greater pharmacodynamic effect than predicted by the non-protein-bound serum concentration

Lignell, Anders; Löwdin, Elisabeth; Cars, Otto; Chryssanthou, Erja et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 3099-3104, 2011

• DOI för Posaconazole in human serum: A greater pharmacodynamic effect than predicted by the non-protein-bound serum concentration

Foreign Travel Is a Major Risk Factor for Colonization with Escherichia coli Producing CTX-M-Type Extended-Spectrum beta-Lactamases: a Prospective Study with Swedish Volunteers

Tängdén, Thomas; Cars, Otto; Melhus, Åsa; Löwdin, Elisabeth

Ingår i Antimicrobial Agents and Chemotherapy, s. 3564-3568, 2010

• DOI för Foreign Travel Is a Major Risk Factor for Colonization with Escherichia coli Producing CTX-M-Type Extended-Spectrum beta-Lactamases: a Prospective Study with Swedish Volunteers

Foreign travel is a major risk factor for colonization with Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases: a prospective study with Swedish volunteers.

Tängdén, Thomas; Cars, Otto; Melhus, Åsa; Löwdin, Elisabeth

Ingår i Antimicrobial Agents and Chemotherapy, s. 3564-3568, 2010

Tackling antibiotic resistance

So, Anthony D; Gupta, Neha; Cars, Otto

Ingår i BMJ. British Medical Journal, 2010

• DOI för Tackling antibiotic resistance

Serum and Cerebrospinal Fluid Levels of Colistin in Pediatric Patients

Antachopoulos, Charalampos; Karvanen, Matti; Iosifidis, Elias; Jansson, Britt et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 3985-3987, 2010

• DOI för Serum and Cerebrospinal Fluid Levels of Colistin in Pediatric Patients

Penicillin V och hur tre doser blev till två och sedan till tre igen: Historiken bakom behandling av otit, sinuit och faryngotonsillit

Giske, Christian G; Eriksson, Margareta; Hermansson, Ann; Kumlien, Jan et al.

Ingår i Läkartidningen, s. 2392-2395, 2010

Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

Sundqvist, Martin; Geli, Patricia; Andersson, Dan I.; Sjölund-Karlsson, M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 350-360, 2010

• DOI för Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

The time course of body temperature, serum amyloid A protein, C-reactive protein and interleukin-6 in patients with bacterial infection during the initial 3 days of antibiotic therapy

Lannergård, Anders; Viberg, Anders; Cars, Otto; Karlsson, Mats O. et al.

Ingår i Scandinavian Journal of Infectious Diseases, s. 663-671, 2009

• DOI för The time course of body temperature, serum amyloid A protein, C-reactive protein and interleukin-6 in patients with bacterial infection during the initial 3 days of antibiotic therapy

Doxycyklin är ingen ­hostmedicin: Antibiotika vid akut bronkit är både onödigt och riskabelt

Örtqvist, Åke; Holmberg, Hans; Norman, Christer; Cars, Otto

Ingår i Läkartidningen, s. 1666-7, 2009

Antibiotic resistance in China: a major future challenge

Heddini, Andreas; Cars, Otto; Qiang, Sun; Tomson, Göran

Ingår i The Lancet, s. 30-30, 2009

• DOI för Antibiotic resistance in China: a major future challenge

Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MS

Jansson, Britt; Karvanen, Matti; Cars, Otto; Plachouras, Diamantis et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, s. 760-767, 2009

• DOI för Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MS

Meeting the challenge of antibiotic resistance

Cars, Otto; Högberg, Liselotte Diaz; Murray, Mary; Nordberg, Olle et al.

Ingår i The BMJ, 2008

• DOI för Meeting the challenge of antibiotic resistance

Förkorta behandlingstiderna vid nedre urinvägsinfektion hos kvinnor och använd inte kinoloner!

Cars, Otto; Struwe, Johan; Norman, Christer; Sandberg, Torsten

Ingår i Läkartidningen, s. 1114-5, 2008

Strama-a Swedish working model for containment of antibiotic resistance.

Mölstad, S.; Cars, Otto; Struwe, Johan

Ingår i Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin, 2008

Alcohol-based hand-disinfection reduced children's absence from Swedish day care centers

Lennell, Anne; Kühlmann-Berenzon, Sharon; Geli, Patricia; Hedin, Katarina et al.

Ingår i Acta Paediatrica, s. 1672-80, 2008

• DOI för Alcohol-based hand-disinfection reduced children's absence from Swedish day care centers

Antimicrobial drug use and resistance in Europe

van de Sande-Bruinsma, Nienke; Grundmann, Hajo; Verloo, Didier; Tiemersma, Edine et al.

Ingår i Emerging Infectious Diseases, s. 1722-30, 2008

• DOI för Antimicrobial drug use and resistance in Europe

Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function

Viberg, Anders; Cars, Otto; Karlsson, Mats O; Jönsson, Siv

Ingår i Journal of clinical pharmacology, s. 1270-81, 2008

• DOI för Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function

Characterization of the inhibitory effect of voriconazole on the fungicidal activity of amphotericin B against Candida albicans in an in vitro kinetic model

Lignell, Anders; Löwdin, Elisabeth; Cars, Otto; Sjölin, Jan

Ingår i Journal of Antimicrobial Chemotherapy, s. 142-8, 2008

• DOI för Characterization of the inhibitory effect of voriconazole on the fungicidal activity of amphotericin B against Candida albicans in an in vitro kinetic model

Tissue concentrations: do we ever learn?

Mouton, Johan W.; Theuretzbacher, Ursula; Craig, William A.; Tulkens, Paul M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 235-237, 2008

• DOI för Tissue concentrations: do we ever learn?

Verkningslösa antibiotika dödligt hot även i Sverige

Olsen, Björn; Elisasson, Ingvar; Sjölin, Jan; Cars, Otto et al.

Ingår i DN-debatt, 2 mars, 2008

Dose-related selection of fluoroquinolone-resistant Escherichia coli

Olofsson, Sara K; Marcusson, Linda L.; Strömbäck, Ann; Hughes, Diarmaid et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 795-801, 2007

• DOI för Dose-related selection of fluoroquinolone-resistant Escherichia coli

Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments

Nielsen, Elisabet I.; Viberg, Anders; Löwdin, Elisabeth; Cars, Otto et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 128-136, 2007

• DOI för Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments

Pharmacodynamic effects of telavancin against methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains in the presence of human albumin or serum and in an in vitro kinetic model

Odenholt, Inga; Löwdin, Elisabeth; Cars, Otto

Ingår i Antimicrobial Agents and Chemotherapy, s. 3311-3316, 2007

• DOI för Pharmacodynamic effects of telavancin against methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains in the presence of human albumin or serum and in an in vitro kinetic model

Antibiotikaresistenta S aureus ger ökad dödlighet och dyrare sjukvård

Melander, Eva; Burman, Lars G; Cars, Otto

Ingår i Läkartidningen, s. 3052-3056, 2007

Optimizing drug exposure to minimize selection of antibiotic resistance

Olofsson, Sara K.; Cars, Otto

Ingår i Clinical Infectious Diseases, 2007

• DOI för Optimizing drug exposure to minimize selection of antibiotic resistance

A new in-vitro kinetic model to study the pharmacodynamics of antifungal agents: inhibition of the fungicidal activity of amphotericin B against Candida albicans by voriconazole

Lignell, Anders; Johansson, A.; Löwdin, Elisabeth; Cars, Otto et al.

Ingår i Clinical Microbiology and Infection, s. 613-619, 2007

• DOI för A new in-vitro kinetic model to study the pharmacodynamics of antifungal agents: inhibition of the fungicidal activity of amphotericin B against Candida albicans by voriconazole

Lågdos-DT bättre än vanlig röntgen vid diagnostik av rinosinuit - en kommentar från Läkemedelsverket och Strama

Ahlqvist Rastad, Jane; Cars, Otto; Norman, Christer

Ingår i Läkartidningen, s. 3478, 2007

STRAMA håller fast vid Otitkonsensus

Norman, Christer; Cars, Otto; Söderström, Ann; Groth, Anita Bylander et al.

Ingår i Läkartidningen, s. 1996-1997, 2007

A population pharmacokinetic model for cefuroxime using cystatin C as a marker of renal function

Viberg, Anders; Lannergård, Anders; Larsson, Anders; Cars, Otto et al.

Ingår i British Journal of Clinical Pharmacology, s. 297-303, 2006

• DOI för A population pharmacokinetic model for cefuroxime using cystatin C as a marker of renal function

Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model

Odenholt, Inga; Cars, Otto

Ingår i Journal of Antimicrobial Chemotherapy, s. 960-965, 2006

• DOI för Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model

National campaigns to improve antibiotic use.

Goossens, Herman; Guillemot, Didier; Ferech, Matus; Schlemmer, Benoit et al.

Ingår i Eur J Clin Pharmacol, s. 373-9, 2006

Kinoloner - bot som blivit hot: Accelererande resistensutveckling kräver skärpta indikationer

Lytsy, Birgitta; Cars, Otto; Torell, Erik

Ingår i Läkartidningen, s. 3651-3659, 2005

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update.

Mouton, Johan W; Dudley, Michael N; Cars, Otto; Derendorf, Hartmut et al.

Ingår i J Antimicrob Chemother, s. 601-7, 2005

Pharmacodynamic studies of moxifloxacin and erythromycin against intracellular Legionella pneumophila in an in vitro kinetic model.

Tano, E; Cars, O; Lowdin, E

Ingår i J Antimicrob Chemother, s. 240-2, 2005

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli.

Olofsson, Sara K; Geli, Patricia; Andersson, Dan I; Cars, Otto

Ingår i Antimicrob Agents Chemother, s. 5081-91, 2005

Reduction in outpatient antibiotic sales for pre-school children: interrupted time series analysis of weekly antibiotic sales data in Sweden 1992-2002.

Hogberg, Liselotte; Oke, Thimothy; Geli, Patricia; Lundborg, Cecilia et al.

Ingår i J Antimicrob Chemother, s. 208-15, 2005

Pharmacodynamic studies of amoxicillin against Streptococcus pneumoniae: comparison of a new pharmacokinetically enhanced formulation (2000 mg twice daily) with standard dosage regimens.

Odenholt, Inga; Cars, Otto; Löwdin, Elisabeth

Ingår i J Antimicrob Chemother, s. 1062-6, 2004

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Gustafsson, Ingegerd; Sjölund, Maria; Torell, Erik; Johannesson, Marie et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 645-650, 2003

• DOI för Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Resetting the agenda for antibiotic resistance through a health systems perspective

Cars, Otto; Chandy, Sujith J.; Mpundu, Mirfin; Peralta, Arturo Quizhpe et al.

Ingår i The Lancet Global Health, 2021

• DOI för Resetting the agenda for antibiotic resistance through a health systems perspective
• Ladda ner fulltext (pdf) av Resetting the agenda for antibiotic resistance through a health systems perspective

Antimicrobial resistance-a threat to the world's sustainable development

Jasovsky, Dusan; Littmann, Jasper; Zorzet, Anna; Cars, Otto

Ingår i Upsala Journal of Medical Sciences, s. 159-164, 2016

• DOI för Antimicrobial resistance-a threat to the world's sustainable development
• Ladda ner fulltext (pdf) av Antimicrobial resistance-a threat to the world's sustainable development

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

Nation, Roger L; Li, Jian; Cars, Otto; Couet, William et al.

Ingår i The Lancet - Infectious diseases, s. 225-234, 2015

• DOI för Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

Access, excess, and ethics—towards a sustainable distribution model for antibiotics

Heyman, Gabriel; Cars, Otto; Bejarano, Maria-Teresa; Peterson, Stefan

Ingår i Upsala Journal of Medical Sciences, s. 134-141, 2014

• DOI för Access, excess, and ethics—towards a sustainable distribution model for antibiotics

Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now

Freire-Moran, Laura; Aronsson, Bo; Manz, Chris; Gyssens, Inge C. et al.

Ingår i Drug resistance updates, s. 118-124, 2011

• DOI för Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now

Protein Binding: Do We Ever Learn?

Zeitlinger, Markus A.; Derendorf, Hartmut; Mouton, Johan W.; Cars, Otto et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 3067-3074, 2011

• DOI för Protein Binding: Do We Ever Learn?

The global need for effective antibiotics: moving towards concerted action

Cars, Otto; Hedin, Anna; Heddini, Andreas

Ingår i Drug resistance updates, s. 68-69, 2011

• DOI för The global need for effective antibiotics: moving towards concerted action

The global need for effective antibiotics: challenges and recent advances

Högberg, Liselotte Diaz; Heddini, Andreas; Cars, Otto

Ingår i TIPS - Trends in Pharmacological Sciences, s. 509-515, 2010

• DOI för The global need for effective antibiotics: challenges and recent advances

Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme

Mölstad, S.; Erntell, M.; Hanberger, H.; Melander, E. et al.

Ingår i The Lancet - Infectious diseases, s. 125-132, 2008

• DOI för Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme

Clinical and economic impact of common multidrug-resistant gram-negative bacilli

Giske, Christian G.; Monnet, Dominique L.; Cars, Otto; Carmeli, Yehuda

Ingår i Antimicrobial Agents and Chemotherapy, s. 813-821, 2008

• DOI för Clinical and economic impact of common multidrug-resistant gram-negative bacilli