Ulrika Rosenström

Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir M. et al.

Ingår i European Journal of Pharmaceutical Sciences, 2025

• DOI för Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics
• Ladda ner fulltext (pdf) av Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir M. et al.

Ingår i ACS Pharmacology & Translational Science, s. 3600-3612, 2025

• DOI för Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m
• Ladda ner fulltext (pdf) av Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Olaniran Håkansson, Esther; Zelepukin, Ivan V.; Obeid, Karim; Bitzios, Athanasios et al.

Ingår i EJNMMI Research, 2025

• DOI för A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression
• Ladda ner fulltext (pdf) av A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika et al.

Ingår i ACS Omega, s. 18608-18616, 2024

• DOI för Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
• Ladda ner fulltext (pdf) av Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir M. et al.

Ingår i European Journal of Pharmaceutical Sciences, 2025

• DOI för Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics
• Ladda ner fulltext (pdf) av Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir M. et al.

Ingår i ACS Pharmacology & Translational Science, s. 3600-3612, 2025

• DOI för Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m
• Ladda ner fulltext (pdf) av Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Olaniran Håkansson, Esther; Zelepukin, Ivan V.; Obeid, Karim; Bitzios, Athanasios et al.

Ingår i EJNMMI Research, 2025

• DOI för A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression
• Ladda ner fulltext (pdf) av A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika et al.

Ingår i ACS Omega, s. 18608-18616, 2024

• DOI för Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
• Ladda ner fulltext (pdf) av Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
• Ladda ner fulltext (pdf) av Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m

Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Engen, Karin; Lundbäck, Thomas; Yadav, Anubha; Puthiyaparambath, Sharathna et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation
• Ladda ner fulltext (pdf) av Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Ingår i Molecular Medicine Reports, 2024

• DOI för Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
• Ladda ner fulltext (pdf) av Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Ingår i Cancers, 2023

• DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
• Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

Abouzayed, Ayman; Seitova, Kamila; Lundmark, Fanny; Bodenko, Vitalina et al.

Ingår i Frontiers in Oncology, 2023

• DOI för ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
• Ladda ner fulltext (pdf) av ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Larkina, Mariia et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
• Ladda ner fulltext (pdf) av Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Ingår i Pharmaceutics, 2022

• DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
• Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Ingår i Nuclear Medicine and Biology, s. 54-62, 2021

• DOI för Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1
• Ladda ner fulltext (pdf) av Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Velikyan, Irina; Rosenström, Ulrika; Rosestedt, Maria; Eriksson, Olof et al.

Ingår i Pharmaceuticals, 2021

• DOI för Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
• Ladda ner fulltext (pdf) av Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2020

• DOI för Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model
• Ladda ner fulltext (pdf) av Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Ingår i ChemistryOpen, s. 325-337, 2020

• DOI för Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors
• Ladda ner fulltext (pdf) av Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2019

• DOI för Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer
• Ladda ner fulltext (pdf) av Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Oroujeni, Maryam; Abouzayed, Ayman; Lundmark, Fanny; Mitran, Bogdan et al.

Ingår i Pharmaceutics, 2019

• DOI för Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart
• Ladda ner fulltext (pdf) av Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

Mitran, Bogdan; Thisgaard, Helge; Rinne, Sara S.; Dam, Johan Hygum et al.

Ingår i Scientific Reports, 2019

• DOI för Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26
• Ladda ner fulltext (pdf) av Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

Ingår i Cancers, 2019

• DOI för Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
• Ladda ner fulltext (pdf) av Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

Ingår i International Journal of Cancer, s. 3347-3358, 2019

• DOI för Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26
• Ladda ner fulltext (pdf) av Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET

Monazzam, Azita; Lau, Joey; Velikyan, Irina; Li, Su-Chen et al.

Ingår i Scientific Reports, 2018

• DOI för Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET
• Ladda ner fulltext (pdf) av Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET

Selection of optimal macrocyclic chelator for high contrast PET imaging of gastrin releasing peptide receptor using cobalt-labeled bombesin antagonist RM26

Mitran, Bogdan; Thisgaard, H.; Rinne, Sara S.; Rosenström, Ulrika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

GRPR-targeted radiotherapy using the Lu-177-labeled GRPR-antagonist DOTAGA-PEG(2)-RM26

Mitran, Bogdan; Rinne, Sara S.; Azamy, F.; Vorobyeva, Anzhelika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26

Mitran, Bogdan; Thisgaard, Helge; Rosenström, Ulrika; Dam, Johan Hygum et al.

Ingår i Contrast Media & Molecular Imaging, 2017

• DOI för High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26
• Ladda ner fulltext (pdf) av High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26

GRPR-Targeted Radiotherapy: Influence of Chelator on Labeling and Biodistribution of Four Lu-177-Labeled Analogues of the GRPR-Antagonist PEG2-RM26

Orlova, Anna; Mitran, Bogdan; Maina, T.; Nock, B. A. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Eriksson, Olof; Rosenström, Ulrika; Selvaraju, Ram Kumar; Eriksson, Barbro et al.

Ingår i Acta Diabetologica, s. 1039-1045, 2017

• DOI för Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4
• Ladda ner fulltext (pdf) av Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Fully automated GMP production of [Ga-68]Ga-DO3A-VS-Cys(40)-Exendin-4 for clinical use

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof

Ingår i American Journal of Nuclear Medicine and Molecular Imaging, s. 111-125, 2017

• Ladda ner fulltext (pdf) av Fully automated GMP production of [Ga-68]Ga-DO3A-VS-Cys(40)-Exendin-4 for clinical use

Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Diwakarla, Shanti; Nylander, Erik; Grönbladh, Alfhild; Reddy Vanga, Sudarsana et al.

Ingår i Molecular Pharmacology, s. 413-424, 2016

• DOI för Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

Diwakarla, Shanti; Nylander, Erik; Grönbladh, Alfhild; Vanga, Sudarsana Reddy et al.

Ingår i ACS Chemical Neuroscience, s. 1383-1392, 2016

• DOI för Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

Feasibility of Multiple Examinations Using Ga-68-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry

Velikyan, Irina; Rosenström, Ulrika; Bulenga, Thomas N.; Eriksson, Olof et al.

Ingår i Pharmaceuticals, 2016

• DOI för Feasibility of Multiple Examinations Using Ga-68-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry
• Ladda ner fulltext (pdf) av Feasibility of Multiple Examinations Using Ga-68-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry

Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Mitran, Bogdan; Varasteh, Zohreh; Selvaraju, Ram Kumar; Lindeberg, Gunnar et al.

Ingår i International journal of oncology, s. 2124-2134, 2016

• DOI för Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Engen, Karin; Rosenström, Ulrika; Axelsson, Hanna; Konda, Vivek et al.

Ingår i Assay and drug development technologies, s. 180-193, 2016

• DOI för Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Ga-68/PET imaging and quantification of fibrosis using peptide-based tracers

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof; Antoni, Gunnar

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2016

Development of radiocobalt-labeled GRPR antagonist NOTA-PEG2-RM26.

Mitran, Bogdan; Varasteh, Zohreh; Rosenström, Ulrika; Tolmachev, Vladimir et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2015

Influence of chelators on targeting properties of In-111 and Ga-68 labeled GRPR antagonist

Orlova, Anna; Varasteh, Zohreh; Mitran, Bogdan; Rosestedt, Maria et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2015

The effect of macrocyclic chelators on the targeting properties of the ⁶⁸Ga-labeled gastrin releasing peptide receptor antagonist PEG₂-RM26

Varasteh, Zohreh; Mitran, Bogdan; Rosenström, Ulrika; Velikyan, Irina et al.

Ingår i Nuclear Medicine and Biology, s. 446-454, 2015

• DOI för The effect of macrocyclic chelators on the targeting properties of the ⁶⁸Ga-labeled gastrin releasing peptide receptor antagonist PEG₂-RM26

Rat organ distribution of [Lu-177]-DO3A-VS-Cys(40)-Exendin-4 for the estimation of human dosimetry: potential for radiotherapy

Velikyan, Irina; Bulenga, Thomas; Selvaraju, Ram Kumar; Lubberink, Mark et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2015

Extrapolated dosimetry of two novel Ga-68-labelled imaging agents for fibrosis: feasibility of multiple examinations

Velikyan, Irina; Rosenström, Ulrika; Bulenga, Thomas; Eriksson, Olof et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2015

The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin

Varasteh, Zohreh; Rosenström, Ulrika; Velikyan, Irina; Mitran, Bogdan et al.

Ingår i Molecules, s. 10455-10472, 2014

• DOI för The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin
• Ladda ner fulltext (pdf) av The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin

Nonresonant microwave heated continuous flow synthesis in medicinal chemistry

Engen, Karin; Sävmarker, Jonas; Lundback, Thomas; Wannberg, Johan et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2014

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Engen, Karin; Sävmarker, Jonas; Rosenström, Ulrika; Wannberg, Johan et al.

Ingår i Organic Process Research & Development, s. 1582-1588, 2014

• DOI för Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

Borhade, Sanjay R; Rosenström, Ulrika; Sävmarker, Jonas; Lundbäck, Thomas et al.

Ingår i ChemistryOpen, s. 256-263, 2014

• DOI för Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

Synthesis and preclinical evaluation of Ga-68-labeled collagelin analogs for imaging and quantification of fibrosis

Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio; Ljungvall, Ingrid et al.

Ingår i Nuclear Medicine and Biology, s. 728-736, 2014

• DOI för Synthesis and preclinical evaluation of Ga-68-labeled collagelin analogs for imaging and quantification of fibrosis

Influence of chelators on biodistribution and targeting properties of GRPR antagonist

Mitran, Bogdan; Varasteh, Zohreh; Rosestedt, Maria; Velikyan, Irina et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2014

Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic – targeting Mycobacterium tuberculosis ribonucleotide reductase

Nurbo, Johanna; Ericsson, Daniel J.; Rosenström, Ulrika; Muthas, Daniel et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 1992-2000, 2013

• DOI för Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic – targeting Mycobacterium tuberculosis ribonucleotide reductase

Synthesis and preclinical evaluation of Ga-68-labelled collagelin analogues for imaging and quantification of fibrosis

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof; Antoni, Gunnar

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013

Selective angiotensin II AT2 receptor agonists: Benzamide structure–activity relationships

Wallinder, Charlotta; Botros, Milad; Rosenström, Ulrika; Guimond, Marie-Odile et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 6841-6849, 2008

• DOI för Selective angiotensin II AT2 receptor agonists: Benzamide structure–activity relationships

Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT(1) and AT(2) receptors

Rosenström, Ulrika; Sköld, Christian; Lindeberg, Gunnar; Botros, Milad et al.

Ingår i Journal of Medicinal Chemistry, s. 6133-6137, 2006

• DOI för Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT(1) and AT(2) receptors

Short pseudopeptides containing turn scaffolds with high AT(2) receptor affinity

Georgsson, Jennie; Rosenström, Ulrika; Wallinder, Charlotta; Beaudry, Hélène et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5963-5972, 2006

• DOI för Short pseudopeptides containing turn scaffolds with high AT(2) receptor affinity

New selective AT2 receptor ligands encompassing a γ-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists

Rosenström, Ulrika; Sköld, Christian; Plouffe, Bianca; Beaudry, Hélène et al.

Ingår i Journal of Medicinal Chemistry, s. 4009-4024, 2005

• DOI för New selective AT2 receptor ligands encompassing a γ-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists

A Selective AT2 Receptor Ligand with a γ-Turn-Like Mimetic replacing the Amino Acid Residues 4-5 of Angiotensin II

Rosenström, Ulrika; Sköld, Christian; Lindeberg, Gunnar; Botros, Milad et al.

Ingår i Journal of Medicinal Chemistry, s. 859-870, 2004

• DOI för A Selective AT2 Receptor Ligand with a γ-Turn-Like Mimetic replacing the Amino Acid Residues 4-5 of Angiotensin II

Synthesis and AT2 receptor-binding properties of angiotensin II analogues

Rosenström, Ulrika; Sköld, Christian; Lindeberg, Gunnar; Botros, Milad et al.

Ingår i Journal of Peptide Research, s. 194-201, 2004

• DOI för Synthesis and AT2 receptor-binding properties of angiotensin II analogues

Design and Synthesis of AT₂ Receptor Selective Angiotensin II Analogues Encompassing β- and γ-Turn Mimetics

Rosenström, Ulrika

2004

• Ladda ner fulltext (pdf) av Design and Synthesis of AT₂ Receptor Selective Angiotensin II Analogues Encompassing β- and γ-Turn Mimetics

Synthesis and Preclinical Evaluation of GRPR Antagonist [¹⁸F]-MeTz-PEG₂-RM26 for Position Emission Tomography

Lundmark, Fanny; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir et al.