Per Andrén

Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues

Lee, Yea-Rin; Kaya, Ibrahim; Wik, Elin; Baijnath, Sooraj et al.

Ingår i Analytical Chemistry, s. 1338-1346, 2025

• DOI för Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
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Spatial multimodal analysis of transcriptomes and metabolomes in tissues

Vicari, Marco; Mirzazadeh, Reza; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i Nature Biotechnology, s. 1046-1050, 2024

• DOI för Spatial multimodal analysis of transcriptomes and metabolomes in tissues
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Spatial multiomic insights into acute cocaine exposure

Nezhyva, Mariya; Shahen-Zoabi, Samah; Kabirova, Marina; Bentov-Arav, Einav et al.

Ingår i PNAS Nexus, 2024

• DOI för Spatial multiomic insights into acute cocaine exposure
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Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions

Mácha, Hynek; Luptáková, Dominika; Juránek, Ivo; Andrén, Per E. et al.

Ingår i ACS Chemical Neuroscience, s. 2811-2821, 2024

• DOI för Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes

Vallianatou, Theodosia; Angerer, Tina B.; Kaya, Ibrahim; Nilsson, Anna et al.

Ingår i ACS Chemical Neuroscience, s. 2822-2829, 2024

• DOI för Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
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Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues

Lee, Yea-Rin; Kaya, Ibrahim; Wik, Elin; Baijnath, Sooraj et al.

Ingår i Analytical Chemistry, s. 1338-1346, 2025

• DOI för Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
• Ladda ner fulltext (pdf) av Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues

Spatial multimodal analysis of transcriptomes and metabolomes in tissues

Vicari, Marco; Mirzazadeh, Reza; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i Nature Biotechnology, s. 1046-1050, 2024

• DOI för Spatial multimodal analysis of transcriptomes and metabolomes in tissues
• Ladda ner fulltext (pdf) av Spatial multimodal analysis of transcriptomes and metabolomes in tissues

Spatial multiomic insights into acute cocaine exposure

Nezhyva, Mariya; Shahen-Zoabi, Samah; Kabirova, Marina; Bentov-Arav, Einav et al.

Ingår i PNAS Nexus, 2024

• DOI för Spatial multiomic insights into acute cocaine exposure
• Ladda ner fulltext (pdf) av Spatial multiomic insights into acute cocaine exposure

Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions

Mácha, Hynek; Luptáková, Dominika; Juránek, Ivo; Andrén, Per E. et al.

Ingår i ACS Chemical Neuroscience, s. 2811-2821, 2024

• DOI för Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes

Vallianatou, Theodosia; Angerer, Tina B.; Kaya, Ibrahim; Nilsson, Anna et al.

Ingår i ACS Chemical Neuroscience, s. 2822-2829, 2024

• DOI för Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes
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Hydrogen production by a fully de novo enzyme

Berglund, Sigrid; Bassy, Clara; Kaya, Ibrahim; Andrén, Per E. et al.

Ingår i Dalton Transactions, s. 12905-12916, 2024

• DOI för Hydrogen production by a fully de novo enzyme
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Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging

Lodén, Henrik; Schembri, Luke S; Nilsson, Anna; Kaya, Ibrahim et al.

Ingår i Chemical Communications, s. 9238-9241, 2024

• DOI för Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging

The involvement of cyclotides in the heavy metal tolerance of Viola spp.

Sychta, Klaudia; Slomka, Aneta; Shariatgorji, Reza; Andrén, Per E. et al.

Ingår i Scientific Reports, 2024

• DOI för The involvement of cyclotides in the heavy metal tolerance of Viola spp.
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Regional Changes in Brain Biomolecular Markers in a Collagen-Induced Arthritis Rat Model

Millen, Aletta M. E.; Maluleke, Tshiamo T.; Pienaar, Leandrie; Sallie, Farhanah N. et al.

Ingår i Biology, 2024

• DOI för Regional Changes in Brain Biomolecular Markers in a Collagen-Induced Arthritis Rat Model
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GABA-mediated inhibition of human CD4⁺ T cell functions is enhanced by insulin but impaired by high glucose levels

Jin, Zhe; Hammoud, Hayma; Bhandage, Amol; Korol, Sergiy Vasylyovych et al.

Ingår i EBioMedicine, 2024

• DOI för GABA-mediated inhibition of human CD4⁺ T cell functions is enhanced by insulin but impaired by high glucose levels
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Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model

Kaya, Ibrahim; Nilsson, Anna; Luptakova, Dominika; He, Yachao et al.

Ingår i npj Parkinson's Disease, 2023

• DOI för Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model
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Label-Free Quantitative Thermal Proteome Profiling Reveals Target Transcription Factors with Activities Modulated by MC3R Signaling

Sandbaumhuter, Friederike A.; Nezhyva, Mariya; Andrén, Per E.; Jansson, Erik T.

Ingår i Analytical Chemistry, s. 15400-15408, 2023

• DOI för Label-Free Quantitative Thermal Proteome Profiling Reveals Target Transcription Factors with Activities Modulated by MC3R Signaling
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Rapid Metabolic Profiling of 1 ÎŒL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson's Disease

Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik; Shariatgorji, Reza et al.

Ingår i Analytical Chemistry, s. 18352-18360, 2023

• DOI för Rapid Metabolic Profiling of 1 ÎŒL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson's Disease
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Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents

He, Yachao; Kaya, Ibrahim; Shariatgorji, Reza; Lundkvist, Johan et al.

Ingår i Nature Communications, 2023

• DOI för Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents
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Zero-Degree Celsius Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry

Aerts, Jordan; Andrén, Per E.; Jansson, Erik T.

Ingår i Analytical Chemistry, s. 1149-1158, 2023

• DOI för Zero-Degree Celsius Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry

Enantioselective CE–MS analysis of ketamine metabolites in urine

Sandbaumhüter, Friederike A.; Aerts, Jordan T.; Theurillat, Regula; Andrén, Per E. et al.

Ingår i Electrophoresis, s. 125-134, 2023

• DOI för Enantioselective CE–MS analysis of ketamine metabolites in urine
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Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis-Mass Spectrometry

Aerts, Jordan; Andrén, Per E.; Jansson, Erik T.

Ingår i Journal of Proteome Research, s. 1377-1380, 2023

• DOI för Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis-Mass Spectrometry
• Ladda ner fulltext (pdf) av Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis-Mass Spectrometry

RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins

Stenum, Thomas Søndergaard; Kumar, Ankith D.; Sandbaumhueter, Friederike A.; Kjellin, Jonas et al.

Ingår i Nucleic Acids Research, s. 4572-4587, 2023

• DOI för RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins
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On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging

Kaya, Ibrahim; Schembri, Luke S; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i Journal of the American Society for Mass Spectrometry, s. 836-846, 2023

• DOI för On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging
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Well-Plate muFASP for Proteomic Analysis of Single Pancreatic Islets

Sandbaumhüter, Friederike A.; Nezhyva, Mariya; Eriksson, Olle; Engberg, Adam et al.

Ingår i Journal of Proteome Research, s. 1167-1174, 2022

• DOI för Well-Plate muFASP for Proteomic Analysis of Single Pancreatic Islets
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The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Sybilska, Anna et al.

Ingår i Scientific Reports, 2022

• DOI för The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite
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The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Shariatgorji, Reza et al.

Ingår i PLANTS, 2022

• DOI för The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures
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Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia

Hulme, Heather; Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Reza et al.

Ingår i npj Parkinson's Disease, 2022

• DOI för Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia
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Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging

Strittmatter, Nicole; Richards, Frances M.; Race, Alan M.; Ling, Stephanie et al.

Ingår i Analytical Chemistry, s. 1795-1803, 2022

• DOI för Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

Fridjonsdottir, Elva; Vallianatou, Theodosia; Mantas, Ioannis; Shariatgorji, Reza et al.

Ingår i ACS Chemical Biology, s. 147-158, 2022

• DOI för Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems
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Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide

Rofo, Fadi; Sandbaumhüter, Friederike A.; Chourlia, Aikaterini; Metzendorf, Nicole G. et al.

Ingår i ACS Chemical Neuroscience, s. 2529-2541, 2021

• DOI för Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide
• Ladda ner fulltext (pdf) av Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide

Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain

Vallianatou, Theodosia; Shariatgorji, Reza; Nilsson, Anna; Karlgren, Maria et al.

Ingår i ACS Chemical Neuroscience, s. 1811-1823, 2021

• DOI för Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain
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TAAR1-Dependent and-Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition

Mantas, Ioannis; Vallianatou, Theodosia; Yang, Yunting; Shariatgorji, Mohammadreza et al.

Ingår i Biological Psychiatry, s. 16-27, 2021

• DOI för TAAR1-Dependent and-Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition
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Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Luptáková, Dominika; Vallianatou, Theodosia; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i Molecular Psychiatry, s. 7732-7745, 2021

• DOI för Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.
• Ladda ner fulltext (pdf) av Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

Shariatgorji, Reza; Nilsson, Anna; Fridjonsdottir, Elva; Strittmatter, Nicole et al.

Ingår i Nature Protocols, s. 3298-3321, 2021

• DOI för Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice

Becker, Katja; Aranzana-Climent, Vincent; Cao, Sha; Nilsson, Anna et al.

Ingår i Clinical Microbiology and Infection, s. 1315-1321, 2021

• DOI för Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice
• Ladda ner fulltext (pdf) av Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis

Becker, Katja; Cao, Sha; Nilsson, Anna; Erlandsson, Maria et al.

Ingår i EBioMedicine, 2021

• DOI för Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis
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Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

Ingår i Science Advances, 2021

• DOI för Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia
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Cyclotide host-defense tailored for species and environments in violets from the Canary Islands

Slazak, Blazej; Kaltenböck, Klara; Steffen, Karin; Rogala, Martyna et al.

Ingår i Scientific Reports, 2021

• DOI för Cyclotide host-defense tailored for species and environments in violets from the Canary Islands
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Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37

Zhang, Xiaoqun; Mantas, Ioannis; Fridjonsdottir, Elva; Andrén, Per E. et al.

Ingår i Frontiers in Aging Neuroscience, 2020

• DOI för Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37
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Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

Ingår i Frontiers in Pharmacology, 2020

• DOI för Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses
• Ladda ner fulltext (pdf) av Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

mu Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease

Bezard, Erwan; Li, Qin; Hulme, Heather; Fridjonsdottir, Elva et al.

Ingår i Journal of Neuroscience, s. 6812-6819, 2020

• DOI för mu Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease

Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging

Hamm, Gregory R.; Bäckström, Erica; Brülls, Mikael; Nilsson, Anna et al.

Ingår i Journal of Aerosol Medicine, s. 43-53, 2020

• DOI för Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

Ingår i Neurobiology of Disease, 2020

• DOI för Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy
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Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds

Shariatgorji, Mohammadreza; Nilsson, Anna; Strittmatter, Nicole; Vallianatou, Theodosia et al.

Ingår i Journal of the American Society for Mass Spectrometry, s. 2553-2557, 2020

• DOI för Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers

Källback, Patrik; Vallianatou, Theodosia; Nilsson, Anna; Shariatgorji, Mohammadreza et al.

Ingår i Analytical Chemistry, s. 14676-14684, 2020

• DOI för Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers
• Ladda ner fulltext (pdf) av Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers

Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

Shariatgorji, Mohammadreza; Nilsson, Anna; Fridjonsdottir, Elva; Vallianatou, Theodosia et al.

Ingår i Nature Methods, s. 1021-1028, 2019

• DOI för Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging

Sugiyama, Eiji; Guerrini, Matteo M.; Honda, Kurara; Hattori, Yuko et al.

Ingår i iScience, s. 359-+, 2019

• DOI för Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging
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Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition

Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna; Fridjonsdottir, Elva et al.

Ingår i Neuropsychopharmacology, s. 2091-2098, 2019

• DOI för Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition
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alpha-synuclein-lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson's disease patients

Paslawski, Wojciech; Zareba-Paslawska, Justyna; Zhang, Xiaoqun; Holzl, Katharina et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15226-15235, 2019

• DOI för alpha-synuclein-lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson's disease patients
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Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

Jacobsson, Erik; Andersson, Håkan S.; Strand, Malin; Peigneur, Steve et al.

Ingår i Scientific Reports, 2018

• DOI för Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
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How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System

Slazak, Blazej; Kapusta, Malgorzata; Strömstedt, Adam A.; Slomka, Aneta et al.

Ingår i Frontiers in Plant Science, 2018

• DOI för How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System
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Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or beta-Phenylethylamine

Zhang, Xiaoqun; Mantas, Ioannis; Alvarsson, Alexandra; Yoshitake, Takashi et al.

Ingår i Frontiers in Pharmacology, 2018

• DOI för Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or beta-Phenylethylamine

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level

Charkoftaki, Georgia; Rattray, Nicholas J. W.; Andrén, Per E.; Caprioli, Richard M. et al.

Ingår i Human Genomics, 2018

• DOI för Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level
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A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability

Vallianatou, Theodosia; Strittmatter, Nicole; Nilsson, Anna; Shariatgorji, Mohammadreza et al.

Ingår i NeuroImage, s. 808-816, 2018

• DOI för A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability

Editorial and Review: 29th ASMS Sanibel Conference on Mass Spectrometry-Peptidomics: Bridging the Gap between Proteomics and Metabolomics by MS

Li, Lingjun; Andrén, Per E.; Sweedler, Jonathan V.

Ingår i Journal of the American Society for Mass Spectrometry, s. 801-806, 2018

• DOI för Editorial and Review: 29th ASMS Sanibel Conference on Mass Spectrometry-Peptidomics: Bridging the Gap between Proteomics and Metabolomics by MS

Uncovering the regional localization of inhaled salmeterol retention in the lung

Bäckström, Erica; Hamm, Gregory; Nilsson, Anna; Fihn, Britt-Marie et al.

Ingår i Drug Delivery, s. 838-845, 2018

• DOI för Uncovering the regional localization of inhaled salmeterol retention in the lung
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Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging

Swales, John G.; Dexter, Alex; Hamm, Gregory; Nilsson, Anna et al.

Ingår i Analytical Chemistry, s. 6051-6058, 2018

• DOI för Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging

A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging

Källback, Patrik; Nilsson, Anna; Andrén, Per E.

Ingår i Analytical Chemistry, s. 3676-3682, 2018

• DOI för A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging

Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection

Hulme, Heather E.; Meikle, Lynsey M.; Wessel, Hannah; Strittmatter, Nicole et al.

Ingår i Scientific Reports, 2017

• DOI för Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection
• Ladda ner fulltext (pdf) av Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

Nilsson, Anna; Peric, Alexandra; Strimfors, Marie; Goodwin, Richard J. A. et al.

Ingår i Scientific Reports, 2017

• DOI för Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis
• Ladda ner fulltext (pdf) av Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

De Rosa, Maria; Lu, Lu; Zamaratski, Edouard; Szałaj, Natalia et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 897-911, 2017

• DOI för Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)
• Ladda ner fulltext (pdf) av Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry

Shariatgorji, Mohammadreza; Nilsson, Anna; Bonta, Maximilian; Gan, Jinrui et al.

Ingår i Methods, s. 86-92, 2016

• DOI för Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry

Investigating drug-induced toxicity in tissue samples using mass spectrometry imaging

Andrén, Per E.; Nilsson, Anna; Shariatgorji, Mohammadreza; Goodwin, Richard

Ingår i Toxicology Letters, 2016

• DOI för Investigating drug-induced toxicity in tissue samples using mass spectrometry imaging

Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo

Ashton, Susan; Song, Young Ho; Nolan, Jim; Cadogan, Elaine et al.

Ingår i Science Translational Medicine, 2016

• DOI för Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo

Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections

Goodwin, Richard J. A.; Nilsson, Anna; Mackay, C. Logan; Swales, John G. et al.

Ingår i Journal of Biomolecular Screening, s. 187-193, 2016

• DOI för Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections

Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

Shariatgorji, Mohammadreza; Strittmatter, Nicole; Nilsson, Anna; Kallbäck, Patrik et al.

Ingår i NeuroImage, s. 129-138, 2016

• DOI för Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

msIQuant - Quantitation Software for Mass Spectrometry Imaging Enabling Fast Access, Visualization, and Analysis of Large Data Sets

Källback, Patrik; Nilsson, Anna; Shariatgorji, Mohammadreza; Andrén, Per E.

Ingår i Analytical Chemistry, s. 4346-4353, 2016

• DOI för msIQuant - Quantitation Software for Mass Spectrometry Imaging Enabling Fast Access, Visualization, and Analysis of Large Data Sets

An introduction to MS imaging in drug discovery and development

Lodén, Henrik; Shariatgorji, Mohammadreza; Nilsson, Anna; Andrén, Per E.

Ingår i Bioanalysis, s. 2621-2627, 2015

• DOI för An introduction to MS imaging in drug discovery and development

Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain

Watanabe, Hiroyuki; Fitting, Sylvia; Hussain, Muhammad; Kononenko, Olga et al.

Ingår i Cerebral Cortex, s. 97-108, 2015

• DOI för Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain
• Ladda ner fulltext (pdf) av Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain

Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome

Nilsson, Carol L.; Mostovenko, Ekaterina; Lichti, Cheryl F.; Ruggles, Kelly et al.

Ingår i Journal of Proteome Research, s. 603-608, 2015

• DOI för Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome

Investigating Nephrotoxicity of Polymyxin Derivatives by Mapping Renal Distribution Using Mass Spectrometry Imaging

Nilsson, Anna; Goodwin, Richard J. A.; Swales, John G.; Gallagher, Richard et al.

Ingår i Chemical Research in Toxicology, s. 1823-1830, 2015

• DOI för Investigating Nephrotoxicity of Polymyxin Derivatives by Mapping Renal Distribution Using Mass Spectrometry Imaging

Discussion point: reporting guidelines for mass spectrometry imaging

McDonnell, Liam A.; Roempp, Andreas; Balluff, Benjamin; Heeren, Ron M. A. et al.

Ingår i Analytical and Bioanalytical Chemistry, s. 2035-2045, 2015

• DOI för Discussion point: reporting guidelines for mass spectrometry imaging

Imaging AZD1152HQPA Accurin (TM) nanoparticle accumulation in preclinical tumors

Goodwin, Richard; Swales, John; Nilsson, Anna; Andrén, Per et al.

Ingår i Cancer Research, 2015

• DOI för Imaging AZD1152HQPA Accurin (TM) nanoparticle accumulation in preclinical tumors

Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases

Akhtar, Malik N.; Southey, Bruce R.; Andrén, Per E.; Sweedler, Jonathan V. et al.

Ingår i PLOS ONE, 2014

• DOI för Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases
• Ladda ner fulltext (pdf) av Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases

Identification of best indicators of peptide-spectrum match using a permutation resampling approach

Akhtar, Malik N.; Southey, Bruce R.; Andrén, Per E.; Sweedler, Jonathan V. et al.

Ingår i Journal of Bioinformatics and Computational Biology, s. 1440001, 2014

• DOI för Identification of best indicators of peptide-spectrum match using a permutation resampling approach
• Ladda ner fulltext (pdf) av Identification of best indicators of peptide-spectrum match using a permutation resampling approach

Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections

Shariatgorji, Mohammadreza; Nilsson, Anna; Goodwin, Richard J A; Källback, Patrik et al.

Ingår i Neuron, s. 697-707, 2014

• DOI för Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and L-DOPA-induced dyskinesia

Bourdenx, Mathieu; Nilsson, Anna; Wadensten, Henrik; Fälth, Maria et al.

Ingår i Neurobiology of Disease, s. 307-312, 2014

• DOI för Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and L-DOPA-induced dyskinesia

Mass Spectrometry Imaging of Cassette-Dosed Drugs for Higher Throughput Pharmacokinetic and Biodistribution Analysis

Swales, John G.; Tucker, James W.; Strittmatter, Nicole; Nilsson, Anna et al.

Ingår i Analytical Chemistry, s. 8473-8480, 2014

• DOI för Mass Spectrometry Imaging of Cassette-Dosed Drugs for Higher Throughput Pharmacokinetic and Biodistribution Analysis

Neurotoxin-Induced Neuropeptide Perturbations in Striatum of Neonatal Rats

Karlsson, Oskar; Kultima, Kim; Wadensten, Henrik; Nilsson, Anna et al.

Ingår i Journal of Proteome Research, s. 1678-1690, 2013

• DOI för Neurotoxin-Induced Neuropeptide Perturbations in Striatum of Neonatal Rats

Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium

Nilsson, Carol L.; Berven, Frode; Selheim, Frode; Liu, Huiling et al.

Ingår i Journal of Proteome Research, s. 134-149, 2013

• DOI för Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium

Chronic Nicotine Treatment Impacts the Regulation of Opioid and Non-opioid Peptides in the Rat Dorsal Striatum

Petruzziello, Filomena; Falasca, Sara; Andrén, Per E.; Rainer, Gregor et al.

Ingår i Molecular & Cellular Proteomics, s. 1553-1562, 2013

• DOI för Chronic Nicotine Treatment Impacts the Regulation of Opioid and Non-opioid Peptides in the Rat Dorsal Striatum

Evaluation of Database Search Programs for Accurate Detection of Neuropeptides in Tandem Mass Spectrometry Experiments

Akhtar, Malik N.; Southey, Bruce R.; Andrén, Per E.; Sweedler, Jonathan V. et al.

Ingår i Journal of Proteome Research, s. 6044-6055, 2012

• DOI för Evaluation of Database Search Programs for Accurate Detection of Neuropeptides in Tandem Mass Spectrometry Experiments

In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies

Nilsson, Anna; Forngren, B.; Bjurström, S.; Goodwin, R. J. A. et al.

Ingår i PLOS ONE, 2012

• DOI för In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies
• Ladda ner fulltext (pdf) av In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies

The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging

Goodwin, Richard JA; Iverson, Suzanne L; Andrén, Per E

Ingår i Rapid Communications in Mass Spectrometry, s. 494-498, 2012

• DOI för The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging

Extensive Characterization of Tupaia belangeri Neuropeptidome Using an Integrated Mass Spectrometric Approach

Petruzziello, Filomena; Fouillen, Laetitia; Wadensten, Henrik; Kretz, Robert et al.

Ingår i Journal of Proteome Research, s. 886-896, 2012

• DOI för Extensive Characterization of Tupaia belangeri Neuropeptidome Using an Integrated Mass Spectrometric Approach

Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects

Nilsson, Anna; Stroth, Nikolas; Zhang, Xiaoqun; Qi, Hongshi et al.

Ingår i Neuropharmacology, s. 347-357, 2012

• DOI för Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects

Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation

Goodwin, Richard J. A.; Nilsson, Anna; Borg, Daniel; Langridge-Smith, Pat R. R. et al.

Ingår i Journal of Proteomics, s. 4912-4920, 2012

• DOI för Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation

Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections

Källback, Patrik; Shariatgorji, Mohammadreza; Nilsson, Anna; Andrén, Per E.

Ingår i Journal of Proteomics, s. 4941-4951, 2012

• DOI för Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections

Deuterated Matrix-Assisted Laser Desorption Ionization Matrix Uncovers Masked Mass Spectrometry Imaging Signals of Small Molecules

Shariatgorji, Mohammadreza; Nilsson, Anna; Goodwin, Richard J. A.; Svenningsson, Per et al.

Ingår i Analytical Chemistry, s. 7152-7157, 2012

• DOI för Deuterated Matrix-Assisted Laser Desorption Ionization Matrix Uncovers Masked Mass Spectrometry Imaging Signals of Small Molecules

Controlled-pH Tissue Cleanup Protocol for Signal Enhancement of Small Molecule Drugs Analyzed by MALDI-MS Imaging

Shariatgorji, Mohammadreza; Källback, Patrik; Gustavsson, Lena; Schintu, Nicoletta et al.

Ingår i Analytical Chemistry, s. 4603-4607, 2012

• DOI för Controlled-pH Tissue Cleanup Protocol for Signal Enhancement of Small Molecule Drugs Analyzed by MALDI-MS Imaging

High Identification Rates of Endogenous Neuropeptides from Mouse Brain

Zhang, Xiaozhe; Petruzziello, Filomena; Zani, Fabio; Fouillen, Laetitia et al.

Ingår i Journal of Proteome Research, s. 2819-2827, 2012

• DOI för High Identification Rates of Endogenous Neuropeptides from Mouse Brain

High Speed Data Processing for Imaging MS-Based Molecular Histology Using Graphical Processing Units

Jones, Emrys A.; van Zeijl, Rene J. M.; Andrén, Per E.; Deelder, Andre M. et al.

Ingår i Journal of the American Society for Mass Spectrometry, s. 745-752, 2012

• DOI för High Speed Data Processing for Imaging MS-Based Molecular Histology Using Graphical Processing Units

Imaging mass spectrometry: a user’s guide to a new technique for biological and biomedical research

McDonnell, L; Andren, Per E; Corthals, GL

Ingår i Journal of Proteomics, s. 4881-4882, 2012

• DOI för Imaging mass spectrometry: a user’s guide to a new technique for biological and biomedical research

Identification of protein-protein interactions by surface plasmon resonance followed by mass spectrometry

Madeira, Alexandra; Vikeved, Elisabet; Nilsson, Anna; Sjögren, Benita et al.

Ingår i Current protocols in protein science, 2011

• DOI för Identification of protein-protein interactions by surface plasmon resonance followed by mass spectrometry

Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression

Madeira, Alexandra; Yang, Junfeng; Zhang, Xiaoqun; Vikeved, Elisabet et al.

Ingår i Neurochemistry International, s. 280-289, 2011

• DOI för Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression

Neuropeptide profiling of the bovine hypothalamus: Thermal stabilization is an effective tool in inhibiting post-mortem degradation

Colgrave, Michelle L.; Xi, Li; Lehnert, Sigrid A.; Flatscher-Bader, Traute et al.

Ingår i Proteomics, s. 1264-1276, 2011

• DOI för Neuropeptide profiling of the bovine hypothalamus: Thermal stabilization is an effective tool in inhibiting post-mortem degradation

Distribution, Level, Pharmacology, Regulation, and Signaling of 5-HT6 Receptors in Rats and Marmosets With Special Reference to an Experimental Model of Parkinsonism

Zhang, Xiaoqun; Andrén, Per E.; Glennon, Richard A.; Svenningsson, Per

Ingår i Journal of Comparative Neurology, s. 1815-1827, 2011

• DOI för Distribution, Level, Pharmacology, Regulation, and Signaling of 5-HT6 Receptors in Rats and Marmosets With Special Reference to an Experimental Model of Parkinsonism

Qualitative and Quantitative MALDI Imaging of the Positron Emission Tomography Ligands Raclopride (a D2 Dopamine Antagonist) and SCH 23390 (a D1 Dopamine Antagonist) in Rat Brain Tissue Sections Using a Solvent-Free Dry Matrix Application Method

Goodwin, Richard J A; Mackay, C Logan; Nilsson, Anna; Harrison, David J et al.

Ingår i Analytical Chemistry, s. 9694-9701, 2011

• DOI för Qualitative and Quantitative MALDI Imaging of the Positron Emission Tomography Ligands Raclopride (a D2 Dopamine Antagonist) and SCH 23390 (a D1 Dopamine Antagonist) in Rat Brain Tissue Sections Using a Solvent-Free Dry Matrix Application Method

Neuropeptidomic analysis of the embryonic Japanese quail diencephalon

Scholz, Birger; Alm, Henrik; Mattsson, Anna; Nilsson, Anna et al.

Ingår i BMC Developmental Biology, s. 30, 2010

• DOI för Neuropeptidomic analysis of the embryonic Japanese quail diencephalon

In vivo investigation of brain and systemic ketobemidone metabolism

Sundström, Ingela; Arts, Joris; Westerlund, Douglas; Andrén, Per E.

Ingår i The Analyst, s. 405-413, 2010

• DOI för In vivo investigation of brain and systemic ketobemidone metabolism

In Vitro Neurotoxicity of PBDE-99: Immediate and Concentration-Dependent Effects on Protein Expression in Cerebral Cortex Cells

Alm, Henrik; Scholz, Birger; Kultima, Kim; Nilsson, Anna et al.

Ingår i Journal of Proteome Research, s. 1226-1235, 2010

• DOI för In Vitro Neurotoxicity of PBDE-99: Immediate and Concentration-Dependent Effects on Protein Expression in Cerebral Cortex Cells

Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry

Vegvari, Akos; Fehniger, Thomas E.; Gustavsson, Lena; Nilsson, Anna et al.

Ingår i Journal of Proteomics, s. 1270-1278, 2010

• DOI för Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry

Fine Mapping the Spatial Distribution and Concentration of Unlabeled Drugs within Tissue Micro-Compartments Using Imaging Mass Spectrometry

Nilsson, Anna; Fehniger, Thomas E.; Gustavsson, Lena; Andersson, Malin et al.

Ingår i PloS one, 2010

• DOI för Fine Mapping the Spatial Distribution and Concentration of Unlabeled Drugs within Tissue Micro-Compartments Using Imaging Mass Spectrometry

Proteomic profiling of the Baltic Sea cyanobacterium Nodularia spumigena strain AV1 during ammonium supplementation

Vintila, Simina; Jonasson, Sara; Wadensten, Henrik; Nilsson, Anna et al.

Ingår i Journal of Proteomics, s. 1670-1679, 2010

• DOI för Proteomic profiling of the Baltic Sea cyanobacterium Nodularia spumigena strain AV1 during ammonium supplementation

Development and evaluation of normalization methods for label-free relative quantification of endogenous peptides

Kultima, Kim; Nilsson, Anna; Scholz, Birger; Rossbach, Uwe L. et al.

Ingår i Molecular & Cellular Proteomics, s. 2285-2295, 2009

• DOI för Development and evaluation of normalization methods for label-free relative quantification of endogenous peptides

Heat stabilization of the tissue proteome: a new technology for improved proteomics

Svensson, Marcus; Boren, Mats; Skold, Karl; Fälth, Maria et al.

Ingår i Journal of Proteome Research, s. 974-981, 2009

• DOI för Heat stabilization of the tissue proteome: a new technology for improved proteomics

Striatal alterations of secretogranin-1, somatostatin, prodynorphin and cholecystokinin peptides in an experimental mouse model of Parkinson’s disease

Nilsson, Anna; Fälth, Maria; Zhang, Xiaoqun; Kultima, Kim et al.

Ingår i Molecular & Cellular Proteomics, s. 1094-1104, 2009

• DOI för Striatal alterations of secretogranin-1, somatostatin, prodynorphin and cholecystokinin peptides in an experimental mouse model of Parkinson’s disease

Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions

Madeira, Alexandra; Öhman, Elisabet; Nilsson, Anna; Sjögren, Benita et al.

Ingår i Nature Protocols, s. 1023-1037, 2009

• DOI för Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions

A quantitative peptidomic analysis of peptides related to the endogenous opioid and tachykinin systems in nucleus accumbens of rats following naloxone-precipitated morphine withdrawal

Rossbach, Uwe; Nilsson, Anna; Fälth, Maria; Kultima, Kim et al.

Ingår i Journal of Proteome Research, s. 1091-1098, 2009

• DOI för A quantitative peptidomic analysis of peptides related to the endogenous opioid and tachykinin systems in nucleus accumbens of rats following naloxone-precipitated morphine withdrawal

Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism

Zhang, Xiaoqun; Andren, Per E; Greengard, Paul; Svenningsson, Per

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 2163-2168, 2008

• DOI för Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism

Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex

Alm, Henrik; Kultima, Kim; Scholz, Birger; Nilsson, Anna et al.

Ingår i Neurotoxicology, s. 628-637, 2008

• DOI för Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex

Use of Surface Plasmon Resonance Coupled with Mass Spectrometry Reveals an Interaction between the Voltage-Gated Sodium Channel Type X alpha-Subunit and Caveolin-1

Öhman, Elisabet; Nilsson, Anna; Madeira, Alexandra; Sjögren, Benita et al.

Ingår i Journal of Proteome Research, s. 5333-5338, 2008

• DOI för Use of Surface Plasmon Resonance Coupled with Mass Spectrometry Reveals an Interaction between the Voltage-Gated Sodium Channel Type X alpha-Subunit and Caveolin-1

Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure

Scholz, Birger; Svensson, Marcus; Alm, Henrik; Sköld, Karl et al.

Ingår i PLoS ONE, 2008

• DOI för Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure

Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease

Zhang, Xiaoqun; Andren, Per E; Chergui, Karima; Svenningsson, Per

Ingår i Neuropharmacology, s. 1143-1152, 2008

• DOI för Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease

Validation of endogenous peptide identifications using a database of tandem mass spectra

Fälth, Maria; Svensson, Marcus; Nilsson, Anna; Sköld, Karl et al.

Ingår i Journal of Proteome Research, s. 3049-3053, 2008

• DOI för Validation of endogenous peptide identifications using a database of tandem mass spectra

Analytical utility of small neutral losses from reduced species in electron capture dissociation studied using SwedECD database

Fälth, Maria; Savitski, Mikhail M; Nielsen, Michael L; Kjeldsen, Frank et al.

Ingår i Analytical Chemistry, s. 8089-8094, 2008

• DOI för Analytical utility of small neutral losses from reduced species in electron capture dissociation studied using SwedECD database

Method development for identification of ketobemidone metabolites in microdialysate samples by coupled-column capillary liquid chromatography-tandem mass spectrometry

Sundström, Ingela; Andrén, Per E; Westerlund, Douglas

Ingår i Journal of Chromatography A, s. 503-513, 2008

• DOI för Method development for identification of ketobemidone metabolites in microdialysate samples by coupled-column capillary liquid chromatography-tandem mass spectrometry

SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides

Fälth, Maria; Savitski, Mikhail M.; Nielsen, Michael L.; Kjeldsen, Frank et al.

Ingår i Journal of Proteome Research, s. 4063-4067, 2007

• DOI för SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides

Neuropeptidomics: MS applied to the discovery of novel peptides from the brain

Svensson, Marcus; Sköld, Karl; Nilsson, Anna; Fälth, Maria et al.

Ingår i Analytical Chemistry, s. 14-21, 2007

• DOI för Neuropeptidomics: MS applied to the discovery of novel peptides from the brain

Neuropeptidomics: expanding proteomics downwards.

Svensson, Marcus; Sköld, Karl; Nilsson, Anna; Fälth, Maria et al.

Ingår i Biochemical Society Transactions, s. 588-593, 2007

• DOI för Neuropeptidomics: expanding proteomics downwards.

Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model

Zhang, Xiaoqun; Andrén, Per E.; Svenningsson, Per

Ingår i Physiology and Behavior, s. 29-33, 2007

• DOI för Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model

In vitro imaging techniques in neurodegenerative diseases

Långström, Bengt; Andrèn, Per E; Lindhe, Örjan; Svedberg, Marie et al.

Ingår i Molecular Imaging and Biology, s. 161-175, 2007

• DOI för In vitro imaging techniques in neurodegenerative diseases

Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson’s Disease and identification of FKBP-12-binding proteins

Nilsson, Anna; Sköld, Karl; Sjögren, Benita; Svensson, Marcus et al.

Ingår i Journal of Proteome Research, s. 3952-3961, 2007

• DOI för Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson’s Disease and identification of FKBP-12-binding proteins

Neuropeptidomics strategies for specific and sensitive identification of endogenous peptides

Fälth, Maria; Sköld, Karl; Svensson, Marcus; Nilsson, Anna et al.

Ingår i Molecular & Cellular Proteomics, s. 1188-1197, 2007

• DOI för Neuropeptidomics strategies for specific and sensitive identification of endogenous peptides

An Automated Method for Scanning LC−MS Data Sets for Significant Peptides and Proteins, Including Quantitative Profiling and Interactive Confirmation: An Automated Method for Scanning LC−MS Data Sets for Significant Peptides and Proteins, Including Quantitative Profiling and Interactive Confirmation

Kaplan, Anders; Söderström, Malin; Fenyö, David; Nilsson, Anna et al.

Ingår i Journal of Proteome Research, s. 2888-2895, 2007

• DOI för An Automated Method for Scanning LC−MS Data Sets for Significant Peptides and Proteins, Including Quantitative Profiling and Interactive Confirmation: An Automated Method for Scanning LC−MS Data Sets for Significant Peptides and Proteins, Including Quantitative Profiling and Interactive Confirmation

The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: Stathmin (2-20) and peptides as sample quality indicators.

Sköld, Karl; Svensson, Marcus; Norrman, Mathias; Sjögren, Benita et al.

Ingår i Proteomics, s. 4445-4456, 2007

• DOI för The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: Stathmin (2-20) and peptides as sample quality indicators.

Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGE

Kultima, Kim; Scholz, Birger; Alm, Henrik; Sköld, Karl et al.

Ingår i BMC Bioinformatics, s. 475, 2006

• DOI för Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGE

Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

Zhang, Xiaoqun; Andrén, Per E.; Svenningsson, Per

Ingår i Brain Research, s. 207-210, 2006

• DOI för Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

SwePep, a database designed for endogenous peptides and mass spectrometry

Fälth, Maria; Sköld, Karl; Norrman, Mathias; Svensson, Marcus et al.

Ingår i Molecular & Cellular Proteomics, s. 998-1005, 2006

• DOI för SwePep, a database designed for endogenous peptides and mass spectrometry

SwePep – A database designed for endogenous peptides and mass spectrometry

Fälth, Maria; Sköld, Karl; Norrman, Mathias; Svensson, Marcus et al.

Ingår i Molecular & Cellular Proteomics, s. 998-1005, 2006

• DOI för SwePep – A database designed for endogenous peptides and mass spectrometry

Decreased Striatal Levels of PEP-19 Following MPTP Lesion in the Mouse.

Sköld, Karl; Svensson, Marcus; Nilsson, Anna; Zhang, Xiaqun et al.

Ingår i J Proteome Res, s. 262-269, 2006

Electrokinetic-driven microfluidic system in poly(dimethylsiloxane) for mass spectrometry detection integrating sample injection, capillary electrophoresis, and electrospray emitter on-chip

Thorslund, Sara; Lindberg, Peter; Andrén, Per E.; Nikolajeff, Fredrik et al.

Ingår i Electrophoresis, s. 4674-4683, 2005

• DOI för Electrokinetic-driven microfluidic system in poly(dimethylsiloxane) for mass spectrometry detection integrating sample injection, capillary electrophoresis, and electrospray emitter on-chip

Electrokinetic-driven microfluidic system in poly(dimethylsiloxane) for mass spectrometry detection integrating sample injection, capillary electrophoresis, and electrospray emitter on-chip

Thorslund, Sara; Lindberg, Peter; Andrén, Per E; Nikolajeff, Fredrik et al.

Ingår i Electrophoresis, s. 4674-4683, 2005

• DOI för Electrokinetic-driven microfluidic system in poly(dimethylsiloxane) for mass spectrometry detection integrating sample injection, capillary electrophoresis, and electrospray emitter on-chip

Poly(dimethylsiloxane)-Based Microchip for Two-Dimensional Solid-Phase Extraction-Capillary Electrophoresis with an Integrated Electrospray Emitter Tip

Dahlin, Andreas P.; Bergström, Sara K.; Andrén, Per E.; Markides, Karin E. et al.

Ingår i Analytical Chemistry, s. 5356-5363, 2005

• DOI för Poly(dimethylsiloxane)-Based Microchip for Two-Dimensional Solid-Phase Extraction-Capillary Electrophoresis with an Integrated Electrospray Emitter Tip

Increased Levels of Ubiquitin in the 6-OHDA-Lesioned Striatum of Rats

Pierson, Johan; Svenningsson, Per; Caprioli, Richard M.; Andrén, Per E.

Ingår i Journal of Proteome Research, s. 223-226, 2005

• DOI för Increased Levels of Ubiquitin in the 6-OHDA-Lesioned Striatum of Rats

Capillary electrophoresis coupled to mass spectrometry from a polymer modified poly(dimethylsiloxane) microchip with an integrated graphite electrospray tip

Pettersson Dahlin, Andreas; Wetterhall, Magnus; Liljegren, Gustav; Bergström, Sara K. et al.

Ingår i The Analyst, s. 193-199, 2005

• DOI för Capillary electrophoresis coupled to mass spectrometry from a polymer modified poly(dimethylsiloxane) microchip with an integrated graphite electrospray tip

Peptidomics-based discovery of novel neuropeptides.

Svensson, Marcus; Sköld, Karl; Svenningsson, Per; Andren, Per E

Ingår i J Proteome Res, s. 213-9, 2003

Purification and characterization of substance P endopeptidase activities in the rat spinal cord

Karlsson, K; Eriksson, U; Andren, P; Nyberg, F

Ingår i PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, s. 59-78, 1997

Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics

Baijnath, Sooraj; Kaya, Ibrahim; Nilsson, Anna; Shariatgorji, Reza et al.

Ingår i TIPS - Trends in Pharmacological Sciences, s. 740-753, 2022

• DOI för Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics
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Future technology insight: mass spectrometry imaging as a tool in drug research and development

Cobice, D. F.; Goodwin, R. J. A.; Andrén, Per E.; Nilsson, Anna et al.

Ingår i British Journal of Pharmacology, s. 3266-3283, 2015

• DOI för Future technology insight: mass spectrometry imaging as a tool in drug research and development

Association of chromosome 19 to lung cancer genotypes and phenotypes

Wang, Xiangdong; Zhang, Yong; Nilsson, Carol L.; Berven, Frode S. et al.

Ingår i Cancer Metastasis Review, s. 217-226, 2015

• DOI för Association of chromosome 19 to lung cancer genotypes and phenotypes

Mass Spectrometry Imaging in Drug Development

Nilsson, Anna; Goodwin, Richard J. A.; Shariatgorji, Mohammadreza; Vallianatou, Theodosia et al.

Ingår i Analytical Chemistry, s. 1437-1455, 2015

• DOI för Mass Spectrometry Imaging in Drug Development

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

Shariatgorji, Mohammadreza; Svenningsson, Per; Andrén, Per E.

Ingår i Neuropsychopharmacology, s. 34-49, 2014

• DOI för Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

Developments in biobanking workflow standardization providing sample integrity and stability

Malm, Johan; Fehniger, Thomas E.; Danmyr, Pia; Vegvari, Akos et al.

Ingår i Journal of Proteomics, s. 38-45, 2013

• DOI för Developments in biobanking workflow standardization providing sample integrity and stability

Going forward: Increasing the accessibility of imaging mass spectrometry

McDonnell, Liam A.; Heeren, Ron M. A.; Andrén, Per E.; Stoeckli, Markus et al.

Ingår i Journal of Proteomics, s. 5113-5121, 2012

• DOI för Going forward: Increasing the accessibility of imaging mass spectrometry

MALDI mass spectrometry imaging of dopamine and PET D1 and D2 receptor ligands in rodent brain tissues

Goodwin, R. J. A.; Shariatgorji, Mohammadreza; Andren, Per E.

Ingår i Dopamine Receptor Technologies, s. 177-196, Springer-Verlag New York, 2015

• DOI för MALDI mass spectrometry imaging of dopamine and PET D1 and D2 receptor ligands in rodent brain tissues

Peptidomics-based Discovery of Endogenous Neuropeptides in the Brain

Andren, Per; Svensson, Marcus; Skold, Karl; Svenningsson, Per

Ingår i Emerging Technologies in Protein and Genomic Material, s. 155-167, Elsevier Science B.V, Amsterdam, 2003

Imaging age-induced perturbations of mitochondrial function, neurotransmission and lipid signaling in specific brain regions

Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna; Karlgren, Maria et al.

Imaging aging effects on the catecholamine, serotonin, and histamine neurotransmitter systems in specific brain regions

Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Mohammadreza; Nilsson, Anna et al.

Mass spectrometry imaging of multiple basal ganglia neuropeptides shows abnormal neuropeptide processing associated with L-DOPA-induced dyskinesia in a primate model of Parkinson’s disease

Hulme, Heather; Fridjonsdottir, Elva; Vallianatou, Theodosia; Shariatgorji, Mohammadreza et al.

Mass spectrometry imaging visualizes region-specific neurotransmitter alterations of rat decision-making strategies

Tjernström, Nikita; Luptakova, Dominika; Nilsson, Anna; Shariatgorji, Reza et al.

Rapid metabolic profiling of one microliter crude CSF by MALDI MS can differentiate de novo Parkinson’s disease

Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik; Shariatgorji, Reza et al.

POMC-specific Modulation of Metabolic and Immune Pathways via Melanocortin-3 Receptor Signaling

Nezhyva, Mariya; Sandbaumhüter, Friederike A.; Andrén, Per E.; Jansson, Erik T.

Mass spectrometry imaging reveals brain-region specific changes in metabolism and acetylcholine levels in experimental Parkinson’s disease and L-DOPA-induced dyskinesia

Fridjonsdottir, Elva; Vallianatou, Theodosia; Aerts, Jordan T.; Mantas, Ioannis et al.