Lars Bohlin

35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Bohlin, Lars; Cárdenas, Paco; Backlund, Anders; Göransson, Ulf

Ingår i Progress in molecular and subcellular biology, s. 1-34, 2017

• DOI för 35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti

Carstens, Bodil B.; Rosengren, K. Johan; Gunasekera, Sunithi; Schempp, Stefanie et al.

Ingår i Journal of natural products (Print), s. 1886-1893, 2015

• DOI för Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti

Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

Svahn, Stefan; Chryssanthou, Erja; Olsen, Björn; Bohlin, Lars et al.

Ingår i Fungal biology and biothechnology, 2015

• DOI för Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B
• Ladda ner fulltext (pdf) av Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration

Wang, Likui; Gao, Shijuan; Jiang, Wei; Luo, Cheng et al.

Ingår i International Journal of Molecular Sciences, s. 16226-16245, 2014

• DOI för Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration

Bioassays in Natural Product Research: Strategies and Methods in the Search for Anti-inflammatory and Antimicrobial Activity

Strömstedt, Adam A.; Felth, Jenny; Bohlin, Lars

Ingår i Phytochemical Analysis, s. 13-28, 2014

• DOI för Bioassays in Natural Product Research: Strategies and Methods in the Search for Anti-inflammatory and Antimicrobial Activity

35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Bohlin, Lars; Cárdenas, Paco; Backlund, Anders; Göransson, Ulf

Ingår i Progress in molecular and subcellular biology, s. 1-34, 2017

• DOI för 35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti

Carstens, Bodil B.; Rosengren, K. Johan; Gunasekera, Sunithi; Schempp, Stefanie et al.

Ingår i Journal of natural products (Print), s. 1886-1893, 2015

• DOI för Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti

Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

Svahn, Stefan; Chryssanthou, Erja; Olsen, Björn; Bohlin, Lars et al.

Ingår i Fungal biology and biothechnology, 2015

• DOI för Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B
• Ladda ner fulltext (pdf) av Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

Bioassays in natural product research - Strategies and methods in the search for bioactive natural products

Bohlin, Lars; Felth, Jenny; Strömstedt, Adam A.

Ingår i Planta Medica, s. 753-753, 2014

Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

Felth, Jenny; Lesiak-Mieczkowska, Karolina; Haglund, Caroline; Gullbo, Joachim et al.

Ingår i Investigational new drugs, s. 587-598, 2013

• DOI för Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

Virtual and In vitro bioassay screening of phytochemical inhibitors from flavonoids and isoflavones against Xanthine oxidase and Cyclooxygenase-2 for gout treatment

Li, Yadi; Frenz, Christopher M; Li, Zhiwen; Chen, Mianhua et al.

Ingår i Chemical Biology and Drug Design, s. 537-544, 2013

• DOI för Virtual and In vitro bioassay screening of phytochemical inhibitors from flavonoids and isoflavones against Xanthine oxidase and Cyclooxygenase-2 for gout treatment

Bioassay-guided Supercritical Fluid Extraction of Cyclooxygenase-2 Inhibiting Substances in Plantago major L.

Stenholm, A.; Göransson, Ulf; Bohlin, Lars

Ingår i Phytochemical Analysis, s. 176-183, 2013

• DOI för Bioassay-guided Supercritical Fluid Extraction of Cyclooxygenase-2 Inhibiting Substances in Plantago major L.

Antimicrobial activity of filamentous fungi isolated from highly antibiotic-contaminated river sediment

Svahn, Stefan; Göransson, Ulf; El-Seedi, Hesham; Bohlin, Lars et al.

Ingår i Infection Ecology & Epidemiology, s. 11591, 2012

• DOI för Antimicrobial activity of filamentous fungi isolated from highly antibiotic-contaminated river sediment

The search for new antibiotic substances from filamentous fungi

Svahn, K. Stefan; Goransson, Ulf; Strömstedt, Adam A.; El-Seedi, Hesham et al.

Ingår i Planta Medica, s. 1162-1162, 2012

• DOI för The search for new antibiotic substances from filamentous fungi

Strategies and methods for a sustainable search for bioactive compounds

Bohlin, Lars; Alsmark, Cecilia; Göransson, Ulf; Klum, M. et al.

Ingår i Planta Medica, s. 1031-1032, 2012

• DOI för Strategies and methods for a sustainable search for bioactive compounds

Antimicrobial and antineoplastic activities of Agelasine analogs modified in the purine 2-position

Roggen, Heidi; Charnock, Colin; Burman, Robert; Felth, Jenny et al.

Ingår i Archiv der Pharmazie, s. 50-55, 2011

• DOI för Antimicrobial and antineoplastic activities of Agelasine analogs modified in the purine 2-position

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa

Ruhaak, Lucia Renee; Felth, Jenny; Karlsson, Pernilla Christina; Rafter, Joseph James et al.

Ingår i Biological and Pharmaceutical Bulletin, s. 774-778, 2011

2-Substituted agelasine analogs: Synthesis and biological activity, and structure and reactivity of synthetic intermediates

Roggen, Heidi; Bohlin, Lars; Burman, Robert; Charnock, Colin et al.

Ingår i Pure and Applied Chemistry, s. 645-653, 2011

• DOI för 2-Substituted agelasine analogs: Synthesis and biological activity, and structure and reactivity of synthetic intermediates

Two Brominated Cyclic Dipeptides Released by the Coldwater Marine Sponge Geodia barretti Act in Synergy As Chemical Defense

Sjögren, Martin; Jonsson, Per R.; Dahlström, Mia; Lundälv, Tomas et al.

Ingår i Journal of natural products (Print), s. 449-454, 2011

• DOI för Two Brominated Cyclic Dipeptides Released by the Coldwater Marine Sponge Geodia barretti Act in Synergy As Chemical Defense

Ex Vivo Activity of Cardiac Glycosides in Acute Leukaemia

Hallböök, Helene; Felth, Jenny; Eriksson, Anna; Fryknäs, Mårten et al.

Ingår i PLOS ONE, 2011

• DOI för Ex Vivo Activity of Cardiac Glycosides in Acute Leukaemia

Isolation, Characterization, and Bioactivity of Cyclotides from the Micronesian Plant Psychotria leptothyrsa

Gerlach, Samantha L.; Burman, Robert; Bohlin, Lars; Mondal, Debasis et al.

Ingår i Journal of natural products (Print), s. 1207-1213, 2010

• DOI för Isolation, Characterization, and Bioactivity of Cyclotides from the Micronesian Plant Psychotria leptothyrsa

Natural products in modern life science

Bohlin, Lars; Göransson, Ulf; Alsmark, Cecilia; Wedén, Christina et al.

Ingår i Phytochemistry Reviews, s. 279-301, 2010

• DOI för Natural products in modern life science

Evaluation of toxicity and anti-tumour activity of cycloviolacin O2 in mice.

Burman, Robert; Svedlund, Erika; Felth, Jenny; Hassan, Saadia et al.

Ingår i Biopolymers, s. 626-634, 2010

• DOI för Evaluation of toxicity and anti-tumour activity of cycloviolacin O2 in mice.

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

Wang, Conan K; Hu, Shu-Hong; Martin, Jennifer L; Sjögren, Tove et al.

Ingår i Journal of Biological Chemistry, s. 10672-10683, 2009

• DOI för Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

ChemGPS-NP mapping of chemical compounds for prediction of anticancer mode of action

Rosén, Josefin; Rickardson, Linda; Backlund, Anders; Gullbo, Joachim et al.

Ingår i QSAR & combinatorial science (Print), s. 436-446, 2009

• DOI för ChemGPS-NP mapping of chemical compounds for prediction of anticancer mode of action

Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs

Felth, Jenny; Rickardson, Linda; Rosén, Josefin; Wickström, Malin et al.

Ingår i Journal of natural products (Print), s. 1969-1974, 2009

• DOI för Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs

NMR metabolomic analysis of fecal water from subjects on a vegetarian diet

Pettersson, Jenny; Karlsson, Pernilla Christina; Choi, Young Hae; Verpoorte, Robert et al.

Ingår i Biological and Pharmaceutical Bulletin, s. 1192-1198, 2008

• DOI för NMR metabolomic analysis of fecal water from subjects on a vegetarian diet

The flavouring phytochemical 2-pentanone reduces prostaglandin production and COX-2 expression in colon cancer cells

Pettersson, Jenny; Karlsson, Pernilla Christina; Göransson, Ulf; Rafter, Joseph James et al.

Ingår i Biological and Pharmaceutical Bulletin, s. 534-537, 2008

• DOI för The flavouring phytochemical 2-pentanone reduces prostaglandin production and COX-2 expression in colon cancer cells

Screening for Anti-Inflammatory Activity of 12 Arnica (Asteraceae) Species Assessed by Inhibition of NF-κB and Release of Human Neutrophil Elastase

Ekenäs, Catarina; Zebrowska, Anna; Schuler, Barbara; Vrede, Tobias et al.

Ingår i Planta Medica, s. 1789-1794, 2008

• DOI för Screening for Anti-Inflammatory Activity of 12 Arnica (Asteraceae) Species Assessed by Inhibition of NF-κB and Release of Human Neutrophil Elastase

Antifouling activity of the sponge metabolite agelasine D and synthesised analogs on Balanus improvisus.

Sjögren, Martin; Dahlström, Mia; Hedner, Erik; Jonsson, Per R. et al.

Ingår i Biofouling (Print), s. 251-258, 2008

• DOI för Antifouling activity of the sponge metabolite agelasine D and synthesised analogs on Balanus improvisus.

Antifouling activity of a dibrominated cyclopeptide from the marine sponge Geodia barretti

Hedner, Erik; Sjögren, Martin; Hodzic, Said; Andersson, Rolf et al.

Ingår i Journal of natural products (Print), s. 330-333, 2008

• DOI för Antifouling activity of a dibrominated cyclopeptide from the marine sponge Geodia barretti

Reappraising a decade old explanatory model for pharmacognosy

Larsson, Sonny; Backlund, Anders; Bohlin, Lars

Ingår i Phytochemistry Letters, s. 131-134, 2008

• DOI för Reappraising a decade old explanatory model for pharmacognosy

Antifouling activity of bromotyrosine-derived sponge metabolites and synthetic analogues

Ortlepp, Sofia; Sjögren, Martin; Dahlström, Mia; Weber, Horst et al.

Ingår i Marine Biotechnology, s. 776-785, 2007

• DOI för Antifouling activity of bromotyrosine-derived sponge metabolites and synthetic analogues

Modern pharmacognosy: Connecting biology and chemistry

Bohlin, Lars; Göransson, Ulf; Backlund, Anders

Ingår i Pure and Applied Chemistry, s. 763-774, 2007

• DOI för Modern pharmacognosy: Connecting biology and chemistry

Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a beta-cyclocitral derived substituent.

Proszenyák, Agnes; Charnock, Colin; Hedner, Erik; Larsson, Rolf et al.

Ingår i Archiv der Pharmazie, s. 625-634, 2007

• DOI för Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a beta-cyclocitral derived substituent.

Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs

Vik, Anders; Hedner, Erik; Charnock, Colin; Tangen, Linda et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 4016-4037, 2007

• DOI för Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs

Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin

Sjögren, Martin; Johnson, Ann-Louise; Hedner, Erik; Dahlström, Mia et al.

Ingår i Peptides, s. 2058-2064, 2006

• DOI för Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin

(+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities.

Vik, Anders; Hedner, Erik; Charnock, Colin; Samuelsen, Orjan et al.

Ingår i J Nat Prod, s. 381-6, 2006

Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial

Luo, Cheng; He, Ming-liang; Bohlin, Lars

Ingår i Acta Pharmacologica Sinica, s. 926-933, 2005

• DOI för Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial

Synthesis of barettin

Johnson, Ann-Louise; Bergman, Jan; Sjögren, Martin; Bohlin, Lars

Ingår i Tetrahedron, s. 961-965, 2004

• DOI för Synthesis of barettin

Variations in cyclotide expression in viola species

Trabi, Manuela; Svangård, Erika; Herrmann, Anders; Göransson, Ulf et al.

Ingår i Journal of natural products (Print), s. 806-10, 2004

• DOI för Variations in cyclotide expression in viola species

Isolation of high purity 1-[2′,4′-dihydroxy-3′,5′-di-(3″-methylbut-2″-enyl)-6′-methoxy] phenylethanone from Acronychia pedunculata (L.) Miq. by high-speed counter-current chromatography

Han, Xiao; Pathmasiri, Wimal; Bohlin, Lars; Janson, Jan-Christer

Ingår i Journal of Chromatography A, s. 213-216, 2004

• DOI för Isolation of high purity 1-[2′,4′-dihydroxy-3′,5′-di-(3″-methylbut-2″-enyl)-6′-methoxy] phenylethanone from Acronychia pedunculata (L.) Miq. by high-speed counter-current chromatography

Novel strategies for isolation and characterization of cyclotides: the discovery of bioactive macrocyclic plant polypeptides in the Violaceae

Göransson, Ulf; Svangård, Erika; Claeson, Per; Bohlin, Lars

Ingår i Current protein and peptide science, s. 317-29, 2004

Cytotoxic cyclotides from Viola tricolor

Svangård, Erika; Göransson, Ulf; Hocaoglu, Zozan; Gullbo, Joachim et al.

Ingår i Journal of natural products (Print), s. 144-7, 2004

• DOI för Cytotoxic cyclotides from Viola tricolor

Reversible Antifouling Effect of the Cyclotide Cycloviolacin O2 against Barnacles.

Göransson, Ulf; Sjögren, Martin; Svangård, Erika; Claeson, Per et al.

Ingår i J Nat Prod, s. 1287-90, 2004

Recruitment in the field of Balanus improvisus and Mytilus edulis in response to the antifouling cyclopeptides barettin and 8,9-dihydrobarettin from the marine sponge Geodia barretti.

Sjögren, Martin; Dahlström, Mia; Göransson, Ulf; Jonsson, Per R et al.

Ingår i Biofouling, s. 291-7, 2004

A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products

Johansson, Senia; Göransson, Ulf; Luijendijk, Teus; Backlund, Anders et al.

Ingår i Journal of natural products (Print), s. 32-41, 2002

• DOI för A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products

Cyclotides: a novel type of cytotoxic agents

Lindholm, Petra; Göransson, Ulf; Johansson, Senia; Claeson, Per et al.

Ingår i Molecular Cancer Therapeutics, s. 365-369, 2002

Amentoflavone from Biophytum sensitivum and its effect on COX-1/COX-2 catalysed prostaglandin biosynthesis

Bucar, Franz; Jachak, Sanjay M.; Noreen, Ylva; Kartnig, Theodor et al.

Ingår i Planta Medica, s. 373-374, 1998

• DOI för Amentoflavone from Biophytum sensitivum and its effect on COX-1/COX-2 catalysed prostaglandin biosynthesis

Fractionation protocol for the isolation of polypeptides from plant biomass

Claeson, Per; Göransson, Ulf; Johansson, Senia; Luijendijk, Teus et al.

Ingår i Journal of natural products (Print), s. 77-81, 1998

• DOI för Fractionation protocol for the isolation of polypeptides from plant biomass

Some aspects of bioassay methods in natural-product research aimed at drugl ead discovery

Claeson, Per; Bohlin, Lars

Ingår i Trends in Biotechnology, s. 245-248, 1997

• DOI för Some aspects of bioassay methods in natural-product research aimed at drugl ead discovery

Bioassays using the phospholipid mediator PAF in the search for anti-inflammatory natural products

Bohlin, Lars; Vasänge, M.; Perera, P.

Ingår i Current organic chemistry, s. 345-360, 1997

Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration

Wang, Likui; Gao, Shijuan; Jiang, Wei; Luo, Cheng et al.

Ingår i International Journal of Molecular Sciences, s. 16226-16245, 2014

• DOI för Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration

Bioassays in Natural Product Research: Strategies and Methods in the Search for Anti-inflammatory and Antimicrobial Activity

Strömstedt, Adam A.; Felth, Jenny; Bohlin, Lars

Ingår i Phytochemical Analysis, s. 13-28, 2014

• DOI för Bioassays in Natural Product Research: Strategies and Methods in the Search for Anti-inflammatory and Antimicrobial Activity

In silico comparison of marine, terrestrial and synthetic compounds using ChemGPS-NP for navigating chemical space

Muigg, Patrik; Rosen, Josefin; Bohlin, Lars; Backlund, Anders

Ingår i Phytochemistry Reviews, s. 449-457, 2013

• DOI för In silico comparison of marine, terrestrial and synthetic compounds using ChemGPS-NP for navigating chemical space

Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids

El-Seedi, Hesham; El-Said, A. M. A.; Khalifa, S. A. M.; Göransson, Ulf et al.

Ingår i Journal of Agricultural and Food Chemistry, s. 10877-10895, 2012

• DOI för Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids

Recent insights into the biosynthesis and biological activities of natural xanthones

El-Seedi, Hesham R.; El-Barbary, M. A.; El-Ghorab, D. M. H.; Bohlin, Lars et al.

Ingår i Current Medicinal Chemistry, s. 854-901, 2010

• DOI för Recent insights into the biosynthesis and biological activities of natural xanthones

Molecular Pharmacognosy: an explanatory model

Bruhn, Jan G.; Bohlin, Lars

Ingår i Drug Discovery Today, s. 243-246, 1997

• DOI för Molecular Pharmacognosy: an explanatory model

Podophyllotoxin derivatives: drug discovery and development

Bohlin, Lars; Rosén, Börje

Ingår i Drug Discovery Today, s. 343-351, 1996

• DOI för Podophyllotoxin derivatives: drug discovery and development

Växter i moderna läkemedel

Bohlin, Lars

Ingår i Ett växande vetande, s. 103, Vetenskapsrådet, 2002

Microwave-assisted solid phase peptide synthesis of Asteropine A

Koptina, Anna; Gunasekera, Sunithi; Muhammad, Taj; Bohlin, Lars et al.

Ingår i Phytopharm 2014, Saint-Petersburg, Russia 3-5 July 2014, s. 36, 2014

• Ladda ner fulltext (pdf) av Microwave-assisted solid phase peptide synthesis of Asteropine A

Bis(methyl)gliotoxin and gliotoxin in bronchoalveolar lavage fluids are not suitable markers for invasive aspergillosis

Svahn, Stefan; Göransson, Ulf; Chryssanthou, Erja; Bohlin, Lars et al.

Bioassay methods in natural product research and drug development: proceedings of the international symposium on Bioassay Methods in Natural Product Research and Drug Development, held at the Biomedical Centre of Uppsala University, Sweden, from 24-27 August 1997

Bohlin, Lars; Bruhn, Jan G.

1999