Jarl Wikberg
Professor emer. vid Institutionen för farmaceutisk biovetenskap; Forskning; Farmaceutisk bioinformatik
- E-post:
- jarl.wikberg@uu.se
- Besöksadress:
- Biomedicinskt centrum BMC, Husargatan 3
- Postadress:
- Box 591
751 24 UPPSALA
- Akademiska meriter:
- MD
Publikationer
Senaste publikationer
Towards Predicting the Cytochrome P450 Modulation: From QSAR to proteochemometric modeling.
Ingår i Current drug metabolism, s. 540-555, 2017
PepBio: predicting the bioactivity of host defense peptides
Ingår i RSC Advances, s. 35119-35134, 2017
Exploring the epigenetic drug discovery landscape
Ingår i Expert Opinion on Drug Discovery, s. 345-362, 2017
Ingår i Scandinavian Journal of Immunology, s. 31-39, 2017
HemoPred: a web server for predicting the hemolytic activity of peptides
Ingår i Future Medicinal Chemistry, s. 275-291, 2017
Alla publikationer
Artiklar i tidskrift
Towards Predicting the Cytochrome P450 Modulation: From QSAR to proteochemometric modeling.
Ingår i Current drug metabolism, s. 540-555, 2017
PepBio: predicting the bioactivity of host defense peptides
Ingår i RSC Advances, s. 35119-35134, 2017
Ingår i Scandinavian Journal of Immunology, s. 31-39, 2017
HemoPred: a web server for predicting the hemolytic activity of peptides
Ingår i Future Medicinal Chemistry, s. 275-291, 2017
CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins
Ingår i Journal of Chemistry, 2017
- DOI för CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins
- Ladda ner fulltext (pdf) av CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins
Resistin Gene Transcription Is Regulated in Adaptive and Innate Immunity in Rheumatoid Arthritis
Ingår i Annals of the Rheumatic Diseases, s. 904-904, 2016
Ingår i Annals of the Rheumatic Diseases, s. 903-904, 2016
Origin of aromatase inhibitory activity via proteochemometric modeling
Ingår i PeerJ, 2016
- DOI för Origin of aromatase inhibitory activity via proteochemometric modeling
- Ladda ner fulltext (pdf) av Origin of aromatase inhibitory activity via proteochemometric modeling
Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking
Ingår i PeerJ, 2016
- DOI för Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking
- Ladda ner fulltext (pdf) av Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking
Large-scale ligand-based predictive modelling using support vector machines
Ingår i Journal of Cheminformatics, 2016
- DOI för Large-scale ligand-based predictive modelling using support vector machines
- Ladda ner fulltext (pdf) av Large-scale ligand-based predictive modelling using support vector machines
osFP: a web server for predicting the oligomeric states of fluorescent proteins
Ingår i Journal of Cheminformatics, 2016
- DOI för osFP: a web server for predicting the oligomeric states of fluorescent proteins
- Ladda ner fulltext (pdf) av osFP: a web server for predicting the oligomeric states of fluorescent proteins
Ingår i Scandinavian Journal of Immunology, s. 229-236, 2016
New Polyfunctional Phragmalin Limonoids from Neobeguea mahafalensis
Ingår i Planta Medica, s. 1087-1095, 2016
Ingår i Chemometrics and Intelligent Laboratory Systems, s. 219-227, 2016
Proteochemometric model for predicting the inhibition of penicillin-binding proteins
Ingår i Journal of Computer-Aided Molecular Design, s. 127-141, 2015
Ingår i Scandinavian Journal of Rheumatology, s. 25-26, 2014
Ingår i Journal of Computational Chemistry, s. 1951-1966, 2014
Ligand-Based Target Prediction with Signature Fingerprints
Ingår i Journal of Chemical Information and Modeling, s. 2647-2653, 2014
Ingår i Planta Medica, s. 306-314, 2014
Ingår i Journal of Chemical Information and Modeling, s. 3211-3217, 2014
Semisynthesis of Libiguin A and Its Analogues by Trans-Lactonization of Phragmalin
Ingår i Journal of Organic Chemistry, s. 4148-4153, 2014
Bioclipse-R: Integrating management and visualization of life science data with statistical analysis
Ingår i Bioinformatics, s. 286-289, 2013
A Unified Proteochemometric Model for Prediction of Inhibition of Cytochrome P450 Isoforms
Ingår i PLOS ONE, 2013
- DOI för A Unified Proteochemometric Model for Prediction of Inhibition of Cytochrome P450 Isoforms
- Ladda ner fulltext (pdf) av A Unified Proteochemometric Model for Prediction of Inhibition of Cytochrome P450 Isoforms
Net present value approaches for drug discovery
Ingår i SpringerPlus, 2013
- DOI för Net present value approaches for drug discovery
- Ladda ner fulltext (pdf) av Net present value approaches for drug discovery
Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 767-772, 2013
- DOI för Design and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases
- Ladda ner fulltext (pdf) av Design and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases
Melanocortin 4 receptor in silico mutagenesis and docking studies
Ingår i European Biophysics Journal, 2013
Ingår i Biochemistry (Moscow), s. 925-932, 2013
Ingår i Biochemistry (Moscow), s. 920-924, 2013
Ingår i PLOS ONE, 2012
- DOI för Enzymatic Analysis of Recombinant Japanese Encephalitis Virus NS2B(H)-NS3pro Protease with Fluorogenic Model Peptide Substrates
- Ladda ner fulltext (pdf) av Enzymatic Analysis of Recombinant Japanese Encephalitis Virus NS2B(H)-NS3pro Protease with Fluorogenic Model Peptide Substrates
Dermal Melanocortin Receptor Rebound in Diffuse Systemic Sclerosis after Anti-TGFβ1 Antibody Therapy
Ingår i Scandinavian Journal of Immunology, s. 478-482, 2012
A new protolimonoid from Capuronianthus mahafalensis
Ingår i Fitoterapia (Milano), s. 901-906, 2012
Linking the Resource Description Framework to cheminformatics and proteochemometrics
Ingår i Journal of Biomedical Semantics, s. 6, 2011
Ingår i BMC Bioinformatics, 2011
- DOI för Brunn: an open source laboratory information system for microplates with a graphical plate layout design process
- Ladda ner fulltext (pdf) av Brunn: an open source laboratory information system for microplates with a graphical plate layout design process
Ingår i Bioinformatics, s. 1719-1720, 2011
Ingår i PLoS ONE, 2010
Towards interoperable and reproducible QSAR analyses: Exchange of data sets
Ingår i Journal of Cheminformatics, 2010
- DOI för Towards interoperable and reproducible QSAR analyses: Exchange of data sets
- Ladda ner fulltext (pdf) av Towards interoperable and reproducible QSAR analyses: Exchange of data sets
An eScience-Bayes strategy for analyzing omics data
Ingår i BMC Bioinformatics, s. 282, 2010
Ingår i BMC Bioinformatics, s. 339, 2010
Towards proteome-wide interaction models using the proteochemometrics approach
Ingår i Molecular Informatics, s. 499-508, 2010
Ingår i BMC Bioinformatics, s. 279, 2009
- DOI för XMPP for cloud computing in bioinformatics supporting discovery and invocation of asynchronous web services
- Ladda ner fulltext (pdf) av XMPP for cloud computing in bioinformatics supporting discovery and invocation of asynchronous web services
Bioclipse 2: A scriptable integration platform for the life sciences
Ingår i BMC Bioinformatics, s. 397, 2009
- DOI för Bioclipse 2: A scriptable integration platform for the life sciences
- Ladda ner fulltext (pdf) av Bioclipse 2: A scriptable integration platform for the life sciences
Ingår i Journal of chemical information and modeling, s. 1202-1210, 2009
The C1C2: a framework for simultaneous model selection and assessment
Ingår i BMC Bioinformatics, s. 360, 2008
Proteochemometric modeling of HIV protease susceptibility
Ingår i BMC Bioinformatics, s. 181, 2008
Oligomerization of indole derivatives with incorporation of thiols
Ingår i Molecules, s. 1846-63, 2008
Improving the affinity of antigens for mutated antibodies by use of statistical molecular design
Ingår i Journal of Peptide Science, s. 786-96, 2008
Generalized proteochemometric model of multiple cytochrome P450 enzymes and their inhibitors
Ingår i Journal of chemical information and modeling, s. 1840-1850, 2008
Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases
Ingår i Bioorganic & Medicinal Chemistry, s. 9369-9377, 2008
Bioclipse: an open source workbench for chemo- and bioinformatics
Ingår i BMC Bioinformatics, s. 59, 2007
- DOI för Bioclipse: an open source workbench for chemo- and bioinformatics
- Ladda ner fulltext (pdf) av Bioclipse: an open source workbench for chemo- and bioinformatics
Ingår i Proteins, s. 83-96, 2007
Computational proteomics analysis of HIV-1 protease interactome
Ingår i Proteins, s. 305-312, 2007
A look inside HIV resistance through retroviral protease interaction maps
Ingår i PloS Computational Biology, s. 424-435, 2007
Ingår i Proteins, s. 653-660, 2007
QSAR of multiple mutated antibodies
Ingår i Journal of Molecular Recognition, s. 97-102, 2007
Ingår i Bioorganic & Medicinal Chemistry, s. 5787-5810, 2007
Proteochemometric modelling of antibody-antigen interactions using SPOT synthesised peptide arrays
Ingår i Protein Engineering Design & Selection, s. 301-307, 2007
Rough set-based proteochemometrics modeling of G-protein-coupled receptor-ligand
Ingår i Proteins, s. 24-34, 2006
Trigger factor binding to ribosomes with nascent peptide chains of varying lengths and sequences
Ingår i Journal of Biological Chemistry, s. 28033-28038, 2006
Ingår i Brain Research, s. 139-147, 2003
Ingår i European Journal of Neuroscience, s. 291-296, 2001
Ingår i Neurochem Int, s. 95-9, 1997
Ingår i Pharmacol Toxicol, s. 353-64, 1995
Artiklar, forskningsöversikt
Exploring the epigenetic drug discovery landscape
Ingår i Expert Opinion on Drug Discovery, s. 345-362, 2017
Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides
Ingår i International Journal of Molecular Sciences, 2016
- DOI för Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides
- Ladda ner fulltext (pdf) av Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Ingår i Nature reviews. Drug discovery, s. 307-323, 2008
Böcker
Introduction to Pharmaceutical Bioinformatics
Oakleaf Academic, 2010
Kapitel i böcker, delar av antologi
Chemoinformatics taking Biology into Account: Proteochemometrics
Ingår i Computational Approaches in Cheminformatics and Bioinformatics, John Wiley & Sons, 2012
Konferensbidrag
Linking Open Drug Data to Cheminformatics and Proteochemometrics
Ingår i SWAT4LS-2009 - Semantic Web Applications and Tools for Life Sciences, 2010