Daniel Fürth – Unlocking cellular symbolic information processing by optical and chemoselective innovations
We study how information is stored, processed, and transmitted between cells with a special focus on how aforementioned information processing enables computations in the nervous system. To do this we develop novel tools and techniques at the intersection of molecular biology and computer science.
Research
Understanding the nature of cell communication in health and disease remains one of the most important areas of biology. Our lab searches for hitherto unknown mechanism by which symbolic information can be transferred between cells. Identification of such transmission would enable us to read and write those messages.
Tools
Development of novel tools is an intricate part of our lab. We use and develop methods to read and write information at single molecule level. We combine nonlinear optical microscopy together with chemoselective moeities to develop new ways to perturb and interrogate information at the single-molecule level.
Whole-mount 3D single-molecule data at the transcriptome level necessitates new ways of compiling and analyzing anatomical data. We develop computational tools and resources for handling such data.
Group members
Publications
Part of Nature Biotechnology, 2024
- DOI for High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler
- Download full text (pdf) of High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler
