Daniel Molin – Klinisk och translationell forskning inom lymfom, speciellt Hodgkins lymfom
Vår forskning fokuserar främst på lymfom, särskilt Hodgkins lymfom. Det övergripande målet är att förbättra både behandlingsresultat och livskvalitet för patienterna.
Vi studerar behandlingseffekter och biverkningar i klinisk rutin (epidemiologi) och arbetar för att identifiera tidiga prognostiska markörer för både behandlingsresultat och biverkningar med hjälp av genetiska analyser, proteomik och PET/CT.
Vi utvärderar också nya behandlingsmetoder, såsom protonterapi, inom ramen för den egna behandlingsstudien PRO-Hodgkin. Därutöver deltar vi i studier av andra metoder att minska sena biverkningar efter lymfombehandling. Exempelvis deltar vi i en studie om fysisk träning (LYMfit).
Med hjälp av proteomik och olika metoder för att kartlägga mikromiljön i tumörerna studerar vi också biologin hos Hodgkins lymfom, i synnerhet kopplingen till inflammation.
Slutligen är jag och min forskargrupp aktivt engagerade i internationella kliniska behandlingsstudier inom lymfom, med målet att bidra till framtida behandlingsstrategier.
Gruppmedlemmar
Publikationer
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Ingår i Physica medica (Testo stampato), 2026
- DOI för Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
- Ladda ner fulltext (pdf) av Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
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Ingår i Blood Advances, s. 4889-4897, 2026
- DOI för AVD is an effective chemotherapy backbone in first-line treatment of older patients with classical Hodgkin lymphoma
- Ladda ner fulltext (pdf) av AVD is an effective chemotherapy backbone in first-line treatment of older patients with classical Hodgkin lymphoma
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Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma
Ingår i Cardio-Oncology, 2026
- DOI för Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma
- Ladda ner fulltext (pdf) av Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma
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Glowing evidence: radiation shines in early NLPHL
Ingår i Blood Advances, s. 5411-5412, 2026
- DOI för Glowing evidence: radiation shines in early NLPHL
- Ladda ner fulltext (pdf) av Glowing evidence: radiation shines in early NLPHL
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Mortality in Patients With Hodgkin Lymphoma and Heart Failure: A Swedish Population-Based Study
Ingår i JACC: Advances, 2026
- DOI för Mortality in Patients With Hodgkin Lymphoma and Heart Failure: A Swedish Population-Based Study
- Ladda ner fulltext (pdf) av Mortality in Patients With Hodgkin Lymphoma and Heart Failure: A Swedish Population-Based Study
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Ingår i Leukemia and Lymphoma, s. 1327-1334, 2026
- DOI för Neoehrlichia mikurensis infection associated with lymphoma or mimicking lymphoma in two cohorts of Swedish patients
- Ladda ner fulltext (pdf) av Neoehrlichia mikurensis infection associated with lymphoma or mimicking lymphoma in two cohorts of Swedish patients
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Ingår i Physica medica (Testo stampato), 2026
- DOI för Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
- Ladda ner fulltext (pdf) av Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
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Ingår i Haematologica, s. 2356-2366, 2025
- DOI för A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma
- Ladda ner fulltext (pdf) av A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma
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Ingår i Blood Cancer Journal, 2025
- DOI för Advanced stage classical Hodgkin lymphoma patients with a positive interim-PET (PET-2) Deauville score 5 after 2 ABVD cycles: a pooled analysis of three multicenter trials
- Ladda ner fulltext (pdf) av Advanced stage classical Hodgkin lymphoma patients with a positive interim-PET (PET-2) Deauville score 5 after 2 ABVD cycles: a pooled analysis of three multicenter trials
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Ingår i HemaSphere, 2025
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Ingår i HemaSphere, 2025
- DOI för Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
- Ladda ner fulltext (pdf) av Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
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Ingår i The Lancet Oncology, s. 1081-1090, 2025
- DOI för Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial
- Ladda ner fulltext (pdf) av Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial
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Ingår i Acta Oncologica, s. 1540-1543, 2025
- DOI för Improved therapies, incomplete data: late toxicity after modern classical Hodgkin Lymphoma radiotherapy
- Ladda ner fulltext (pdf) av Improved therapies, incomplete data: late toxicity after modern classical Hodgkin Lymphoma radiotherapy
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Ingår i Physica medica (Testo stampato), 2025
- DOI för Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
- Ladda ner fulltext (pdf) av Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
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Ingår i Haematologica, s. 2866-2867, 2025
- DOI för Response to Comment on: "A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma"
- Ladda ner fulltext (pdf) av Response to Comment on: "A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma"
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Aging Kairos: treating older Hodgkin patients
Ingår i Blood, s. 943-945, 2024
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Ingår i The Lancet, s. 341-352, 2024
- DOI för Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial
- Ladda ner fulltext (pdf) av Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial
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Ingår i eJHaem, s. 1190-1200, 2024
- DOI för Congestive heart failure after anthracycline-containing treatment for Hodgkin lymphoma: A Swedish matched cohort study
- Ladda ner fulltext (pdf) av Congestive heart failure after anthracycline-containing treatment for Hodgkin lymphoma: A Swedish matched cohort study
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Diagnostik och behandling av klassiskt Hodgkins lymfom
Ingår i Läkartidningen, 2024
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Ingår i British Journal of Haematology, s. 1794-1803, 2024
- DOI för Evaluation of coverage, generalisability and validity of the U-CAN lymphoma biobank in Sweden: A comparison with nationwide registers
- Ladda ner fulltext (pdf) av Evaluation of coverage, generalisability and validity of the U-CAN lymphoma biobank in Sweden: A comparison with nationwide registers
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Ingår i Acta Oncologica, s. 164-168, 2024
- DOI för Impact of the COVID-19 pandemic on lymphoma incidence and short-term survival - a Swedish Lymphoma Register Study
- Ladda ner fulltext (pdf) av Impact of the COVID-19 pandemic on lymphoma incidence and short-term survival - a Swedish Lymphoma Register Study
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Ingår i Heliyon, 2024
- DOI för Improved automated tumor segmentation in whole-body 3D scans using multi-directional 2D projection-based priors
- Ladda ner fulltext (pdf) av Improved automated tumor segmentation in whole-body 3D scans using multi-directional 2D projection-based priors
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Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
Ingår i Journal of Clinical Oncology, s. 13-18, 2024
- DOI för Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
- Ladda ner fulltext (pdf) av Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial
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The National Swedish Lymphoma Register - a systematic validation of data quality
Ingår i Acta Oncologica, s. 563-572, 2024
- DOI för The National Swedish Lymphoma Register - a systematic validation of data quality
- Ladda ner fulltext (pdf) av The National Swedish Lymphoma Register - a systematic validation of data quality
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Ingår i Blood, s. 878-886, 2023
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NLPHL: a hummingbird in an owl's nest
Ingår i Blood, s. 499-500, 2023
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Ingår i International Journal of Cancer, s. 723-731, 2023
- DOI för Reproduction patterns among classical Hodgkin lymphoma survivors treated with BEACOPP and ABVD in Sweden, Denmark and Norway-A population-based matched cohort study
- Ladda ner fulltext (pdf) av Reproduction patterns among classical Hodgkin lymphoma survivors treated with BEACOPP and ABVD in Sweden, Denmark and Norway-A population-based matched cohort study
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Ingår i Blood Advances, s. 5304-5313, 2023
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An image registration method for voxel-wise analysis of whole-body oncological PET-CT
Ingår i Scientific Reports, 2022
- DOI för An image registration method for voxel-wise analysis of whole-body oncological PET-CT
- Ladda ner fulltext (pdf) av An image registration method for voxel-wise analysis of whole-body oncological PET-CT
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Checkpoint CD47 expression in classical Hodgkin lymphoma
Ingår i British Journal of Haematology, s. 580-589, 2022
- DOI för Checkpoint CD47 expression in classical Hodgkin lymphoma
- Ladda ner fulltext (pdf) av Checkpoint CD47 expression in classical Hodgkin lymphoma
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Ingår i Cancers, 2022
- DOI för Expression of PD-1, PD-L1 and PD-L2 in Lymphomas in Patients with Pre-Existing Rheumatic Diseases-A Possible Association with High Rheumatoid Arthritis Disease Activity
- Ladda ner fulltext (pdf) av Expression of PD-1, PD-L1 and PD-L2 in Lymphomas in Patients with Pre-Existing Rheumatic Diseases-A Possible Association with High Rheumatoid Arthritis Disease Activity
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Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
Ingår i Cancers, 2022
- DOI för Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
- Ladda ner fulltext (pdf) av Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
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Ingår i Journal of Clinical Oncology, s. 1487-1496, 2022
- DOI för Limited, But Not Eliminated, Excess Long-Term Morbidity in Stage I-IIA Hodgkin Lymphoma Treated With Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine and Limited-Field Radiotherapy
- Ladda ner fulltext (pdf) av Limited, But Not Eliminated, Excess Long-Term Morbidity in Stage I-IIA Hodgkin Lymphoma Treated With Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine and Limited-Field Radiotherapy
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Ingår i New Biotechnology, s. 21-29, 2022
- DOI för Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls
- Ladda ner fulltext (pdf) av Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls
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Ingår i Upsala Journal of Medical Sciences, 2021
- DOI för High risk of cardiovascular side effects after treatment of Hodgkin's lymphoma - is there a need for intervention in long-term survivors?
- Ladda ner fulltext (pdf) av High risk of cardiovascular side effects after treatment of Hodgkin's lymphoma - is there a need for intervention in long-term survivors?
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Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
Ingår i Cardio-Oncology, 2021
- DOI för Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
- Ladda ner fulltext (pdf) av Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
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Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
Ingår i Acta Oncologica, s. 771-778, 2021
- DOI för Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
- Ladda ner fulltext (pdf) av Prior antithymocyte globulin therapy and survival in post-transplant lymphoproliferative disorders
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Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
Ingår i Haematologica, s. 2502-2506, 2021
- DOI för Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
- Ladda ner fulltext (pdf) av Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma
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Ingår i eJHaem, s. 400-412, 2021
- DOI för Real-world data on treatment concepts in classical Hodgkin lymphoma in Sweden 2000-2014, focusing on patients aged >60 years
- Ladda ner fulltext (pdf) av Real-world data on treatment concepts in classical Hodgkin lymphoma in Sweden 2000-2014, focusing on patients aged >60 years
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Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma
Ingår i Blood Advances, s. 1671-1681, 2021
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Ingår i Upsala Journal of Medical Sciences, 2021
- DOI för Serum concentrations of Thymidine kinase 1 measured using a novel antibody-based assay in patients with Hodgkin Lymphoma
- Ladda ner fulltext (pdf) av Serum concentrations of Thymidine kinase 1 measured using a novel antibody-based assay in patients with Hodgkin Lymphoma
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CD30 expression and survival in posttransplant lymphoproliferative disorders
Ingår i Acta Oncologica, s. 673-680, 2020
- DOI för CD30 expression and survival in posttransplant lymphoproliferative disorders
- Ladda ner fulltext (pdf) av CD30 expression and survival in posttransplant lymphoproliferative disorders
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Ingår i British Journal of Haematology, s. 661-671, 2020
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Ingår i British Journal of Haematology, s. 685-691, 2020
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Pembrolizumab in relapsed or refractory Richter syndrome
Ingår i British Journal of Haematology, 2020
- DOI för Pembrolizumab in relapsed or refractory Richter syndrome
- Ladda ner fulltext (pdf) av Pembrolizumab in relapsed or refractory Richter syndrome
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Ingår i Leukemia and Lymphoma, s. 950-954, 2020
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Ingår i Immunobiology, 2020
- DOI för Precursor cells and implications of a T-cell inflamed immune response in the pre-malignant setting in Hodgkin lymphoma
- Ladda ner fulltext (pdf) av Precursor cells and implications of a T-cell inflamed immune response in the pre-malignant setting in Hodgkin lymphoma
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Ingår i Leukemia and Lymphoma, s. 376-384, 2019
- DOI för Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation
- Ladda ner fulltext (pdf) av Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation
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Ingår i British Journal of Haematology, s. 431-439, 2019
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Ingår i British Journal of Haematology, s. 192-201, 2019
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Ingår i Upsala Journal of Medical Sciences, s. 105-110, 2019
- DOI för Intratumoral expression of FoxP3-positive regulatory T-cells in T-cell lymphoma: no correlation with survival
- Ladda ner fulltext (pdf) av Intratumoral expression of FoxP3-positive regulatory T-cells in T-cell lymphoma: no correlation with survival
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Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087
Ingår i Blood, s. 1144-1153, 2019
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Ingår i European Journal of Haematology, s. 88-97, 2018
- DOI för An anergic immune signature in the tumor microenvironment of classical Hodgkin lymphoma is associated with inferior outcome
- Ladda ner fulltext (pdf) av An anergic immune signature in the tumor microenvironment of classical Hodgkin lymphoma is associated with inferior outcome
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Ingår i Annals of Hematology, s. 2129-2135, 2018
- DOI för Does the omission of vincristine in patients with diffuse large B cell lymphoma affect treatment outcome?
- Ladda ner fulltext (pdf) av Does the omission of vincristine in patients with diffuse large B cell lymphoma affect treatment outcome?
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Ingår i PLOS ONE, 2018
- DOI för Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma
- Ladda ner fulltext (pdf) av Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma
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Ingår i Acta Oncologica, s. 276-282, 2018
- DOI för Hodgkin lymphoma in children, adolescents and young adults - a comparative study of clinical presentation and treatment outcome.
- Ladda ner fulltext (pdf) av Hodgkin lymphoma in children, adolescents and young adults - a comparative study of clinical presentation and treatment outcome.
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Ingår i Blood Advances, s. 1427-1439, 2017
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Ingår i British Journal of Haematology, s. 449-456, 2017
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Ingår i Journal of Clinical Oncology, s. 2125-2132, 2017
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Ingår i Haematologica, s. 1-2, 2016
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Ingår i Haematologica, s. 36-36, 2016
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Ingår i Haematologica, s. 22-22, 2016
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Ingår i British Journal of Haematology, s. 236-244, 2016
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Ingår i Blood, s. 1531-1538, 2016
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Ingår i Haematologica, s. 3-3, 2016
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Ingår i Haematologica, s. 42-42, 2016
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Ingår i European Journal of Haematology, s. 430-438, 2016
- DOI för The role of tumour-infiltrating eosinophils, mast cells and macrophages in Classical and Nodular Lymphocyte Predominant Hodgkin Lymphoma in children
- Ladda ner fulltext (pdf) av The role of tumour-infiltrating eosinophils, mast cells and macrophages in Classical and Nodular Lymphocyte Predominant Hodgkin Lymphoma in children
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Ingår i Transplantation, s. 1036-1042, 2015
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Ingår i Clinical Radiology, s. 1229-1236, 2015
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Ingår i Acta Oncologica, s. 669-679, 2014
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Ingår i Blood, 2014
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Ingår i Acta Oncologica, s. 1271-1275, 2014
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Ingår i Histopathology, s. 26-32, 2012
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Long term risk of infections in Hodgkin lymphoma long-term survivors
Ingår i British Journal of Haematology, s. 661-663, 2011
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Pediatric Organ Transplantation and Risk of Premalignant and Malignant Tumors in Sweden
Ingår i American Journal of Transplantation, s. 146-151, 2011
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Ingår i European Journal of Haematology, s. 208-216, 2011
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The effect of Eosinophil cationic protein (ECP) on Hodgkin lymphoma cell lines
Ingår i Experimental Hematology, s. 850-858, 2011
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Whole-body diffusion-weighted imaging compared with FDG-PET/CT in staging of lymphoma patients
Ingår i Acta Radiologica, s. 173-180, 2011
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Ingår i Nature Genetics, s. 1126-1130, 2010
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Ingår i Acta Oncologica, s. 526-528, 2010
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Framgångens baksida: Sena biverkningar av strålbehandling vid Hodgkins lymfom
Ingår i Läkartidningen, s. 2731-2732, 2010
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Framgångens baksida: Sena biverkningar av strålbehandling vid Hodgkins lymfom
Ingår i Läkartidningen, s. 2731-2732, 2010
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Mast cells in squamous cell esophageal carcinoma and clinical parameters
Ingår i Cancer Genomics & Proteomics, s. 25-29, 2010
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Serum YKL-40 and interleukin 6 levels in Hodgkin lymphoma
Ingår i Clinical Cancer Research, s. 6974-8, 2008
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Cigarette smoking and risk of Hodgkin lymphoma: a population-based case-control study
Ingår i Cancer Epidemiology, Biomarkers and Prevention, s. 1561-1566, 2007
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Infectious mononucleosis, childhood social environment, and risk of Hodgkin lymphoma
Ingår i Cancer Research, s. 2382-2388, 2007
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Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma
Ingår i British Journal of Haematology, s. 68-71, 2007
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The potential role of innate immunity in the pathogenesis of Hodgkin's lymphoma
Ingår i Hematology/Oncology Clinics of North America, s. 805-823, 2007
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IL-9 expression contributes to the cellular composition in Hodgkin lymphoma
Ingår i European Journal of Haematology, s. 278-283, 2006
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Angiogenesis and mast cells in Hodgkin lymphoma
Ingår i Leukemia, s. 2360-2362, 2005
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Ingår i Scand J Infect Dis, s. 902-4, 2005
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Bystander cells and prognosis in Hodgkin lymphoma. Review based on a doctoral thesis.
Ingår i Ups J Med Sci, s. 179-228, 2004
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Ingår i Leukemia, s. 2513, 2003
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Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma
Ingår i British Journal of Haematology, s. 122-124, 2002
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