Leif Kirsebom

Age-dependent pleomorphism in Mycobacterium monacense cultures

Ramesh, Malavika; Behra, Phani Rama Krishna; Pettersson, B. M. Fredrik; Das, Sarbashis et al.

Ingår i Microorganisms, 2025

• DOI för Age-dependent pleomorphism in Mycobacterium monacense cultures
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RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5' leader

Kosek, David; Leal, J. Luis; Kikovska-Stojanovska, Ema; Mao, Guanzhong et al.

Ingår i RNA Biology, s. 1-19, 2025

• DOI för RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5' leader
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Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Babina, Arianne M.; Kirsebom, Leif; Andersson, Dan I.

Ingår i RNA, s. 977-991, 2024

• DOI för Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations
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The discovery of a catalytic RNA within RNase P and its legacy

Kirsebom, Leif; Liu, Fenyong; Mcclain, William H.

Ingår i Journal of Biological Chemistry, 2024

• DOI för The discovery of a catalytic RNA within RNase P and its legacy
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A tribute to Sidney Altman, one of the architects of modern RNA biology

Gopalan, Venkat; Kirsebom, Leif

Ingår i Journal of Biological Chemistry, 2024

• DOI för A tribute to Sidney Altman, one of the architects of modern RNA biology
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Age-dependent pleomorphism in Mycobacterium monacense cultures

Ramesh, Malavika; Behra, Phani Rama Krishna; Pettersson, B. M. Fredrik; Das, Sarbashis et al.

Ingår i Microorganisms, 2025

• DOI för Age-dependent pleomorphism in Mycobacterium monacense cultures
• Ladda ner fulltext (pdf) av Age-dependent pleomorphism in Mycobacterium monacense cultures

RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5' leader

Kosek, David; Leal, J. Luis; Kikovska-Stojanovska, Ema; Mao, Guanzhong et al.

Ingår i RNA Biology, s. 1-19, 2025

• DOI för RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5' leader
• Ladda ner fulltext (pdf) av RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5' leader

Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Babina, Arianne M.; Kirsebom, Leif; Andersson, Dan I.

Ingår i RNA, s. 977-991, 2024

• DOI för Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations
• Ladda ner fulltext (pdf) av Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

A tribute to Sidney Altman, one of the architects of modern RNA biology

Gopalan, Venkat; Kirsebom, Leif

Ingår i Journal of Biological Chemistry, 2024

• DOI för A tribute to Sidney Altman, one of the architects of modern RNA biology
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Importance of residue 248 in Escherichia coli RNase P RNA mediated cleavage

Mao, Guanzhong; Srivastava, Abhishek S.; Wu, Shiying; Kosek, David et al.

Ingår i Scientific Reports, 2023

• DOI för Importance of residue 248 in Escherichia coli RNase P RNA mediated cleavage
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Sidney Altman: A brief memoir

Kirsebom, Leif A.

Ingår i RNA, s. 1404-1405, 2022

Comparative genome analysis of Mycobacteria focusing on tRNA and non-coding RNA

Behra, Phani Rama Krishna; Pettersson, B. M. Fredrik; Ramesh, Malavika; Das, Sarbashis et al.

Ingår i BMC Genomics, 2022

• DOI för Comparative genome analysis of Mycobacteria focusing on tRNA and non-coding RNA
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Intracellular localization of the mycobacterial stressosome complex

Ramesh, Malavika; Nitharwal, Ram Gopal; Behra, Phani Rama Krishna; Pettersson, B. M. Fredrik et al.

Ingår i Scientific Reports, 2021

• DOI för Intracellular localization of the mycobacterial stressosome complex
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Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA

Behra, Phani Rama Krishna; Pettersson, Fredrik; Das, Sarbashis; Dasgupta, Santanu et al.

Ingår i BMC Evolutionary Biology, 2019

• DOI för Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA
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Gene miaA for post-transcriptional modification of tRNA_XXA is important for morphological and metabolic differentiation in Streptomyces

Koshla, Oksana; Yushchuk, Oleksandr; Stash, Iryna; Dacyuk, Yuriy et al.

Ingår i Molecular Microbiology, s. 249-265, 2019

• DOI för Gene miaA for post-transcriptional modification of tRNA_XXA is important for morphological and metabolic differentiation in Streptomyces

Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains

Behra, Phani Rama Krishna; Das, Sarbashis; Pettersson, B. M. Fredrik; Shirreff, Lisa et al.

Ingår i Scientific Reports, 2019

• DOI för Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains
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Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum Glade members

Behra, Phani Rama Krishna; Pettersson, Fredrik; Ramesh, Malavika; Dasgupta, Santanu et al.

Ingår i Scientific Reports, 2019

• DOI för Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum Glade members
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Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain

Mao, Guanzhong; Srivastava, Abhishek S.; Wu, Shiying; Kosek, David et al.

Ingår i PLOS ONE, 2018

• DOI för Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain
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Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing

Das, Sarbashis; Pettersson, B. M. Fredrik; Behra, Phani Rama Krishna; Mallick, Amrita et al.

Ingår i Scientific Reports, 2018

• DOI för Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing
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Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

Wu, Shiying; Mao, Guanzhong; Kirsebom, Leif A.

Ingår i Biomolecules, 2016

• DOI för Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives
• Ladda ner fulltext (pdf) av Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

The Mycobacterium phlei Genome: Expectations and Surprises

Das, Sarbashis; Pettersson, B. M. Fredrik; Behra, Phani Rama Krishna; Ramesh, Malavika et al.

Ingår i Genome Biology and Evolution, s. 975-985, 2016

• DOI för The Mycobacterium phlei Genome: Expectations and Surprises
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Cleavage of Model Substrates by Arabidopsis thaliana PRORP1 Reveals New Insights into Its Substrate Requirements

Mao, Guanzhong; Chen, Tien-Hao; Srivastava, Abhishek S.; Kosek, David et al.

Ingår i PLOS ONE, 2016

• DOI för Cleavage of Model Substrates by Arabidopsis thaliana PRORP1 Reveals New Insights into Its Substrate Requirements
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Characterization of three Mycobacterium spp. with potential use in bioremediation by genome sequencing and comparative genomics

Das, Sarbashis; Pettersson, B M Fredrik; Behra, Phani Rama Krishna; Ramesh, Malavika et al.

Ingår i Genome Biology and Evolution, s. 1871-1886, 2015

• DOI för Characterization of three Mycobacterium spp. with potential use in bioremediation by genome sequencing and comparative genomics
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Comparative Sigma Factor-mRNA Levels in Mycobacterium marinum under Stress Conditions and during Host Infection

Pettersson, B. M. Fredrik; Das, Sarbashis; Behra, Phani Rama Krishna; Jordan, Heather R. et al.

Ingår i PLOS ONE, 2015

• DOI för Comparative Sigma Factor-mRNA Levels in Mycobacterium marinum under Stress Conditions and during Host Infection

Transition-state stabilization in Escherichia coli ribonuclease P RNA-mediated cleavage of model substrates

Wu, Shiying; Chen, Yu; Mao, Guanzhong; Trobro, Stefan et al.

Ingår i Nucleic Acids Research, s. 631-642, 2014

• DOI för Transition-state stabilization in Escherichia coli ribonuclease P RNA-mediated cleavage of model substrates

Differentiation and Phylogenetic Relationships in Mycobacterium spp with Special Reference to the RNase P RNA Gene rnpB

Herrmann, Björn; Stolt, Pelle; Abdeldaim, Guma; Rubin, Carl-Johan et al.

Ingår i Current Microbiology, s. 634-639, 2014

• DOI för Differentiation and Phylogenetic Relationships in Mycobacterium spp with Special Reference to the RNase P RNA Gene rnpB

Asymmetric growth and division in Mycobacterium spp.: compensatory mechanisms for non-medial septa

Singh, Bhupender; Nitharwal, Ram Gopal; Ramesh, Malavika; Pettersson, B. M. Fredrik et al.

Ingår i Molecular Microbiology, s. 64-76, 2013

• DOI för Asymmetric growth and division in Mycobacterium spp.: compensatory mechanisms for non-medial septa

Identification and expression of stressosomal proteins in Mycobacterium marinum under various growth and stress conditions

Pettersson, B. M. Fredrik; Nitharwal, Ram Gopal; Das, Sarbashis; Behra, Krishna P. R. et al.

Ingår i FEMS Microbiology Letters, s. 98-105, 2013

• DOI för Identification and expression of stressosomal proteins in Mycobacterium marinum under various growth and stress conditions

Cleavage mediated by the P15 domain of bacterial RNase P RNA

Kikovska, Ema; Wu, Shiying; Mao, Guanzhong; Kirsebom, Leif A.

Ingår i Nucleic Acids Research, s. 2224-2233, 2012

• DOI för Cleavage mediated by the P15 domain of bacterial RNase P RNA

Cleavage mediated by the catalytic domain of bacterial RNase P RNA

Wu, Shiying; Kikovska, Ema; Lindell, Magnus; Kirsebom, Leif A.

Ingår i Journal of Molecular Biology, s. 204-214, 2012

• DOI för Cleavage mediated by the catalytic domain of bacterial RNase P RNA

Functional Coupling between a Distal Interaction and the Cleavage Site in Bacterial RNase-P-RNA-Mediated Cleavage

Wu, Shiying; Chen, Yu; Lindell, Magnus; Mao, Guanzhong et al.

Ingår i Journal of Molecular Biology, s. 384-396, 2011

• DOI för Functional Coupling between a Distal Interaction and the Cleavage Site in Bacterial RNase-P-RNA-Mediated Cleavage

tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor

Pettersson, B M Fredrik; Kirsebom, Leif A

Ingår i Molecular Microbiology, s. 1602-1614, 2011

• DOI för tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor

Sporulation in mycobacteria

Ghosh, Jaydip; Larsson, Pontus; Singh, Bhupender; Pettersson, B. M. Fredrik et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 10781-10786, 2009

• DOI för Sporulation in mycobacteria

The Presence of a C_− 1/G_+ 73 Pair in a tRNA Precursor Influences Processing and Expression In Vivo

Pettersson, B. M. Fredrik; Kirsebom, Leif A.

Ingår i Journal of Molecular Biology, s. 1089-1097, 2008

• DOI för The Presence of a C_− 1/G_+ 73 Pair in a tRNA Precursor Influences Processing and Expression In Vivo

De novo search for non-coding RNA genes in the AT-rich genome of Dictyostelium discoideum: Performance of Markov-dependent genome feature scoring

Larsson, Pontus; Hinas, Andrea; Ardell, David H.; Kirsebom, Leif A. et al.

Ingår i Genome Research, s. 888-899, 2008

• DOI för De novo search for non-coding RNA genes in the AT-rich genome of Dictyostelium discoideum: Performance of Markov-dependent genome feature scoring

Evidence for induced fit in bacterial RNase P RNA-mediated cleavage

Brännvall, Mathias; Kikovska, Ema; Wu, Shiying; Kirsebom, Leif A.

Ingår i Journal of Molecular Biology, s. 1149-1164, 2007

• DOI för Evidence for induced fit in bacterial RNase P RNA-mediated cleavage

Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Kikovska, Ema; Svärd, Staffan; Kirsebom, Leif

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 2062-2067, 2007

• DOI för Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Inhibition of poly(A) polymerase by aminoglycosides

Thuresson, Ann-Charlotte; Kirsebom, Leif A.; Virtanen, Anders

Ingår i Biochimie, s. 1221-1227, 2007

• DOI för Inhibition of poly(A) polymerase by aminoglycosides

Substrate discrimination in RNase P RNA-mediated cleavage: importance of the structural environment of the RNase P cleavage site.

Kikovska, Ema; Brännvall, Mathias; Kufel, Joanna; Kirsebom, Leif

Ingår i Nucleic Acids Res, s. 2012-21, 2005

Cross talk between the +73/294 interaction and the cleavage site in RNase P RNA mediated cleavage.

Brännvall, Mathias; Kikovska, Ema; Kirsebom, Leif

Ingår i Nucleic Acids Res, s. 5418-29, 2004

Importance of the +73/294 interaction in Escherichia coli RNase P RNA substrate complexes for cleavage and metal ion coordination.

Brännvall, Mathias; Pettersson, B M Fredrik; Kirsebom, Leif

Ingår i J Mol Biol, s. 697-709, 2003

The residue immediately upstream of the RNase P cleavage site is a positive determinant.

Brännvall, Mathias; Fredrik Pettersson, B M; Kirsebom, Leif

Ingår i Biochimie, s. 693-703, 2002

Inhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosides

Ren, Yan-Guo; Martínez, Javier; Kirsebom, Leif; Virtanen, Anders

Ingår i RNA, s. 1393-1400, 2002

• DOI för Inhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosides

Metal ion cooperativity in ribozyme cleavage of RNA

Brännvall, Mathias; Kirsebom, Leif

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 12943-12947, 2001

• DOI för Metal ion cooperativity in ribozyme cleavage of RNA

Escherichia coli ribonuclease P.

Kirsebom, Leif

Ingår i Methods Enzymol, s. 77-92, 2001

Differential role of the intermolecular base-pairs G292-C(75) and G293-C(74) in the reaction catalyzed by Escherichia coli RNase P RNA.

Busch, S; Kirsebom, Leif; Notbohm, H; Hartmann, R K

Ingår i J Mol Biol, s. 941-51, 2000

The discovery of a catalytic RNA within RNase P and its legacy

Kirsebom, Leif; Liu, Fenyong; Mcclain, William H.

Ingår i Journal of Biological Chemistry, 2024

• DOI för The discovery of a catalytic RNA within RNase P and its legacy
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Unexpected diversity of RNase P, an ancient tRNA processing enzyme: Challenges and prospects

Lai, Lien B.; Vioque, Agustin; Kirsebom, Leif A.; Gopalan, Venkat

Ingår i FEBS Letters, s. 287-296, 2010

• DOI för Unexpected diversity of RNase P, an ancient tRNA processing enzyme: Challenges and prospects

RNase P RNA-mediated cleavage

Kirsebom, Leif A.; Trobro, Stefan

Ingår i IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, s. 189-200, 2009

• DOI för RNase P RNA-mediated cleavage

Pb2+-Induced Cleavage of RNA

Kirsebom, Leif A.; Ciesiolka, Jerzy

Ingår i Handbook of RNA Biochemistry, s. 269-284, Wiley-Blackwell, 2014

• DOI för Pb2+-Induced Cleavage of RNA

Enzymatic RNA Synthesis Using Bacteriophage T7 RNA Polymerase

Gößringer, M.; Helmecke, D.; Köhler, K.; Schön, A. et al.

Ingår i Handbook of RNA Biochemistry, s. 1-28, Wiley-Blackwell, 2014

• DOI för Enzymatic RNA Synthesis Using Bacteriophage T7 RNA Polymerase

Pleiomorphism in Mycobacterium

Kirsebom, Leif A.; Dasgupta, Santanu; Pettersson, Fredrik M. Brännvall

Ingår i Advances in Applied Microbiology, Vol 80, s. 81-112, ELSEVIER ACADEMIC PRESS INC, 2012

• DOI för Pleiomorphism in Mycobacterium

Roles of metal ions in RNase P catalysis

Kirsebom, Leif A

Ingår i Ribonuclease P, s. 113-134, Springer-Verlag New York, 2010

• DOI för Roles of metal ions in RNase P catalysis

Inhibition of RNase P processing

Kirsebom, Leif; Virtanen, Anders

Ingår i RNA-Binding Antibiotics, s. 56-72, Eurekah.com, Austin, TX, USA and Landes Bioscences, Georgetown, TX, USA, 2001

Pleomorphism and gene expression profile of SGM Mycobacterium marinum and RGM Mycobacterium monacense under microaerobic condition

Ramesh, Malavika; Behra, Phani Rama Krishna; Raffetseder, Johanna; Lerm, Maria et al.

Branching morphology in the non-tuberculous mycobacteria Mycobacterium senegalense and Mycobacterium malmoense

Ramesh, Malavika; Behra, Phani Rama Krishna; Dasgupta, Santanu; Kirsebom, Leif

Age-dependent pleomorphism in Mycobacterium monacense cultures

Ramesh, Malavika; Behra, Phani Rama Krishna; Pettersson, B. M. Fredrik; Das, Sarbashis et al.

Insight into the presence of selenocysteine among mycobacteria

Behra, Phani Rama Krishna; Kirsebom, Leif

New Vaccines

Kirsebom, Leif A; DasGupta, Santanu; Larsson, Pontus; Ghosh, Jaydip

2009

Functional diversity of RNA

Gillet, Reynald; Kirsebom, Leif A

2007