Göran Alderborn

Packing, Flow and Aerosolization Properties of Binary Adhesive Mixtures Containing Micronized and Spray-Dried Drugs

Simonsson, Anna; Bunta Sundin, Nicklas; Bramer, Tobias; Wimbush, Alex et al.

Ingår i Pharmaceutics, 2026

• DOI för Packing, Flow and Aerosolization Properties of Binary Adhesive Mixtures Containing Micronized and Spray-Dried Drugs
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Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial

Holmbäck, Ulf; Grudén, Stefan; Kuusk, Sandra; Litorp, Helena et al.

Ingår i Scientific Reports, 2026

• DOI för Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial
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The Supportive Effect of Acarbose to Orlistat in Weight Management: A Randomized, Double‐Blind, Multiarm Phase 2 Trial

Holmbäck, Ulf; Grudén, Stefan; Kuusk, Sandra; Litorp, Helena et al.

Ingår i Obesity, s. 1855-1864, 2025

• DOI för The Supportive Effect of Acarbose to Orlistat in Weight Management: A Randomized, Double‐Blind, Multiarm Phase 2 Trial
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Packing and flow performance of binary adhesive mixtures for inhalation of different drug loads and their relationships to aerosolisation

Simonsson, Anna; Bramer, Tobias; Wimbush, Alex; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Packing and flow performance of binary adhesive mixtures for inhalation of different drug loads and their relationships to aerosolisation
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Assessment of the plasticity of dry granulated particles (mini-tablets) and its relationship to their tabletability

Tofiq, Maryam; Alderborn, Göran; Nordström, Josefina; Persson, Ann-Sofie

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Assessment of the plasticity of dry granulated particles (mini-tablets) and its relationship to their tabletability
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Packing, Flow and Aerosolization Properties of Binary Adhesive Mixtures Containing Micronized and Spray-Dried Drugs

Simonsson, Anna; Bunta Sundin, Nicklas; Bramer, Tobias; Wimbush, Alex et al.

Ingår i Pharmaceutics, 2026

• DOI för Packing, Flow and Aerosolization Properties of Binary Adhesive Mixtures Containing Micronized and Spray-Dried Drugs
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Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial

Holmbäck, Ulf; Grudén, Stefan; Kuusk, Sandra; Litorp, Helena et al.

Ingår i Scientific Reports, 2026

• DOI för Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial
• Ladda ner fulltext (pdf) av Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial

The Supportive Effect of Acarbose to Orlistat in Weight Management: A Randomized, Double‐Blind, Multiarm Phase 2 Trial

Holmbäck, Ulf; Grudén, Stefan; Kuusk, Sandra; Litorp, Helena et al.

Ingår i Obesity, s. 1855-1864, 2025

• DOI för The Supportive Effect of Acarbose to Orlistat in Weight Management: A Randomized, Double‐Blind, Multiarm Phase 2 Trial
• Ladda ner fulltext (pdf) av The Supportive Effect of Acarbose to Orlistat in Weight Management: A Randomized, Double‐Blind, Multiarm Phase 2 Trial

Packing and flow performance of binary adhesive mixtures for inhalation of different drug loads and their relationships to aerosolisation

Simonsson, Anna; Bramer, Tobias; Wimbush, Alex; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Packing and flow performance of binary adhesive mixtures for inhalation of different drug loads and their relationships to aerosolisation
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Assessment of the plasticity of dry granulated particles (mini-tablets) and its relationship to their tabletability

Tofiq, Maryam; Alderborn, Göran; Nordström, Josefina; Persson, Ann-Sofie

Ingår i International Journal of Pharmaceutics, 2025

• DOI för Assessment of the plasticity of dry granulated particles (mini-tablets) and its relationship to their tabletability
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A Comparative Analysis of the Pharmacodynamic and Pharmacokinetic Properties of 2 Controlled‐Release Formulations Versus a Marketed Orlistat Product

Grudén, Stefan; Forslund, Anders; Litorp, Helena; Kuusk, Sandra et al.

Ingår i Clinical Pharmacology in Drug Development, s. 304-310, 2025

• DOI för A Comparative Analysis of the Pharmacodynamic and Pharmacokinetic Properties of 2 Controlled‐Release Formulations Versus a Marketed Orlistat Product

The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering

Gråsjö, Johan; Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran et al.

Ingår i Powder Technology, 2025

• DOI för The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering
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The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Ingår i Powder Technology, 2025

• DOI för The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
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Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation

Simonsson, Anna; Bramer, Tobias; Wimbush, Alex; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, 2024

• DOI för Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation
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Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships

Persson, Ann-Sofie; Alderborn, Göran

Ingår i Pharmaceutical development and technology (Print), s. 509-519, 2023

• DOI för Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships
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Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran; Gråsjö, Johan

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 1-10, 2022

• DOI för Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness
• Ladda ner fulltext (pdf) av Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial

Holmbäck, Ulf; Gruden, Stefan; Litorp, Helena; Willhems, Daniel et al.

Ingår i Obesity, s. 2222-2232, 2022

• DOI för Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial
• Ladda ner fulltext (pdf) av Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial

Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. I. Experimental comparison

Persson, Ann-Sofie; Pazesh, Samaneh; Alderborn, Göran

Ingår i Pharmaceutical development and technology (Print), s. 319-330, 2022

• DOI för Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. I. Experimental comparison
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Deciphering the role of granule deformation and fragmentation for the tableting performance of some dry granulated powders

Tofiq, Maryam; Nordström, Josefina; Persson, Ann-Sofie; Alderborn, Göran

Ingår i Powder Technology, 2022

• DOI för Deciphering the role of granule deformation and fragmentation for the tableting performance of some dry granulated powders
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Effect of excipient properties and blend ratio on the compression properties of dry granulated particles prepared from microcrystalline cellulose and lactose

Tofiq, Maryam; Nordström, Josefina; Persson, Ann-Sofie; Alderborn, Göran

Ingår i Powder Technology, 2022

• DOI för Effect of excipient properties and blend ratio on the compression properties of dry granulated particles prepared from microcrystalline cellulose and lactose
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Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, 2022

• DOI för Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation
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Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran

Ingår i Pharmaceutics, 2021

• DOI för Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities
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Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Grudén, Stefan; Forslund, Anders; Alderborn, Göran; Söderhäll, Arvid et al.

Ingår i Clinical Pharmacology in Drug Development, s. 1242-1247, 2021

• DOI för Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.
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On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, 2021

• DOI för On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients
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Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity

Holmbäck, Ulf; Forslund, Anders; Gruden, Stefan; Alderborn, Göran et al.

Ingår i Obesity Science & Practice, s. 313-323, 2020

• DOI för Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
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Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern

Pazesh, Samaneh; Persson, Ann-Sofie; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, 2019

• DOI för Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern
• Ladda ner fulltext (pdf) av Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern

Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, s. 148-160, 2019

• DOI för Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model
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Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Jonsson, Henrik; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 74-81, 2019

• DOI för Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Jonsson, Henrik; Öhman-Mägi, Caroline; Alderborn, Göran; Isaksson, Per et al.

Ingår i International Journal of Pharmaceutics, s. 130-137, 2019

• DOI för Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Nordström, Josefina; Alderborn, Göran; Frenning, Göran

Ingår i International Journal of Pharmaceutics, s. 120-131, 2018

• DOI för Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, s. 143-156, 2018

• DOI för Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Determination of interfacial amorphicity in functional powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2018

Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Persson, Ann-Sofie; Ahmed, Hamzah; Velaga, Sitaram; Alderborn, Göran

Ingår i Journal of Pharmaceutical Sciences, s. 1920-1927, 2018

• DOI för Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Effect of milling on the plastic and the elastic stiffness of lactose particles

Pazesh, Samaneh; Persson, Ann-Sofie; Berggren, Jonas; Alderborn, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 138-145, 2018

• DOI för Effect of milling on the plastic and the elastic stiffness of lactose particles
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A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression

Persson, Ann-Sofie; Alderborn, Göran

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 28-37, 2018

• DOI för A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression
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Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

Tejedor, Maria Badal; Pazesh, Samaneh; Nordgren, Niklas; Schuleit, Michael et al.

Ingår i International Journal of Pharmaceutics, s. 140-147, 2018

• DOI för Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

Determination of Interfacial Amorphicity in Functional Powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Ingår i Langmuir, s. 920-926, 2017

• DOI för Determination of Interfacial Amorphicity in Functional Powders

Comminution-amorphisation relationships during ball milling of lactose at different milling conditions

Pazesh, Samaneh; Gråsjö, Johan; Berggren, Jonas; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, s. 215-227, 2017

• DOI för Comminution-amorphisation relationships during ball milling of lactose at different milling conditions
• Ladda ner fulltext (pdf) av Comminution-amorphisation relationships during ball milling of lactose at different milling conditions

Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Persson, Ann-Sofie; Nordström, Josefina; Frenning, Göran; Alderborn, Göran

Ingår i Chemical engineering research & design, s. 183-191, 2016

• DOI för Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Nordström, Josefina; Alderborn, Göran

Ingår i Journal of Pharmaceutical Sciences, s. 2029-2039, 2015

• DOI för The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

Hellrup, Joel; Alderborn, Göran; Mahlin, Denny

Ingår i Journal of Pharmaceutical Sciences, s. 3760-3769, 2015

• DOI för Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

Höckerfelt, Mina Heidarian; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, s. 326-333, 2014

• DOI för The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Mahmoodi, Foad; Klevan, Ingvild; Nordström, Josefina; Alderborn, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 295-299, 2013

• DOI för A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter
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Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

Pazesh, Samaneh; Höckerfelt, Mina Heidarian; Berggren, Jonas; Bramer, Tobias et al.

Ingår i Journal of Pharmaceutical Sciences, s. 4036-4045, 2013

• DOI för Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

A protocol for the classification of powder compression characteristics

Nordstrom, Josefina; Kievan, Ingvild; Alderborn, Göran

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 209-216, 2012

• DOI för A protocol for the classification of powder compression characteristics

An experimental evaluation of an effective medium based compaction equation

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 49-55, 2012

• DOI för An experimental evaluation of an effective medium based compaction equation
• Ladda ner fulltext (pdf) av An experimental evaluation of an effective medium based compaction equation

Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Salbu, Linda; Bauer-Brandl, Annette; Alderborn, Göran; Tho, Ingunn

Ingår i Pharmaceutical development and technology (Print), s. 333-343, 2012

• DOI för Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 283-290, 2011

• DOI för Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression
• Ladda ner fulltext (pdf) av Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Degree of compression as a potential process control tool of tablet tensile strength

Nordström, Josefina; Alderborn, Göran

Ingår i Pharmaceutical development and technology (Print), s. 599-608, 2011

• DOI för Degree of compression as a potential process control tool of tablet tensile strength

Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 199-209, 2011

• DOI för Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study
• Ladda ner fulltext (pdf) av Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Effect of lubrication on the distribution of force between spherical agglomerates during compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 69-74, 2010

• DOI för Effect of lubrication on the distribution of force between spherical agglomerates during compression
• Ladda ner fulltext (pdf) av Effect of lubrication on the distribution of force between spherical agglomerates during compression

Effect of preparation method on compactability of paracetamol granules and agglomerates

Fichtner, Frauke; Rasmuson, Åke; Ålander, Eva; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, s. 148-158, 2007

• DOI för Effect of preparation method on compactability of paracetamol granules and agglomerates

Drug release from compacted single inert matrix agglomerates

Fichtner, Frauke; Frenning, Göran; Alderborn, Göran

Ingår i Journal of Drug Delivery Science and Technology, s. 273-277, 2007

The use of extragranular disintegrants in multiple-unit tablet formulations: effect on compressibility, compactibility and disintegration

Adane, M.; Gebre-Mariam, T; Alderborn, Göran; Frenning, Göran

Ingår i Journal of drug delivery science and technology, s. 279-284, 2007

The influence of PVP incorporation on moisture-induced surface crystallization of amorphous spray-dried lactose particles

Mahlin, Denny; Berggren, Jonas; Gelius, Ulrik; Engström, Sven et al.

Ingår i International Journal of Pharmaceutics, s. 78-85, 2006

• DOI för The influence of PVP incorporation on moisture-induced surface crystallization of amorphous spray-dried lactose particles

Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

Nilsson, Martin; Frenning, Göran; Gråsjö, Johan; Alderborn, Göran et al.

Ingår i Journal of Physical Chemistry B, s. 20502-20506, 2006

• DOI för Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

Particle size distribution and evolution in tablet structure during and after compaction

Fichtner, Frauke; Rasmuson, Åke; Alderborn, Göran

Ingår i International Journal of Pharmaceutics, s. 211-225, 2005

• DOI för Particle size distribution and evolution in tablet structure during and after compaction

A new method for characterizing the release of drugs from single agglomerates

Frenning, Göran; Fichtner, Frauke; Alderborn, Göran

Ingår i Chemical Engineering Science, s. 3909-3918, 2005

• DOI för A new method for characterizing the release of drugs from single agglomerates

Evolution of distributions and spatial correlations of single-particle forces and stresses during compression of ductile granular materials.

Frenning, Göran; Alderborn, Göran

Ingår i Phys Rev E Stat Nonlin Soft Matter Phys, 2005

Particle size distribution and evolution in tablet structure during and after compaction.

Fichtner, Frauke; Rasmuson, Ake; Alderborn, Göran

Ingår i Int J Pharm, s. 211-25, 2005

Compression behaviour and tablet-forming ability of spray-dried amorphous composite particles.

Berggren, Jonas; Frenning, Göran; Alderborn, Göran

Ingår i Eur J Pharm Sci, s. 191-200, 2004

Effect of intragranular porosity on compression behaviour of and drug release from reservoir pellets

Tunón, Åsa; Gråsjö, Johan; Alderborn, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 333-344, 2003

• DOI för Effect of intragranular porosity on compression behaviour of and drug release from reservoir pellets

Water-induced charge transport in tablets of microcrystalline cellulose of varying density: Dielectric spectroscopy and transient current measurements

Nilsson, Martin; Alderborn, Göran; Strömme, Maria

Ingår i Chemical Physics, s. 159-165, 2003

• DOI för Water-induced charge transport in tablets of microcrystalline cellulose of varying density: Dielectric spectroscopy and transient current measurements

Tablets and compaction

Alderborn, G

Ingår i Aulton´s Pharmaceutics - The design and manufacture of medicines. 3rd ed., Churchill Livingstone, Edinburgh, 2007

Effect of pressure drop on blend state-dispersibility relationships of adhesive mixtures for inhalation

Rudén, Jonas; Alderborn, Göran; Frenning, Göran; Thalberg, Kyrre et al.

Packing, flow and aerosolisation properties of binary adhesive mixtures containing micronised and spray-dried drugs

Simonsson, Anna; Bunta Sundin, Nicklas; Bramer, Tobias; Wimbush, Alex et al.