Pär Gerwins

Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation-A Case Report

Winberg, Hans; Gerwins, Pär; Hagelsteen, Kristine

Ingår i EUROPEAN JOURNAL OF PEDIATRIC SURGERY REPORTS, 2024

• DOI för Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation-A Case Report
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Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment

Pavlovic, Natasa; Kopsida, Maria; Gerwins, Pär; Heindryckx, Femke

Ingår i Life Sciences, 2021

• DOI för Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment
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Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype

Pavlović, Natasa; Kopsida, Maria; Gerwins, Pär; Heindryckx, Femke

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype
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Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

Pavlovic, Natasa; Calitz, Carlemi; Thanapirom, Kess; Mazza, Guiseppe et al.

Ingår i eLIFE, 2020

• DOI för Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma
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Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment

Öhman Fuchs, Peder; Calitz, Carlemi; Pavlovic, Natasa; Binet, Francois et al.

Ingår i Cellular Signalling, 2020

• DOI för Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment
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Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation-A Case Report

Winberg, Hans; Gerwins, Pär; Hagelsteen, Kristine

Ingår i EUROPEAN JOURNAL OF PEDIATRIC SURGERY REPORTS, 2024

• DOI för Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation-A Case Report
• Ladda ner fulltext (pdf) av Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation-A Case Report

Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment

Pavlovic, Natasa; Kopsida, Maria; Gerwins, Pär; Heindryckx, Femke

Ingår i Life Sciences, 2021

• DOI för Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment
• Ladda ner fulltext (pdf) av Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment

Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype

Pavlović, Natasa; Kopsida, Maria; Gerwins, Pär; Heindryckx, Femke

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype
• Ladda ner fulltext (pdf) av Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype

Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

Pavlovic, Natasa; Calitz, Carlemi; Thanapirom, Kess; Mazza, Guiseppe et al.

Ingår i eLIFE, 2020

• DOI för Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma
• Ladda ner fulltext (pdf) av Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment

Öhman Fuchs, Peder; Calitz, Carlemi; Pavlovic, Natasa; Binet, Francois et al.

Ingår i Cellular Signalling, 2020

• DOI för Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment
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FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

Heldin, Johan; O'Callaghan, Paul; Hernández Vera, Rodrigo; Fredlund Fuchs, Peder et al.

Ingår i Cellular Signalling, s. 125-132, 2017

• DOI för FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing

Heindryckx, Femke; Binet, Francois; Ponticos, Markella; Rombouts, Krista et al.

Ingår i EMBO Molecular Medicine, s. 729-744, 2016

• DOI för Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing
• Ladda ner fulltext (pdf) av Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing

Targeting the tumor stroma in hepatocellular carcinoma

Heindryckx, Femke; Gerwins, Pär

Ingår i World Journal of Hepatology, s. 165-176, 2015

• DOI för Targeting the tumor stroma in hepatocellular carcinoma

ER Stress Enhances Liver Fibrosis Through MIR-150 Degradation and XBP-1 Splicing

Heindryckx, Femke; Binet, F.; Kreuger, Johan; Gerwins, Pär

Ingår i Journal of Hepatology, 2015

Effect Of Extracellular Matrix On Cancer Stem Cells

Heindryckx, Femke; Rauer, D.; Bogaerts, E.; Gerwins, Pär et al.

Ingår i Journal of Hepatology, 2015

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Ingår i Blood, s. 2016-2026, 2015

• DOI för Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo

Strese, Sara; Wickström, Malin; Fuchs, Peder Fredlund; Fryknäs, Mårten et al.

Ingår i Biochemical Pharmacology, s. 888-895, 2013

• DOI för The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo

MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA)

Kasza, Zsolt; Fredlund Fuchs, Peder; Tamm, Christoffer; Eriksson, Anna S. et al.

Ingår i Journal of Biological Chemistry, s. 25956-25963, 2013

• DOI för MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA)

An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels

Kilarski, Witold W; Petersson, Ludvig; Fuchs, Peder Fredlund; Zielinski, Marcin S et al.

Ingår i Angiogenesis, s. 643-655, 2012

• DOI för An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels

Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Larsson, Erik; Fredlund Fuchs, Peder; Heldin, Johan; Barkefors, Irmeli et al.

Ingår i Genome Medicine, s. 108, 2009

• DOI för Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Biomechanical regulation of blood vessel growth during tissue vascularization

Kilarski, Witold W.; Samolov, Branka; Petersson, Ludvig; Kvanta, Anders et al.

Ingår i Nature Medicine, s. 657-664, 2009

• DOI för Biomechanical regulation of blood vessel growth during tissue vascularization

A new mechanism of blood vessel growth - hope for new treatment strategies

Kilarski, Witold W.; Gerwins, Pär

Ingår i Discovery medicine, s. 23-27, 2009

Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer

Rennel, Emma; Mellberg, Sofie; Dimberg, Anna; Petersson, Ludvig et al.

Ingår i Experimental Cell Research, s. 1285-1294, 2007

• DOI för Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer

Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection

Peng, Siwei; Larsson, Annika; Wassberg, Erik; Gerwins, Pär et al.

Ingår i Laboratory Investigation, s. 1195-1205, 2007

• DOI för Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection

Lactadherin binds to elastin -a starting point for medin amyloid formation?

Larsson, Annika; Peng, Siwei; Persson, Helena; Rosenbloom, Joel et al.

Ingår i Amyloid, s. 78-85, 2006

• DOI för Lactadherin binds to elastin -a starting point for medin amyloid formation?

An ex vivo model for functional studies of myofibroblasts

Kilarski, Witold W.; Jura, Natalia; Gerwins, Pär

Ingår i Laboratory Investigation, s. 643-54, 2005

• DOI för An ex vivo model for functional studies of myofibroblasts

Efficient human interferon-alpha gene transfer to neuroendocrine tumor cells with long-term and stable expression

Liu, Minghui; Kilarski, Witold W.; Gerwins, Pär; Öberg, Kjell et al.

Ingår i Neuroendocrinology, s. 264-73, 2005

• DOI för Efficient human interferon-alpha gene transfer to neuroendocrine tumor cells with long-term and stable expression

Src family kinase-inhibitor PP2 reduces focal ischemic brain injury

Lennmyr, Fredrik; Ericsson, A.; Gerwins, Pär; Akterin, S. et al.

Ingår i Acta Neurologica Scandinavica, s. 175-9, 2004

• DOI för Src family kinase-inhibitor PP2 reduces focal ischemic brain injury

Increased brain injury and vascular leakage after pretreatment with p38-inhibitor SB203580 in transient ischemia

Lennmyr, Fredrik; Ericsson, A.; Gerwins, Pär; Ahlström, Håkan et al.

Ingår i Acta Neurologica Scandinavica, s. 339-45, 2003

• DOI för Increased brain injury and vascular leakage after pretreatment with p38-inhibitor SB203580 in transient ischemia

Regulation of endothelial cell differentiation and transformation by H-Ras

Rennel, Emma; Cross, Michael J.; Klint, Peter; Bai, Xianhe et al.

Ingår i Experimental Cell Research, s. 189-200, 2003

• DOI för Regulation of endothelial cell differentiation and transformation by H-Ras

Inactivation of Src family kinases inhibits angiogenesis in vivo. Implications for a mechanism involving organization of the actin cytoskeleton

Kilarski, Witold; Jura, Natalia; Gerwins, Pär

Ingår i Experimental Cell Research, s. 70-82, 2003

p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

Matsumoto, Taro; Turesson, Ingela; Book, Majlis; Gerwins, Pär et al.

Ingår i Journal of Cell Biology, s. 149-160, 2002

• DOI för p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

Activation of mitogen-activated protein kinases in experimental cerebral ischemia

Lennmyr, Fredrik; Karlsson, S.; Gerwins, Pär; Ata, K. A. et al.

Ingår i Acta Neurologica Scandinavica, s. 333-40, 2002

• DOI för Activation of mitogen-activated protein kinases in experimental cerebral ischemia

How to make tetracycline-regulated transgene expression go on and off

Rennel, Emma; Gerwins, Pär

Ingår i Analytical Biochemistry, s. 79-84, 2002

• DOI för How to make tetracycline-regulated transgene expression go on and off

Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes

Sakata, Naoki; Hamelmann, Eckhard; Siadak, Anthony W.; Terada, Naohiro et al.

Ingår i Cellular Immunology, s. 109-123, 2000

• DOI för Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes

Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis

Gerwins, Pär; Sköldenberg, E; Claesson-Welsh, Lena

Ingår i Critical reviews in oncology/hematology, s. 185-194, 2000

Differential activation and regulation of mitogen activated protein kinases through the antigen receptor and CD40 in human B cells

Sakata, Naoki; Kawasome, Hideki; Terada, Naohiro; Gerwins, Pär et al.

Ingår i European Journal of Immunology, s. 2999-3008, 1999

• DOI för Differential activation and regulation of mitogen activated protein kinases through the antigen receptor and CD40 in human B cells

Platelets as Key Factors in Hepatocellular Carcinoma

Pavlovic, Natasa; Rani, Bhavna; Gerwins, Pär; Heindryckx, Femke

Ingår i Cancers, 2019

• DOI för Platelets as Key Factors in Hepatocellular Carcinoma
• Ladda ner fulltext (pdf) av Platelets as Key Factors in Hepatocellular Carcinoma

Anti-Vascular endothelial growth factor-based angiostatics

Gerwins, Pär; Claesson-Welsh, Lena

Ingår i Encyclopedia of Cancer, s. 135, Elsevier, 2002

A quantitative neovascularization assay for screening pro- and anti-angiogenic factors

Kilarski, Witold; Petersson, Ludvig; Gerwins, Pär

The role of growth factor receptor signaling for angiogenesis and vessel stability in an experimental wound healing model

Petersson, Ludvig; Fredlund Fuchs, Peder; Kilarski, Witold; Gerwins, Pär

Identification of VEGF-A-induced genes in human microvascular endothelial cells using an in vitro model of invasive angiogenesis

Rennel, Emma; Mellberg, Sofie; Ameur, Adam; Orzechowski Westholm, Jakub et al.

VEGF-A-mediated gene expression in differentiating human microvascular endothelial cells

Mellberg, Sofie; Rennel, Emma; Dimberg, Anna; Bohman, Svante et al.

Neovascularization is directed by tensile forces generated during tissue remodelling

Kilarski, Witold; Samolov, Branka; Kvanta, Anders; Gerwins, Pär

A quantitative in vivo avian neovascularization assay that allows live monitoring of neovascularization processes

Kilarski, Witold; Gerwins, Pär

Medin and medin-amyloid in thoracic aortic aneurysm and dissection

Peng, Siwei; Wassberg, Erik; Gerwins, Pär; Thelin, Stefan et al.

FGD5 promotes VEGF-A signaling via inhibition of VEGF-receptor ubiquitination and degradation

Heldin, Johan; Fredlund Fuchs *, Peder; O’Callaghan *, Paul; Kasza, Zsolt et al.