Dan I. Andersson

The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing: Appendix files

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

2025

Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Ingår i Lancet Microbe, 2025

• DOI för Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
• Ladda ner fulltext (pdf) av Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Machine learning detection of heteroresistance in Escherichia coli

Guliaev, Andrei; Hjort, Karin; Rossi, Michele; Jonsson, Sofia et al.

Ingår i EBioMedicine, 2025

• DOI för Machine learning detection of heteroresistance in Escherichia coli
• Ladda ner fulltext (pdf) av Machine learning detection of heteroresistance in Escherichia coli

Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Nicoloff, Hervé; Hjort, Karin; Andersson, Dan I.; Wang, Helen

Ingår i Nature Communications, 2024

• DOI för Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance
• Ladda ner fulltext (pdf) av Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Pal, Ankita; Andersson, Dan I.

Ingår i Nature Communications, 2024

• DOI för Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
• Ladda ner fulltext (pdf) av Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Machine learning detection of heteroresistance in Escherichia coli

Guliaev, Andrei; Hjort, Karin; Rossi, Michele; Jonsson, Sofia et al.

Ingår i EBioMedicine, 2025

• DOI för Machine learning detection of heteroresistance in Escherichia coli
• Ladda ner fulltext (pdf) av Machine learning detection of heteroresistance in Escherichia coli

Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Nicoloff, Hervé; Hjort, Karin; Andersson, Dan I.; Wang, Helen

Ingår i Nature Communications, 2024

• DOI för Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance
• Ladda ner fulltext (pdf) av Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Pal, Ankita; Andersson, Dan I.

Ingår i Nature Communications, 2024

• DOI för Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
• Ladda ner fulltext (pdf) av Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes

Heidarian, Sheida; Guliaev, Andrei; Nicoloff, Hervé; Hjort, Karin et al.

Ingår i PLoS biology, 2024

• DOI för High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes
• Ladda ner fulltext (pdf) av High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes

Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Babina, Arianne M.; Kirsebom, Leif; Andersson, Dan I.

Ingår i RNA, s. 977-991, 2024

• DOI för Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations
• Ladda ner fulltext (pdf) av Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

Fatsis-Kavalopoulos, Nikos; Sánchez-Hevia, Dione; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 2394-2396, 2024

• DOI för Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)
• Ladda ner fulltext (pdf) av Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

The strength of interspecies interaction in a microbial community determines its susceptibility to invasion

Muzafar, Suraya; Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Ingår i PLoS biology, 2024

• DOI för The strength of interspecies interaction in a microbial community determines its susceptibility to invasion
• Ladda ner fulltext (pdf) av The strength of interspecies interaction in a microbial community determines its susceptibility to invasion

Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes

Babiker, Ahmed; Lohsen, Sarah; Van Riel, Julia; Hjort, Karin et al.

Ingår i JAC - Antimicrobial Resistance, 2024

• DOI för Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes
• Ladda ner fulltext (pdf) av Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes

Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Ingår i Microbiology Spectrum, 2024

• DOI för Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids
• Ladda ner fulltext (pdf) av Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Within-species variability of antibiotic interactions in Gram-negative bacteria

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikos et al.

Ingår i mBio, 2024

• DOI för Within-species variability of antibiotic interactions in Gram-negative bacteria
• Ladda ner fulltext (pdf) av Within-species variability of antibiotic interactions in Gram-negative bacteria

Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Ingår i Scientific Reports, 2024

• DOI för Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
• Ladda ner fulltext (pdf) av Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism

Warsi, Omar M.; Upterworth, Lina M.; Breidenstein, Annika; Lustig, Ulrika et al.

Ingår i mBio, 2024

• DOI för Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism
• Ladda ner fulltext (pdf) av Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism

Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance

Levin, Bruce R.; Berryhill, Brandon A.; Gil-Gil, Teresa; Manuel, Joshua A. et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance
• Ladda ner fulltext (pdf) av Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance

Rescue of Escherichia coli auxotrophy by de novo small proteins

Babina, Arianne M.; Surkov, Serhiy; Ye, Weihua; Jerlström-Hultqvist, Jon et al.

Ingår i eLIFE, 2023

• DOI för Rescue of Escherichia coli auxotrophy by de novo small proteins
• Ladda ner fulltext (pdf) av Rescue of Escherichia coli auxotrophy by de novo small proteins

Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

Fait, Anaelle; Andersson, Dan I.; Ingmer, Hanne

Ingår i Current Biology, 2023

• DOI för Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution
• Ladda ner fulltext (pdf) av Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities

Warsi, Omar M.; Gedda, Lars; Edwards, Katarina; Andersson, Dan I.

Ingår i FEMS Microbiology Ecology, 2023

• DOI för Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities
• Ladda ner fulltext (pdf) av Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities

Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations

Pereira, Catia; Warsi, Omar M.; Andersson, Dan I.

Ingår i Molecular biology and evolution, 2023

• DOI för Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations
• Ladda ner fulltext (pdf) av Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations

Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli

Nair, Ramith R.; Andersson, Dan I.

Ingår i Communications Biology, 2023

• DOI för Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli
• Ladda ner fulltext (pdf) av Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli

Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

Howard-Anderson, Jessica; Davis, Michelle; Page, Alexander M.; Bower, Chris W. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 793-798, 2022

• DOI för Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies

Zaborskyte, Greta; Wistrand-Yuen, Erik; Hjort, Karin; Andersson, Dan I. et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2022

• DOI för Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies
• Ladda ner fulltext (pdf) av Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies

Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Hjort, Karin; Fermer, Elin; Tang, Po-Cheng; Andersson, Dan I.

Ingår i mBio, 2022

• DOI för Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

Fatsis-Kavalopoulos, Nikos; Roelofs, Lex; Andersson, Dan I.

Ingår i EBioMedicine, 2022

• DOI för Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates
• Ladda ner fulltext (pdf) av Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Tang, Po-Cheng; Eriksson, Olle; Sjögren, Josefin; Fatsis-Kavalopoulos, Nikos et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2022

• DOI för A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms
• Ladda ner fulltext (pdf) av A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

Ingår i PLoS biology, 2022

• DOI för Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline
• Ladda ner fulltext (pdf) av Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline

The highly dynamic nature of bacterial heteroresistance impairs its clinical detection

Pereira, Cátia; Larsson, Jimmy; Hjort, Karin; Elf, Johan et al.

Ingår i Communications Biology, 2021

• DOI för The highly dynamic nature of bacterial heteroresistance impairs its clinical detection
• Ladda ner fulltext (pdf) av The highly dynamic nature of bacterial heteroresistance impairs its clinical detection

Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family

Guo, Xiaohu; Söderholm, Annika; Kanchugal Puttaswamy, Sandesh; Isaksen, Geir V et al.

Ingår i eLIFE, 2021

• DOI för Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family
• Ladda ner fulltext (pdf) av Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family

The chemotherapeutic drug methotrexate selects for antibiotic resistance

Gudmundsdottir, Jonina S.; Fredheim, Elizabeth G. A.; Koumans, Catharina I. M.; Hegstad, Joachim et al.

Ingår i EBioMedicine, 2021

• DOI för The chemotherapeutic drug methotrexate selects for antibiotic resistance
• Ladda ner fulltext (pdf) av The chemotherapeutic drug methotrexate selects for antibiotic resistance

An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance

Ancillotti, Mirko; Eriksson, Stefan; Godskesen, Tove; Andersson, Dan I. et al.

Ingår i Public Health Ethics, s. 1-11, 2021

• DOI för An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance
• Ladda ner fulltext (pdf) av An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance

Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Atterby, Clara; Nykvist, Marie; Lustig, Ulrika; Andersson, Dan I. et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2021

• DOI för Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Mechanisms and therapeutic potential of collateral sensitivity to antibiotics

Roemhild, Roderich; Andersson, Dan I.

Ingår i PLoS Pathogens, 2021

• DOI för Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
• Ladda ner fulltext (pdf) av Mechanisms and therapeutic potential of collateral sensitivity to antibiotics

A novel type of colistin resistance genes selected from random sequence space

Knopp, Michael; Babina, Arianne M.; Gudmundsdottir, Jonina S.; Douglass, Martin et al.

Ingår i PLOS Genetics, 2021

• DOI för A novel type of colistin resistance genes selected from random sequence space
• Ladda ner fulltext (pdf) av A novel type of colistin resistance genes selected from random sequence space

A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Rao, Komal Umashankar; Henderson, Domhnall Iain; Krishnan, Nitya; Puthia, Manoj et al.

Ingår i Scientific Reports, 2021

• DOI för A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy
• Ladda ner fulltext (pdf) av A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Metabolic fitness landscapes predict the evolution of antibiotic resistance

Pinheiro, Fernanda; Warsi, Omar M.; Andersson, Dan I.; Laessig, Michael

Ingår i Nature Ecology & Evolution, s. 677-687, 2021

• DOI för Metabolic fitness landscapes predict the evolution of antibiotic resistance

Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene

Warsi, Omar; Knopp, Michael; Surkov, Serhiy; Jerlström-Hultqvist, Jon et al.

Ingår i Molecular biology and evolution, s. 1329-1341, 2020

• DOI för Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene
• Ladda ner fulltext (pdf) av Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene

Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence

Lundin, Erik; Näsvall, Joakim; Andersson, Dan I.

Ingår i Frontiers in Microbiology, 2020

• DOI för Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence
• Ladda ner fulltext (pdf) av Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence

Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA

Knöppel, Anna; Andersson, Dan I; Näsvall, Joakim

Ingår i Frontiers in Microbiology, 2020

• DOI för Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA
• Ladda ner fulltext (pdf) av Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA

CombiANT: Antibiotic interaction testing made easy

Fatsis-Kavalopoulos, Nikos; Römhild, Roderich; Tang, Po-Cheng; Kreuger, Johan et al.

Ingår i PLoS biology, 2020

• DOI för CombiANT: Antibiotic interaction testing made easy
• Ladda ner fulltext (pdf) av CombiANT: Antibiotic interaction testing made easy

Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment

Hjort, Karin; Jurén, Pontus; Toro, Juan Carlos; Hoffner, Sven et al.

Ingår i Journal of Infectious Diseases, s. 1011-1020, 2020

• DOI för Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment
• Ladda ner fulltext (pdf) av Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment

Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment

Ancillotti, Mirko; Eriksson, Stefan; Andersson, Dan I.; Godskesen, Tove et al.

Ingår i International Journal of Antimicrobial Agents, 2020

• DOI för Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment
• Ladda ner fulltext (pdf) av Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment

Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics

Blanco, Paula; Hjort, Karin; Martinez, Jose L.; Andersson, Dan I

Ingår i mSphere, 2020

• DOI för Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics
• Ladda ner fulltext (pdf) av Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics

Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli

Puértolas-Balint, Fabiola; Warsi, Omar; Linkevicius, Marius; Tang, Po-Cheng et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 300-308, 2020

• DOI för Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli
• Ladda ner fulltext (pdf) av Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli

Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin

Römhild, Roderich; Linkevicius, Marius; Andersson, Dan I

Ingår i PLoS biology, 2020

• DOI för Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin
• Ladda ner fulltext (pdf) av Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin

A portable epigenetic switch for bistable gene expression in bacteria

Olivenza, David R.; Nicoloff, Hervé; Antonia Sanchez-Romero, Maria; Cota, Ignacio et al.

Ingår i Scientific Reports, 2019

• DOI för A portable epigenetic switch for bistable gene expression in bacteria
• Ladda ner fulltext (pdf) av A portable epigenetic switch for bistable gene expression in bacteria

Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase

Rosenkilde, Carola E. H.; Munck, Christian; Porse, Andreas; Linkevicius, Marius et al.

Ingår i Nature Communications, 2019

• DOI för Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase
• Ladda ner fulltext (pdf) av Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase

Inhibition of translation termination by small molecules targeting ribosomal release factors

Ge, Xueliang; Oliveira, Ana; Hjort, Karin; Bergfors, Terese et al.

Ingår i Scientific Reports, 2019

• DOI för Inhibition of translation termination by small molecules targeting ribosomal release factors
• Ladda ner fulltext (pdf) av Inhibition of translation termination by small molecules targeting ribosomal release factors

Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli

Thulin, Elisabeth; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, 2019

• DOI för Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli
• Ladda ner fulltext (pdf) av Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli

De Novo Emergence of Peptides That Confer Antibiotic Resistance

Knopp, Michael; Gudmundsdottir, Jonina S.; Nilsson, Tobias; Konig, Finja et al.

Ingår i mBio, 2019

• DOI för De Novo Emergence of Peptides That Confer Antibiotic Resistance
• Ladda ner fulltext (pdf) av De Novo Emergence of Peptides That Confer Antibiotic Resistance

Selection for novel metabolic capabilities in Salmonella enterica

Warsi, Omar M.; Lundin, Erik; Lustig, Ulrika; Näsvall, Joakim et al.

Ingår i Evolution, s. 990-1000, 2019

• DOI för Selection for novel metabolic capabilities in Salmonella enterica
• Ladda ner fulltext (pdf) av Selection for novel metabolic capabilities in Salmonella enterica

The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification

Nicoloff, Hervé; Hjort, Karin; Levin, Bruce R.; Andersson, Dan I

Ingår i Nature Microbiology, s. 504-514, 2019

• DOI för The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Jerlström-Hultqvist, Jon; Warsi, Omar; Söderholm, Annika; Knopp, Michael et al.

Ingår i Nature Ecology & Evolution, s. 1321-1330, 2018

• DOI för A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia.

Bonnedah, Jonas; Berg, Charlotte; Andersson, Dan I; Söderlund, Robert et al.

Ingår i Infection Ecology & Epidemiology, 2018

• DOI för Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia.
• Ladda ner fulltext (pdf) av Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia.

Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection

Sandegren, Linus; Stedt, Johan; Lustig, Ulrika; Bonnedahl, Jonas et al.

Ingår i Environmental Microbiology Reports, s. 576-582, 2018

• DOI för Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection
• Ladda ner fulltext (pdf) av Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection

Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation

Warsi, Omar M.; Andersson, Dan I; Dykhuizen, Daniel E.

Ingår i BMC Evolutionary Biology, 2018

• DOI för Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation
• Ladda ner fulltext (pdf) av Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation

Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica

Knöppel, Anna; Knopp, Michael; Albrecht, Lisa M; Lundin, Erik et al.

Ingår i Frontiers in Microbiology, 2018

• DOI för Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica
• Ladda ner fulltext (pdf) av Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica

Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions

Ancillotti, Mirko; Eriksson, Stefan; Veldwijk, Jorien; Nihlén Fahlquist, Jessica et al.

Ingår i BMC Public Health, 2018

• DOI för Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions
• Ladda ner fulltext (pdf) av Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions

Evolution of high-level resistance during low-level antibiotic exposure

Wistrand-Yuen, Erik; Knopp, Michael; Hjort, Karin; Koskiniemi, Sanna et al.

Ingår i Nature Communications, 2018

• DOI för Evolution of high-level resistance during low-level antibiotic exposure
• Ladda ner fulltext (pdf) av Evolution of high-level resistance during low-level antibiotic exposure

No beneficial fitness effects of random peptides

Knopp, Michael; Andersson, Dan I

Ingår i Nature Ecology & Evolution, s. 1046-1047, 2018

• DOI för No beneficial fitness effects of random peptides
• Ladda ner fulltext (pdf) av No beneficial fitness effects of random peptides

Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.

Roemhild, Roderich; Gokhale, Chaitanya S; Dirksen, Philipp; Blake, Christopher et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 9767-9772, 2018

• DOI för Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.
• Ladda ner fulltext (pdf) av Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.

Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA

Lundin, Erik; Tang, Po-Cheng; Guy, Lionel; Näsvall, Joakim et al.

Ingår i Molecular biology and evolution, s. 704-718, 2018

• DOI för Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA
• Ladda ner fulltext (pdf) av Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA

Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

Zykov, Ilya Nikolaevich; Samuelsen, Orjan; Jakobsen, Lotte; Smabrekke, Lars et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2018

• DOI för Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model
• Ladda ner fulltext (pdf) av Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

Predictable Phenotypes of Antibiotic Resistance Mutations

Knopp, Michael; Andersson, Dan I

Ingår i mBio, 2018

• DOI för Predictable Phenotypes of Antibiotic Resistance Mutations

Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Khan, David; Lagerbäck, Pernilla; Malmberg, Christer; Kristoffersson, Anders et al.

Ingår i International Journal of Antimicrobial Agents, s. 399-406, 2018

• DOI för Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects

Lind, Peter A.; Arvidsson, Lars; Berg, Otto; Andersson, Dan I.

Ingår i Molecular biology and evolution, s. 408-418, 2017

• DOI för Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects

Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria

Näsvall, Joakim; Knöppel, Anna; Andersson, Dan I.

Ingår i Nucleic Acids Research, 2017

• DOI för Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria
• Ladda ner fulltext (pdf) av Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria

Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment

Gumpert, Heidi; Kubicek-Sutherland, Jessica Z.; Porse, Andreas; Karami, Nahid et al.

Ingår i Frontiers in Microbiology, 2017

• DOI för Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment
• Ladda ner fulltext (pdf) av Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment

Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides

Kubicek-Sutherland, Jessica Z.; Lofton, Hava; Vestergaard, Martin; Hjort, Karin et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 115-127, 2017

• DOI för Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides
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Selection and Transmission of Antibiotic-Resistant Bacteria

Andersson, Dan I; Hughes, Diarmaid

Ingår i Microbiology Spectrum, 2017

• DOI för Selection and Transmission of Antibiotic-Resistant Bacteria

Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Nielsen, Elisabet I.; Khan, David D.; Cao, Sha; Lustig, Ulrika et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 3108-3116, 2017

• DOI för Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.

Thulin, Elisabeth; Eriksson, Måns; Andersson, Dan I

Ingår i EBioMedicine, s. 111-118, 2017

• DOI för Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.
• Ladda ner fulltext (pdf) av Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.

Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Newton, Matilda S.; Guo, Xiaohu; Söderholm, Annika; Näsvall, Joakim et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 4727-4732, 2017

• DOI för Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Evolution of antibiotic resistance without antibiotic exposure

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Ingår i Antimicrobial Agents and Chemotherapy, 2017

• DOI för Evolution of antibiotic resistance without antibiotic exposure
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Genome Dynamics of Escherichia coli during Antibiotic Treatment: Transfer, Loss, and Persistence of Genetic Elements In situ of the Infant Gut

Porse, Andreas; Gumpert, Heidi; Kubicek-Sutherland, Jessica Z.; Karami, Nahid et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2017

• DOI för Genome Dynamics of Escherichia coli during Antibiotic Treatment: Transfer, Loss, and Persistence of Genetic Elements In situ of the Infant Gut
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Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides

Malik, Sohaib Zafar; Linkevicius, Marius; Göransson, Ulf; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, 2017

• DOI för Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides
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Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Baltekin, Özden; Boucharin, Alexis; Tano, Eva; Andersson, Dan I et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 9170-9175, 2017

• DOI för Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

Kacar, Betül; Garmendia, Eva; Tuncbag, Nurcan; Andersson, Dan I et al.

Ingår i mBio, 2017

• DOI för Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica

Hjort, Karin; Nicoloff, Hervé; Andersson, Dan I.

Ingår i Molecular Microbiology, s. 274-289, 2016

• DOI för Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica
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Bacterial Resistance To A Cyclic Antimicrobial Peptide

Malik, Sohaib Zafar; Göransson, Ulf; Andersson, Dan I

Ingår i Journal of Peptide Science, 2016

• DOI för Bacterial Resistance To A Cyclic Antimicrobial Peptide

Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Adler, Marlen; Anjum, Mehreen; Andersson, Dan I.; Sandegren, Linus

Ingår i Journal of Antimicrobial Chemotherapy, s. 1188-1198, 2016

• DOI för Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase

Freihofer, Pietro; Akbergenov, Rashid; Teo, Youjin; Juskeviciene, Reda et al.

Ingår i RNA, s. 1836-1843, 2016

• DOI för Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase

Potential of tetracycline resistance proteins to evolve tigecycline resistance

Linkevicius, Marius; Sandegren, Linus; Andersson, Dan I.

Ingår i Antimicrobial Agents and Chemotherapy, s. 789-796, 2016

• DOI för Potential of tetracycline resistance proteins to evolve tigecycline resistance
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Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline

Linkevicius, Marius; Anderssen, Jytte Mark; Sandegren, Linus; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1307-1313, 2016

• DOI för Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline

Compensating the fitness costs of synonymous mutations

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Ingår i Molecular biology and evolution, s. 1461-1477, 2016

• DOI för Compensating the fitness costs of synonymous mutations
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Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes

Nicoloff, Herve; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 100-110, 2016

• DOI för Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes

Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

Knopp, Michael; Andersson, Dan I.

Ingår i Molecular biology and evolution, s. 3252-3263, 2015

• DOI för Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections

Mezger, Anja; Gullberg, Erik; Goransson, Jenny; Zorzet, Anna et al.

Ingår i Journal of Clinical Microbiology, s. 425-432, 2015

• DOI för A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections
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Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Thulin, Elisabeth; Sundqvist, Martin; Andersson, Dan I.

Ingår i Antimicrobial Agents and Chemotherapy, s. 1723-1732, 2015

• DOI för Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Fitness of Salmonella mutants resistant to antimicrobial peptides

Lofton, Hava; Anwar, Naeem; Rhen, Mikael; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 432-440, 2015

• DOI för Fitness of Salmonella mutants resistant to antimicrobial peptides

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Khan, David D.; Lagerbäck, Pernilla; Cao, Sha; Lustig, Ulrika et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 3051-3060, 2015

• DOI för A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase

Chen, Yang; Näsvall, Joakim; Wu, Shiying; Andersson, Dan I. et al.

Ingår i Acta Crystallographica Section D, s. 2267-2277, 2015

• DOI för Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase
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High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms

Adler, Marlen; Anjum, Mehreen; Berg, Otto; Andersson, Dan I. et al.

Ingår i Molecular biology and evolution, s. 1526-1535, 2014

• DOI för High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms

Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

Knöppel, Anna; Lind, Peter A.; Lustig, Ulrika; Näsvall, Joakim et al.

Ingår i Molecular biology and evolution, s. 1220-1227, 2014

• DOI för Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium

Koskiniemi, Sanna; Garza-Sanchez, Fernando; Sandegren, Linus; Webb, Julia S. et al.

Ingår i PLOS Genetics, 2014

• DOI för Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium
• Ladda ner fulltext (pdf) av Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium

Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica

Sun, Song; Selmer, Maria; Andersson, Dan I.

Ingår i PLOS ONE, 2014

• DOI för Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica
• Ladda ner fulltext (pdf) av Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica

Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals

Gullberg, Erik; Albrecht, Lisa M; Karlsson, Christoffer; Sandegren, Linus et al.

Ingår i mBio, 2014

• DOI för Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals

Characterization of Resitant Mutants Points Towards Mechanism of Action of Cyclotides

Malik, Sohaib Zafar; Andersson, Dan I.; Göransson, Ulf

Ingår i Journal of Peptide Science, 2014

Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice

Koskiniemi, Sanna; Gibbons, Henry S.; Sandegren, Linus; Anwar, Naeem et al.

Ingår i PLOS ONE, 2013

• DOI för Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice
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Fitness Costs of Synonymous Mutations in the rpsT Gene Can Be Compensated by Restoring mRNA Base Pairing

Lind, Peter A.; Andersson, Dan I.

Ingår i PLOS ONE, 2013

• DOI för Fitness Costs of Synonymous Mutations in the rpsT Gene Can Be Compensated by Restoring mRNA Base Pairing
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Evolution of Broad Spectrum beta-Lactam Resistance in an Engineered Metallo-beta-lactamase

Sun, Song; Zhang, Wei; Mannervik, Bengt; Andersson, Dan I.

Ingår i Journal of Biological Chemistry, s. 2314-2324, 2013

• DOI för Evolution of Broad Spectrum beta-Lactam Resistance in an Engineered Metallo-beta-lactamase

Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones

Lofton Tomenius, Hava; Pränting, Maria; Thulin, Elisabeth; Andersson, Dan I.

Ingår i PLOS ONE, 2013

• DOI för Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones
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Lon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance

Nicoloff, Hervé; Andersson, Dan I.

Ingår i Molecular Microbiology, s. 1233-1248, 2013

• DOI för Lon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance

Mechanisms and fitness costs of tigecycline resistance in Escherichia coli

Linkevicius, Marius; Sandegren, Linus; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 2809-2819, 2013

• DOI för Mechanisms and fitness costs of tigecycline resistance in Escherichia coli

Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli

Adler, Marlen; Anjum, Mehreen; Andersson, Dan I.; Sandegren, Linus

Ingår i Journal of Antimicrobial Chemotherapy, s. 51-59, 2013

• DOI för Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli

Selection-driven genome reduction in bacteria

Koskiniemi, Sanna; Sun, Song; Berg, Otto; Andersson, Dan I.

Ingår i PLOS genetics, 2012

• DOI för Selection-driven genome reduction in bacteria
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Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak

Sandegren, Linus; Linkevicius, Marius; Lytsy, Birgitta; Åsa, Melhus et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 74-83, 2012

• DOI för Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak

Genome-Wide Detection of Spontaneous Chromosomal Rearrangements in Bacteria

Sun, Song; Ke, Rongqin; Hughes, Diarmaid; Nilsson, Mats et al.

Ingår i PLOS ONE, 2012

• DOI för Genome-Wide Detection of Spontaneous Chromosomal Rearrangements in Bacteria
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Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Zorzet, Anna; Andersen, Jytte Mark; Nilsson, Annika I; Møller, Niels Frimodt et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1835-1842, 2012

• DOI för Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses

Roth, John R.; Andersson, Dan I.

Ingår i Cell, s. 671-672, 2012

• DOI för Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses

Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Näsvall, Joakim; Sun, Lei; Roth, John R.; Andersson, Dan I.

Ingår i Science, s. 384-387, 2012

• DOI för Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Selection of resistance at lethal and non-lethal antibiotic concentrations

Hughes, Diarmaid; Andersson, Dan I

Ingår i Current Opinion in Microbiology, s. 555-560, 2012

• DOI för Selection of resistance at lethal and non-lethal antibiotic concentrations

Evolution of antibiotic resistance at non-lethal drug concentrations.

Andersson, Dan I; Hughes, Diarmaid

Ingår i Drug resistance updates, s. 162-172, 2012

• DOI för Evolution of antibiotic resistance at non-lethal drug concentrations.

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Pavlov, Michael Y.; Zorzet, Anna; Andersson, Dan I.; Ehrenberg, Måns

Ingår i EMBO Journal, s. 289-301, 2011

• DOI för Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

Gullberg, Erik; Cao, Sha; Berg, Otto G.; Ilbäck, Carolina et al.

Ingår i PLoS pathogens, 2011

• DOI för Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

Activation of cryptic aminoglycoside resistance in Salmonella enterica

Koskiniemi, Sanna; Pränting, Maria; Gullberg, Erik; Näsvall, Joakim et al.

Ingår i Molecular Microbiology, s. 1464-1478, 2011

• DOI för Activation of cryptic aminoglycoside resistance in Salmonella enterica

Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation

Pränting, Maria; Andersson, Dan I.

Ingår i Molecular Microbiology, s. 305-315, 2011

• DOI för Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation

Evolving promiscuously

Andersson, Dan I.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 1199-1200, 2011

• DOI för Evolving promiscuously

PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides

Zetterberg, Malin M.; Reijmar, Karin; Pränting, Maria; Engström, Åke et al.

Ingår i Journal of Controlled Release, s. 323-328, 2011

• DOI för PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides
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Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Luis Martinez, Jose; Baquero, Fernando; Andersson, Dan I.

Ingår i Current opinion in pharmacology (Print), s. 439-445, 2011

• DOI för Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment

Mariam, Solomon H.; Werngren, Jim; Aronsson, Joakim; Hoffner, Sven et al.

Ingår i PLOS ONE, 2011

Compensatory gene amplification restores fitness after inter-species gene replacements

Lind, Peter A; Tobin, Christina; Berg, Otto G; Kurland, Charles G et al.

Ingår i Molecular Microbiology, s. 1078-1089, 2010

• DOI för Compensatory gene amplification restores fitness after inter-species gene replacements

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

Zorzet, Anna; Pavlov, Michael; Nilsson, Annika; Ehrenberg, Måns et al.

Ingår i Molecular Microbiology, s. 1299-1313, 2010

• DOI för Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance
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Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Tobin, Christina; Mandava, Chandra Sekhar; Ehrenberg, Måns; Andersson, Dan I et al.

Ingår i Journal of Molecular Biology, s. 767-776, 2010

• DOI för Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

Pränting, Maria; Lööv, Camilla; Burman, Robert; Göransson, Ulf et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 1964-1971, 2010

• DOI för The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

Mutational robustness of ribosomal protein genes

Lind, Peter A.; Berg, Otto G.; Andersson, Dan I

Ingår i Science, s. 825-827, 2010

• DOI för Mutational robustness of ribosomal protein genes

Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2

Pränting, Maria; Andersson, Dan I

Ingår i Journal of Antimicrobial Chemotherapy, s. 876-887, 2010

• DOI för Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2

Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor

Huitric, E.; Verhasselt, P.; Koul, A.; Andries, K. et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 1022-1028, 2010

• DOI för Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor

Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Paulander, Wilhelm; Andersson, Dan I.; Maisnier-Patin, Sophie

Ingår i Genetics, s. 305-312, 2010

• DOI för Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

The Tandem Inversion Duplication in Salmonella enterica: Selection Drives Unstable Precursors to Final Mutation Types

Kugelberg, Elisabeth; Kofoid, Eric; Andersson, Dan I.; Lu, Yong et al.

Ingår i Genetics, s. 65-80, 2010

• DOI för The Tandem Inversion Duplication in Salmonella enterica: Selection Drives Unstable Precursors to Final Mutation Types

Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

Sundqvist, Martin; Geli, Patricia; Andersson, Dan I.; Sjölund-Karlsson, M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 350-360, 2010

• DOI för Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

Effect of the translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium

Koskiniemi, Sanna; Hughes, Diarmaid; Andersson, Dan I

Ingår i Genetics, s. 783-795, 2010

• DOI för Effect of the translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium

Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

Shcherbakov, Dmitri; Akbergenov, Rashid; Matt, Tanja; Sander, Peter et al.

Ingår i Molecular Microbiology, s. 830-40, 2010

• DOI för Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

Sun, Song; Berg, Otto G; Andersson, Dan I; Roth, John R

Ingår i Genetics, s. 1183-1195, 2009

• DOI för Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium

Sun, Song; Negrea, Aurel; Rhen, Mikael; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, s. 2298-2305, 2009

• DOI för Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium

Evolution of new gene functions: simulation and analysis of the amplification model.

Pettersson, Mats E.; Sun, Song; Andersson, Dan I.; Berg, Otto G

Ingår i Genetica, s. 309-324, 2009

• DOI för Evolution of new gene functions: simulation and analysis of the amplification model.

A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

Geli, Patricia; Andersson, Mikael; Svensson, Åke; Andersson, Dan I

Ingår i Journal of Theoretical Biology, s. 58-64, 2009

• DOI för A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)

Paulander, Wilhelm; Maisnier-Patin, Sophie; Andersson, Dan I

Ingår i Genetics, s. 539-546, 2009

• DOI för The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)

Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium

Koskiniemi, Sanna; Andersson, Dan I

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 10248-10253, 2009

• DOI för Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium

The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15

Lytsy, Birgitta; Sandegren, Linus; Tano, Eva; Torell, Erik et al.

Ingår i Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), s. 302-8, 2008

• DOI för The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15

Whole-genome mutational biases in bacteria

Lind, Peter A.; Andersson, Dan I.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 17878-83, 2008

• DOI för Whole-genome mutational biases in bacteria

Restored fitness leads to long-term persistence of resistant Bacteroides strains in the human intestine

Löfmark, Sonja; Jernberg, Cecilia; Billström, Hanna; Andersson, Dan I. et al.

Ingår i Anaerobe, s. 157-160, 2008

• DOI för Restored fitness leads to long-term persistence of resistant Bacteroides strains in the human intestine

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

Sandegren, Linus; Lindqvist, Anton; Kahlmeter, Gunnar; Andersson, Dan I

Ingår i Journal of Antimicrobial Chemotherapy, s. 495-503, 2008

• DOI för Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2

Pränting, Maria; Negrea, Aurel; Rhen, Mikael; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, s. 2734-2741, 2008

• DOI för Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2

Shrinking Bacterial Genomes: Former skeptics recognize that the genomes of microbial parasites and symbionts are subject to dynamic downsizing

Andersson, Dan I

Ingår i Microbe, s. 124-130, 2008

Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Paulander, Wilhelm; Pennhag, Alexandra; Andersson, Dan I.; Maisnier-Patin, Sophie

Ingår i Antimicrobial Agents and Chemotherapy, s. 766-769, 2007

• DOI för Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Ohno's dilemma: evolution of new genes under continuous selection

Bergthorsson, Ulfar; Andersson, Dan I.; Roth, John R.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 17004-17009, 2007

• DOI för Ohno's dilemma: evolution of new genes under continuous selection

Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium

Paulander, Wilhelm; Maisnier-Patin, Sophie; Andersson, Dan I.

Ingår i Molecular Microbiology, s. 1038-1048, 2007

• DOI för Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium

Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Wiuff, Camilla; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 254-263, 2007

• DOI för Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Maisnier-Patin, S; Paulander, W; Pennhag, A; Andersson, Dan I.

Ingår i Journal of Molecular Biology, s. 207-215, 2007

• DOI för Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes

Nilsson, Annika I.; Zorzet, Anna; Kanth, Anna; Dahlström, Sabina et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 6976-6981, 2006

• DOI för Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes

Multiple pathways of selected gene amplification during adaptive mutation

Kugelberg, Elisabeth; Kofoid, Eric; Reams, Andrew B.; Andersson, Dan I. et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 17319-17324, 2006

• DOI för Multiple pathways of selected gene amplification during adaptive mutation

The biological cost of mutational antibiotic resistance: any practical conclusions?

Andersson, Dan I

Ingår i Curr Opin Microbiol, s. 461-5, 2006

Origin of mutations under selection: the adaptive mutation controversy.

Roth, John R; Kugelberg, Elisabeth; Reams, Andrew B; Kofoid, Eric et al.

Ingår i Annu Rev Microbiol, s. 477-501, 2006

Genomic buffering mitigates the effects of deleterious mutations in bacteria

Maisnier-Patin, Sophie; Roth, John; Fredriksson, Åsa; Nyström, Thomas et al.

Ingår i Nature Genetics, s. 1376-1379, 2005

• DOI för Genomic buffering mitigates the effects of deleterious mutations in bacteria

Slow genetic divergence of Helicobacter pylori strains during long-term colonization

Lundin, Annelie; Björkholm, Britta; Kupershmidt, Ilya; Unemo, Magnus et al.

Ingår i Infection and Immunity, s. 4818-4822, 2005

• DOI för Slow genetic divergence of Helicobacter pylori strains during long-term colonization

Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes

Kugelberg, Elisabeth; Norström, Tobias; Petersen, Thomas K; Duvold, Tore et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 3435-3441, 2005

• DOI för Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes

Persistence of resistant Staphylococcus epidermidis after single course of clarithromycin

Sjölund, Maria; Tano, Eva; Blaser, Martin J; Andersson, Dan I et al.

Ingår i Emerging Infectious Diseases, s. 1389-1393, 2005

Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa

Kugelberg, Elisabeth; Löfmark, Sonja; Wretlind, Bengt; Andersson, Dan I

Ingår i Journal of Antimicrobial Chemotherapy, s. 22-30, 2005

• DOI för Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa

Bacterial genome size reduction by experimental evolution

Nilsson, A I; Koskiniemi, Sanna; Eriksson, S; Kugelberg, E et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 12112-12116, 2005

• DOI för Bacterial genome size reduction by experimental evolution

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli

Olofsson, Sara K.; Geli, Patricia; Andersson, Dan I.; Cars, Otto

Ingår i Antimicrobial Agents and Chemotherapy, s. 5081-5091, 2005

Drug resistance and fitness in Mycobacterium tuberculosis infection.

Bottger, Erik C; Pletschette, Michel; Andersson, Dan

Ingår i J Infect Dis, s. 823-4; author reply 824, 2005

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli.

Olofsson, Sara K; Geli, Patricia; Andersson, Dan I; Cars, Otto

Ingår i Antimicrob Agents Chemother, s. 5081-91, 2005

Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Roth, John R; Andersson, Dan I

Ingår i Journal of Bacteriology, s. 4855-4860, 2004

• DOI för Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Rebuttal: adaptive mutation in Escherichia coli (Foster)

Roth, John R; Andersson, Dan I

Ingår i Journal of Bacteriology, s. 4854-4854, 2004

• DOI för Rebuttal: adaptive mutation in Escherichia coli (Foster)

Rebuttal: adaptive point mutation (Rosenberg and Hastings)

Roth, John R; Andersson, Dan I

Ingår i Journal of Bacteriology, s. 4844, 2004

• DOI för Rebuttal: adaptive point mutation (Rosenberg and Hastings)

Experimental adaptation of Salmonella typhimurium to mice

Nilsson, Annika; Kugelberg, Elisabeth; Berg, Otto; Andersson, Dan I.

Ingår i Genetics, s. 1119-1130, 2004

• DOI för Experimental adaptation of Salmonella typhimurium to mice

Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Maisnier-Patin, Sophie; Andersson, Dan I

Ingår i Research in Microbiology, s. 360-369, 2004

• DOI för Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosis

Mariam, Deneke H; Mengistu, Yohannes; Hoffner, Sven E; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, s. 1289-1294, 2004

Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

Roth, John R; Andersson, Dan I

Ingår i Research in Microbiology, s. 342-351, 2004

• DOI för Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

Baquero, María-Rosario; Nilsson, Annika I; Turrientes, María del Carmen; Sandvang, Dorthe et al.

Ingår i Journal of Bacteriology, s. 5538-5542, 2004

• DOI för Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

The amplification model for adaptive mutation: simulations and analysis

Pettersson, M.; Andersson, Dan I; Roth, J R; Berg, O G

Ingår i Genetics, s. 1105-1115, 2004

• DOI för The amplification model for adaptive mutation: simulations and analysis

Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

Starck, Joakim; Källenius, Gunilla; Marklund, Britt-Inger; Andersson, Dan I et al.

Ingår i Microbiology, s. 3821-3829, 2004

• DOI för Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Gustafsson, Ingegerd; Sjölund, Maria; Torell, Erik; Johannesson, Marie et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 645-650, 2003

• DOI för Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori

Sjölund, Maria; Wreiber, Karin; Andersson, Dan I; Blaser, Martin J et al.

Ingår i Annals of Internal Medicine, s. 483-487, 2003

The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase

Lundin, Annelie; Nilsson, Christina; Gerhard, Markus; Andersson, Dan I et al.

Ingår i Journal of Biological Chemistry, s. 12574-12578, 2003

• DOI för The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase

Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori

Sjölund, Maria; Wreiber, Karin; Andersson, Dan I.; Blaser, Martin J. et al.

Ingår i Ann Intern Med, s. 483-7, 2003

Mutation frequency and biological cost of resistance in Helicobacter pylori.

Björkholm, Britta; Sjölund, Maria; Falk, Per G.; Berg, Otto G. et al.

Ingår i Proc Natl Acad Sci U S A, s. 14607-12, 2001

Muller's ratchet decreases fitness of a DNA-based microbe

Andersson, Dan I; Hughes, Diarmaid

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 906-907, 1996

Low conservation of antibiotic interactions between and within Gram-negative bacterial species

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikolaos et al.

Ingår i PLoS biology

The physiology and genetics of bacterial responses to antibiotic combinations

Roemhild, Roderich; Bollenbach, Tobias; Andersson, Dan I.

Ingår i Nature Reviews Microbiology, s. 478-490, 2022

• DOI för The physiology and genetics of bacterial responses to antibiotic combinations

Antibiotic resistance: turning evolutionary principles into clinical reality

Andersson, Dan I.; Balaban, Nathalie Q.; Baquero, Fernando; Courvalin, Patrice et al.

Ingår i FEMS Microbiology Reviews, s. 171-188, 2020

• DOI för Antibiotic resistance: turning evolutionary principles into clinical reality

Mechanisms and clinical relevance of bacterial heteroresistance

Andersson, Dan I; Nicoloff, Hervé; Hjort, Karin

Ingår i Nature Reviews Microbiology, s. 479-496, 2019

• DOI för Mechanisms and clinical relevance of bacterial heteroresistance

Definitions and guidelines for research on antibiotic persistence

Balaban, Nathalie Q.; Helaine, Sophie; Lewis, Kim; Ackermann, Martin et al.

Ingår i Nature Reviews Microbiology, s. 441-448, 2019

• DOI för Definitions and guidelines for research on antibiotic persistence
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Prediction of antibiotic resistance: time for a new preclinical paradigm?

Sommer, Morten O. A.; Munck, Christian; Toft-Kehler, Rasmus Vendler; Andersson, Dan I

Ingår i Nature Reviews Microbiology, s. 688-695, 2017

• DOI för Prediction of antibiotic resistance: time for a new preclinical paradigm?
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Evolutionary Trajectories to Antibiotic Resistance

Hughes, Diarmaid; Andersson, Dan I

Ingår i Annual Review of Microbiology, s. 579-596, 2017

• DOI för Evolutionary Trajectories to Antibiotic Resistance

Environmental and genetic modulation of the phenotypic expression of antibiotic resistance

Hughes, Diarmaid; Andersson, Dan I

Ingår i FEMS Microbiology Reviews, s. 374-391, 2017

• DOI för Environmental and genetic modulation of the phenotypic expression of antibiotic resistance

Mechanisms and consequences of bacterial resistance to antimicrobial peptides

Andersson, Dan I.; Hughes, Diarmaid; Kubicek-Sutherland, Jessica Z.

Ingår i Drug resistance updates, s. 43-57, 2016

• DOI för Mechanisms and consequences of bacterial resistance to antimicrobial peptides
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Evolution of New Functions De Novo and from Preexisting Genes

Andersson, Dan I.; Jerlström-Hultqvist, Jon; Näsvall, Joakim

Ingår i Cold Spring Harbor Perspectives in Biology, 2015

• DOI för Evolution of New Functions De Novo and from Preexisting Genes

Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms

Hughes, Diarmaid; Andersson, Dan I.

Ingår i Nature reviews genetics, s. 459-471, 2015

• DOI för Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms

Improving predictions of the risk of resistance development against new and old antibiotics

Andersson, Dan I.

Ingår i Clinical Microbiology and Infection, s. 894-898, 2015

• DOI för Improving predictions of the risk of resistance development against new and old antibiotics

Microbiological effects of sublethal levels of antibiotics

Andersson, Dan I.; Hughes, Diarmaid

Ingår i Nature Reviews Microbiology, s. 465-478, 2014

• DOI för Microbiological effects of sublethal levels of antibiotics

The origin of mutants under selection: Interactions of mutation, growth and selection

Andersson, Dan I.; Hughes, Diarmaid; Roth, John R

Ingår i EcoSal Plus, 2011

• DOI för The origin of mutants under selection: Interactions of mutation, growth and selection

Persistence of antibiotic resistance in bacterial populations

Andersson, Dan I.; Hughes, Diarmaid

Ingår i FEMS Microbiology Reviews, s. 901-911, 2011

• DOI för Persistence of antibiotic resistance in bacterial populations

Biological roles of translesion synthesis DNA polymerases in eubacteria

Andersson, Dan I.; Koskiniemi, Sanna; Hughes, Diarmaid

Ingår i Molecular Microbiology, s. 540-548, 2010

• DOI för Biological roles of translesion synthesis DNA polymerases in eubacteria

Antibiotic resistance and its cost: is it possible to reverse resistance?

Andersson, Dan I.; Hughes, Diarmaid

Ingår i Nature Reviews Microbiology, s. 260-271, 2010

• DOI för Antibiotic resistance and its cost: is it possible to reverse resistance?

Gene amplification and adaptive evolution in bacteria

Andersson, Dan I.; Hughes, Diarmaid

Ingår i Annual Review of Genetics, s. 167-195, 2009

• DOI för Gene amplification and adaptive evolution in bacteria

Bacterial gene amplification: implications for the evolution of antibiotic resistance

Sandegren, Linus; Andersson, Dan I.

Ingår i Nature Reviews Microbiology, s. 578-588, 2009

• DOI för Bacterial gene amplification: implications for the evolution of antibiotic resistance

Predicting antibiotic resistance

Martínez, José L.; Baquero, Fernando; Andersson, Dan I.

Ingår i Nature Reviews Microbiology, s. 958-965, 2007

• DOI för Predicting antibiotic resistance

Impact of the pan-genome of Escherichia coli on the potential for de novo antibiotic resistance evolution: Supplemental material: Figure S1

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S7

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S11 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S1

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S6

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the pan-genome of Escherichia coli on the potential for de novo antibiotic resistance evolution: Supplemental material: Table S1.

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S1 Data

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S2 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S10 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S8 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S4 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S2

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Adventures with mutation and selection in beehive and cow country

Hughes, Diarmaid; Andersson, Dan I

Ingår i The Lure of Bacterial Genetics, s. 245-253, ASM Press, 2010

Effects of antibiotic resistance on bacterial fitness, virulence and transmission

Andersson, Dan I.; Hughes, Diarmaid

Ingår i Evolutionary biology of bacterial and fungal pathogens, s. 307-318, ASM Press, 2008

The Biological Cost of Antibiotic resistance

Andersson, Dan I; Maisner Patin, Sophie; Nilsson, Annika; Kugelberg, Elisabeth

Ingår i Enzyme-Mediated Resistance to Antibiotics, s. 339-348, 2007

Investigation of linoleic acid as an antibacterial additive in bone cement

Hong, Linglu; Hjort, Karin; Andersson, Dan I.; Persson, Cecilia

2024

Antibiofilm Properties of Linoleic Acid-loaded Bone Cement with and without Gentamicin

Hong, Linglu; Hjort, Karin; Persson, Cecilia; Andersson, Dan I.

Ingår i 33rd Annual Conference of the European Society for Biomaterials, s. 46-46, 2023

An oxidative stress-induced bypass mechanism confers antibiotic resistance in Escherichia coli

Thulin, Elisabeth; Andersson, Dan I

Compensatory evolution in mecillinam resistant Escherichia coli

Thulin, Elisabeth; Knopp, Michael; Ekstrand, Emelie; Andersson, Dan I

Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on skin of human volunteers

Gustafsson, Ingegerd; Cars, Otto; Andersson, Dan I.

Fitness of Antibiotic-Resistant Staphylococcus epidermidis

Sjölund, Maria; Tano, Eva; Blaser, Martin J.; Andersson, Dan I. et al.

Extensive sharing and transmission of intestinal bacteria between couples before and after antibiotic treatment

Olofsson, Sara K.; Andersson, Dan I.; Cars, Otto

Initiation factor 2 mutants promoting fast joining of ribosomal subunits in the absence of initiator tRNA or GTP

Pavlov, Michael; Zorzet, Anna; Andersson, Dan I; Ehrenberg, Måns

Compensatory evolution restores fitness to actinonin-resistant Staphylococcus aureus

Zorzet, Anna; Nilsson, Annika; Andersson, Dan I

Fitness constraints on horizontal gene transfer

Lind, Peter A; Andersson, Dan I

Mutation in the Copper-Induced sil Operon Enables High-Level Silver Resistance and Silver Facilitated Co-Selection of Multidrug Resistance Plasmid

Albrecht, Lisa M; Sandegren, Linus; Andersson, Dan

Potentiation of the Selective Effect of Antibiotics by Metal Ions

Albrecht, Lisa M; Andersson, Dan I

Cross-Resistance to Antibiotics After Exposure to Qaternary Ammonium Compounds

Albrecht, Lisa M; Andersson, Dan I

Experimental evolution of novel metabolic capabilities in Salmonella enterica

Warsi, Omar M.; Lundin, Erik; Lustig, Ulrika; Näsvall, Joakim et al.

Functional trade-offs during evolution of new functions in the HisA-TrpF system

Lundin, Erik; Näsvall, Joakim; Andersson, Dan I

Spread of resistance plasmids and selection of resistant bacteria among Mallards exposed to sub-inhibitory concentrations of antibiotics in their water environment

Atterby, Clara; Nykvist, Marie; Lustig, Ulrika; Andersson, Dan I et al.

Structure of a phage-encoded SAMase enzyme provides insights in substrate binding and mechanism

Guo, Xiaohu; Söderholm, Annika; Kanchugal Puttaswamy, Sandesh; Isaksen, Geir et al.

The pan-genome of Escherichia coli strongly affects the potential for de novo antibiotic resistance evolution

Jagdmann, Jennifer; Guliaev, Andrei; Andersson, Dan I.; Nicoloff, Hervé

Impact of the bacterial genetic background on plasmid-borne antibiotic resistance

Jagdmann, Jennifer; Saubi Puignau, Cristina; Andersson, Dan I.; Nicoloff, Hervé

Host-specific determinants of Legionella pneumophila virulence passaged in single hosts and in alternation

Moreno, Anaísa B.; Paranjape, Kiran; Kay, Elisabeth; Dobre Lereanu, Christian et al.

Mutations that alter the synergistic interaction of tetracycline and spectinomycin in Escherichia coli

Tang, Po-Cheng; Valdaliso, Eunate; Westhoff, Sanne; Sánchez-Hevia, Dione L. et al.

Structure of a phage-encoded SAM hydrolase enzyme provides insights in substrate binding and catalysis

Söderholm, Annika; Selmer, Maria; Guo, Xiaohu; Kanchugal Puttaswamy, Sandesh et al.

Ribosomal protein L1 is required for balanced formation of ribosomal subunits

Tobin, Christina; Nord, Stefan; Wikström, P. Mikael; Näsvall, Joakim et al.

The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing: Appendix files

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

2025

Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Ingår i Lancet Microbe, 2025

• DOI för Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
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