Daniel Molin – Clinical and translational research in lymphoma, especially Hodgkin lymphoma
Our research focuses primarily on lymphoma, particularly Hodgkin lymphoma. The overall aim of our work is to improve both outcomes and quality of life for patients.
We study treatment effects and adverse events in routine clinical practice (epidemiology) and work to identify early prognostic markers for both treatment outcomes and toxicity using genetic analyses, proteomics, and PET/CT.
We also evaluate new treatment approaches, such as proton therapy, within the framework of our investigator-initiated clinical trial PRO-Hodgkin. In addition, we participate in studies of other methods aimed at reducing late adverse effects following lymphoma treatment, for example a study on physical exercise (LYMfit).
Using proteomics and various methods to characterise the tumour microenvironment, we also investigate the biology of Hodgkin lymphoma, in particular its relationship with inflammation.
Finally, my research group and I are actively engaged in international clinical trials in lymphoma, with the aim of contributing to future treatment strategies.
Group members
Publications
Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma.
Part of Cardio-oncology, 2026
- DOI for Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma.
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Part of Physica medica (Testo stampato), 2026
- DOI for Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
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Part of Haematologica, p. 2356-2366, 2025
- DOI for A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma
- Download full text (pdf) of A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma
Part of Blood Cancer Journal, 2025
- DOI for Advanced stage classical Hodgkin lymphoma patients with a positive interim-PET (PET-2) Deauville score 5 after 2 ABVD cycles: a pooled analysis of three multicenter trials
- Download full text (pdf) of Advanced stage classical Hodgkin lymphoma patients with a positive interim-PET (PET-2) Deauville score 5 after 2 ABVD cycles: a pooled analysis of three multicenter trials
Part of HemaSphere, 2025
Part of HemaSphere, 2025
- DOI for Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
- Download full text (pdf) of Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
Part of The Lancet Oncology, p. 1081-1090, 2025
- DOI for Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial
- Download full text (pdf) of Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial
Part of Acta Oncologica, p. 1540-1543, 2025
- DOI for Improved therapies, incomplete data: late toxicity after modern classical Hodgkin Lymphoma radiotherapy
- Download full text (pdf) of Improved therapies, incomplete data: late toxicity after modern classical Hodgkin Lymphoma radiotherapy
Part of Physica medica (Testo stampato), 2025
- DOI for Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
- Download full text (pdf) of Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
Part of Haematologica, p. 2866-2867, 2025
- DOI for Response to Comment on: "A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma"
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Aging Kairos: treating older Hodgkin patients
Part of Blood, p. 943-945, 2024
Part of The Lancet, p. 341-352, 2024
- DOI for Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial
- Download full text (pdf) of Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial
Part of eJHaem, p. 1190-1200, 2024
- DOI for Congestive heart failure after anthracycline-containing treatment for Hodgkin lymphoma: A Swedish matched cohort study
- Download full text (pdf) of Congestive heart failure after anthracycline-containing treatment for Hodgkin lymphoma: A Swedish matched cohort study
Diagnostik och behandling av klassiskt Hodgkins lymfom
Part of Läkartidningen, 2024
Part of British Journal of Haematology, p. 1794-1803, 2024
- DOI for Evaluation of coverage, generalisability and validity of the U-CAN lymphoma biobank in Sweden: A comparison with nationwide registers
- Download full text (pdf) of Evaluation of coverage, generalisability and validity of the U-CAN lymphoma biobank in Sweden: A comparison with nationwide registers
Part of Acta Oncologica, p. 164-168, 2024
- DOI for Impact of the COVID-19 pandemic on lymphoma incidence and short-term survival - a Swedish Lymphoma Register Study
- Download full text (pdf) of Impact of the COVID-19 pandemic on lymphoma incidence and short-term survival - a Swedish Lymphoma Register Study
Part of Heliyon, 2024
- DOI for Improved automated tumor segmentation in whole-body 3D scans using multi-directional 2D projection-based priors
- Download full text (pdf) of Improved automated tumor segmentation in whole-body 3D scans using multi-directional 2D projection-based priors
Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
Part of Journal of Clinical Oncology, p. 13-18, 2024
- DOI for Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
- Download full text (pdf) of Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
The National Swedish Lymphoma Register - a systematic validation of data quality
Part of Acta Oncologica, p. 563-572, 2024
- DOI for The National Swedish Lymphoma Register - a systematic validation of data quality
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Part of Blood, p. 878-886, 2023
NLPHL: a hummingbird in an owl's nest
Part of Blood, p. 499-500, 2023
Part of International Journal of Cancer, p. 723-731, 2023
- DOI for Reproduction patterns among classical Hodgkin lymphoma survivors treated with BEACOPP and ABVD in Sweden, Denmark and Norway-A population-based matched cohort study
- Download full text (pdf) of Reproduction patterns among classical Hodgkin lymphoma survivors treated with BEACOPP and ABVD in Sweden, Denmark and Norway-A population-based matched cohort study
Part of Blood Advances, p. 5304-5313, 2023
An image registration method for voxel-wise analysis of whole-body oncological PET-CT
Part of Scientific Reports, 2022
- DOI for An image registration method for voxel-wise analysis of whole-body oncological PET-CT
- Download full text (pdf) of An image registration method for voxel-wise analysis of whole-body oncological PET-CT
Checkpoint CD47 expression in classical Hodgkin lymphoma
Part of British Journal of Haematology, p. 580-589, 2022
- DOI for Checkpoint CD47 expression in classical Hodgkin lymphoma
- Download full text (pdf) of Checkpoint CD47 expression in classical Hodgkin lymphoma
Part of Cancers, 2022
- DOI for Expression of PD-1, PD-L1 and PD-L2 in Lymphomas in Patients with Pre-Existing Rheumatic Diseases-A Possible Association with High Rheumatoid Arthritis Disease Activity
- Download full text (pdf) of Expression of PD-1, PD-L1 and PD-L2 in Lymphomas in Patients with Pre-Existing Rheumatic Diseases-A Possible Association with High Rheumatoid Arthritis Disease Activity
Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
Part of Cancers, 2022
- DOI for Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
- Download full text (pdf) of Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
Part of Journal of Clinical Oncology, p. 1487-1496, 2022
- DOI for Limited, But Not Eliminated, Excess Long-Term Morbidity in Stage I-IIA Hodgkin Lymphoma Treated With Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine and Limited-Field Radiotherapy
- Download full text (pdf) of Limited, But Not Eliminated, Excess Long-Term Morbidity in Stage I-IIA Hodgkin Lymphoma Treated With Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine and Limited-Field Radiotherapy
Part of New Biotechnology, p. 21-29, 2022
- DOI for Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls
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Part of Upsala Journal of Medical Sciences, 2021
- DOI for High risk of cardiovascular side effects after treatment of Hodgkin's lymphoma - is there a need for intervention in long-term survivors?
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Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
Part of Cardio-Oncology, 2021
- DOI for Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
- Download full text (pdf) of Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
Part of Acta Oncologica, p. 771-778, 2021
- DOI for Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
- Download full text (pdf) of Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
Part of Haematologica, p. 2502-2506, 2021
- DOI for Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
- Download full text (pdf) of Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
Part of eJHaem, p. 400-412, 2021
- DOI for Real-world data on treatment concepts in classical Hodgkin lymphoma in Sweden 2000-2014, focusing on patients aged >60 years
- Download full text (pdf) of Real-world data on treatment concepts in classical Hodgkin lymphoma in Sweden 2000-2014, focusing on patients aged >60 years
Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma
Part of Blood Advances, p. 1671-1681, 2021
Part of Upsala Journal of Medical Sciences, 2021
- DOI for Serum concentrations of Thymidine kinase 1 measured using a novel antibody-based assay in patients with Hodgkin Lymphoma
- Download full text (pdf) of Serum concentrations of Thymidine kinase 1 measured using a novel antibody-based assay in patients with Hodgkin Lymphoma
CD30 expression and survival in posttransplant lymphoproliferative disorders
Part of Acta Oncologica, p. 673-680, 2020
- DOI for CD30 expression and survival in posttransplant lymphoproliferative disorders
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Part of British Journal of Haematology, p. 661-671, 2020
Part of British Journal of Haematology, p. 685-691, 2020
Pembrolizumab in relapsed or refractory Richter syndrome
Part of British Journal of Haematology, 2020
- DOI for Pembrolizumab in relapsed or refractory Richter syndrome
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Part of Leukemia and Lymphoma, p. 950-954, 2020
Part of Immunobiology, 2020
- DOI for Precursor cells and implications of a T-cell inflamed immune response in the pre-malignant setting in Hodgkin lymphoma
- Download full text (pdf) of Precursor cells and implications of a T-cell inflamed immune response in the pre-malignant setting in Hodgkin lymphoma
Part of Leukemia and Lymphoma, p. 376-384, 2019
- DOI for Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation
- Download full text (pdf) of Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation
Part of British Journal of Haematology, p. 431-439, 2019
Part of British Journal of Haematology, p. 192-201, 2019
Part of Upsala Journal of Medical Sciences, p. 105-110, 2019
- DOI for Intratumoral expression of FoxP3-positive regulatory T-cells in T-cell lymphoma: no correlation with survival
- Download full text (pdf) of Intratumoral expression of FoxP3-positive regulatory T-cells in T-cell lymphoma: no correlation with survival
Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087
Part of Blood, p. 1144-1153, 2019
Part of European Journal of Haematology, p. 88-97, 2018
- DOI for An anergic immune signature in the tumor microenvironment of classical Hodgkin lymphoma is associated with inferior outcome
- Download full text (pdf) of An anergic immune signature in the tumor microenvironment of classical Hodgkin lymphoma is associated with inferior outcome
Part of Annals of Hematology, p. 2129-2135, 2018
- DOI for Does the omission of vincristine in patients with diffuse large B cell lymphoma affect treatment outcome?
- Download full text (pdf) of Does the omission of vincristine in patients with diffuse large B cell lymphoma affect treatment outcome?
Part of PLOS ONE, 2018
- DOI for Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma
- Download full text (pdf) of Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma
Part of Acta Oncologica, p. 276-282, 2018
- DOI for Hodgkin lymphoma in children, adolescents and young adults - a comparative study of clinical presentation and treatment outcome.
- Download full text (pdf) of Hodgkin lymphoma in children, adolescents and young adults - a comparative study of clinical presentation and treatment outcome.
Part of Blood Advances, p. 1427-1439, 2017
Part of British Journal of Haematology, p. 449-456, 2017
Part of Journal of Clinical Oncology, p. 2125-2132, 2017
Part of Haematologica, p. 1-2, 2016
Part of Haematologica, p. 36-36, 2016
Part of Haematologica, p. 22-22, 2016
Part of British Journal of Haematology, p. 236-244, 2016
Part of Blood, p. 1531-1538, 2016
Part of Haematologica, p. 3-3, 2016
Part of Haematologica, p. 42-42, 2016
Part of European Journal of Haematology, p. 430-438, 2016
- DOI for The role of tumour-infiltrating eosinophils, mast cells and macrophages in Classical and Nodular Lymphocyte Predominant Hodgkin Lymphoma in children
- Download full text (pdf) of The role of tumour-infiltrating eosinophils, mast cells and macrophages in Classical and Nodular Lymphocyte Predominant Hodgkin Lymphoma in children
Part of Transplantation, p. 1036-1042, 2015
Part of Clinical Radiology, p. 1229-1236, 2015
Part of Acta Oncologica, p. 669-679, 2014
Part of Blood, 2014
Part of Acta Oncologica, p. 1271-1275, 2014
Part of Histopathology, p. 26-32, 2012
Long term risk of infections in Hodgkin lymphoma long-term survivors
Part of British Journal of Haematology, p. 661-663, 2011
Pediatric Organ Transplantation and Risk of Premalignant and Malignant Tumors in Sweden
Part of American Journal of Transplantation, p. 146-151, 2011
Part of European Journal of Haematology, p. 208-216, 2011
The effect of Eosinophil cationic protein (ECP) on Hodgkin lymphoma cell lines
Part of Experimental Hematology, p. 850-858, 2011
Whole-body diffusion-weighted imaging compared with FDG-PET/CT in staging of lymphoma patients
Part of Acta Radiologica, p. 173-180, 2011
Part of Nature Genetics, p. 1126-1130, 2010
Part of Acta Oncologica, p. 526-528, 2010
Framgångens baksida: Sena biverkningar av strålbehandling vid Hodgkins lymfom
Part of Läkartidningen, p. 2731-2732, 2010
Framgångens baksida: Sena biverkningar av strålbehandling vid Hodgkins lymfom
Part of Läkartidningen, p. 2731-2732, 2010
Mast cells in squamous cell esophageal carcinoma and clinical parameters
Part of Cancer Genomics & Proteomics, p. 25-29, 2010
Serum YKL-40 and interleukin 6 levels in Hodgkin lymphoma
Part of Clinical Cancer Research, p. 6974-8, 2008
Cigarette smoking and risk of Hodgkin lymphoma: a population-based case-control study
Part of Cancer Epidemiology, Biomarkers and Prevention, p. 1561-1566, 2007
Infectious mononucleosis, childhood social environment, and risk of Hodgkin lymphoma
Part of Cancer Research, p. 2382-2388, 2007
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma
Part of British Journal of Haematology, p. 68-71, 2007
The potential role of innate immunity in the pathogenesis of Hodgkin's lymphoma
Part of Hematology/Oncology Clinics of North America, p. 805-823, 2007
IL-9 expression contributes to the cellular composition in Hodgkin lymphoma
Part of European Journal of Haematology, p. 278-283, 2006
Angiogenesis and mast cells in Hodgkin lymphoma
Part of Leukemia, p. 2360-2362, 2005
Part of Scand J Infect Dis, p. 902-4, 2005
Bystander cells and prognosis in Hodgkin lymphoma. Review based on a doctoral thesis.
Part of Ups J Med Sci, p. 179-228, 2004
Part of Leukemia, p. 2513, 2003
Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma
Part of British Journal of Haematology, p. 122-124, 2002