Publications

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Jerlström-Hultqvist, Jon; Warsi, Omar; Söderholm, Annika; Knopp, Michael et al.

Part of Nature Ecology & Evolution, p. 1321-1330, 2018

• DOI for A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Rao, Komal Umashankar; Henderson, Domhnall Iain; Krishnan, Nitya; Puthia, Manoj et al.

Part of Scientific Reports, 2021

• DOI for A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy
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A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections

Mezger, Anja; Gullberg, Erik; Goransson, Jenny; Zorzet, Anna et al.

Part of Journal of Clinical Microbiology, p. 425-432, 2015

• DOI for A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections
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A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Khan, David D.; Lagerbäck, Pernilla; Cao, Sha; Lustig, Ulrika et al.

Part of Journal of Antimicrobial Chemotherapy, p. 3051-3060, 2015

• DOI for A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Tang, Po-Cheng; Eriksson, Olle; Sjögren, Josefin; Fatsis-Kavalopoulos, Nikos et al.

Part of Frontiers in Cellular and Infection Microbiology, 2022

• DOI for A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms
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A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

Geli, Patricia; Andersson, Mikael; Svensson, Åke; Andersson, Dan I

Part of Journal of Theoretical Biology, p. 58-64, 2009

• DOI for A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

A novel type of colistin resistance genes selected from random sequence space

Knopp, Michael; Babina, Arianne M.; Gudmundsdottir, Jonina S.; Douglass, Martin, V et al.

Part of PLOS Genetics, 2021

• DOI for A novel type of colistin resistance genes selected from random sequence space
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A portable epigenetic switch for bistable gene expression in bacteria

Olivenza, David R.; Nicoloff, Hervé; Antonia Sanchez-Romero, Maria; Cota, Ignacio et al.

Part of Scientific Reports, 2019

• DOI for A portable epigenetic switch for bistable gene expression in bacteria
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Activation of cryptic aminoglycoside resistance in Salmonella enterica

Koskiniemi, Sanna; Pränting, Maria; Gullberg, Erik; Näsvall, Joakim et al.

Part of Molecular Microbiology, p. 1464-1478, 2011

• DOI for Activation of cryptic aminoglycoside resistance in Salmonella enterica

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Pavlov, Michael Y.; Zorzet, Anna; Andersson, Dan I.; Ehrenberg, Måns

Part of EMBO Journal, p. 289-301, 2011

• DOI for Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Maisnier-Patin, Sophie; Andersson, Dan I

Part of Research in Microbiology, p. 360-369, 2004

• DOI for Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Roth, John R; Andersson, Dan I

Part of Journal of Bacteriology, p. 4855-4860, 2004

• DOI for Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Adventures with mutation and selection in beehive and cow country

Hughes, Diarmaid; Andersson, Dan I

Part of The Lure of Bacterial Genetics, p. 245-253, ASM Press, 2010

Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Thulin, Elisabeth; Sundqvist, Martin; Andersson, Dan I.

Part of Antimicrobial Agents and Chemotherapy, p. 1723-1732, 2015

• DOI for Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

Knopp, Michael; Andersson, Dan I.

Part of Molecular biology and evolution, p. 3252-3263, 2015

• DOI for Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Paulander, Wilhelm; Andersson, Dan I.; Maisnier-Patin, Sophie

Part of Genetics, p. 305-312, 2010

• DOI for Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

Roth, John R; Andersson, Dan I

Part of Research in Microbiology, p. 342-351, 2004

• DOI for Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance

Ancillotti, Mirko; Eriksson, Stefan; Godskesen, Tove; Andersson, Dan I. et al.

Part of Public Health Ethics, p. 1-11, 2021

• DOI for An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance
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Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Hjort, Karin; Fermér, Elin; Tang, Po-Cheng; Andersson, Dan I.

Part of mBio, 2022

• DOI for Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Antibiotic resistance and its cost: is it possible to reverse resistance?

Andersson, Dan I.; Hughes, Diarmaid

Part of Nature Reviews Microbiology, p. 260-271, 2010

• DOI for Antibiotic resistance and its cost: is it possible to reverse resistance?

Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Part of Microbiology Spectrum, 2024

• DOI for Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids
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Antibiotic resistance: turning evolutionary principles into clinical reality

Andersson, Dan I.; Balaban, Nathalie Q.; Baquero, Fernando; Courvalin, Patrice et al.

Part of FEMS Microbiology Reviews, p. 171-188, 2020

• DOI for Antibiotic resistance: turning evolutionary principles into clinical reality

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Baltekin, Özden; Boucharin, Alexis; Tano, Eva; Andersson, Dan I et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9170-9175, 2017

• DOI for Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Wiuff, Camilla; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 254-263, 2007

• DOI for Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics

Blanco, Paula; Hjort, Karin; Martinez, Jose L.; Andersson, Dan I

Part of mSphere, 2020

• DOI for Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics
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Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides

Kubicek-Sutherland, Jessica Z.; Lofton, Hava; Vestergaard, Martin; Hjort, Karin et al.

Part of Journal of Antimicrobial Chemotherapy, p. 115-127, 2017

• DOI for Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides
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Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Pal, Ankita; Andersson, Dan I.

Part of Nature Communications, 2024

• DOI for Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
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Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Gustafsson, Ingegerd; Sjölund, Maria; Torell, Erik; Johannesson, Marie et al.

Part of Journal of Antimicrobial Chemotherapy, p. 645-650, 2003

• DOI for Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Bacterial gene amplification: implications for the evolution of antibiotic resistance

Sandegren, Linus; Andersson, Dan I.

Part of Nature Reviews Microbiology, p. 578-588, 2009

• DOI for Bacterial gene amplification: implications for the evolution of antibiotic resistance

Bacterial genome size reduction by experimental evolution

Nilsson, A I; Koskiniemi, Sanna; Eriksson, S; Kugelberg, E et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 12112-12116, 2005

• DOI for Bacterial genome size reduction by experimental evolution

Bacterial Resistance To A Cyclic Antimicrobial Peptide

Malik, Sohaib Zafar; Göransson, Ulf; Andersson, Dan I

Part of Journal of Peptide Science, 2016

• DOI for Bacterial Resistance To A Cyclic Antimicrobial Peptide

Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Luis Martinez, Jose; Baquero, Fernando; Andersson, Dan I.

Part of Current opinion in pharmacology (Print), p. 439-445, 2011

• DOI for Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

Fatsis-Kavalopoulos, Nikos; Sánchez-Hevia, Dione; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 2394-2396, 2024

• DOI for Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)
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Biological roles of translesion synthesis DNA polymerases in eubacteria

Andersson, Dan I.; Koskiniemi, Sanna; Hughes, Diarmaid

Part of Molecular Microbiology, p. 540-548, 2010

• DOI for Biological roles of translesion synthesis DNA polymerases in eubacteria

Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Paulander, Wilhelm; Pennhag, Alexandra; Andersson, Dan I.; Maisnier-Patin, Sophie

Part of Antimicrobial Agents and Chemotherapy, p. 766-769, 2007

• DOI for Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Nielsen, Elisabet I.; Khan, David D.; Cao, Sha; Lustig, Ulrika et al.

Part of Journal of Antimicrobial Chemotherapy, p. 3108-3116, 2017

• DOI for Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.

Roemhild, Roderich; Gokhale, Chaitanya S; Dirksen, Philipp; Blake, Christopher et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9767-9772, 2018

• DOI for Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.
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Characterization of Resitant Mutants Points Towards Mechanism of Action of Cyclotides

Malik, Sohaib Zafar; Andersson, Dan I.; Göransson, Ulf

Part of Journal of Peptide Science, 2014

Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase

Rosenkilde, Carola E. H.; Munck, Christian; Porse, Andreas; Linkevicius, Marius et al.

Part of Nature Communications, 2019

• DOI for Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase
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CombiANT: Antibiotic interaction testing made easy

Fatsis-Kavalopoulos, Nikos; Römhild, Roderich; Tang, Po-Cheng; Kreuger, Johan et al.

Part of PLoS biology, 2020

• DOI for CombiANT: Antibiotic interaction testing made easy
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CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions

Hallström, Erik; Fatsis-Kavalopoulos, Nikos; Bimpis, Manos; Wählby, Carolina et al.

Part of PLOS Digital Health, 2025

• DOI for CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions
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Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Adler, Marlen; Anjum, Mehreen; Andersson, Dan I.; Sandegren, Linus

Part of Journal of Antimicrobial Chemotherapy, p. 1188-1198, 2016

• DOI for Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

Starck, Joakim; Källenius, Gunilla; Marklund, Britt-Inger; Andersson, Dan I et al.

Part of Microbiology, p. 3821-3829, 2004

• DOI for Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

Compensating the fitness costs of synonymous mutations

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Part of Molecular biology and evolution, p. 1461-1477, 2016

• DOI for Compensating the fitness costs of synonymous mutations
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Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Maisnier-Patin, S; Paulander, W; Pennhag, A; Andersson, Dan I.

Part of Journal of Molecular Biology, p. 207-215, 2007

• DOI for Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Compensatory gene amplification restores fitness after inter-species gene replacements

Lind, Peter A; Tobin, Christina; Berg, Otto G; Kurland, Charles G et al.

Part of Molecular Microbiology, p. 1078-1089, 2010

• DOI for Compensatory gene amplification restores fitness after inter-species gene replacements

Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Zorzet, Anna; Andersen, Jytte Mark; Nilsson, Annika I; Møller, Niels Frimodt et al.

Part of Journal of Antimicrobial Chemotherapy, p. 1835-1842, 2012

• DOI for Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

Sun, Song; Berg, Otto G; Andersson, Dan I; Roth, John R

Part of Genetics, p. 1183-1195, 2009

• DOI for Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

De Novo Emergence of Peptides That Confer Antibiotic Resistance

Knopp, Michael; Gudmundsdottir, Jonina S.; Nilsson, Tobias; Konig, Finja et al.

Part of mBio, 2019

• DOI for De Novo Emergence of Peptides That Confer Antibiotic Resistance
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Definitions and guidelines for research on antibiotic persistence

Balaban, Nathalie Q.; Helaine, Sophie; Lewis, Kim; Ackermann, Martin et al.

Part of Nature Reviews Microbiology, p. 441-448, 2019

• DOI for Definitions and guidelines for research on antibiotic persistence
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