Mats Gustafsson

Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma

Chantzi, Efthymia; Hammerling, Ulf; Gustafsson, Mats G.

Ingår i Computers in Biology and Medicine, 2024

• DOI för Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
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COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics

Chantzi, Efthymia; Neidlin, Michael; Macheras, George A.; Alexopoulos, Leonidas G. et al.

Ingår i PLOS ONE, 2020

• DOI för COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
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A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

Neidlin, Michael; Chantzi, Efthymia; Macheras, George; Gustafsson, Mats G et al.

Ingår i Annals of Biomedical Engineering, s. 2438-2448, 2020

• DOI för A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Ingår i BMC Bioinformatics, 2019

• DOI för COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns

Neidlin, Michael; Chantzi, Efthymia; Macheras, George; Gustafsson, Mats G. et al.

Ingår i PLOS ONE, 2019

• DOI för An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
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Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma

Chantzi, Efthymia; Hammerling, Ulf; Gustafsson, Mats G.

Ingår i Computers in Biology and Medicine, 2024

• DOI för Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma
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COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics

Chantzi, Efthymia; Neidlin, Michael; Macheras, George A.; Alexopoulos, Leonidas G. et al.

Ingår i PLOS ONE, 2020

• DOI för COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
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A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

Neidlin, Michael; Chantzi, Efthymia; Macheras, George; Gustafsson, Mats G et al.

Ingår i Annals of Biomedical Engineering, s. 2438-2448, 2020

• DOI för A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Ingår i BMC Bioinformatics, 2019

• DOI för COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns

Neidlin, Michael; Chantzi, Efthymia; Macheras, George; Gustafsson, Mats G. et al.

Ingår i PLOS ONE, 2019

• DOI för An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
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Investigations Of Cytokine Interplay With An In Vitro Model Of Osteoarthritis

Neidlin, M.; Chantzi, Efthymia; Macheras, G.; Gustafsson, Mats G et al.

Ingår i Osteoarthritis and Cartilage, 2018

COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Ingår i BMC Bioinformatics, 2018

• DOI för COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
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Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R

Bäcklin, Christofer L.; Gustafsson, Mats G.

Ingår i Journal of Statistical Software, s. 1-30, 2018

• DOI för Developer-Friendly and Computationally Efficient Predictive Modeling without Information Leakage: The emil Package for R
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Self-tuning density estimation based on Bayesian averaging of adaptive kernel density estimations yields state-of-the-art performance

Bäcklin, Christofer; Andersson, Claes; Gustafsson, Mats G

Ingår i Pattern Recognition, s. 133-143, 2018

• DOI för Self-tuning density estimation based on Bayesian averaging of adaptive kernel density estimations yields state-of-the-art performance

Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.

Eriksson, Anna; Chantzi, Efthymia; Fryknäs, Mårten; Gullbo, Joachim et al.

Ingår i Leukemia Research, s. 41-46, 2017

• DOI för Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
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Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism

Kashif, Muhammad; Andersson, Claes; Mansoori, Sharmineh; Larsson, Rolf et al.

Ingår i Oncotarget, s. 103952-103967, 2017

• DOI för Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism
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Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.

Herman, Stephanie; Emami Khoonsari, Payam; Aftab, Obaid; Krishnan, Shibu et al.

Ingår i Metabolomics, 2017

• DOI för Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.
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Targeting tumor cells based on Phosphodiesterase 3A expression

Nazir, Madiha; Senkowski, Wojciech; Nyberg, Frida; Blom, Kristin et al.

Ingår i Experimental Cell Research, s. 308-315, 2017

• DOI för Targeting tumor cells based on Phosphodiesterase 3A expression

Characterizing the effects of epigenetic regulation in assays using peripheral blood mononuclear cells from patients with inflammatory diseases

Berg, L.; Sundström, Y.; Aftab, Obaid; Bergqvist, F. et al.

Ingår i Scandinavian Journal of Rheumatology, s. 44-45, 2016

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergström, Tobias et al.

Ingår i Cell Reports, s. 2994-3009, 2016

• DOI för Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
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A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Ingår i PLOS ONE, 2016

• DOI för A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
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Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids

Senkowski, Wojciech; Jarvius, Malin; Rubin, Jenny; Lengqvist, Johan et al.

Ingår i CELL CHEMICAL BIOLOGY, s. 1428-1438, 2016

• DOI för Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids

Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia

Österroos, Albin; Kashif, Muhammad; Haglund, Caroline; Blom, Kristin et al.

Ingår i Biochemical Pharmacology, s. 40-49, 2016

• DOI för Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia

Repositioning Of Quinacrine For Treatment Of Acute Myeloid Leukemia - Synergies And In Vivo Effects

Eriksson, Anna; Gustafsson, Mats; Fryknäs, Mårten; Gullbo, Joachim et al.

Ingår i Haematologica, s. 367-368, 2016

Label free quantification of time evolving morphologies using time-lapse video microscopy enables identity control of cell lines and discovery of chemically induced differential activity in iso-genic cell line pairs

Aftab, Obaid; Fryknäs, Mårten; Hassan, Saadia; Nygren, Peter et al.

Ingår i Chemometrics and Intelligent Laboratory Systems, s. 24-32, 2015

• DOI för Label free quantification of time evolving morphologies using time-lapse video microscopy enables identity control of cell lines and discovery of chemically induced differential activity in iso-genic cell line pairs

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

Senkowski, Wojciech; Zhang, Xiaonan; Olofsson, Maria Hagg; Isacson, Ruben et al.

Ingår i Molecular Cancer Therapeutics, s. 1504-1516, 2015

• DOI för Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

Spheroid-based high throughput screening for identification of molecules targeting different tumor microenvironment characteristics

Senkowski, Wojciech; Zhang, Xiaonan; Nygren, Peter; Olofsson, Maria Hagg et al.

Ingår i Cancer Research, 2015

• DOI för Spheroid-based high throughput screening for identification of molecules targeting different tumor microenvironment characteristics

In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index

Kashif, Muhammad; Andersson, Claes; Hassan, Sadia; Karlsson, Henning et al.

Ingår i Scientific Reports, 2015

• DOI för In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index
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A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets

Freyhult, Eva; Gustafsson, Mats G.; Strömbergsson, Helena

Ingår i Molecular Informatics, s. 44-52, 2015

• DOI för A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Ingår i Clinical Epigenetics, 2015

• DOI för DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
• Ladda ner fulltext (pdf) av DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Detection of cell aggregation and altered cell viability by automated label-free video microscopy: A promising alternative to endpoint viability assays in high throughput screening

Aftab, Obaid; Fryknäs, Mårten; Hammerling, Ulf; Larsson, Rolf et al.

Ingår i Journal of Biomolecular Screening, s. 372-381, 2015

• DOI för Detection of cell aggregation and altered cell viability by automated label-free video microscopy: A promising alternative to endpoint viability assays in high throughput screening

Translational Research in Complementary and Alternative Medicine 2014

Jia, Wei; Lu, Aiping; Chan, Kelvin; Gustafsson, Mats G. et al.

Ingår i Evidence-based Complementary and Alternative Medicine, 2015

• DOI för Translational Research in Complementary and Alternative Medicine 2014
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Identifying Food Consumption Patterns among Young Consumers by Unsupervised and Supervised Multivariate Data Analysis

Hammerling, Ulf; Freyhult, Eva; Edberg, Anna; Sand, Salomon et al.

Ingår i European Journal of Nutrition & Food Safety, s. 392-403, 2014

• DOI för Identifying Food Consumption Patterns among Young Consumers by Unsupervised and Supervised Multivariate Data Analysis

Label-free detection and dynamic monitoring of drug-induced intracellular vesicle formation enabled using a 2-dimensional matched filter

Aftab, Obaid; Fryknäs, Mårten; Zhang, Xiaonan; De Milito, Angelo et al.

Ingår i Autophagy, s. 57-69, 2014

• DOI för Label-free detection and dynamic monitoring of drug-induced intracellular vesicle formation enabled using a 2-dimensional matched filter

Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing

Aftab, Obaid; Nazir, Madiha; Fryknäs, Mårten; Hammerling, Ulf et al.

Ingår i Apoptosis (London), s. 1411-1418, 2014

• DOI för Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing

A Pragmatic Definition of Therapeutic Synergy Suitable for Clinically Relevant In Vitro Multicompound Analyses

Kashif, Muhammad; Andersson, Claes; Åberg, Magnus; Nygren, Peter et al.

Ingår i Molecular Cancer Therapeutics, s. 1964-1976, 2014

• DOI för A Pragmatic Definition of Therapeutic Synergy Suitable for Clinically Relevant In Vitro Multicompound Analyses

NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

Aftab, Obaid; Engskog, Mikael; Haglöf, Jakob; Elmsjö, Albert et al.

Ingår i Journal of chemical information and modeling, s. 3251-3258, 2014

• DOI för NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Ingår i Genome Biology, 2013

• DOI för Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Automated QuantMap for rapid quantitative molecular network topology analysis

Schaal, Wesley; Hammerling, Ulf; Gustafsson, Mats G; Spjuth, Ola

Ingår i Bioinformatics, s. 2369-2370, 2013

• DOI för Automated QuantMap for rapid quantitative molecular network topology analysis
• Ladda ner fulltext (pdf) av Automated QuantMap for rapid quantitative molecular network topology analysis

Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

Fryknäs, Mårten; Gullbo, Joachim; Wang, Xin; Rickardson, Linda et al.

Ingår i BMC Cancer, s. 374, 2013

• DOI för Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
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A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

Enroth, Stefan; Andersson, Claes R.; Andersson, Robin; Wadelius, Claes et al.

Ingår i Algorithms for Molecular Biology, s. 2, 2012

• DOI för A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements
• Ladda ner fulltext (pdf) av A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Nordlund, Jessica; Kiialainen, Anna; Karlberg, Olof; Berglund, Eva C et al.

Ingår i Leukemia, s. 1218-1227, 2012

• DOI för Digital gene expression profiling of primary acute lymphoblastic leukemia cells

The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Nordlund, Jessica; Backlin, Carin; Wahlberg, Per; Forestier, E. et al.

Ingår i European Journal of Cancer, 2012

• DOI för The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Analysis of intraosseous samples using point of care technology: an experimental study in the anaesthetised pig

Strandberg, Gunnar; Eriksson, Mats; Gustafsson, Mats G; Lipcsey, Miklós et al.

Ingår i Resuscitation, s. 1381-1385, 2012

• DOI för Analysis of intraosseous samples using point of care technology: an experimental study in the anaesthetised pig

Assessing Relative Bioactivity of Chemical Substances Using Quantitative Molecular Network Topology Analysis

Edberg, Anna; Soeria-Atmadja, Daniel; Laurila, Jonas Bergman; Johansson, Fredrik et al.

Ingår i Journal of Chemical Information and Modeling, s. 1238-1249, 2012

• DOI för Assessing Relative Bioactivity of Chemical Substances Using Quantitative Molecular Network Topology Analysis

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Darmanis, Spyros; Nong, Rachel Yuan; Vänelid, Johan; Siegbahn, Agneta et al.

Ingår i PLOS ONE, 2011

• DOI för ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Abundance and functional roles of intrinsic disorder in allergenic proteins and allergen representative peptides

Xue, Bin; Soeria-Atmadja, Daniel; Gustafsson, Mats G.; Hammerling, Ulf et al.

Ingår i Proteins, s. 2595-2606, 2011

• DOI för Abundance and functional roles of intrinsic disorder in allergenic proteins and allergen representative peptides

Interrogating health-related public databases from a food toxicology perspective: Computational analysis of scoring data

Maddah, Farzaneh; Soeria-Atmadja, Daniel; Malm, Patrik; Gustafsson, Mats G. et al.

Ingår i Food and Chemical Toxicology, s. 2830-2840, 2011

• DOI för Interrogating health-related public databases from a food toxicology perspective: Computational analysis of scoring data

Multiplexed Homogeneous Proximity Ligation Assays for High-throughput Protein Biomarker Research in Serological Material

Lundberg, Martin; Thorsen, Stine Buch; Assarsson, Erika; Villablanca, Andrea et al.

Ingår i Molecular & Cellular Proteomics, 2011

• DOI för Multiplexed Homogeneous Proximity Ligation Assays for High-throughput Protein Biomarker Research in Serological Material

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Milani, Lili; Lundmark, Anders; Kiialainen, Anna; Nordlund, Jessica et al.

Ingår i Blood, s. 1214-1225, 2010

• DOI för DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Improving Bayesian credibility intervals for classifier error rates using maximum entropy empirical priors

Gustafsson, Mats G.; Wallman, Mikael; Wickenberg-Bolin, Ulrika; Göransson, Hanna et al.

Ingår i Artificial Intelligence in Medicine, s. 93-104, 2010

• DOI för Improving Bayesian credibility intervals for classifier error rates using maximum entropy empirical priors

In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukaemia: rolipram and prednisolone active in cells from patients with poor prognosis

Lindhagen, Elin; Norberg, Maria; Kanduri, Meena; Tobin, Gerard et al.

Ingår i European Journal of Haematology, s. 22-34, 2009

• DOI för In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukaemia: rolipram and prednisolone active in cells from patients with poor prognosis

Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination

Åleskog, Anna; Norberg, Maria; Nygren, Peter; Rickardson, Linda et al.

Ingår i Leukemia and Lymphoma, s. 2333-2343, 2008

• DOI för Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination

Cross-validation and bootstrapping are unreliable in small sample classification

Isaksson, Anders; Wallman, M.; Göransson, Hanna; Gustafsson, Mats.G.

Ingår i Pattern Recognition Letters, s. 1960-1965, 2008

• DOI för Cross-validation and bootstrapping are unreliable in small sample classification

Revealing cell cycle control by combining model-based detection of periodic expression with novel cis-regulatory descriptors

Andersson, Claes R.; Hvidsten, Torgeir R.; Isaksson, Anders; Gustafsson, Mats G. et al.

Ingår i BMC Systems Biology, s. 45, 2007

• DOI för Revealing cell cycle control by combining model-based detection of periodic expression with novel cis-regulatory descriptors

EVALLER: a web server for in silico assessment of potential protein allergenicity

Martinez Barrio, Alvaro; Soeria-Atmadja, Daniel; Nistér, Anders; Gustafsson, Mats G. et al.

Ingår i Nucleic Acids Research, 2007

• DOI för EVALLER: a web server for in silico assessment of potential protein allergenicity

Effective brain connectivity in social anxiety disorder: a Bayesian approach

Ågren, Thomas; Bjurström, Anders; Åhs, Fredrik; Furmark, Tomas et al.

Ingår i Biological Psychiatry, 2007

STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines

Fryknäs, Mårten; Dhar, Sumeer; Öberg, Fredrik; Rickardson, Linda et al.

Ingår i International Journal of Cancer, s. 189-195, 2007

• DOI för STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines

Multivariate statistical analysis of large-scale IgE antibody measurements reveals allergen extract relationships in sensitized individuals

Soeria-Atmadja, Daniel; Önell, Annica; Kober, Anita; Mattson, Per et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 1433-1440, 2007

• DOI för Multivariate statistical analysis of large-scale IgE antibody measurements reveals allergen extract relationships in sensitized individuals

In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency

Andersson, Claes R.; Fryknäs, Mårten; Rickardson, Linda; Larsson, Rolf et al.

Ingår i Journal of chemical information and modeling, s. 239-248, 2007

• DOI för In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency

Improved variance estimation of classification performance via reduction of bias caused by small sample size

Wickenberg Bolin, Ulrika; Göransson, Hanna; Fryknäs, Mårten; Gustafsson, Mats G et al.

Ingår i BMC Bioinformatics, s. 127, 2006

Screening of an annotated compound library for drug activity in a resistant myeloma cell line

Rickardson, Linda; Fryknäs, Mårten; Haglund, Caroline; Lövborg, Henrik et al.

Ingår i Cancer Chemotherapy and Pharmacology, s. 749-758, 2006

• DOI för Screening of an annotated compound library for drug activity in a resistant myeloma cell line

Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model

Fryknäs, Mårten; Rickardson, Linda; Wickström, Malin; Dhar, Sumeer et al.

Ingår i Journal of Biomolecular Screening, s. 457-468, 2006

• DOI för Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model

Molecular markers for discrimination of benign and malignant follicular thyroid tumors

Fryknäs, Mårten; Wickenberg Bolin, Ulrika; Göransson, Hanna; Gustafsson, Mats G et al.

Ingår i Tumor Biology, s. 211-220, 2006

• DOI för Molecular markers for discrimination of benign and malignant follicular thyroid tumors

Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling

Freyhult, Eva; Prusis, Peteris; Lapinsh, Maris; Wikberg, Jarl E S et al.

Ingår i BMC Bioinformatics, s. 50, 2005

• DOI för Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling

External cross-validation for unbiased evaluation of protein family detectors: application to allergens

Soeria-Atmadja, Daniel; Wallman, Mikael; Björklund, Åsa K.; Isaksson, Anders et al.

Ingår i Proteins, s. 918-925, 2005

• DOI för External cross-validation for unbiased evaluation of protein family detectors: application to allergens

Supervised identification of allergen-representative peptides yields improved in silico detection of allergenic proteins

Björklund, A K; Soeria-Admadja, D; Hammerling, U; Gustafsson, Mats G

Ingår i Bioinformatics, s. 39-50, 2005

Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles

Rickardson, Linda; Fryknäs, Mårten; Dhar, Sumeer; Lövborg, Henrik et al.

Ingår i British Journal of Cancer, s. 483-492, 2005

Independent component analysis yields chemically interpretable latent variables in multivariate regression

Gustafsson, Mats G

Ingår i Journal of Chemical Information and Modeling, s. 1244-1255, 2005

Structural modeling extends QSAR analysis of antibody-lysozyme interactions to 3D-QSAR

Freyhult, E; Andersson, K; Gustafsson, M G

Ingår i Biophysical Journal, s. 2264-2272, 2003

Prediction of food protein allergenicity: A bioinformatic learning systems approach

Zorzet, A; Gustafsson, Mats; Hammerling, U

Ingår i Silico Biol 2, s. 525-534, 2002

Exhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma using COMBImageDL

Chantzi, Efthymia; Hammerling, Ulf; Gustafsson, Mats G

Ingår i Molecular Cancer Therapeutics

Quantitative Chemogenomics: Machine-Learning Models of Protein-Ligand Interaction

Andersson, Claes R.; Gustafsson, Mats G.; Strömbergsson, Helena

Ingår i Current Topics in Medicinal Chemistry, s. 1978-1993, 2011

• DOI för Quantitative Chemogenomics: Machine-Learning Models of Protein-Ligand Interaction

Effective Connectivity of Fear Circuitry and Emotion Regulation in Specific Phobia

Ågren, Thomas; Faria, Vanda; Engman, Jonas; Furmark, Tomas et al.

2011

Drug combination screening in multicellular tumor spheroids identifies synthetic lethalities in quiescent cancer cells

Senkowski, Wojciech; Nazir, Madiha; Gustafsson, Mats G; Nygren, Peter et al.